Identifiers and Description

Gene Model Identifier

TTHERM_00655560

Standard Name

GND1 (6-phosphoGlucoNate Dehydrogenase 1)

Aliases

PreTt03654 | 96.m00123

Description

GND1 NAD-binding domain of 6-phosphogluconate dehydrogenase family protein; 6-phosphogluconate dehydrogenase (decarboxylating); catalyzes an NADPH-regenerating reaction in the pentose phosphate pathway

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Molecular Function

• phosphogluconate dehydrogenase (decarboxylating) activity (IEA) | GO:0004616

Biological Process

• obsolete oxidation-reduction process (IEA) | GO:0055114
• pentose-phosphate shunt (IEA) | GO:0006098

Domains

• ( PF01488 ) Shikimate / quinate 5-dehydrogenase
• ( PF02153 ) prephenate dehydrogenase
• ( PF02737 ) 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain
• ( PF02826 ) erythronate-4-phosphate dehydrogenase
• ( PF03446 ) NAD binding domain of 6-phosphogluconate
• ( PF03807 ) NADP oxidoreductase coenzyme F420-dependent
• ( PF07991 ) Acetohydroxy acid isomeroreductase, catalytic domain
• ( TIGR00112 ) pyrroline-5-carboxylate reductase
• ( TIGR00872 ) 6-phosphogluconate dehydrogenase (decarboxylating)
• ( TIGR00873 ) 6-phosphogluconate dehydrogenase, decarboxylating
• ( TIGR01505 ) 2-hydroxy-3-oxopropionate reductase
• ( TIGR01692 ) 3-hydroxyisobutyrate dehydrogenase
• ( TIGR03026 ) nucleotide sugar dehydrogenase

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_18003.1	9.997093137033517e-262
	Description: NAD binding domain-6-phosphogluconate dehydrogenase (302 aa)
Oxytricha	Contig10468.0.g95	6.000220702367707e-121
	Description: NAD binding domain of 6-phosphogluconate dehydrogenase
Stentor Coeruleus	SteCoe_386	2.572209372642415e-56
	Description: None
DictyBase	DDB_G0292566	4.00073564232477e-35
	Description: hibA on chromosome: 6 position 1891263 to 1892228
WormBase	WBGene00007122	1.999790113608142e-24
	Description: Probable 3-hydroxyisobutyrate dehydrogenase, mitochondrial status:Confirmed UniProt:Q9XTI0 protein_id:CAB03798.1
SGD	YGR256W	0.000000000006001570085597868
	Description: GND2 6-phosphogluconate dehydrogenase (decarboxylating), catalyzes an NADPH regenerating reaction in the pentose phosphate pathway; required for growth on D-glucono-delta-lactone

General Information

No Data fetched for General Information

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_00655560(coding)
ATGGCTTAGTCTGCAATTAAAACTATCGGTTGGATTGGAACTGGTGTTATGGGTAAGTCT
ATGTGCTTACATTTGTTAAACGCTGGTTTCTAGCTAAATGTTTACAATAGAACTGCTAGT
AAGGCTGACGAATTAGTCAGTAAAGGAGCCAAGTTTTTAGCTCCTGAAGATTTAGCTAAA
AATTCTGATGTAGTATTTTTGATGCTTGGTTATCCTCATGATGTCTAATAAATGGTATTA
GGTGAATAAGGAATTTTAAAGCACATGAAAAAAGGTTCCTTATTGATTGACCACACTACA
TCCGCTCCTTCTCTTGCTGTAGAAATTGCAGCCGAAGCATAAAAGTATGGAATCGAAAGT
ATTGATGCCCCAGTTAGTGGAGGTGATATCGGAGCTAGAGAAGCTAGATTAGCAATTATG
TGTGGCGGTTCCCAAGCTGCTTTTGATCTTGCTCTTCCTATTTTATAAAAGTATGGTGCA
AATATCTAATTATTAGGTGGCGCAGGAGCAGGATAACACACCAAAATGACTAATTAAATT
TTATTAGCTAGCAATATGTTAGGTGTTGTTGAAGGCTTACTCTATGCTCATAAGGCTGGA
TTAGATTTAGATTAAGTAATTAATCTTATTAAGACTGGTGCTGCCTCATCTACTGCATGG
CACGTTCTTGGCTCAAGAATGGTTAAGCGTGACTTTGAACCTGGCTTCTATGTAGAGCAT
TTTATTAAGGATATGGATATTGCCTTAGAAGAGGCCAAAAGAGCTAACTTATGTCTCCCT
GGATTAGGCTTAGTAAAGTAATTTTATCATGCCTTAGTTGCATAAGGAGGTGCTCGTAAT
GGAACTTAAGCTATCATTAAAGTTTTAGAATAAATGAACAATGTTTAAATCGGAAAGAAA
TAATGA

>TTHERM_00655560(gene)
ATGGCTTAGTCTGCAATTAAAACTATCGGTTGGATTGGAACTGGTGTTATGGGTAAGTCT
ATGTGCTTACATTTGTTAAACGCTGGTTTCTAGCTAAATGTTTACAATAGAACTGCTAGT
AAGGCTGACGAATTAGTCAGTAAAGGAGCCAAGTTTTTAGCTCCTGAAGATTTAGCTAAA
AATTCTGATGTAGTATTTTTGATGCTTGGTTATCCTCATGATGTCTAATAAATGGTATTA
GGTGAATAAGGAATTTTAAAGCACATGAAAAAAGGTTCCTTATTGATTGACCACACTACA
TCCGCTCCTTCTCTTGCTGTAGAAATTGCAGCCGAAGCATAAAAGTATGGAATCGAAAGT
ATTGATGCCCCAGTTAGTGGAGGTGATATCGGAGCTAGAGAAGCTAGATTAGCAATTATG
TGTGGCGGTTCCCAAGCTGCTTTTGATCTTGCTCTTCCTATTTTATAAAAGTATGGTGCA
AATATCTAATTATTAGGTGGCGCAGGAGCAGGATAACACACCAAAATGACTAATTAAATT
TTATTAGCTAGCAATATGTTAGGTGTTGTTGAAGGCTTACTCTATGCTCATAAGGCTGGA
TTAGATTTAGATTAAGTAATTAATCTTATTAAGACTGGTGCTGCCTCATCTACTGCATGG
CACGTTCTTGGCTCAAGAATGGTTAAGCGTGACTTTGAAGTAAATTCTTTAATAATAAAC
ATTCTAAAATTCTATTAAAATACAAAAAAAATAAGATATATTTTAACAAAGCTATAATTT
ATAAAATATCTTTTTTGATGATAAAAATTTTGTTTTTTAAATCTTTGTTTTTCTTAGTTT
AATTATTTTTATTAAATAATAGCCTGGCTTCTATGTAGAGCATTTTATTAAGGATATGGA
TATTGCCTTAGAAGAGGCCAAAAGAGCTAACTTATGTCTCCCTGGATTAGGCTTAGTAAA
GTAATTTTATCATGCCTTAGTTGCATAAGGAGGTGCTCGTAATGGAACTTAAGCTATCAT
TAAAGTTTTAGAATAAATGAACAATGTTTAAATCGGAAAGAAATAATGA

>TTHERM_00655560(protein)
MAQSAIKTIGWIGTGVMGKSMCLHLLNAGFQLNVYNRTASKADELVSKGAKFLAPEDLAK
NSDVVFLMLGYPHDVQQMVLGEQGILKHMKKGSLLIDHTTSAPSLAVEIAAEAQKYGIES
IDAPVSGGDIGAREARLAIMCGGSQAAFDLALPILQKYGANIQLLGGAGAGQHTKMTNQI
LLASNMLGVVEGLLYAHKAGLDLDQVINLIKTGAASSTAWHVLGSRMVKRDFEPGFYVEH
FIKDMDIALEEAKRANLCLPGLGLVKQFYHALVAQGGARNGTQAIIKVLEQMNNVQIGKK
Q