Identifiers and Description

Gene Model Identifier

TTHERM_00674500

Standard Name

UDH8 (UvrD/REP-family DNA helicase 8)

Aliases

PreTt10990 | 101.m00145 | REP14

Description

UDH8 UvrD/REP helicase family protein; UvrD/REP-family DNA helicase; DNA helicase, UvrD/REP type

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Cellular Component

• ionotropic glutamate receptor complex (IEA) | GO:0008328
• obsolete integral component of mitochondrial membrane (IEA) | GO:0032592
• serine/threonine protein kinase complex (IEA) | GO:1902554

Molecular Function

• 11-deoxycorticosterone binding (IEA) | GO:1903878
• 17alpha-hydroxyprogesterone binding (IEA) | GO:1903880
• 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity (IEA) | GO:0008413
• amino acid:monoatomic cation symporter activity (IEA) | GO:0005416
• icosanoid receptor activity (IEA) | GO:0004953
• L-arabinokinase activity (IEA) | GO:0009702
• obsolete sodium-transporting two-sector ATPase activity (IEA) | GO:0015443
• phosphatidylinositol-3-phosphate binding (IEA) | GO:0032266
• phosphatidylserine decarboxylase activity (IEA) | GO:0004609
• phosphoenolpyruvate carboxykinase (GTP) activity (IEA) | GO:0004613
• sphingomyelin phosphodiesterase activity (IEA) | GO:0004767
• tRNA threonylcarbamoyladenosine dehydratase (IEA) | GO:0061503
• type 4 neuropeptide Y receptor binding (IEA) | GO:0031844

Biological Process

• cell wall modification involved in fruit ripening (IEA) | GO:0009829
• glycolytic process from mannose through fructose-6-phosphate (IEA) | GO:0061619
• heme A biosynthetic process (IEA) | GO:0006784
• heme biosynthetic process (IEA) | GO:0006783
• immunoglobulin heavy chain V-D-J recombination (IEA) | GO:0071707
• induction of apoptosis by extracellular signals (IEA) | GO:0008624
• interleukin-19 production (IEA) | GO:0032622
• interleukin-2 production (IEA) | GO:0032623
• mitochondrial genome maintenance (IEA) | GO:0000002
• negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process (IEA) | GO:1902647
• negative regulation of complement-dependent cytotoxicity (IEA) | GO:1903660
• negative regulation of epithelial cell-cell adhesion involved in epithelium migration (IEA) | GO:1903682
• negative regulation of interleukin-1 production (IEA) | GO:0032692
• negative regulation of PERK-mediated unfolded protein response (IEA) | GO:1903898
• obsolete activation of pro-apoptotic gene products (IEA) | GO:0008633
• obsolete modification by symbiont of host morphology or physiology via protein secreted by type VII secretion system (IEA) | GO:0085023
• obsolete negative regulation of catalase activity (IEA) | GO:1902552
• obsolete negative regulation of histone H3-K18 acetylation (IEA) | GO:1902030
• obsolete primary charge separation in photosystem I (IEA) | GO:0009770
• obsolete regulation of histone H3-K27 methylation (IEA) | GO:0061085
• ommochrome biosynthetic process (IEA) | GO:0006727
• P granule assembly (IEA) | GO:1903863
• phagocytosis (IEA) | GO:0006909
• phagocytosis, engulfment (IEA) | GO:0006911
• plant-type cell wall modification (IEA) | GO:0009827
• polyamine acetylation (IEA) | GO:0032917
• positive regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process (IEA) | GO:1902643
• positive regulation of response to water deprivation (IEA) | GO:1902584
• pronuclear fusion (IEA) | GO:0007344
• propan-2-ol biosynthetic process (IEA) | GO:1902640
• protein localization to old growing cell tip (IEA) | GO:1903858
• prothoracic disc morphogenesis (IEA) | GO:0007470
• regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process (IEA) | GO:1902641
• regulation of complement-dependent cytotoxicity (IEA) | GO:1903659
• regulation of cytokinin dehydrogenase activity (IEA) | GO:1903856
• regulation of germ cell proliferation (IEA) | GO:1905936
• substrate-dependent cell migration, cell attachment to substrate (IEA) | GO:0006931
• tertiary alcohol biosynthetic process (IEA) | GO:1902645
• trachea gland development (IEA) | GO:0061153
• visceral muscle development (IEA) | GO:0007522

Domains

• ( PF13245 ) AAA domain
• ( PF13361 ) UvrD-like helicase C-terminal domain

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

No Data fetched for Homologs

General Information

No Data fetched for General Information

Associated Literature

1. Ref:23884606: Gao S, Xiong J, Zhang C, Berquist BR, Yang R, Zhao M, Molascon AJ, Kwiatkowski SY, Yuan D, Qin Z, Wen J, Kapler GM, Andrews PC, Miao W, Liu Y (2013) Impaired replication elongation in Tetrahymena mutants deficient in histone H3 Lys 27 monomethylation. Genes & development 27(15):1662-79

Sequences

>TTHERM_00674500(coding)
ATGTAGTAACTCAAGAGTGATTTAGATCGTTTTACTGACGATTAAAAGAAGTTTATTTTA
TCTCCAAAAAATGTAGATATCAAAGTCAATGCTTGCGCTGGATCTGGAAAAACTGAATGC
ATTCTTTAATTTGTAAAATAGGCTAGATTGAGTGGAATTAATTATAAGCAAATTTGCATT
ACTACGTTTAACATCTAAGCAATAAATGATATACATAAAAGAGCAGTCGATTTATTTGGT
GAAGAATTAGCTGATGAGATAGAAATTAAAAACTTTGATAAATTAATAACTAAATCTTAT
GAATCAATCAAAACTTTATAAAATCCTTAACAAAAAGATATTTTTACAGAAGAGGTAGAT
ATTACCTTAGTTGAAAAATAATTTGAGCTAGTGAACATGGATTACTAAAATTTAGGTAAG
GATGATAAAATGTAAATCTTTGGCGCATATAAAATAATTATTTTTGATGAATTTTAAGAT
ATTAATGAACTTTAATACAGCTTTTTATTGCTATTCAAAAAATATGGAGGATCAAACATC
GTTGTAGTTGGAGATGTATTTTAAAATATTTATCAATTTAGAGGATCAGATTAAAAATAT
TTGAGTAATCAAATTAATCAAGACATTCAAAGTATAAACTAAAATTTGAAAAAGAGGGAT
TAAAAAATTATAGATCTTAGTTTATCTATAAACTTTAGATGTTCCTAGGAAATAACTTTT
TTTGCAAATGAAATAATTAAATGCTAAAATGAGAATTCAAATTTAATGAAATCCTTTTAA
GAGTTGAATAATTCAAACAATGAAATTAAGAAGAAGTAGATTCCTTTTTTAGAAGGTTTT
ATGAGTAATAAAGATTAATTTAAAAGTATTGTCAAATCAATAAATACTTACATTGAAGAA
GGATATTCATATGACGATATAGCTATAATTAGTCCAATTTAAGCATCTCTTAAGGAAATA
GAGTACCTTATTGAAGAACAAAATCATAAAATAAAATAAAACCCAGACAAAAATAAAGAT
AAAAAGATAATACCTTATTACAGTGTAATAGGAGATAGTTCTAATTTTGATTGTAAGCAT
CAATTTAAATAAAAAAATAAAATTTCGCTGTCAACTGTCCATAGAGCAAAAGGATTAGAA
TGGAAAATAGTATTCTTTATTGGATTGAATGATGATGTAATTCCTATGTCATTTTTAAGA
TAAGGTGACTTGAAATAGAAAATGGAAGAAATGAGGCGTCTATTTTATGTTGGATGCACA
AGATCTGCAGAAATACTGAAAATGTTCTATTTTTGTAATAATTAAAGAAAAGCATCGCGA
TTATTCAAAAATATAAGCAAAGAATCATATTCTAAGGATGAAAATGTTATAATAGAAGAA
GATGATGACAAATTCTATGAAGAGAAATAAAATAATAAAAAATTTTCATATAGAATTAGT
GATTTTTTTGATAATTTAAGCAATATTTAGTATATCAATCATCTAAAATAATCCTAATAA
TATCTTAAAGATATTTATGTCAGCGAAATAGAAATATTCAATAAATAGCATACTCTTAGC
GAATAATAGATACAATTGATATTTTCAGAATAGTAACAAAACTTGCTATTCAATTACATA
TAAATAATTCTTTTAGAAAAAAGTAAGAAATAAGTTTAGCTCACTAAAGAAGCTTACTAT
TTATAGAAAATAAAATAGAAAATATAAAATTTATAAGAACATAATTACCTATAAAATATG
CTTAAATTATTCAAAGACAATAATTAATCTTTAGAGAGAAATCAAAAAGAGCTTTATGAA
GCTATTTATAAAGCATGTATCTTTTTAGAAGTAAAAAAATCAAATTAGTTTAAATATATT
TTCTACCAAGATCCCTATAAAGAATAAGAAAAAATCATAAACTGCTTAAAGAAAATGTTG
GATACTTGTTTTAAAAAGTAAGATTATTAAGATCTCCTTATTTAAGATTATATTGAAAAA
GATAAATTTTATGATTATGAAACCTTCTCAAGTAAAGACACAATCTATGAAATCATATAA
TCTTTTGAAAAACAAACAGTTGGAAAATAAGTTATGCTAACAGTTTTAGGGAAAATATCT
ATCCTTAAAGTAAAATATTAGAGAGATATTAAAAATATATTATTCTACAATCCGATATAA
GGAACGTCTGTCAAATACTCTCTATCTAATTGGAATTTTCATGATCAATTTATTTCATAT
ATGGAAGATATTATAAAATAAGAAAGTGATTAAAATAACTTGAATTAATGTTCAAGTTAA
TCCTTTTAAAATGTATCAAATATTTAGAAAAAAAAAGATGAATAGAATTCTAGTATCAAT
ATAAAATTAAATTAAATTCAGCAGGAAATAAGTTCGTCTAAATTTAAAGATTAGGTTTAA
AATAAAAACAATTTAATCATAGACTTAGAATAATCACCAACCGTTTTAGATTATAACTAA
AAAAAGGGGAAATTAATACATGCTGCTCCATTTTAATAAGAACCTGGTCTTTCTAAAAGG
CTTCATTTTGAACAGGATGAATCTTTCGGTTTAAGAAACTGA

>TTHERM_00674500(gene)
CTTTCACTGAAAAAAAGTAAAGTATGTAGTAACTCAAGAGTGATTTAGATCGTTTTACTG
ACGATTAAAAGAAGTTTATTTTATCTCCAAAAAATGTAGATATCAAAGTCAATGCTTGCG
CTGGATCTGGAAAAACTGAATGCATTCTTTAATTTGTAAAATAGGCTAGATTGAGTGGAA
TTAATTATAAGCAAATTTGCATTACTACGTTTAACATCTAAGCAATAAATGATATACATA
AAAGAGCAGTCGATTTATTTGGTGAAGAATTAGCTGATGAGATAGAAATTAAAAACTTTG
ATAAATTAATAACTAAATCTTATGAATCAATCAAAACTTTATAAAATCCTTAACAAAAAG
ATATTTTTACAGAAGAGGTAGATATTACCTTAGTTGAAAAATAATTTGAGCTAGTGAACA
TGGATTACTAAAATTTAGGTAAGGATGATAAAATGTAAATCTTTGGCGCATATAAAATAA
TTATTTTTGATGAATTTTAAGATATTAATGAACTTTAATACAGCTTTTTATTGCTATTCA
AAAAATATGGAGGATCAAACATCGTTGTAGTTGGAGATGTATTTTAAAATATTTATCAAT
TTAGAGGATCAGATTAAAAATATTTGAGTAATCAAATTAATCAAGACATTCAAAGTATAA
ACTAAAATTTGAAAAAGAGGGATTAAAAAATTATAGATCTTAGTTTATCTATAAACTTTA
GATGTTCCTAGGAAATAACTTTTTTTGCAAATGAAATAATTAAATGCTAAAATGAGAATT
CAAATTTAATGAAATCCTTTTAAGAGTTGAATAATTCAAACAATGAAATTAAGAAGAAGT
AGATTCCTTTTTTAGAAGGTTTTATGAGTAATAAAGATTAATTTAAAAGTATTGTCAAAT
CAATAAATACTTACATTGAAGAAGGATATTCATATGACGATATAGCTATAATTAGTCCAA
TTTAAGCATCTCTTAAGGAAATAGAGTACCTTATTGAAGAACAAAATCATAAAATAAAAT
AAAACCCAGACAAAAATAAAGATAAAAAGATAATACCTTATTACAGTGTAATAGGAGATA
GTTCTAATTTTGATTGTAAGCATCAATTTAAATAAAAAAATAAAATTTCGCTGTCAACTG
TCCATAGAGCAAAAGGATTAGAATGGAAAATAGTATTCTTTATTGGATTGAATGATGATG
TAATTCCTATGTCATTTTTAAGATAAGGTGACTTGAAATAGAAAATGGAAGAAATGAGGC
GTCTATTTTATGTTGGATGCACAAGATCTGCAGAAATACTGAAAATGTTCTATTTTTGTA
ATAATTAAAGAAAAGCATCGCGATTATTCAAAAATATAAGCAAAGAATCATATTCTAAGG
ATGAAAATGTTATAATAGAAGAAGATGATGACAAATTCTATGAAGAGAAATAAAATAATA
AAAAATTTTCATATAGAATTAGTGATTTTTTTGATAATTTAAGCAATATTTAGTATATCA
ATCATCTAAAATAATCCTAATAATATCTTAAAGATATTTATGTCAGCGAAATAGAAATAT
TCAATAAATAGCATACTCTTAGCGAATAATAGATACAATTGATATTTTCAGAATAGTAAC
AAAACTTGCTATTCAATTACATATAAATAATTCTTTTAGAAAAAAGTAAGAAATAAGTTT
AGCTCACTAAAGAAGCTTACTATTTATAGAAAATAAAATAGAAAATATAAAATTTATAAG
AACATAATTACCTATAAAATATGCTTAAATTATTCAAAGACAATAATTAATCTTTAGAGA
GAAATCAAAAAGAGCTTTATGAAGCTATTTATAAAGCATGTATCTTTTTAGAAGTAAAAA
AATCAAATTAGTTTAAATATATTTTCTACCAAGATCCCTATAAAGAATAAGAAAAAATCA
TAAACTGCTTAAAGAAAATGTTGGATACTTGTTTTAAAAAGTAAGATTATTAAGATCTCC
TTATTTAAGATTATATTGAAAAAGATAAATTTTATGATTATGAAACCTTCTCAAGTAAAG
ACACAATCTATGAAATCATATAATCTTTTGAAAAACAAACAGTTGGAAAATAAGTTATGC
TAACAGTTTTAGGGAAAATATCTATCCTTAAAGTAAAATATTAGAGAGATATTAAAAATA
TATTATTCTACAATCCGATATAAGGAACGTCTGTCAAATACTCTCTATCTAATTGGAATT
TTCATGATCAATTTATTTCATATATGGAAGATATTATAAAATAAGAAAGTGATTAAAATA
ACTTGAATTAATGTTCAAGTTAATCCTTTTAAAATGTATCAAATATTTAGAAAAAAAAAG
ATGAATAGAATTCTAGTATCAATATAAAATTAAATTAAATTCAGCAGGAAATAAGTTCGT
CTAAATTTAAAGATTAGGTTTAAAATAAAAACAATTTAATCATAGACTTAGAATAATCAC
CAACCGTTTTAGATTATAACTAAAAAAAGGGGAAATTAATACATGCTGCTCCATTTTAAT
AAGAACCTGGTCTTTCTAAAAGGCTTCATTTTGAACAGGATGAATCTTTCGGTTTAAGAA
ACTGAAATATTTATAATATAGAAAGGGGAAATTAATACATGCTGCTCCATTTTAATAAGA
ACCTGGTCTTTCTAAAAGGCTTCATTTTGAACAGGATGAATCTTTCGGTTTAAGAAACTG
AAATATTTATAATATAGTTAGATAAAATATTTTATTTCAAACAGTAATTATTATTAAAAA
AAGAAAATAAAATAATTATTTAAATAATAACATTTTCACTTTAAATTTATGTTTGTTTAT
TCATTTATAATTAACTCCTTCATAATTAAAAAAATTAATTTTTTTTGTTTATAAA

>TTHERM_00674500(protein)
MQQLKSDLDRFTDDQKKFILSPKNVDIKVNACAGSGKTECILQFVKQARLSGINYKQICI
TTFNIQAINDIHKRAVDLFGEELADEIEIKNFDKLITKSYESIKTLQNPQQKDIFTEEVD
ITLVEKQFELVNMDYQNLGKDDKMQIFGAYKIIIFDEFQDINELQYSFLLLFKKYGGSNI
VVVGDVFQNIYQFRGSDQKYLSNQINQDIQSINQNLKKRDQKIIDLSLSINFRCSQEITF
FANEIIKCQNENSNLMKSFQELNNSNNEIKKKQIPFLEGFMSNKDQFKSIVKSINTYIEE
GYSYDDIAIISPIQASLKEIEYLIEEQNHKIKQNPDKNKDKKIIPYYSVIGDSSNFDCKH
QFKQKNKISLSTVHRAKGLEWKIVFFIGLNDDVIPMSFLRQGDLKQKMEEMRRLFYVGCT
RSAEILKMFYFCNNQRKASRLFKNISKESYSKDENVIIEEDDDKFYEEKQNNKKFSYRIS
DFFDNLSNIQYINHLKQSQQYLKDIYVSEIEIFNKQHTLSEQQIQLIFSEQQQNLLFNYI
QIILLEKSKKQVQLTKEAYYLQKIKQKIQNLQEHNYLQNMLKLFKDNNQSLERNQKELYE
AIYKACIFLEVKKSNQFKYIFYQDPYKEQEKIINCLKKMLDTCFKKQDYQDLLIQDYIEK
DKFYDYETFSSKDTIYEIIQSFEKQTVGKQVMLTVLGKISILKVKYQRDIKNILFYNPIQ
GTSVKYSLSNWNFHDQFISYMEDIIKQESDQNNLNQCSSQSFQNVSNIQKKKDEQNSSIN
IKLNQIQQEISSSKFKDQVQNKNNLIIDLEQSPTVLDYNQKKGKLIHAAPFQQEPGLSKR
LHFEQDESFGLRN