Identifiers and Description

Gene Model Identifier

TTHERM_00678310

Standard Name

Aliases

PreTt07595 | 102.m00115 | 3730.m00042 | SNR8

Description

Na-dependent neurotransmitter transporter; Sodium:neurotransmitter symporter family protein

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Cellular Component

• integral component of plasma membrane (IEA) | GO:0005887
• membrane (IEA) | GO:0016020

Molecular Function

• neurotransmitter:sodium symporter activity (IEA) | GO:0005328

Biological Process

• neurotransmitter transport (IEA) | GO:0006836

Domains

• ( PF00209 ) Sodium:neurotransmitter symporter family

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_16384.1	9.997093137033517e-262
	Description: Sodium:neurotransmitter symporter family protein (589 aa)
WormBase	WBGene00003387	3.000809166761476e-75
	Description: locus:mod-5 Transporter status:Confirmed UniProt:Q9N3C7 protein_id:CCD72993.1
Tetrahymena borealis	EI9_12131.1	3.000809166761476e-75
	Description: hypothetical protein (589 aa)

General Information

No.	Gene Name(s)	Paragraph Text
120	(no standard gene name)	The SNR8 protein is homologous to proteins from the APC Superfamily which is associated with the use of cations as substrate to transport solutes. SNR8 contains one domain (Evalue= 4.0e-77) in the Sodium Neurotransmitter Symporter family that is responsible for the reuptake of neurotransmitters in presynaptic terminals. The closest homologs are in Pseudocohnilembus persalinus, a marine ciliate, Paramecium tetraurelia a unicellular organism that feeds on bacteria, with 51% and 42% identical residues. SNR8 may be an essential protein in terminating the presence and thus the effects of signaling molecules in Tetrahymena thermophila. Paragraph by: Benjamin Wolters, Claremont McKenna College.

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_00678310(coding)
ATGCATGAAAAATTATTCGGGTAAAAAGAGAGACCAAAGCCGAAGCCTTTAACTCTCTTG
ACAAAAAACGAGTAATATAAATTAGAGCATTGGTATGATGAAAATAAAGATGCTCATGAA
AATAGAGGTGAACATAGAGCTGCATTCAATAGATAATTAGATGAAAATCACCACGAAAGA
GATAGATTTAATAGCTATTATGAATATTTAGTTAGCGTTTTAGGTTTTGCTGCTGGTTTT
GGTAGTGTTTGGAGATTCCCTTACCTTATTTTTAAGAACGGAGGAGGTGTCTTTTTGATT
CCTTACTTTATTTTCCTTTTTTTGATAGGATTTCCATCTTTTTACTTTGAAACTGCAATA
GGATAAATATTTCAAAGAGGTCCTCCACTAATTTTTGAAAAAATTCACAAAAAATGGAAA
GGTTTAGGTATCTTCCCAGTATGCGTGAACTTCTCAATGTCAACTTATTATAATCTAATT
TTAGCATATTCAATATACTTTTTATGGAAGAGTTTTACTTATCCTCTACCTTGGAAGTTA
GAAAACTTAGAAGAGAATCAAAAACCTTGGAATAAAGATTATTTTTACAAAAATTTCTTA
AACTCCTCTAGTGGCCTAGATGAATTAGGTGGAATTGTTTGGCCTATCTTTTTCTGCTAT
TTGTTGTCTTAAGTTATTGTTTATTTCTGCATTCAAAAAGGAGTCTCTGTTTCTGGAAAA
ATAGCATTATTTACTGCCACTTCACCTTATATTTTATTATTTATTTTAATGTTGAGAGGA
TTGTTCTTAGAGGGTGCTTTTACTGGGATTTCTTACTTGTTCTCTCCCGACTGGAGCAAG
TTAAGTGATTTATAGGTTTGGGTTGATGCTGCTAATTAAATTATCTTCCAAGTAAGTACA
GGCTGTGGTGTCTTAATCATCTTTGGTAGTTATAGACCAGTTTCATAAGAAATAAAATAA
ACTTCATATATGGTGCCTATGTTAACAGTTTTATGTGGTTTTCTTGCTTCGTTCGTAATT
TTTAGTTTTATGGGCTATATGTCTCACTTAACTGGCTAATCAATCCAAGATATACCATTA
TCTGGTCCAGATCTTGCTTTTGTAGTGTTTCCAGCAGTCTTAACATTAATGCCTTTCTCA
AATTTGCTGTCAATTATTTTCTTTTTGACCATGGTGTTTTTAGGTATAGACACTTAATTT
GCTTTCATGGATGGACTTGCAGGTTCAATTGAAGACGAATTCCATGGTACTGATGCCAAA
ATATTTAATATAACTATCACTTAAAAGCACATTAGAATGGGAATTTGTAGTATTGTATCC
TTATCTGCTTTTCTATACAGTACTTAAGCAGGTTTTTACTATTTAGAATTTATTGATAGC
TACGGCGTTGGAATTAATTTGATTACTGCAGTGTTTATGGAAGTTTACTTTTTTAATTGG
ATGGAGAACTGGGATACTTTAGAAATCAAGATTACCTAATATATTGGAGAACCAACCCCT
TAGATATATAAAACTTTATTAAAATACTCAGTCCCTGTATTTACAGGTCTTTTGGGAGGA
TTAGCTGTGATACTTTAATTACTAAAAATCAACAAATAAGCCTGGTGGGTTAGTATTATT
GGATGGGCTTTTACACTCTATCCATATTATGCTATATATTACTACTATAAAAAATACAAA
GATGAAAAGCCAATCTAAGGAAAAACTAGTTAAGAAAGGGAAGAATAAGGAAATAAAGAA
CTTGAGTAGGAATTAGTTGAATATTGA

>TTHERM_00678310(gene)
ATGCATGAAAAATTATTCGGGTAAAAAGAGAGACCAAAGCCGAAGCCTTTAACTCTCTTG
ACAAAAAACGAGTAATATAAATTAGAGCATTGGTATGATGAAAATAAAGATGCTCATGAA
AATAGAGGTGAACATAGAGCTGCATTCAATAGATAATTAGATGAAAATCACCACGAAAGA
GATAGATTTAATAGCTATTATGAATATTTAGTTAGCGTTTTAGGTTTTGCTGCTGGTTTT
GGTAGTGTTTGGAGATTCCCTTACCTTATTTTTAAGAACGGAGGAGGTGTCTTTTTGATT
CCTTACTTTATTTTCCTTTTTTTGATAGGATTTCCATCTTTTTACTTTGAAACTGCAATA
GGATAAATATTTCAAAGAGGTCCTCCACTAATTTTTGAAAAAGTAAATAAATTTAAATTT
TCTAAGGCATTTTCTTAAATATATTACTCAAAGATGACCTAAAAATTAGCAAGCATCCAT
AAAATGTTATATTTTAATAAATTATTAATTAGATTCACAAAAAATGGAAAGGTTTAGGTA
TCTTCCCAGTATGCGTGAACTTCTCAATGTCAACTTATTATAATCTAATTTTAGCATATT
CAATATACTTTTTATGGAAGAGTTTTACTTATCCTCTACCTTGGAAGTTAGAAAACTTAG
AAGAGAATCAAAAACCTTGGAATAAAGTAAAAAATTATTAAGATTTTTCATAATATGATT
AAGCTTTTTGAATATTTTTCTAAAAGTATGATTGATTTTACATTTATAATAAAAGGATTA
TTTTTACAAAAATTTCTTAAACTCCTCTAGTGGCCTAGATGAATTAGGTGGAATTGTTTG
GCCTATCTTTTTCTGCTATTTGTTGTCTTAAGTTATTGTGTAAATATTTAAAAAATTAAT
TTTATACATAAGCTAACTAATTTTGAAAGTAAAAAAACATTCAATAAATGAATGATATGC
CTGTAAACATATCTGATTATGTTATCTTAAAAGAAATACAAAATTTTAAATTATTTCTGA
TCTAAATCAACAATCAAGTTAGTTGAAAAGCTTGGTTTATAGATTTATTTAATTAACTAT
TTTTAAAGTTTTTAATTATCGATAACTGATTAATTATTTAAGATGATCTCTTCTATAATT
AAATACAATACTATAACTTTTTTATTTGAAATTAAAGCCTTACTTATAATAAAATTAATT
TTAATTTATTTTAAAATTACATTAGTTATTTCTGCATTCAAAAAGGAGTCTCTGTTTCTG
GAAAAATAGCATTATTTACTGCCACTTCACCTTATATTTTATTATTTATTTTAATGTTGA
GAGGATTGTTCTTAGAGGGTGCTTTTACTGGGATTTCTTACTTGTTCTCTCCCGACTGGA
GCAAGTTAAGTGATTTATAGGTTTGGGTTGATGCTGCTAATTAAATTATCTTCCAAGTAA
GTACAGGCTGTGGTGTCTTAATCATCTTTGGTAGTTATAGACCAGTTTCATAAGAAATAA
AATAAACTTCATATATGGTGCCTATGTTAACAGTTTTATGTGGTTTTCTTGCTTCGTTCG
TAATTTTTAGTTTTATGGGCTATATGTCTCACTTAACTGGCTAATCAATCCAAGATATAC
CATTATCTGGTCCAGATCTTGCTTTTGTAGTGTTTCCAGCAGTCTTAACATTAATGCCTT
TCTCAAATTTGCTGTCAATTATTTTCTTTTTGACCATGGTGTTTTTAGGTATTTTAAATG
TTTTTATTTTCAATTTATAAATTTATAATATCATTAACTATAAATAGTTGTGGTAGATAG
ATTATTATTATTTAAAAAATAAATATGTTTTATTGATTAATTAGGTATAGACACTTAATT
TGCTTTCATGGATGGACTTGCAGGTTCAATTGAAGACGAATTCCATGGTACTGATGCCAA
AATATTTAATATAACTATCACTTAAAAGCACATTAGAATGGGAATTTGTAGTATTGTATC
CTTATCTGCTTTTCTATACAGTACTTAAGCAGGTTTTTACTATTTAGAATTTATTGATAG
CTACGGCGTTGGAATTAATTTGATTACTGCAGTGTTTATGGAAGTTTACTTTTTTAATTG
GATGGAGAACTGGGATACTTTAGAAATCAAGATTACCTAATATATTGGAGAACCAACCCC
TTAGATATATAAAACTTTATTAAAATACTCAGTCCCTGTATTTACAGGTCTTTTGGGAGG
ATTAGCTGTGATACTTTAATTACTAAAAATCAACAAATAAGCCTGGTGGGTTAGTATTAT
TGGATGGGCTTTTACACTCTATCCATATTATGCTATATATTACTACTATAAAAAATACAA
AGATGAAAAGCCAATCTAAGGAAAAACTAGTTAAGAAAGGGAAGAATAAGGAAATAAAGA
ACTTGAGTAGGAATTAGTTGAATATTGA

>TTHERM_00678310(protein)
MHEKLFGQKERPKPKPLTLLTKNEQYKLEHWYDENKDAHENRGEHRAAFNRQLDENHHER
DRFNSYYEYLVSVLGFAAGFGSVWRFPYLIFKNGGGVFLIPYFIFLFLIGFPSFYFETAI
GQIFQRGPPLIFEKIHKKWKGLGIFPVCVNFSMSTYYNLILAYSIYFLWKSFTYPLPWKL
ENLEENQKPWNKDYFYKNFLNSSSGLDELGGIVWPIFFCYLLSQVIVYFCIQKGVSVSGK
IALFTATSPYILLFILMLRGLFLEGAFTGISYLFSPDWSKLSDLQVWVDAANQIIFQVST
GCGVLIIFGSYRPVSQEIKQTSYMVPMLTVLCGFLASFVIFSFMGYMSHLTGQSIQDIPL
SGPDLAFVVFPAVLTLMPFSNLLSIIFFLTMVFLGIDTQFAFMDGLAGSIEDEFHGTDAK
IFNITITQKHIRMGICSIVSLSAFLYSTQAGFYYLEFIDSYGVGINLITAVFMEVYFFNW
MENWDTLEIKITQYIGEPTPQIYKTLLKYSVPVFTGLLGGLAVILQLLKINKQAWWVSII
GWAFTLYPYYAIYYYYKKYKDEKPIQGKTSQEREEQGNKELEQELVEY