Identifiers and Description

Gene Model Identifier

TTHERM_00683010

Standard Name

PLA1 (PhosphoLipase A)

Aliases

PreTt16138 | 103.m00129 | 3734.m00041

Description

PLA1 papain family cysteine protease; Lysosomal phospholipase A1; extracellular enzyme that may be secreted into the environment as part of an attack and defense system; Peptidase C1A

Genome Browser (Macronucleus)

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Genome Browser (Micronucleus)

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External Links

Gene Ontology Annotations

Molecular Function

Biological Process

Domains

  • ( PF00112 ) Papain family cysteine protease
  • ( PF08246 ) Cathepsin propeptide inhibitor domain (I29)

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

No Data fetched for Homologs

General Information

No Data fetched for General Information

Associated Literature

  1. Ref:11030577: Hartmann M, Guberman A, Florin-Christensen M, Tiedtke A (2000) Screening for and characterization of phospholipase A1 hypersecretory mutants of Tetrahymena thermophila. Applied microbiology and biotechnology 54(3):390-6
  2. Ref:10063621: Guberman A, Hartmann M, Tiedtke A, Florin-Christensen J, Florin-Christensen M (1999) A method for the preparation of Tetrahymena thermophila phospholipase A1 suitable for large-scale production. Journal of applied microbiology 86(2):226-30

Sequences 

>TTHERM_00683010(coding)
ATGAACAAGACTCTCATCTTAGCTTTAGTTGGTGTTTTGGCTTTAACTGCCACCACCTTG
GTTGCTTTCCACAACCACTCTCACAACATCAGAGTTGACTAAGACCCCGCCACTCTCTTC
AAGCAATTCAAGCAAACTTACAATAAGAAGTATGCTGATCCTACTTTCGAAACCTACAGA
TTCGGTGTCTTCACCCAAAACTTAGAAATCGTCAAGACTGACTCTACTTTCGGTGTCACC
TAATTCATGGACTTAACTCCTGCTGAATTCGCTCAACAATTCCTCACTTTACACGAAAAG
GTTAACAGCACCGAAGTTTACAGAGCTTAAGGTGAAGCTACCGAAGTTGACTGGACTGCC
AAGGGTAAGGTCACCCCTGTTAAGAACTAAGGTTCTTGTGGTTCCTGCTGGGCTTTCTCC
ACCATTGGTGCCGTTGAATCTGCTCTTTTGATTGCTGGTCAAGGTGAATAAAACACTCTT
AACCTTGCTGAATAAGAATTAGTTGACTGTGCTAAGTCCCCCAAGTACGACTCTGAAGGT
TGCAACGGTGGTTGGATGGTTGAAGGTTTCAAGTACATCATCGACAACAAGATCTCCTAA
ACTGCTAACTATCCCTACACTGCTAAGGATGGTAAGTGCAAGGACACCTCTTCCTTCAAG
AAGTTCTCTATTTCTAAGTACGCTGAAATCCCCTAAGGTGACTGCAACTCCCTCAACTCT
GCCTTAGAACAAGGTCCTATCTCCGTTGCTGTTGATGCCACCAACTTCTAATTCTACACT
TCTGGTGTCTTTAAAAACTGCAAGGCCAACCTCAACCACGGTGTCCTCTTAGTTGCCAAC
GTTGACTCTTCTCTCAAGATCAAGAACTCCTGGGGTCCTTCTTGGGGTGAAAAGGGTTTC
ATCAGATTAGCTGCCGGTAACACTTGCGGTGTCTGCAATGCTGCCTCTTACCCTATTGTT
TGA



>TTHERM_00683010(gene)
TGACTCATGAATTTAATAAAGATTTTCAAGTGTTTTCTAATACCGACTAGCTTTATAAAT
TGACTTATTAATCAACGATATAAAAATTATATTAACAAATCAATAAATAAAAAAATAAAT
AAAAACAAAACAAATGAACAAGACTCTCATCTTAGCTTTAGTTGGTGTTTTGGCTTTAAC
TGCCACCACCTTGGTTGCTTTCCACAACCACTCTCACAACATCAGAGTTGACTAAGACCC
CGCCACTCTCTTCAAGCAATTCAAGCAAACTTACAATAAGAAGTATGCTGATCCTACTTT
CGAAACCTACAGATTCGGTGTCTTCACCCAAAACTTAGAAATCGTCAAGACTGACTCTAC
TTTCGGTGTCACCTAATTCATGGACTTAACTCCTGCTGAATTCGCTCAACAATTCCTCAC
TTTACACGAAAAGGTTAACAGCACCGAAGTTTACAGAGCTTAAGGTGAAGCTACCGAAGT
TGACTGGACTGCCAAGGGTAAGGTCACCCCTGTTAAGAACTAAGGTTCTTGTGGTTCCTG
CTGGGCTTTCTCCACCATTGGTGCCGTTGAATCTGCTCTTTTGATTGCTGGTCAAGGTGA
ATAAAACACTCTTAACCTTGCTGAATAAGAATTAGTTGACTGTGCTAAGTCCCCCAAGTA
CGACTCTGAAGGTTGCAACGGTGGTTGGATGGTTGAAGGTTTCAAGTACATCATCGACAA
CAAGATCTCCTAAACTGCTAACTATCCCTACACTGCTAAGGATGGTAAGTGCAAGGACAC
CTCTTCCTTCAAGAAGTTCTCTATTTCTAAGTACGCTGAAATCCCCTAAGGTGACTGCAA
CTCCCTCAACTCTGCCTTAGAACAAGGTCCTATCTCCGTTGCTGTTGATGCCACCAACTT
CTAATTCTACACTTCTGGTGTCTTTAAAAACTGCAAGGCCAACCTCAACCACGGTGTCCT
CTTAGTTGCCAACGTTGACTCTTCTCTCAAGATCAAGAACTCCTGGGGTCCTTCTTGGGG
TGAAAAGGGTTTCATCAGATTAGCTGCCGGTAACACTTGCGGTGTCTGCAATGCTGCCTC
TTACCCTATTGTTTGAAAAAACATAATCCAAATTAAAAAAAATTACTCAAAACTGATAAT
ATAAAAAATTAATTTTCATAATTTTAATGTAAATAAATACCTTTATATTTGACGTTTTGT
ACTCAAAATAAATTAAAGTTAACAAACCATATTTATTTAAT



>TTHERM_00683010(protein)
MNKTLILALVGVLALTATTLVAFHNHSHNIRVDQDPATLFKQFKQTYNKKYADPTFETYR
FGVFTQNLEIVKTDSTFGVTQFMDLTPAEFAQQFLTLHEKVNSTEVYRAQGEATEVDWTA
KGKVTPVKNQGSCGSCWAFSTIGAVESALLIAGQGEQNTLNLAEQELVDCAKSPKYDSEG
CNGGWMVEGFKYIIDNKISQTANYPYTAKDGKCKDTSSFKKFSISKYAEIPQGDCNSLNS
ALEQGPISVAVDATNFQFYTSGVFKNCKANLNHGVLLVANVDSSLKIKNSWGPSWGEKGF
IRLAAGNTCGVCNAASYPIV