Identifiers and Description

Gene Model Identifier

TTHERM_00689900

Standard Name

MPK7 (Mitogen-activated Protein Kinase.)

Aliases

PreTt23186 | 105.m00153 | 3737.m00065 | XP_001026993

Description

cyclin-dependent kinase-like Serine/Threonine kinase family protein; Protein kinase domain containing protein. Sequence similarity to the ERK subfamily of the protein kinase MAPK family (Eisen et al.- 2006). Putative mitogen-activated ERK1/2 subfamily (MAP) kinase (Yildiz&Arslanyolu- 2014)

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Molecular Function

• ATP binding (IEA) | GO:0005524
• protein kinase activity (IEA) | GO:0004672
• protein tyrosine kinase activity (IEA) | GO:0004713

Biological Process

• protein phosphorylation (IEA) | GO:0006468

Domains

• ( PF00069 ) protein kinase domain
• ( PF07714 ) protein tyrosine kinase
• ( PF08194 ) DIM protein

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_16625.2	9.997093137033517e-262
	Description: protein kinase domain-containing protein (833 aa)
DictyBase	DDB_G0286353	2.0006597401342834e-129
	Description: erkA on chromosome: 4 position 4355028 to 4356796
Oxytricha	Contig21734.0.g77	5.998178742922527e-117
	Description: Protein kinase domain
SGD	YBL016W	5.99747839515332e-98
	Description: FUS3 Mitogen-activated serine/threonine protein kinase involved in mating; phosphoactivated by Ste7p; substrates include Ste12p, Far1p, Bni1p, Sst2p; inhibits invasive growth during mating by phosphorylating Tec1p, promoting its degradation
WormBase	WBGene00003401	3.999498296699862e-96
	Description: locus:mpk-1 Mitogen-activated protein kinase mpk-1 status:Partially_confirmed UniProt:P39745 protein_id:CAB60996.1
Stentor Coeruleus	SteCoe_10563	1.1379798735078682e-50
	Description: None

General Information

No Data fetched for General Information

Associated Literature

1. Ref:25286252: Yıldız MT, Arslanyolu M (2014) In silico identification and characterization of the MAPK family members of unicellular model eukaryote Tetrahymena thermophila. European journal of protistology 50(5):538-50
2. Ref:16933976: Eisen JA, Coyne RS, Wu M, Wu D, Thiagarajan M, Wortman JR, Badger JH, Ren Q, Amedeo P, Jones KM, Tallon LJ, Delcher AL, Salzberg SL, Silva JC, Haas BJ, Majoros WH, Farzad M, Carlton JM, Smith RK, Garg J, Pearlman RE, Karrer KM, Sun L, Manning G, Elde NC, Turkewitz AP, Asai DJ, Wilkes DE, Wang Y, Cai H, Collins K, Stewart BA, Lee SR, Wilamowska K, Weinberg Z, Ruzzo WL, Wloga D, Gaertig J, Frankel J, Tsao CC, Gorovsky MA, Keeling PJ, Waller RF, Patron NJ, Cherry JM, Stover NA,

Sequences

>TTHERM_00689900(coding)
ATGCATGAGCTATTGGTTTTGTTCATTTTACAATAAAATTGCTTATTATTGAATAAAGGT
TTATATACTAATGTAATTAAATATATTAGCATAACAAACAAAAGAAAAGAAAAAATTTAT
ATTAAATATTATTTTTAAATAAGATAAAACACAAATAAATAAAAAGCCAGAAGAAAGAAA
AAAATTAATAAAATGCATCCAAATTAAGAGCAAGAAAAGTATGGAATGCAAGCAAATCGC
ATGAACCCAACTGCTGGAAACATGGTAGACTAAAGCAAACAGGATATTATGTATCAGAAT
AATTTTAATGGAGGAAATAATCCTAATGAAATGAACTATTATAGGAATAATTAGCTTCAA
TAGCAGAATTTTATTGAAAATAATAATAACATGTATGCTGCAAATAACATAAATATGGTT
AAAAATTAAATGTTGAATTAACAGTAGGTAATGCCGCCTTAGGGTTAATATATCTAAGAC
CCAAACGCTTAGGTTATTCATTAGTAGTAATAATATGATGATTAAAATTATTATCCTATG
AATGGAGTGAATACTTAACAAAACTAGTAGCATCAGTTTGTGAATATGCAAGGTGATATG
CAAAATCAATAAATATTGAAATAGGGAAATGACTTTTAATAAATTTAATATATGATGGGT
GGTGGAGAAGGTGTATAAATAGATCATCAATATACTATGTACAATTAACTCTAAAATCAT
TAGTTTGACTAAAATTATGGTATGAACAACGATTTAAAGCCTGCTACTGTCAATTCTTAA
TATCCTTAAATAGGGAATCCAAACTATTAGTCAGCCTAGTTTTACTAGAAGCAGTAGCAT
TTAAATACTTTATAGGAATAAAACCAAAAATAGAATAATTAAGAAGTAAAACTCAAACAA
CAACCAAATAGCGACACCGAAGATCCCTATTTTAACTCTATATTCATATTCTAGAATAGG
TTTGATGTTCCCAAGAAATATTAGCTTCTTGTCCCTATAGGCATAGGAGGTTATGGAGTT
GTTGCTAAAGCATTTGATTAAGAGAAATAAGATTTTGTTGCTATAAAAAAAATATTTAAG
CCTTTCTTGAATCCATTAGAGACAAAAAGAATTTTGAGAGAAATTAAAATATTAAAAGCT
TTAGAGCATGATAACATTATTAGTATTAGAGATGTTTTATCACCTGTTCCTAAAGAAAAA
TTAGAAGATATTTATATTATTTCTTAACTTATGGATACTGATTTACATTAAATTATTGCT
TCAGACTAAATTCTTAGTGAAGATCACATATAATTTTTTATTTATTAATTGCTATGCGGT
CTTAAATACATTCATTCAGCAGGAGTATTCCATAGAGATTTAAAACCAGGCAATCTATTA
GTAAACTCAGACTGTGTGTTGAAGATATGTGATTTTGGTCTTGCAAGAACTGTTGATACA
AAGGTTAATGTCTTGGTTCTAATGACAGAATATGTAGCTACGAGATGGTATAGAGCGCCT
GAATTGCTTTTATCTTGGAATAAGTACACAACTGCTATAGATATGTGGGCTGTTGGTTGC
ATTTTTAGCGAATTATACATGAGAAAGCCTTTGTTGCCAGGAGAAAGTTACTTAAATTAG
CTCATTTTAACTCTTAATTTAACAGGTACTCCATCTAAAGAAGATTTAGAAAATATACAA
AGTGATAGAGCCAAATAATTCATTATAAGTTTAGGAAATAAAGCTCCAAAAGATCTTTCT
AAATTAATACCAAATGCCTCACCCTAGGCAATTGATCTTATTAGCAAAATGATAGTCTTT
AATCCAGATAAAAGAATAAGTGCAGAAGAAGCTCTTAAACATCCCTTCTTTGAAGGTATT
CGTGAATCAGAATTTGAAGTAGAAGCAAAAGTTAAATTTGATTTTGATTTTGAAAGAGAA
GATATTACATTAGATGAATTGAAAGATGCAATTTATCAAGAAATGTTAAAGTTCCACCCA
ACTTTTGATGAAAATAACAAGGAAACATACCACATCCCTATTAAAAGAGATTCCGATTTA
TTTACACTTGATTATGATGGTTCTAAAATATATATAGATTATAAGCTAGGATAGAATGAT
TAGCCATAATAGGTAGTTTAAAATATCTAATAAATTAATGAAAAGATGGTTAAAGATATA
ATAGGAGTAGATGGAAATGGTAAAATGATTTAGGACTAGCAATTCATATAGATGCCTTAT
TATAATAACACTATTTTTTCACCTTCATAAGTGGAATAGCAAAATTATTAGCACTATTAA
CAATAGTAGCAATAGCTATATTAGTAGAATTATAACGTATAATAACAGTAGCACTAAACC
GATACATAAAATATTGAATACTAGCAACAATAGTAATAACCACATTTACAGCACTAGGCT
GTGTTTAACCATGAAGGTGGTAATTAATATATGGATATTTAGCAGTAATAATAATAATAA
TAGTAATAGTAGTAATATATGATGAATCAACATTATGTAGATTATAATAACAATAATCAA
GTTTTTATCAATCAGCAATAAGAAATTGATCAAAATGATACATAAATGAGAGAAGAATGA

>TTHERM_00689900(gene)
ATGCATGAGCTATTGGTTTTGTTCATTTTACAATAAAATTGCTTATTATTGAATAAAGGT
TTATATACTAATGTAATTAAATATATTAGCATAACAAACAAAAGAAAAGAAAAAATTTAT
ATTAAATATTATTTTTAAATAAGATAAAACACAAATAAATAAAAAGCCAGAAGAAAGAAA
AAAAGTATAAAAGAACTTATTAAGATATAGTAAAAGATAATACAGTTTTTGATAAAAAAG
TTAATAAAATGCATCCAAATTAAGAGCAAGAAAAGTATGGAATGCAAGCAAATCGCATGA
ACCCAACTGCTGGAAACATGGTAGACTAAAGCAAACAGGATATTATGTATCAGAATAATT
TTAATGGAGGAAATAATCCTAATGAAATGAACTATTATAGGAATAATTAGCTTCAATAGC
AGAATTTTATTGAAAATAGTAATTTAAATTTTGAATTAATTGAATATCAGTTTTAACTAA
ATGATCTATATTCCATTGCACTCAATTATCTTTTGCAAAAAATATTTAATTAAATTCTTT
TTCATTTGATGGAGTATTAATCATTATACTTATTTTATTTTACTAATATTAATCAACTAA
ATTTATTAACAGATAATAACATGTATGCTGCAAATAACATAAATATGGTTAAAAATTAAA
TGTTGAATTAACAGTAGGTAATGCCGCCTTAGGGTTAATATATCTAAGACCCAAACGCTT
AGGTTATTCATTAGTAGTAATAATATGATGATTAAAATTATTATCCTATGAATGGAGTGA
ATACTTAACAAAACTAGTAGCATCAGTTTGTGAATATGCAAGGTGATATGCAAAATCAAT
AAATATTGAAATAGGGAAATGACTTTTAATAAATTTAATATATGATGGGTGGTGGAGAAG
GTGTATAAATAGATCATCAATATACTATGTACAATTAACTCTAAAATCATTAGTTTGACT
AAAATTATGGTATGAACAACGATTTAAAGCCTGCTACTGTCAATTCTTAATATCCTTAAA
TAGGGAATCCAAACTATTAGTCAGCCTAGTTTTACTAGAAGCAGTAGCATTTAAATACTT
TATAGGAATAAAACCAAAAATAGAATAATTAAGAAGTAAAACTCAAACAACAACCAAATA
GCGACACCGAAGATCCCTATTTTAACTCTATATTCATATTCTAGAATAGGTTTGATGTTC
CCAAGAAATATTAGCTTCTTGTCCCTATAGGTAAATGCTTAAGCTTAACAAATAATATAT
AAATAGATAGTTGTTTGTTTATATTATTAATTCATCTTTAAAAAAATAAAAAATATTTCT
TTATGTAATTTAAAAGGCATAGGAGGTTATGGAGTTGTTGCTAAAGCATTTGATTAAGAG
AAATAAGATTTTGTTGCTATAAAAAAAATATTTAAGGTATTTATTTTTTTATTTAGCTTT
TTATGCAGTCAGCAAAACAAATAAGAGATCAAACAAAACTATTCATAAATTTACTTAAAT
GATTTTATATTAAAATGTTATTCATTTAAAATAAATAGCCTTTCTTGAATCCATTAGAGA
CAAAAAGAATTTTGAGAGAAATTAAAATATTAAAAGCTTTAGAGCATGATAACATTATTA
GTATTAGAGATGTTTTATCACCTGTTCCTAAAGAAAAATTAGAAGATATTTATATTATTT
CTTAACTTATGGATACTGATTTACATTAAATTATTGCTTCAGACTAAATTCTTAGTGAAG
ATCACATATAATTTTTTATTTATTAATTGCTATGCGGTCTTAAAGTATTTTAAATTCATT
AATTTATTAGTATGTTAACTAAATTTATTATTTCTTAAAGTACATTCATTCAGCAGGAGT
ATTCCATAGAGATTTAAAACCAGGCAATCTATTAGTAAACTCAGACTGTGTGTTGAAGGT
AAGTTTAGCTCAAATCAATATTTAGGTTAATTTAGATATATTTTTATATAAATAGATATG
TGATTTTGGTCTTGCAAGAACTGTTGATACAAAGGTTAATGTCTTGGTAATTTTATAGAA
GTTTATTTATTTTTTTACTAAAAATTTTTCAATTTTTAGGTTCTAATGACAGAATATGTA
GCTACGAGATGGTATAGAGCGCCTGAATTGCTTTTATCTTGGAATAAGTACACAACTGCT
ATAGATATGTGGGCTGTTGGTTGCATTTTTAGCGAATTATACATGAGAAAGCCTTTGTTG
CCAGGAGAAAGTTACTTAAATTAGCTCATTTTAACTCTTAATTTAACAGGTACTCCATCT
AAAGAAGATTTAGAAAATATACAAAGTGATAGAGCCAAATAATTCATTATAAGTTTAGGA
AATAAAGCTCCAAAAGATCTTTCTAAATTAATACCAAATGCCTCACCCTAGGCAATTGAT
CTTATTAGCAAAATGATAGTCTTTAATCCAGTAACTTTGAATTTGCAATAAAAGCTCCCA
TACAATTTTATTAAAAATTATATTAGGATAAAAGAATAAGTGCAGAAGAAGCTCTTAAAC
ATCCCTTCTTTGAAGGTATTCGTGAATCAGAATTTGAAGTAGAAGCAAAAGTTAAATTTG
ATTTTGATTTTGAAAGAGAAGATATTACATTAGATGAATTGAAAGATGCAATTTATCAAG
AAATGTTAAAGTTCCACCCAACTTTTGATGAAAATAACAAGGAAACATACCACATCCCTA
TTAAAAGAGATTCCGATTTATTTACACTTGATTATGATGGTTCTAAAATATATATAGGTA
ATAAAAATAATAATTGTAAAATTTATTTAATTTTACCTCATTTTTAAAATAGATTATAAG
CTAGGATAGAATGATTAGCCATAATAGGTAGTTTAAAATATCTAATAAATTAATGAAAAG
ATGGTTAAAGATATAATAGGAGTAGATGGAAATGGTAAAATGATTTAGGACTAGCAATTC
ATATAGATGCCTTATTATAATAACACTATTTTTTCACCTTCATAAGTGGAATAGCAAAAT
TATTAGCACTATTAACAATAGTAGCAATAGCTATATTAGTAGAATTATAACGTATAATAA
CAGTAGCACTAAACCGATACATAAAATATTGAATACTAGCAACAATAGTAATAACCACAT
TTACAGCACTAGGCTGTGTTTAACCATGAAGGTGGTAATTAATATATGGATATTTAGCAG
TAATAATAATAATAATAGTAATAGTAGTAATATATGATGAATCAACATTATGTAGATTAT
AATAACAATAATCAAGTTTTTATCAATCAGCAATAAGAAATTGATCAAAATGATACATAA
ATGAGAGAAGAATGA

>TTHERM_00689900(protein)
MHELLVLFILQQNCLLLNKGLYTNVIKYISITNKRKEKIYIKYYFQIRQNTNKQKARRKK
KINKMHPNQEQEKYGMQANRMNPTAGNMVDQSKQDIMYQNNFNGGNNPNEMNYYRNNQLQ
QQNFIENNNNMYAANNINMVKNQMLNQQQVMPPQGQYIQDPNAQVIHQQQQYDDQNYYPM
NGVNTQQNQQHQFVNMQGDMQNQQILKQGNDFQQIQYMMGGGEGVQIDHQYTMYNQLQNH
QFDQNYGMNNDLKPATVNSQYPQIGNPNYQSAQFYQKQQHLNTLQEQNQKQNNQEVKLKQ
QPNSDTEDPYFNSIFIFQNRFDVPKKYQLLVPIGIGGYGVVAKAFDQEKQDFVAIKKIFK
PFLNPLETKRILREIKILKALEHDNIISIRDVLSPVPKEKLEDIYIISQLMDTDLHQIIA
SDQILSEDHIQFFIYQLLCGLKYIHSAGVFHRDLKPGNLLVNSDCVLKICDFGLARTVDT
KVNVLVLMTEYVATRWYRAPELLLSWNKYTTAIDMWAVGCIFSELYMRKPLLPGESYLNQ
LILTLNLTGTPSKEDLENIQSDRAKQFIISLGNKAPKDLSKLIPNASPQAIDLISKMIVF
NPDKRISAEEALKHPFFEGIRESEFEVEAKVKFDFDFEREDITLDELKDAIYQEMLKFHP
TFDENNKETYHIPIKRDSDLFTLDYDGSKIYIDYKLGQNDQPQQVVQNIQQINEKMVKDI
IGVDGNGKMIQDQQFIQMPYYNNTIFSPSQVEQQNYQHYQQQQQQLYQQNYNVQQQQHQT
DTQNIEYQQQQQQPHLQHQAVFNHEGGNQYMDIQQQQQQQQQQQQYMMNQHYVDYNNNNQ
VFINQQQEIDQNDTQMREE