Identifiers and Description

Gene Model Identifier

TTHERM_00691200

Standard Name

TFIIS

Aliases

PreTt02958 | 106.m00098 | 3674.m00011

Description

transcription factor S-II; transcription factor S-II. Interacts with transcription regulator Mediator complex in Tetrahymena.

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Cellular Component

• nucleus (IEA) | GO:0005634

Molecular Function

• DNA binding (IEA) | GO:0003677
• nucleic acid binding (IEA) | GO:0003676
• obsolete transcription regulator activity (IEA) | GO:0030528
• protein binding (IEA) | GO:0005515
• zinc ion binding (IEA) | GO:0008270

Biological Process

• regulation of transcription (IEA) | GO:0045449
• transcription (IEA) | GO:0006350

Domains

• ( PF01096 ) transcription factor S-II (TFIIS)
• ( PF08711 ) Transcription elongation factor S-II protein
• ( TIGR01384 ) transcription factor S
• ( TIGR01385 ) transcription elongation factor S-II
• ( TIGR01784 ) conserved hypothetical protein

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_17617.1	9.997316819378982e-180
	Description: transcription factor S-II (324 aa)
SGD	YDR045C	0.0000029996948234116693
	Description: RPC11 RNA polymerase III subunit C11; mediates pol III RNA cleavage activity and is important for termination of transcription; homologous to TFIIS
WormBase	WBGene00012000	0.00003998524687536623
	Description: Putative transcription elongation factor S-II status:Partially_confirmed UniProt:P52652 protein_id:CAA90943.1
Oxytricha	Contig14486.0.g34	0.0004000184047659232
	Description: Transcription factor S-II (TFIIS), central domain

General Information

No Data fetched for General Information

Associated Literature

1. Ref:31280994: Garg J, Saettone A, Nabeel-Shah S, Cadorin M, Ponce M, Marquez S, Pu S, Greenblatt J, Lambert JP, Pearlman RE, Fillingham J (2019) The Med31 Conserved Component of the Divergent Mediator Complex in Tetrahymena thermophila Participates in Developmental Regulation. Current biology : CB 29(14):2371-2379.e6

Sequences

>TTHERM_00691200(coding)
ATGGATCAACTATACACAGAAGATGAATTGACTGAATTCAAAAACGATTTGAGAAAGTTT
AAGGAAATTGGAAATACTAAAGTTTTGGCCATCGTAAAAAGACTTTTTAATTGCCAAATC
ACAGTATAATAATTATAAAACACTAAAATTGCTTAAACTGTGTAATCTCTCTCTACTATG
TCTTGCTTCGATGAAGATGAAGAAGGACAAGAAGCTAAATAAATATGCTCTTAAATTATT
AACAAATGGAAAAAAATAGTTTAAAATGAAAAAAATAAGCAAAATCCTCAAGCCTCAAGC
TAAAAAGCACCACAATTAACTAAATCAAATTCACAAACTGCTACTTTGCCTAGAAGATAA
TCCTCTGGTTAAGGTTCTACTGAAACATTTTTAACTAATGAGGAACCCTAATACAAGACA
GAATCAAAAACTGATCTTCCTACTTATAAAAGTGATATTCGCTAAAAAGGATTAGAAGCT
ATTAACAAAATTTTTATGAAGGTTAAAGATGATATTAATGCTTCTCCTAGAGAATGGATT
GAATTAATTGTAAATCTTGAAAAGAAAATTTTCTCAAGAAATTCCTAAGTAGTTTACTAT
AAATCTTATATTAAAGAAGTCCTTGGTATGTTCTCTTCTAATGAAGTTACCACTGAGGTT
ATTTCTAAAATGTTAAATAAAGAAATTTCACTTTAGGATGTTGCTGAAGCAAAAACTAGT
GTCTTCTTGACTGATAGATAAAGAGCCTAGCAAAAAAAAGCTGTTGAAGATTAGCTTGCT
ACAAGTGATCCAGATTTTTATAACAATATGCGTAGATAGCGTTTACAAGGTCTAGAAGGT
GAATTATGTAAAGGATGTAAGAAAAAAACAGCTTTCTTAGTAAAAGAATTATAGACTCGT
TCATCAGATGAACCTATGACTCGTTTTATGGAATGCAATAGCTGTGGTAAAAGTTGGAAA
GACTGA

>TTHERM_00691200(gene)
ATGGATCAACTATACACAGAAGATGAATTGACTGAATTCAAAAACGATTTGAGAAAGTTT
AAGGAAATTGGAAATACTAAAGTTTTGGCCATCGTAAAAAGACTTTTTAATTGCCAAATC
ACAGTATAATAATTATAAAACACTAAAATTGCTTAAACTGTGTAATCTCTCTCTACTATG
TCTTGCTTCGATGAAGATGAAGAAGGACAAGAAGCTAAATAAATATGCTCTTAAATTATT
AACAAATGGAAAAAAATAGTTTAAAATGAAAAAAATAAGCAAAATCCTCAAGCCTCAAGC
TAAAAAGCACCACAATTAACTAAATCAAATTCACAAACTGCTACTTTGCCTAGAAGATAA
TCCTCTGGTTAAGGTTCTACTGAAACATTTTTAACTAATGAGGAACCCTAATACAAGACA
GAATCAAAAACTGATCTTCCTACTTATAAAAGTGATATTCGCTAAAAAGGATTAGAAGCT
ATTAACAAAATTTTTATGAAGGTTAAAGATGATATTAATGCTTCTCCTAGAGAATGGATT
GAATTAATTGTAAATCTTGAAAAGAAAATTTTCTCAAGAAATTCCTAAGTAGTTTACTAT
AAATCTTATATTAAAGAAGTCCTTGGTATGTTCTCTTCTAATGAAGTTACCACTGAGGTT
ATTTCTAAAATGTTAAATAAAGAAATTTCACTTTAGGATGTTGCTGAAGCAAAAACTAGT
GTCTTCTTGACTGATAGATAAAGAGCCTAGCAAAAAAAAGCTGTTGAAGATTAGCTTGCT
ACAAGTGATCCAGATTTTTATAACAATATGCGTAGATAGCGTTTACAAGGTCTAGAAGGT
GAATTATGTAAAGGATGTAAGAAAAAAACAGCTTTCTTAGTAAAAGAATTATAGACTCGT
TCATCAGATGAACCTATGACTCGTTTTATGGAATGCAATAGCTGTGGTAAAAGTTGGAAA
GACTGA

>TTHERM_00691200(protein)
MDQLYTEDELTEFKNDLRKFKEIGNTKVLAIVKRLFNCQITVQQLQNTKIAQTVQSLSTM
SCFDEDEEGQEAKQICSQIINKWKKIVQNEKNKQNPQASSQKAPQLTKSNSQTATLPRRQ
SSGQGSTETFLTNEEPQYKTESKTDLPTYKSDIRQKGLEAINKIFMKVKDDINASPREWI
ELIVNLEKKIFSRNSQVVYYKSYIKEVLGMFSSNEVTTEVISKMLNKEISLQDVAEAKTS
VFLTDRQRAQQKKAVEDQLATSDPDFYNNMRRQRLQGLEGELCKGCKKKTAFLVKELQTR
SSDEPMTRFMECNSCGKSWKD