Identifiers and Description

Gene Model Identifier

TTHERM_00704040

Standard Name

AMT1 (Adenine MethylTransferase (AMT) 1 targeting position N-six of Adenine)

Aliases

PreTt20179 | 110.m00152 | MTA1

Description

MT-a70 family protein; MT-A70 family protein; localizes to macronucleus

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Cellular Component

• micronucleus (IDA) | GO:0031040

Molecular Function

• methyltransferase activity (IEA) | GO:0008168

Biological Process

• nucleobase-containing compound metabolic process (IEA) | GO:0006139

Domains

• ( PF01555 ) DNA methylase
• ( PF05063 ) MT-A70

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_15256.1	9.997093137033517e-262
	Description: MT-A70 family protein (374 aa)
WormBase	WBGene00021412	9.997093137033517e-262
	Description: locus:cyp-29A3 status:Partially_confirmed UniProt:Q9N525 protein_id:CCD61789.1
Oxytricha	Contig12701.0.0.g16	8.997297067630326e-99
	Description: MT-A70
SGD	YGL192W	1.0002124404074584e-26
	Description: IME4 Probable mRNA N6-adenosine methyltransferase required for entry into meiosis; transcribed in diploid cells; haploids repress IME4 transcription via production of antisense IME4 transcripts; antisense transcription is repressed in diploids
Stentor Coeruleus	SteCoe_21805	3.1391327920480296e-17
	Description: None

General Information

No Data fetched for General Information

Associated Literature

1. Ref:31722409: Wang Y, Sheng Y, Liu Y, Zhang W, Cheng T, Duan L, Pan B, Qiao Y, Liu Y, Gao S (2019) A distinct class of eukaryotic MT-A70 methyltransferases maintain symmetric DNA N6-adenine methylation at the ApT dinucleotides as an epigenetic mark associated with transcription. Nucleic acids research 47(22):11771-11789

Sequences

>TTHERM_00704040(coding)
ATGAAGAAAGAATAATAATTTTTGATATTCAAGAAAAGTTTAATTATTGCGCAAAAAAGA
AAAGAAATTAATATTAAACAACTAAAATAACAATTTAAAAATTTTTTGTTTGTTTAGATT
TTTTCGATAATTAAATTAAAATTACAAGATATAATTATCAAGTTCAAAATGTCAAAAGCA
GTTAATAAAAAGGGATTGCGTCCCAGAAAGTCAGACTCAATTCTAGATCATATTAAGAAT
AAGTTAGATCAAGAATTCTTAGAGGATAATGAAAATGGTGAATAAAGTGATGAAGATTAC
GATTAAAAGTCTTTAAACAAAGCAAAAAAGCCATACAAAAAGAGATAAACTTAAAATGGA
TCTGAATTAGTTATTTCTCAATAAAAAACAAAAGCAAAAGCATCAGCAAATAATAAAAAA
AGTGCTAAAAATAGCCAGAAATTGGATGAAGAAGAAAAAATTGTTGAGGAAGAAGATTTA
TCTCCTCAAAAGAATGGTGCTGTATCTGAAGATGATTAGCAATAAGAAGCCTCTACATAA
GAGGATGACTACTTAGATAGATTACCTAAATCAAAAAAAGGACTTTAGGGATTATTATAA
GATATTGAAAAGAGAATTCTTCATTATAAATAATTATTTTTCAAAGAATAAAATGAAATA
GCTAATGGAAAAAGGAGTATGGTACCAGATAATTCAATTCCAATTTGCTCAGATGTTACA
AAACTTAATTTCTAAGCTTTAATAGATGCATAAATGAGACACGCTGGTAAGATGTTCGAT
GTTATTATGATGGATCCTCCTTGGTAACTCTCATCCTCTCAACCTTCAAGAGGTGTAGCT
ATTGCTTATGATTCTCTATCAGATGAAAAGATTTAAAACATGCCAATCCAATCTCTATAA
CAAGATGGATTTATTTTTGTTTGGGCAATTAATGCTAAATACAGAGTTACAATAAAAATG
ATTGAGAATTGGGGTTATAAATTAGTTGACGAAATAACTTGGGTAAAAAAGACTGTTAAT
GGTAAAATCGCAAAAGGACATGGATTCTACTTGCAACATGCTAAAGAAAGTTGTTTAATA
GGAGTAAAGGGAGATGTTGACAATGGCAGATTTAAAAAGAACATTGCTAGTGATGTTATT
TTTAGTGAAAGAAGAGGTTAAAGTTAGAAGCCTGAAGAAATTTATCAATATATAAATTAA
CTTTGTCCTAATGGAAATTATTTAGAAATCTTTGCCAGAAGAAATAATTTACATGATAAT
TGGGTTTCAATAGGAAATGAATTATGA

>TTHERM_00704040(gene)
ATGAAGAAAGAATAATAATTTTTGATATTCAAGAAAAGTTTAATTATTGCGCAAAAAAGA
AAAGAAATTAATATTAAACAACTAAAATAACAATTTAAAAATTTTTTGTTTGTTTAGATT
TTTTCGATAATTAAATTAAAATTACAAGATATAATTATCAAGTTCAAAATGTCAAAAGCA
GTTAATAAAAAGGGATTGCGTCCCAGAAAGTCAGACTCAATTCTAGATCATATTAAGAAT
AAGTTAGATCAAGAATTCTTAGAGGATAATGAAAATGGTGAATAAAGTGATGAAGATTAC
GATTAAAAGTCTTTAAACAAAGCAAAAAAGCCATACAAAAAGAGATAAACTTAAAATGGA
TCTGAATTAGTTATTTCTCAATAAAAAACAAAAGCAAAAGCATCAGCAAATAATAAAAAA
AGTGCTAAAAATAGCCAGAAATTGGATGAAGAAGAAAAAATTGTTGAGGAAGAAGATTTA
TCTCCTCAAAAGAATGGTGCTGTATCTGAAGATGATTAGCAATAAGAAGCCTCTACATAA
GAGGATGACTACTTAGATAGATTACCTAAATCAAAAAAAGGACTTTAGGGATTATTATAA
GATATTGAAAAGAGAATTCTTCATTATAAATAATTATTTTTCAAAGAATAAAATGAAATA
GCTAATGGAAAAAGGAGTATGGTACCAGATAATTCAATTCCAATTTGCTCAGATGTTACA
AAACTTAATTTCTAAGCTTTAATAGATGCATAAATGAGACACGCTGGTAAGATGTTCGAT
GTTATTATGATGGATCCTCCTTGGTAACTCTCATCCTCTCAACCTTCAAGAGGTGTAGCT
ATTGCTTATGATTCTCTATCAGATGAAAAGATTTAAAACATGCCAATCCAATCTCTATAA
CAAGATGGATTTATTTTTGTTTGGGCAATTAATGCTAAATACAGGTATATATATATAAGC
ATTAAACAAAGCAATATTTTAAAATTTTTTAATGGAAAAATAGAGTTACAATAAAAATGA
TTGAGAATTGGGGTTATAAATTAGTTGACGAAATAACTTGGGTAAAAAAGACTGTTAATG
GTAAAATCGCAAAAGGACATGGATTCTACTTGCAACATGCTAAAGAAAGTTGTTTAATAG
GAGTAAAGGTAAGAAATTTATTTAAAAAGGTATTTAAAGTTAATAATTATTATTATTTTA
TAATCTCAAGGGAGATGTTGACAATGGCAGATTTAAAAAGAACATTGCTAGTGATGTTAT
TTTTAGTGAAAGAAGAGGTTAAAGTTAGAAGCCTGAAGAAATTTATCAATATATAAATTA
ACTTTGTCCTAATGGTATTATCAAACAAACCAAATATTTATTTGAATTGTATTTTATTTA
TTTTTTTTACATAATAAAAAAAATTAGGAAATTATTTAGAAATCTTTGCCAGAAGAAATA
ATTTACATGATAATTGGGTTTCAATAGGAAATGAATTATGA

>TTHERM_00704040(protein)
MKKEQQFLIFKKSLIIAQKRKEINIKQLKQQFKNFLFVQIFSIIKLKLQDIIIKFKMSKA
VNKKGLRPRKSDSILDHIKNKLDQEFLEDNENGEQSDEDYDQKSLNKAKKPYKKRQTQNG
SELVISQQKTKAKASANNKKSAKNSQKLDEEEKIVEEEDLSPQKNGAVSEDDQQQEASTQ
EDDYLDRLPKSKKGLQGLLQDIEKRILHYKQLFFKEQNEIANGKRSMVPDNSIPICSDVT
KLNFQALIDAQMRHAGKMFDVIMMDPPWQLSSSQPSRGVAIAYDSLSDEKIQNMPIQSLQ
QDGFIFVWAINAKYRVTIKMIENWGYKLVDEITWVKKTVNGKIAKGHGFYLQHAKESCLI
GVKGDVDNGRFKKNIASDVIFSERRGQSQKPEEIYQYINQLCPNGNYLEIFARRNNLHDN
WVSIGNEL