Identifiers and Description

Gene Model Identifier

TTHERM_00705240

Standard Name

HHP1 (H1/HP1-like )

Aliases

PreTt26879 | 111.m00100 | 3744.m00021

Description

HHP1 heterochromatin protein; HP1-like phosphoprotein; implicated in the establishment and/or maintenance of starvation-induced chromatin assembly and gene expression; localized to the macronucleus; contains a chromoshadow domain and a chromodomain; nonessential

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

Gene Ontology Annotations

Cellular Component

• chromatin (IDA) | GO:0000785
• chromatin (IEA) | GO:0000785
• macronucleus (IDA) | GO:0031039
• nucleus (IEA) | GO:0005634

Molecular Function

• chromatin binding (IEA) | GO:0003682
• obsolete transcription activator activity (IMP) | GO:0016563

Biological Process

• cellular response to starvation (IMP) | GO:0009267
• chromatin assembly or disassembly (IMP) | GO:0006333
• chromatin assembly or disassembly (IEA) | GO:0006333
• chromatin silencing (ISS) | GO:0006342
• positive regulation of DNA-templated transcription (IMP) | GO:0045893

Domains

• ( PF00385 ) 'chromo' (CHRromatin Organization MOdifier) domain

Gene Expression Profile

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_17724.1	1.9990449803848145e-49
	Description: heterochromatin-associated protein 1-like protein (178 aa)
WormBase	WBGene00000414	0.000000600201742947405
	Description: locus:cec-1 Chromo domain-containing protein cec-1 status:Confirmed UniProt:P34618 protein_id:CCD66162.1
Oxytricha	Contig9832.0.g37	0.0000007997233352734267
	Description: Chromo (CHRromatin Organisation MOdifier) domain
DictyBase	DDB_G0268134	0.000050024383570459175
	Description: DDB_G0268134 on chromosome: 1 position 1521691 to 1526501

General Information

No Data fetched for General Information

Associated Literature

1. Ref:10207086: Huang H, Smothers JF, Wiley EA, Allis CD (1999) A nonessential HP1-like protein affects starvation-induced assembly of condensed chromatin and gene expression in macronuclei of Tetrahymena thermophila. Molecular and cellular biology 19(5):3624-34
2. Ref:9811850: Huang H, Wiley EA, Lending CR, Allis CD (1998) An HP1-like protein is missing from transcriptionally silent micronuclei of Tetrahymena. Proceedings of the National Academy of Sciences of the United States of America 95(23):13624-9

Sequences

>TTHERM_00705240(coding)
ATGACAAAAGTTTACGAAGTAGAAAATATTATAGGACATAGAAAAAAAGGAAGTTAGATT
GAATACCATATCTAATGGAAAGGCTACTCTCTCAAATAAGCTACTTATGAACCTGCTAAA
AATATTTTAGATAAGAATATGCTTAAAAAATACCAATAAAAGCATTTACTTAGCAATGAT
AAACCTTAGACACCCATTAAGAAATCAATTAAAAAAGGAGCTTCAACTCATTAAACACGT
AAATCTAGCTCAACTACTAAGAGAAGTGTTAAAAAATCAGTTGAAAAAGCATCTAATCCT
AAATCTACTCCTAAATTAGATAAAAAAGCATTAGATCCAGTGAAGGAAATTCATAATTAT
TAAAAGGATGTCAGTAAACTTCTTTTAAAGAGTGATATAACCTCCATATTGCACGTTTTT
AAGGATGATGGAAAATCTCTTTACACAGTCACAATTGGAAAACATCCTAAATAATATTTA
GTATCAAGTAGCTAAATTGCTAAGTATGCTTCTCCCGATCTCATAGTTAGATTCTATGAA
AAGCTAATCCGCTGA

>TTHERM_00705240(gene)
ATGACAAAAGTTTACGAAGTAGAAAATATTATAGGACATAGAAAAAAAGGAAGTTAGATT
GAATACCATATCTAATGGAAAGGCTACTCTCTCAAATAAGCTACTTATGAACCTGCTAAA
AATATTTTAGATAAGAATATGCTTAAAAAATACCAATAGTAATCCCTTACAATTACATCA
ATTAATAAATCAACCATAATTTATTAATTAATATAAGCAAATGGTTGAATAATTTTTTTA
ACTTCAATTTTAATTATATTTAGAAAGCATTTACTTAGCAATGATAAACCTTAGACACCC
ATTAAGAAATCAATTAAAAAAGGAGCTTCAACTCATTAAACACGTAAATCTAGCTCAACT
ACTAAGAGAAGTGTTAAAAAATCAGTTGAAAAAGCATCTAATCCTAAATCTACTCCTAAA
TTAGATAAAAAAGCATTAGATCCAGTGTAAGAAATTTAAATAGAAATGAGCAAACAAACT
GTTATACTTAAAATTAAATTAATTTAAATAAATAGGAAGGAAATTCATAATTATTAAAAG
GATGTCAGTAAACTTCTTTTAAAGAGTGATATAACCTCCATATTGCACGTTTTTAAGGAT
GATGGAAAATCTCTTTACACAGTCACAATTGGAAAACATCCTAAATAATATTTAGTATCA
AGTAGCTAAATTGCTAAGTATGCTTCTCCCGATCTCATAGTTAGATTCTATGAAAAGCTA
ATCCGCTGA

>TTHERM_00705240(protein)
MTKVYEVENIIGHRKKGSQIEYHIQWKGYSLKQATYEPAKNILDKNMLKKYQQKHLLSND
KPQTPIKKSIKKGASTHQTRKSSSTTKRSVKKSVEKASNPKSTPKLDKKALDPVKEIHNY
QKDVSKLLLKSDITSILHVFKDDGKSLYTVTIGKHPKQYLVSSSQIAKYASPDLIVRFYE
KLIR