Identifiers and Description

Gene Model Identifier

TTHERM_00705240

Standard Name

HHP1 (H1/HP1-like )

Aliases

PreTt26879 | 111.m00100 | 3744.m00021

Description

HHP1 heterochromatin protein; HP1-like phosphoprotein; implicated in the establishment and/or maintenance of starvation-induced chromatin assembly and gene expression; localized to the macronucleus; contains a chromoshadow domain and a chromodomain; nonessential; Heterochromatin-associated chromo domain-containing protein

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Cellular Component

• chromatin (IDA) | GO:0000785
• macronucleus (IDA) | GO:0031039

Molecular Function

• obsolete transcription activator activity (IMP) | GO:0016563

Biological Process

• cellular response to starvation (IMP) | GO:0009267
• chromatin assembly or disassembly (IMP) | GO:0006333
• chromatin silencing (ISS) | GO:0006342
• positive regulation of DNA-templated transcription (IMP) | GO:0045893

Domains

• ( PF00385 ) Chromo (CHRromatin Organisation MOdifier) domain

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

No Data fetched for Homologs

General Information

No Data fetched for General Information

Associated Literature

1. Ref:10207086: Huang H, Smothers JF, Wiley EA, Allis CD (1999) A nonessential HP1-like protein affects starvation-induced assembly of condensed chromatin and gene expression in macronuclei of Tetrahymena thermophila. Molecular and cellular biology 19(5):3624-34
2. Ref:9811850: Huang H, Wiley EA, Lending CR, Allis CD (1998) An HP1-like protein is missing from transcriptionally silent micronuclei of Tetrahymena. Proceedings of the National Academy of Sciences of the United States of America 95(23):13624-9

Sequences

>TTHERM_00705240(coding)
ATGACAAAAGTTTACGAAGTAGAAAATATTATAGGACATAGAAAAAAAGGAAGTTAGATT
GAATACCATATCTAATGGAAAGGCTACTCTCTCAAATAAGCTACTTATGAACCTGCTAAA
AATATTTTAGATAAGAATATGCTTAAAAAATACCAATAAAAGCATTTACTTAGCAATGAT
AAACCTTAGACACCCATTAAGAAATCAATTAAAAAAGGAGCTTCAACTCATTAAACACGT
AAATCTAGCTCAACTACTAAGAGAAGTGTTAAAAAATCAGTTGAAAAAGCATCTAATCCT
AAATCTACTCCTAAATTAGATAAAAAAGCATTAGATCCAGTGAAGGAAATTCATAATTAT
TAAAAGGATGTCAGTAAACTTCTTTTAAAGAGTGATATAACCTCCATATTGCACGTTTTT
AAGGATGATGGAAAATCTCTTTACACAGTCACAATTGGAAAACATCCTAAATAATATTTA
GTATCAAGTAGCTAAATTGCTAAGTATGCTTCTCCCGATCTCATAGTTAGATTCTATGAA
AAGCTAATCCGCTGA

>TTHERM_00705240(gene)
GAAATAGTTAATTAAATCAAAAAAAAAAAAGCATCAAATATGACAAAAGTTTACGAAGTA
GAAAATATTATAGGACATAGAAAAAAAGGAAGTTAGATTGAATACCATATCTAATGGAAA
GGCTACTCTCTCAAATAAGCTACTTATGAACCTGCTAAAAATATTTTAGATAAGAATATG
CTTAAAAAATACCAATAAAAGCATTTACTTAGCAATGATAAACCTTAGACACCCATTAAG
AAATCAATTAAAAAAGGAGCTTCAACTCATTAAACACGTAAATCTAGCTCAACTACTAAG
AGAAGTGTTAAAAAATCAGTTGAAAAAGCATCTAATCCTAAATCTACTCCTAAATTAGAT
AAAAAAGCATTAGATCCAGTGAAGGAAATTCATAATTATTAAAAGGATGTCAGTAAACTT
CTTTTAAAGAGTGATATAACCTCCATATTGCACGTTTTTAAGGATGATGGAAAATCTCTT
TACACAGTCACAATTGGAAAACATCCTAAATAATATTTAGTATCAAGTAGCTAAATTGCT
AAGTATGCTTCTCCCGATCTCATAGTTAGATTCTATGAAAAGCTAATCCGCTGATTAGAT
TATATTTATTTATTATTATCATTAAAGTGTCTAGTAATAATTTATGTATTAATATCAATT
AATTCGTTTCCCGCTTATTAAAACAAATTCAATCTTTA

>TTHERM_00705240(protein)
MTKVYEVENIIGHRKKGSQIEYHIQWKGYSLKQATYEPAKNILDKNMLKKYQQKHLLSND
KPQTPIKKSIKKGASTHQTRKSSSTTKRSVKKSVEKASNPKSTPKLDKKALDPVKEIHNY
QKDVSKLLLKSDITSILHVFKDDGKSLYTVTIGKHPKQYLVSSSQIAKYASPDLIVRFYE
KLIR