Identifiers and Description

Gene Model Identifier

TTHERM_00715720

Standard Name

AAG1 (homolog of AlkylAdenine DNA Glycosylase 1)

Aliases

PreTt19046 | 113.m00085 | 3673.m00009

Description

3-methyladenine DNA glycosylase

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Molecular Function

• alkylbase DNA N-glycosylase activity (IEA) | GO:0003905
• DNA binding (IEA) | GO:0003677

Biological Process

• base-excision repair (IEA) | GO:0006284

Domains

• ( PF02245 ) Methylpurine-DNA glycosylase (MPG)
• ( TIGR00567 ) DNA-3-methyladenine glycosylase

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_16844.1	1.9996161777617176e-164
	Description: DNA-3-methyladenine glycosylase (241 aa)
Tetrahymena borealis	EI9_03283.1	1.9996161777617176e-164
	Description: hypothetical protein (587 aa)

General Information

No Data fetched for General Information

Associated Literature

1. Ref:23884606: Gao S, Xiong J, Zhang C, Berquist BR, Yang R, Zhao M, Molascon AJ, Kwiatkowski SY, Yuan D, Qin Z, Wen J, Kapler GM, Andrews PC, Miao W, Liu Y (2013) Impaired replication elongation in Tetrahymena mutants deficient in histone H3 Lys 27 monomethylation. Genes & development 27(15):1662-79

Sequences

>TTHERM_00715720(coding)
ATGTAAAAACAAAAAAGGCCACAAGAAGATATTGAACAGCCAAAGCAAAAATCTATATCA
GATTTTTTTGGAAAAAAGGCTAGCGCAAAGAAGGCTGATGATGATTAACTAAAATAAGTA
CCAGATAGCTTTTATGAAAAAGATGTTGTGACATTAGCATAAGATTTACTAGGAAAGCTG
ATTGTTCATAAAACAAAAGATGGGATAATTGCATGCAGGATAGTAGAAACTGAGGCTTAT
AAGGCTCCAGAAGATAAGGCGTGTCATGCGTATAAAAATAAAAAAACTGAAAAGACAAGC
TCATTTTGGCTTCCAGGAGGTCATGTATATATGTTTACAATTTATAATAATACTTGGTGC
TTTAATGTTGTTGCAGCCACAGCTGAAGAACCAGAAGCTGTTCTTGTTAGAGCTGTAGAG
CCAATTAAAGGACTCCATTTAATTCATAGAAATAGATCCTCACTGAAATCAAATAAAACC
GAAGATTTAGTTAATGGACCTGGAAAACTTACATTGGCTATGGGCATCACCAAAGAAAGA
AATGGATTTGATATGAGAGGAGAAGGAAAAGATTTATTTATAGCAGAATCACCTGAAAAT
TTAAAAAAGTTTGAAATAATTGCAAGCAAAAGAATAAATATAGATTATGCAGAAGAGTGG
ATAGATAAATATTGGAGGTTTACAATCAAAGATAATAAATTTGTTAGTGTTCCCTTGTAA
TTTTGA

>TTHERM_00715720(gene)
ATGTAAAAACAAAAAAGGCCACAAGAAGATATTGAACAGCCAAAGCAAAAATCTATATCA
GATTTTTTTGGAAAAAAGGCTAGCGCAAAGAAGGCTGATGATGATTAACTAAAATAAGTA
CCAGATAGCTTTTATGAAAAAGATGTTGTGACATTAGCATAAGATTTACTAGGAAAGCTG
ATTGTTCATAAAACAAAAGATGGGATAATTGCATGCAGGATAGTAGAAACTGAGGCTTAT
AAGGCTCCAGAAGATAAGGCGTGTCATGCGTATAAAAATAAAAAAACTGAAAAGACAAGC
TCATTTTGGCTTCCAGGAGGTCATGTATATATGTTTACAATTTATAATAATACTTGGTGC
TTTAATGTTGTTGCAGCCACAGCTGAAGAACCAGAAGCTGTTCTTGTTAGGTATTTATTT
AAAATTCTTTTAAAATTTATTATTAACTTATTTATTTTTTATGTAGAGCTGTAGAGCCAA
TTAAAGGACTCCATTTAATTCATAGAAATAGATCCTCACTGAAATCAAATAAAACCGAAG
ATTTAGTTAATGGACCTGGAAAACTTACATTGGCTATGGGCATCACCAAAGAAAGAAATG
GATTTGATATGAGAGGAGAAGGAAAAGATTTATTTATAGCAGAATCACCTGAAAATTTAA
AAAAGTTTGAAATAATTGCAAGCAAAAGAATAAATATAGATTATGCAGAAGAGTGGATAG
ATAAATATTGGAGGTTTACAATCAAAGATAATAAATTTGTTAGTGTTCCCTTGTAATTTT
GA

>TTHERM_00715720(protein)
MQKQKRPQEDIEQPKQKSISDFFGKKASAKKADDDQLKQVPDSFYEKDVVTLAQDLLGKL
IVHKTKDGIIACRIVETEAYKAPEDKACHAYKNKKTEKTSSFWLPGGHVYMFTIYNNTWC
FNVVAATAEEPEAVLVRAVEPIKGLHLIHRNRSSLKSNKTEDLVNGPGKLTLAMGITKER
NGFDMRGEGKDLFIAESPENLKKFEIIASKRINIDYAEEWIDKYWRFTIKDNKFVSVPLQ
F