Identifiers and Description

Gene Model Identifier

TTHERM_00726460

Standard Name

PARP1 (Poly(ADP-Ribosyl) transferase 1)

Aliases

PreTt21911 | 117.m00163

Description

PARP1 poly(ADP-ribose) polymerase family WGR domain protein; WGR domain containing protein; homolog of human PARP1

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Molecular Function

• NAD+-protein poly-ADP-ribosyltransferase activity (IEA) | GO:0003950

Biological Process

• obsolete protein ADP-ribosylation (IEA) | GO:0006471

Domains

• ( PF00644 ) Poly(ADP-ribose) polymerase catalytic domain
• ( PF02877 ) Poly(ADP-ribose) polymerase, regulatory domain
• ( PF05406 ) WGR domain

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_04636.1	9.997093137033517e-262
	Description: WGR domain-containing protein (625 aa)
WormBase	WBGene00000998	9.997093137033517e-262
	Description: locus:dig-1 Mesocentin status:Confirmed UniProt:Q09165 protein_id:CCD72779.1
Oxytricha	Contig12012.0.g59	9.998285701479858e-93
	Description: Poly(ADP-ribose) polymerase catalytic domain
DictyBase	DDB_G0292820	3.0006488705143073e-92
	Description: adprt2 on chromosome: 6 position 2124835 to 2127096
Tetrahymena borealis	EI9_18678.1	3.0006488705143073e-92
	Description: hypothetical protein (606 aa)
WormBase	WBGene00004049	2.9993408039826107e-81
	Description: locus:pme-1 Poly(ADP-ribose) polymerase pme-1 status:Confirmed UniProt:Q9N4H4 protein_id:CCD73512.1
Tetrahymena borealis	EI9_12507.1	2.9993408039826107e-81
	Description: hypothetical protein (1326 aa)
Stentor Coeruleus	SteCoe_27180	2.8946403116483003e-63
	Description: None

General Information

No Data fetched for General Information

Associated Literature

1. Ref:30796450: Ashraf K, Nabeel-Shah S, Garg J, Saettone A, Derynck J, Gingras AC, Lambert JP, Pearlman RE, Fillingham J (2019) Proteomic analysis of histones H2A/H2B and variant Hv1 in Tetrahymena thermophila reveals an ancient network of chaperones. Molecular biology and evolution ( ):

Sequences

>TTHERM_00726460(coding)
ATGTCAGATTAGTCTTCTAATAATTCAGGCAATAATGATTAGATTGGTAATAGTTAGCCT
GTTACAAAAGATGATAAACATAATACTAATGTTGGCTCTAATACTAACATAGATGGAACT
AATCCTATAAACAAATCTACTACTGATAATATAAAAAAACAAATAATTTAAGGGGTAGCT
CCTGTTGATGAATTTTGTCCTTAAAAAGGAGTTGAAGTATACTATGATAAAGATAAAATA
TATTCAGCTAAACTAAATCAAGCAAATATGACAAAAAATAACAACAAATTTTATGTAATT
TAAATACTTAAGGGTAAGATAAACGAATTTTTTGTGTTTAGTCGATGGGGAAGAGTTGGA
TTTTAAGGTTAAAGTTCTTTAAAAGGCCCTTATAATTTATAACGTGCCATTTAAGAATAC
AATTAAAAATTGTTAGAAAAAACAACAGTTAAAGATTATCGTATTCTAGATATGGACTAT
GGACATGATGATATTTTATAAAATTTAGAAGAAAAAATGAAAAAAGATACTGATACATGC
TAATTACCTAAACAAGTTATAAGTCTTATGAGTTTAATTTTTGATATGAATATGTTTAAT
AACTAAATGAAAGAAATTGGATATGATGCAAAAAAGATGCCTCTTGGTAAACTATCTAAA
GATAATATAAACAAGGCTTATGGTATTCTTAAAGATCTTTATGATGAAGTAGAAAAATAA
GACAAGGATATAGTAAAAATAGCAACAATGTGCAATGATTTTTACTCTTACATTCCTCAT
GATTTTGGATTTAAAAAAATGTAGGATCAAATACTTGATAGCACACAAAAAGTTAAAGAA
AAATTAGAAATGATCGATTCTATTTAAAATATATAAATAGCAACTAAAATTTTAGAGGAC
TAATCTTAAGGTTAAAATGGAAATGCAGTTAACTTAATTCAATCCTAATATGAAAAGCTC
AATTGTTCAATTACTCCTTTGAAGGATGAAAAAATTTACCAAACTATAAAAACGTATCTT
GATAATACTCACTCTTATATTCATGATAGATATACATTAGAAATTGAAGATATTTTCGAG
GTAGAAAGATAAGGAGAAAAAGAGAGGTACATGAAATAGCTAAATAACAAAATGCTCCTT
TGGCACGGTTCACGATTGACAAATTATGTTGGAATTTTATCTCAAGGTCTTCGTATTGCT
CCTCCTGAAGCTCCTGCTAATGGTTATATGTTTGGAAAAGGAGTTTATTTTGCTGATATG
TGTAGTAAATCTGCTAATTATTGTTAAGCTAATAAGCTTAACAATACTGGCTTAATGTTT
CTTTGTGAAGTAGCTCTAGGAAATACAAATGACTTAATCTCAGCAGGCTACAATGCTTCT
AAATTACCCTATGGTAAATATAGTGTTAGAGCTTTAGGTTAAATAGCTCCTCCAAAAAAT
TCTTATATAAACATTTATGATGATGTAACAGTTCCTATAGGTAAAGGTCAGGTTAGAGAT
TATAAAAATAGACTTAAAACTCCATTACTGCATAATGAATATATTGTTTATAATGTAAAG
TAAATAATGCTAAAATACCTTTTAAGATTGAAATTTAATTTTAAAAGATGA

>TTHERM_00726460(gene)
ATGTCAGATTAGTCTTCTAATAATTCAGGTAAAACTATTTTTAAAACATTTCAAACTTAA
AATTTAAATATTTTAAAATAAAAATATGAATTCATACTCAAACTCTATTTCAAAAATTCA
AATTTGATTTAGTTAAATAGATAATAAATTTAATTCATATATGACTAGTTTTTATTTTCC
TTTTTTTTCTTGAATATTCTTAAATTTTCTAAAGAATATTTAATTTATCTGTCAAAAATT
ATAATTAAAATATCAAATCTCTCATCAAAAAATACAAATATTAATTTAATATATTACCTA
CCTATTTTGTTTTAATATTGACTCTTACTACAAAAATGTTATTTAATTCATATTATTATA
TATTTCAGGCAATAATGATTAGATTGGTAATAGTTAGCCTGTTACAAAAGATGATAAACA
TAATACTAATGTTGGCTCTAATACTAACATAGATGGAACTAATCCTATAAACAAATCTAC
TACTGATAATATAAAAAAACAAATAATTTAAGGGGTAGCTCCTGTTGATGAATTTTGTCC
TTAAAAAGGAGTTGAAGTATACTATGATAAAGATAAAATATATTCAGCTAAACTAAATCA
AGCAAATATGACAAAAAATAACAACAAATTTTATGTAATTTAAATACTTAAGGGTAAGAT
AAACGAATTTTTTGTGTTTAGTCGATGGGGAAGAGTTGGATTTTAAGGTTAAAGTTCTTT
AAAAGGCCCTTATAATTTATAACGTGCCATTTAAGAATACAATTAAAAATTGTTAGAAAA
AACAACAGTTAAAGATTATCGTATTCTAGATATGGACTATGGACATGATGATATTTTATA
AAATTTAGAAGAAAAAATGAAAAAAGATACTGATACATGCTAATTACCTAAACAAGTTAT
AAGTCTTATGAGTTTAATTTTTGATATGAATATGTTTAATAACTAAATGAAAGAAATTGG
ATATGATGCAAAAAAGATGCCTCTTGGTAAACTATCTAAAGATAATATAAACAAGGCTTA
TGGTATTCTTAAAGATCTTTATGATGAAGTAGAAAAATAAGACAAGGATATAGTAAAAAT
AGCAACAATGTGCAATGATTTTTACTCTTACATTCCTCATGATTTTGGATTTAAAAAAAT
GTAGGATCAAATACTTGATAGCACACAAAAAGTTAAAGAAAAATTAGAAATGATCGATTC
TATTTAAAATATATAAATAGCAACTAAAATTTTAGAGGACTAATCTTAAGGTTAAAATGG
AAATGCAGTTAACTTAATTCAATCCTAATATGAAAAGCTCAATTGTTCAATTACTCCTTT
GAAGGATGAAAAAATTTACCAAACTATAAAAACGTATCTTGATAATACTCACTCTTATAT
TCATGATAGATATACATTAGAAATTGAAGATATTTTCGAGGTAGAAAGATAAGGAGAAAA
AGAGAGGTACATGAAATAGCTAAATAACAAAATGCTCCTTTGGCACGGTTCACGATTGAC
AAATTATGTTGGAATTTTATCTCAAGGTCTTCGTATTGCTCCTCCTGAAGCTCCTGCTAA
TGGTTATATGTTTGGAAAAGGAGTTTATTTTGCTGATATGTGTAGTAAATCTGCTAATTA
TTGTTAAGCTAATAAGCTTAACAATACTGGCTTAATGTTTCTTTGTGAAGTAGCTCTAGG
AAATACAAATGACTTAATCTCAGCAGGCTACAATGCTTCTAAATTACCCTATGGTAAATA
TAGTGTTAGAGCTTTAGGTTAAATAGCTCCTCCAAAAAATTCTTATATAAACATTTATGA
TGATGTAACAGTTCCTATAGGTAAAGGTCAGGTTAGAGATTATAAAAATAGACTTAAAAC
TCCATTACTGCATAATGAATATATTGTTTATAATGTAAAGTAAATAATGCTAAAATACCT
TTTAAGATTGAAATTTAATTTTAAAAGATGA

>TTHERM_00726460(protein)
MSDQSSNNSGNNDQIGNSQPVTKDDKHNTNVGSNTNIDGTNPINKSTTDNIKKQIIQGVA
PVDEFCPQKGVEVYYDKDKIYSAKLNQANMTKNNNKFYVIQILKGKINEFFVFSRWGRVG
FQGQSSLKGPYNLQRAIQEYNQKLLEKTTVKDYRILDMDYGHDDILQNLEEKMKKDTDTC
QLPKQVISLMSLIFDMNMFNNQMKEIGYDAKKMPLGKLSKDNINKAYGILKDLYDEVEKQ
DKDIVKIATMCNDFYSYIPHDFGFKKMQDQILDSTQKVKEKLEMIDSIQNIQIATKILED
QSQGQNGNAVNLIQSQYEKLNCSITPLKDEKIYQTIKTYLDNTHSYIHDRYTLEIEDIFE
VERQGEKERYMKQLNNKMLLWHGSRLTNYVGILSQGLRIAPPEAPANGYMFGKGVYFADM
CSKSANYCQANKLNNTGLMFLCEVALGNTNDLISAGYNASKLPYGKYSVRALGQIAPPKN
SYINIYDDVTVPIGKGQVRDYKNRLKTPLLHNEYIVYNVKQIMLKYLLRLKFNFKR