Identifiers and Description

Gene Model Identifier

TTHERM_00727520

Standard Name

RAB59 (RAB GTPase 59)

Aliases

PreTt07253 | 118.m00081 | 3739.m00004

Description

RAB59 small guanosine triphosphatase family Ras-related in brain (Rab) family protein; Novel Rab family protein; small monomeric GTPase that regulates membrane fusion and fission events

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Cellular Component

• intracellular anatomical structure (IEA) | GO:0005622

Molecular Function

• GTP binding (IEA) | GO:0005525

Biological Process

• small GTPase-mediated signal transduction (IEA) | GO:0007264

Domains

• ( PF00025 ) ADP-ribosylation factor family
• ( PF00071 ) Ras family
• ( PF01926 ) 50S ribosome-binding GTPase
• ( PF08477 ) Ras of Complex, Roc, domain of DAPkinase
• ( TIGR00231 ) small GTP-binding protein domain

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_17907.1	1.000434858898539e-105
	Description: small GTP-binding protein domain-containing protein (185 aa)
DictyBase	DDB_G0277867	3.998097515166115e-39
	Description: rab1B on chromosome: 3 position 743092 to 744234
Oxytricha	Contig15751.0.0.g87	8.003017249547689e-39
	Description: Ras family
SGD	YFL038C	2.00017271388466e-38
	Description: YPT1 Rab family GTPase, involved in the ER-to-Golgi step of the secretory pathway; complex formation with the Rab escort protein Mrs6p is required for prenylation of Ypt1p by protein geranylgeranyltransferase type II (Bet2p-Bet4p)
WormBase	WBGene00004284	1.999002769139511e-37
	Description: locus:rab-35 status:Confirmed UniProt:Q9U2C3 protein_id:CAB57899.1
Stentor Coeruleus	SteCoe_15778	1.5628821893349888e-18
	Description: None

General Information

No Data fetched for General Information

Associated Literature

1. Ref:16933976: Eisen JA, Coyne RS, Wu M, Wu D, Thiagarajan M, Wortman JR, Badger JH, Ren Q, Amedeo P, Jones KM, Tallon LJ, Delcher AL, Salzberg SL, Silva JC, Haas BJ, Majoros WH, Farzad M, Carlton JM, Smith RK, Garg J, Pearlman RE, Karrer KM, Sun L, Manning G, Elde NC, Turkewitz AP, Asai DJ, Wilkes DE, Wang Y, Cai H, Collins K, Stewart BA, Lee SR, Wilamowska K, Weinberg Z, Ruzzo WL, Wloga D, Gaertig J, Frankel J, Tsao CC, Gorovsky MA, Keeling PJ, Waller RF, Patron NJ, Cherry JM, Stover NA,

Sequences

>TTHERM_00727520(coding)
ATGTCTCAAATATCATAGCCATAATAAAATCAAAAAGAATAGTACGACTTCATGGTGAAA
GTAGTTTTAGTAGGTGATGAAGGAGTAGGTAAAACATAAATATCGAGGAGAATAGCAGGT
TTATAATATAACGAAAAGCATACTCCAACTATTGGAGTAGATTTCAAAGTTAAAACTATG
TAAGTAGGCAATAACATTATGAAATTTTAAGTATGGGATACTGCTGGCATACCTAAATAT
CGTGTATCAAATAAAGCTTAATACTCAGGAGCCGCTGCTGTTATAGTTATATTTAGCTTT
AATGATCTATAAAGCTTTGAGAGTGTTGAGAAATGGATATAAGAAATAAATTTTGAAAAT
TAGGATAGCTAAATAGTAAGAGTTTTAGTTGGAAATAAATGTGATTTTTAAAAGGAAGGA
AGATATGCCACTCCTATGGCTGCTGAATAATTAGCAAAGAGAAATAATATGGAATATATT
GAAGTATCTGCTAAAGAAAACCATAACGTTAGAGAGCTTTTCTAATTAGTAGGTTAACAA
ATATATAAAGAATTAATTGATCCTTAATGA

>TTHERM_00727520(gene)
ATGTCTCAAATATCATAGCCATAATAAAATCAAAAAGAATAGTACGACTTCATGGTGAAA
GTAGTTTTAGTAGGTGATGAAGGAGTAGGTAAAACATAAATATCGAGGAGAATAGCAGGT
TTATAATATAACGAAAAGCATACTCCAACTATTGGAGTAGATTTCAAAGTTAAAACTATG
TAAGTAGGCAATAACATTATGAAATTTTAAGTATGGGATACTGCTGGCATACCTAAATAT
CGTGTATCAAATAAAGCTTAATACTCAGGAGCCGCTGCTGTTATAGTTATATTTAGCTTT
AATGATCTATAAAGCTTTGAGAGTGTTGAGAAATGGATATAAGAAATAAATTTTGAAAAT
TAGGATAGCTAAATAGTAAGAGTTTTAGTTGGAAATAAATGTGATTTTTAAAAGGAAGGA
AGATATGCCACTCCTATGGCTGCTGAATAATTAGCAAAGAGAAATAATATGGAATATATT
GAAGTATCTGCTAAAGAAAACCATAACGTTAGAGAGCTTTTCTAATTAGTAGGTTAACAA
ATATATAAAGAATTAATTGATCCTTAATGA

>TTHERM_00727520(protein)
MSQISQPQQNQKEQYDFMVKVVLVGDEGVGKTQISRRIAGLQYNEKHTPTIGVDFKVKTM
QVGNNIMKFQVWDTAGIPKYRVSNKAQYSGAAAVIVIFSFNDLQSFESVEKWIQEINFEN
QDSQIVRVLVGNKCDFQKEGRYATPMAAEQLAKRNNMEYIEVSAKENHNVRELFQLVGQQ
IYKELIDPQ