Identifiers and Description

Gene Model Identifier

TTHERM_00727540

Standard Name

RAB60 (RAB GTPase 60)

Aliases

PreTt07255 | 118.m00083 | 3739.m00006

Description

RAB60 small guanosine triphosphatase family Ras-related in brain (Rab) family protein; Novel Rab family protein; small monomeric GTPase that regulates membrane fusion and fission events

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Cellular Component

• intracellular anatomical structure (IEA) | GO:0005622

Molecular Function

• GTP binding (IEA) | GO:0005525

Biological Process

• small GTPase-mediated signal transduction (IEA) | GO:0007264

Domains

• ( PF00009 ) Elongation factor Tu GTP binding domain
• ( PF00025 ) ADP-ribosylation factor family
• ( PF00071 ) Ras family
• ( PF01926 ) 50S ribosome-binding GTPase
• ( PF08477 ) Ras of Complex, Roc, domain of DAPkinase
• ( TIGR00231 ) small GTP-binding protein domain

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_17908.1	1.9995739544551218e-152
	Description: Ras family protein (251 aa)
DictyBase	DDB_G0280043	5.001636743996964e-56
	Description: rab8A on chromosome: 3 position 3266503 to 3267523
WormBase	WBGene00004272	3.998862432046419e-53
	Description: locus:rab-8 status:Confirmed UniProt:G5EFC1 protein_id:CCD68351.1
Oxytricha	Contig11247.0.g57	2.000555387360374e-52
	Description: Ras family
SGD	YFL038C	1.9998745702418095e-48
	Description: YPT1 Rab family GTPase, involved in the ER-to-Golgi step of the secretory pathway; complex formation with the Rab escort protein Mrs6p is required for prenylation of Ypt1p by protein geranylgeranyltransferase type II (Bet2p-Bet4p)
Stentor Coeruleus	SteCoe_24985	1.185064864233981e-27
	Description: None

General Information

No Data fetched for General Information

Associated Literature

1. Ref:16933976: Eisen JA, Coyne RS, Wu M, Wu D, Thiagarajan M, Wortman JR, Badger JH, Ren Q, Amedeo P, Jones KM, Tallon LJ, Delcher AL, Salzberg SL, Silva JC, Haas BJ, Majoros WH, Farzad M, Carlton JM, Smith RK, Garg J, Pearlman RE, Karrer KM, Sun L, Manning G, Elde NC, Turkewitz AP, Asai DJ, Wilkes DE, Wang Y, Cai H, Collins K, Stewart BA, Lee SR, Wilamowska K, Weinberg Z, Ruzzo WL, Wloga D, Gaertig J, Frankel J, Tsao CC, Gorovsky MA, Keeling PJ, Waller RF, Patron NJ, Cherry JM, Stover NA,

Sequences

>TTHERM_00727540(coding)
ATGAATAAACCAAATTTAAGGCAATTCAAAGATAACGTAGACTACGTTATTAAGATACTT
CTAGTTGGTGATAGTGCAGTAGGAAAGACTAATATTATGCTTAGATATTGTGATCATGGA
TATAAAACAGCTCACATGGTAACAGTAGGAGTCGATTTTAAGATGAAAACTATAAAAGTA
GATTAGAAACAGCTTAAATTAATAATTTGGGATACTGCTGGACAAGAAAAATATTAAGCT
ATGGCTTAAAGTATATATAATGGAGCTCAAGCAGTTATTGTCGTATACAGCATTACTGAT
AGAAATAGTTTCATGAATGTCAGAAATTGGATTAAGTAAATTTCAGAGCATGTTCCAGAT
TAGATTATTATAACCCTAGTAGGAAATAAATGCGATGAAAGCGAAAATTAGAGAAAAGTT
GATAAAGCAGAAGGATAGGCTCTAGCTGATGAATATAAAATTCCTTTCTTTGAATCATCA
GCAAAAGAAAATATTAACATAACATAGTTATTTGAAGAAACAGCTAGATAAATAAAAGAA
AAAATTTTAAATGATATTAATACTGTTGGAGACAGTGCATAAAAAATTAAATTTGACACT
TTACAGGTCGGTTCTCCATCACCATAAAATAATGATAATTTCAAATTAACAGCAGAAAAA
AGCAGATAGTCTGAATAAATGTATACGGAAACAACTCCTTTCGATACAAAAACTCCTTAA
TCATAAAATAATGTTAGTAACTGTCAATGCTGA

>TTHERM_00727540(gene)
ATGAATAAACCAAATTTAAGGCAATTCAAAGATAACGTAGACTACGTTATTAAGATACTT
CTAGTTGGTGATAGTGCAGTAGGAAAGACTAATATTATGCTTAGATATTGTGATCATGGA
TATAAAACAGCTCACATGGTAACAGTAGGAGTCGATTTTAAGATGAAAACTATAAAAGTA
GATTAGAAACAGCTTAAATTAATAATTTGGGATACTGCTGGACAAGAAAAATATTAAGCT
ATGGCTTAAAGTATATATAATGGAGCTCAAGCAGTTATTGTCGTATACAGCATTACTGAT
AGAAATAGTTTCATGAATGTCAGAAATTGGATTAAGTAAATTTCAGAGCATGTTCCAGAT
TAGATTATTATAACCCTAGTAGGAAATAAATGCGATGAAAGCGAAAATTAGAGAAAAGTT
GATAAAGCAGAAGGATAGGCTCTAGCTGATGAATATAAAATTCCTTTCTTTGAATCATCA
GCAAAAGAAAATATTAACATAACATAGTTATTTGAAGAAACAGCTAGATAAATAAAAGAA
AAAATTTTAAATGATATTAATACTGTTGGAGACAGTGCATAAAAAATTAAATTTGACACT
TTACAGGTCGGTTCTCCATCACCATAAAATAATGATAATTTCAAATTAACAGCAGAAAAA
AGCAGATAGTCTGAATAAATGTATACGGAAACAACTCCTTTCGATACAAAAACTCCTTAA
TCATAAAATAATGTTAGTAACTGTCAATGCTGA

>TTHERM_00727540(protein)
MNKPNLRQFKDNVDYVIKILLVGDSAVGKTNIMLRYCDHGYKTAHMVTVGVDFKMKTIKV
DQKQLKLIIWDTAGQEKYQAMAQSIYNGAQAVIVVYSITDRNSFMNVRNWIKQISEHVPD
QIIITLVGNKCDESENQRKVDKAEGQALADEYKIPFFESSAKENINITQLFEETARQIKE
KILNDINTVGDSAQKIKFDTLQVGSPSPQNNDNFKLTAEKSRQSEQMYTETTPFDTKTPQ
SQNNVSNCQC