Identifiers and Description

Gene Model Identifier

TTHERM_00760270

Standard Name

MPK6 (Mitogen-activated Protein Kinase.)

Aliases

PreTt18512 | 125.m00076 | 3672.m00009 | XP_001031643

Description

MAP kinase; Protein kinase domain containing protein. Sequence similarity to the ERK subfamily of the protein kinase MAPK family (Eisen et al.- 2006). Putative mitogen-activated ERK1/2 subfamily (MAP) kinase (Yildiz & Arslanyolu- 2014)

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Molecular Function

• ATP binding (IEA) | GO:0005524
• protein kinase activity (IEA) | GO:0004672
• protein tyrosine kinase activity (IEA) | GO:0004713

Biological Process

• protein phosphorylation (IEA) | GO:0006468

Domains

• ( PF00069 ) Protein kinase domain
• ( PF07714 ) Protein tyrosine and serine/threonine kinase
• ( PF08194 ) DIM protein

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_18967.1	9.997093137033517e-262
	Description: protein kinase domain-containing protein (1451 aa)
Tetrahymena borealis	EI9_20433.1	9.997093137033517e-262
	Description: ankyrin repeat protein (457 aa)
Oxytricha	Contig21734.0.g77	3.0011893800784333e-147
	Description: Protein kinase domain
DictyBase	DDB_G0286353	6.001241942754875e-123
	Description: erkA on chromosome: 4 position 4355028 to 4356796
SGD	YBL016W	9.998496826795377e-105
	Description: FUS3 Mitogen-activated serine/threonine protein kinase involved in mating; phosphoactivated by Ste7p; substrates include Ste12p, Far1p, Bni1p, Sst2p; inhibits invasive growth during mating by phosphorylating Tec1p, promoting its degradation
WormBase	WBGene00003401	1.9998944264638884e-101
	Description: locus:mpk-1 Mitogen-activated protein kinase mpk-1 status:Confirmed UniProt:P39745 protein_id:CAA87057.1
Tetrahymena borealis	EI9_06656.1	1.9998944264638884e-101
	Description: hypothetical protein (673 aa)
Stentor Coeruleus	SteCoe_10563	7.175095973164411e-66
	Description: None

General Information

No Data fetched for General Information

Associated Literature

1. Ref:25286252: Yıldız MT, Arslanyolu M (2014) In silico identification and characterization of the MAPK family members of unicellular model eukaryote Tetrahymena thermophila. European journal of protistology 50(5):538-50
2. Ref:16933976: Eisen JA, Coyne RS, Wu M, Wu D, Thiagarajan M, Wortman JR, Badger JH, Ren Q, Amedeo P, Jones KM, Tallon LJ, Delcher AL, Salzberg SL, Silva JC, Haas BJ, Majoros WH, Farzad M, Carlton JM, Smith RK, Garg J, Pearlman RE, Karrer KM, Sun L, Manning G, Elde NC, Turkewitz AP, Asai DJ, Wilkes DE, Wang Y, Cai H, Collins K, Stewart BA, Lee SR, Wilamowska K, Weinberg Z, Ruzzo WL, Wloga D, Gaertig J, Frankel J, Tsao CC, Gorovsky MA, Keeling PJ, Waller RF, Patron NJ, Cherry JM, Stover NA,

Sequences

>TTHERM_00760270(coding)
ATGGATACAGCTAATTTAGTTGCAAAAGAAGTTGTAGAATACTACTAGCCATACAGACAT
AAAAGTAATTTTACAGTAACTTAAGTGCATGGTTCTGTCTTTAATATAGATGAACGCTAT
AGAATTCTAGAGAAAATTGGACAAGGAGCCTATGGAGTTGTTTCAGCTGCAATTGATTAA
GTAAAAAGAAAAAGTGTTGCAATTAAGAAAATTGAAAAGGCCTTTGATTAAAGAATTTAT
ACCAAGCGTACTCTTCGTGAACTTAAGCTTCTTCGTCTCCTCACTCACGAAAATGTGATA
GGTCTAGAAAGTATTCTCCTTCCTAAGTCAAGAGAAGAGTTCGATGATATCTACTGCGTT
TCAGAGTTAATGGAAACAGATCTTTAATAAATTATTAAGTCAGACTAATAATTGACTTAA
GATCATTGCAAATTCTTTATCTACTAAATTCTTCGTGGGTTAAAATACATTCATTCAGCT
AATGTTATTCATAGAGATCTGAAACCAAGAAACCTTTTGGTTAACTCTAATTGCGATTTA
AAGATTTGCGATTTCGGTCTTGCTAGATCTGTAGCTAACACCAAAAATGATTTAACTGAT
TATGTCACAACTCGTTGGTATAGACCTCCTGAGCTTTTATTGTCATGGACAGATTACACA
TGCGCAATGGATGTTTGGTCTGTTGGTATTATTTTTGCAGAGCTAATAAAAAGAAAGCCC
CTTTTACCAGGCTCAAGCTCATCAGATTAGCTTCTAAGAATATTTGATTTAATAGGTACT
CCATTAGAAAATGAAATATAAATGATACCATATGATGAATATCGTAAATTTATTAGAGAA
TTACCAAAGAGAGAGCCTAAATAGTTTGAAAAAATCTTTTCTAAGGCACCAAAAGAGGCT
TTAGATTTACTTAAAAAAATGTTAACATTTGATTTTAATAAACGTATTACTGTTGAAGAA
GCTCTCAAGCACCCTTACTTGAGTGATCTTCATTTACCTGAAGATGAACCTTCTAGAAGT
GAAGTTCCTTTCTATGAATTTGAATTCGAAATGCACTCCAACTTAACAAGATAATAATAC
AAAGATCTTGTGTATGAAGAAATCCTCCTTTATCACTACCCTGATTTCAAAAAGAAGTAT
TTAGATAAGATTTAAAATAACCAATCTGTTATGTAGCACATATTTGATAATGCTAATAAA
AATATAGTTGATGAAGAATTCTCTTCTGATTAAGATTATTGA

>TTHERM_00760270(gene)
ATGGATACAGCTAATTTAGTTGCAAAAGAAGTTGTAGAATACTACTAGCCATACAGACAT
AAAAGTAATTTTACAGTAACTTAAGTGCATGGTTCTGTCTTTAATATAGATGAACGCTAT
AGAATTCTAGAGAAAAGTAAGTTTAATATAAAAAATGTTAATAAATCATAATTTAATCTA
TTTATATTTTAGTTGGACAAGGAGCCTATGGAGTTGTTTCAGCTGCAATTGATTAAGTAA
AAAGAAAAAGTGTTGCAATTAAGAAAATTGAAAAGGCCTTTGATTAAAGAATTTATACCA
AGCGTACTCTTCGTGAACTTAAGCTTCTTCGTCTCCTCACTCACGAAAATGTAAAAAAAA
TTTCATTTTTTATAAATTTAGTATGTAGTAAGAGTGTTATTATAATTTTTTAAATTTAAT
TGAATAAAATAGGTGATAGGTCTAGAAAGTATTCTCCTTCCTAAGTCAAGAGAAGAGTTC
GATGATATGTAATTAATGCTTTCATTAACAATATTATGATTTTTTAAATTTAAGTTGTAA
TTCAAATAAAATAAAAACAAAAAAAATGAACATTAATTGATAATTGACTTCATGGTAGTC
TTTTAGGAAATAAATTTTAAATTACTATGATAAAATACTAACCTGTTTCATTCTTTATAA
AAAATTTTAAAACTAATTTGCTAAACAAAATAACACGTTTTTAATTAGAAATGAGCCTTA
TTAAAATTTTTAAAAAATAGCTACTGCGTTTCAGAGTTAATGGAAACAGATCTTTAATAA
ATTATTAAGTCAGACTAATAATTGACTTAAGATCATTGCAAATTCTTTATCTACTAAATT
CTTCGTGGGTTAAAATACATTCATTCAGCTAATGTTATTCATAGAGATCTGGTAATAAAT
AAAATCAGTTTTTTTAATTTATTTATAAATGCATTTCACCATTCTTAAAGCAATAAACAA
ACATGTATCTGCAAAATATAGCAAATTTGTTAGTTTAGGAAGATTTATAAAATAGTAAAT
TCATAATTAGGTTTACTCAAGCTTTCAGTCCTTAAATGAATATTAAATTATTAAAAAAAT
ATTTCTAAATCAAAAAAATAGCATGTAGCAAAGAATAATATTTATTTTTTTAAATCTTAA
TAAACTAGAAACCAAGAAACCTTTTGGTTAACTCTAATTGCGATTTAAAGATTTGCGATT
TCGGTCTTGCTAGATCTGTAGCTAACACCAAAAATGATTTAACTGATTATGTCACAACTC
GTTGGTATAGACCTCCTGAGCTTTTATTGTCATGGACAGATTACACATGCGCAAGTATAA
ACTATAAAAATATTAATTTTATCACAAAAATTGAACAAAGTCTTTTATAGGAATTTTTTA
ATTATCATTATCAATTTTTATTTTTTAAAAATTAATTTACTGGATAAAAAATTAGATAAT
TAATTAAGAAATTAAAAGAAATTATCAATATCAGAATTCCTTTTTTACTGTCTAATTTTT
TATTTCTTAATAATTAATTAATTAAATTAGTGGATGTTTGGTCTGTTGGTATTATTTTTG
CAGAGCTAATAAAAAGAAAGCCCCTTTTACCAGGCTCAAGCTCATCAGATTAGCTTCTAA
GAATATTTGATTTAATAGGTACTCCATTAGAAAATGAAATATAAATGATACCATATGATG
AATATCGTAAATTTATTAGAGAATTACCAAAGAGAGAGCCTAAATAGTTTGAAAAAATCT
TTTCTAAGGCACCAAAAGAGGCTTTAGATTTACTTAAAAAAATGTTAACATTTGATTTTA
ATAAACGTATTACTGTTGAAGAAGCTCTCAAGCACCCTTACTTGAGTGATCTTCATTTAC
CTGAAGATGAACCTTCTAGAAGTGAAGTTCCTTTCTATGAATTTGAATTCGAAATGCACT
CCAACTTAACAAGATAATAATACAAAGGTAATTATAATTTTTTATCAATAAATAAATATT
CTTAAAAAAATTAATTGCTTTAAAAACAGATCTTGTGTATGAAGAAATCCTCCTTTATCA
CTACCCTGATTTCAAAAAGAAGTATTTAGATAAGATTTAAAATAACCAATCTGTTATGTA
GCACATATTTGATAATGCTAATAAAAATATAGTAACAAAATATTTTTTAAAAATATAATT
AATTTTTTTCAATTTTAAAGGTTGATGAAGAATTCTCTTCTGATTAAGATTATTGA

>TTHERM_00760270(protein)
MDTANLVAKEVVEYYQPYRHKSNFTVTQVHGSVFNIDERYRILEKIGQGAYGVVSAAIDQ
VKRKSVAIKKIEKAFDQRIYTKRTLRELKLLRLLTHENVIGLESILLPKSREEFDDIYCV
SELMETDLQQIIKSDQQLTQDHCKFFIYQILRGLKYIHSANVIHRDLKPRNLLVNSNCDL
KICDFGLARSVANTKNDLTDYVTTRWYRPPELLLSWTDYTCAMDVWSVGIIFAELIKRKP
LLPGSSSSDQLLRIFDLIGTPLENEIQMIPYDEYRKFIRELPKREPKQFEKIFSKAPKEA
LDLLKKMLTFDFNKRITVEEALKHPYLSDLHLPEDEPSRSEVPFYEFEFEMHSNLTRQQY
KDLVYEEILLYHYPDFKKKYLDKIQNNQSVMQHIFDNANKNIVDEEFSSDQDY