Identifiers and Description

Gene Model Identifier

TTHERM_00766460

Standard Name

Anqa1

Aliases

PreTt03339 | 126.m00137 | 3740.m00061

Description

Anqa1 Tesmin/TSO1-like CXC domain containing protein; Homolog of human Lin54; Tetrahymena contains at least 14 Lin54-like genes, named Anqa1-14 (Nabeel-Shah et al. 2021); Lin-54 family

Genome Browser (Macronucleus)

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Genome Browser (Micronucleus)

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External Links

Gene Ontology Annotations

No Data fetched for Gene Ontology Annotations

Domains

  • ( PF03638 ) Tesmin/TSO1-like CXC domain, cysteine-rich domain

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

No Data fetched for Homologs

General Information

No. Gene Name(s) Paragraph Text
2359 Anqa1 Anqa1 is homolog of human Lin54, subunit of MuvB complex. In Tetrahymena putative MuvB complex contains three conserved subunits including RebL1, Lin9 and Anqa1 (putative orthologs of human Rbbp4/7, Lin9 and Lin54, respectively). Additionally, two divergent subunits Jinn1 and Jinn2 are predicted to be part of this putative MuvB in Tetrahymena. RebL1, Lin9 and Anqa1 reciprocally co-purified with each other during vegetative growth and conjugation. Additionally, IPRA1 and Myb-like proteins interacted with Anqa1 and RebL1. Human MuvB-complex regulates cell-cycle gene expression by forming either DREAM- or B-Myb-MuvB (MMB) complexes. Anqa1 ChIP-seq identified sequence motif that shared similarity with CHR element. Tetrahymena contains at least 14 Lin54-like genes, which were named as Anqa1-14 after the ‘ANQA’ mythological creature thought to appear once in ages (Nabeel-Shah et al. 2021).

Associated Literature

  1. Ref:34086947: Nabeel-Shah S, Garg J, Saettone A, Ashraf K, Lee H, Wahab S, Ahmed N, Fine J, Derynck J, Pu S, Ponce M, Marcon E, Zhang Z, Greenblatt JF, Pearlman RE, Lambert JP, Fillingham J (2021) Functional characterization of RebL1 highlights the evolutionary conservation of oncogenic activities of the RBBP4/7 orthologue in Tetrahymena thermophila. Nucleic acids research ( ):

Sequences 

>TTHERM_00766460(coding)
ATGCAAAGTTCATAAGGTAGAAATTTTATAAGCAAAAATCCAATAGGAGAAGATTTTTTA
TAGCAATTGTAGTTAGATAATCTGCCATAGCAGTTGCTTGAAAAATAAAGGGTTTAAAAT
TAATAATAGTAGTATTAGCAGAATAGCGGTTCTTTAGTTAATAGCAATTTTAGCTCCCAA
TAATAAAAACCTGGTTATACATCGAAAAAGTGTAATTGTAAACAGTCTTAATGCATCAAA
TTGTATTGTGAATGTTATGCTGCTGGAGTTTATTGTAATGGATGCCATTGTGTTAGCTGC
AAGAATAATGATTAATCAGAAGGATGGCGTAATTAAGCAATATAAAATACTCTCGTAAAG
AATCCTACAGCCTTTCTACCTAAAATTAGTTAAAAGCAAGAGACCGCATCAAAAGTTGTT
GATCCTTTAAATTTAGGCAAACATAACAAAGGTTGTGCATGCAAACGTAGTGGCTGTATG
AAAAAGTATTGTGAGTGTTTTTAAGCTGGAGTACCTTGCTCTGAAAATTGCAAATGCACT
GACTGCTAAAATACAGGATTTGTTTCTCATGGAAATTTGCTAAGATAATTTAGAGATGAT
GATTCCTACAATTCTTAAAATTAGATTTTACATAAATTTTTATTAGCCCATAATGAAGAA
CATCTAACCAGTATTTTAGGTGAGAATAATGGAGGAGGAGAATTAGGATTCTATAAAAAG
GGAATACCAATAAAAACTGAATTTATTGAGGAATCTTGCATGAAATTACTATAAATATTA
CACTTACCAGATGAAGATATTTTTAGGCGTAGGGATTAATTAATATTGGAAAAATTCAAT
AAAAATCTTAATCATTCCAATTTAAAAGAAGAGTCTTAAATGGAAAACATCACTTCTTTG
AAAAAAGAAGATAGAATTCTCAAAACTCCTCCATAAAAATCTAAGAGACCAGAAGGGACT
ATGGGAGAAGAAGAGGGATAAAAGAGTGGAGACCACTATAATAAAGATACAAGCTGCGAT
ATTGATTTAGCATGTTAAGATGAAAATATGGATGAAGAAGAAGATATAGTATAGAACAAA
TAAAATCATCTTCATAAAGAAGATGAGGGTGATAATAGTTTAGTTAAAGTTCAAAATGAG
ACATTGCTCAAGGATAGTGAACTTTCATCAATAAATAAGGATAATAATGAATCATAGACA
GAGTCAACAGCTGTAACGTCGTCTATAAATAAATCAAAAAGCTTCTCTTAAAAATCCGAT
TCTAATAACATTTAAAATCTAAATTAAGACAGATAAAAAGAAGGAGATAAGATTAATAGT
GAGGAGCAAGAAGGTTAAATGAAAATAGAAGAAGAAAAGAAAGAAATGATTGAAGAAGAA
GAATAAAAATAGAAAGACAATCTTAATAACGACAAAAACTCAGAAAAGGAAAAATTGTAA
ATAGAATCAGAAGAATAATACGAACAAGAACTTTTGAAACAAAAAAATGGAATTTCCAAT
TAAGAAAGCAGTGGAAATGAAATGGAAATCGAATGCCATTCTTCAGCTTTAAAAAGAAAA
TAGGAGCTCTATGAGATCAGAAGGTCTTTTATTCTGGAAACTTTTATCGATTTACTTAGA
CATGTTGAATAAACTATTTGA



>TTHERM_00766460(gene)
AATACATAAATACATACTTAAACACTCACACATACACAGTTTTATCCTTTTTGATAATAC
ACTCCTTTATAAAAAGTAATTTAAAAGGAAAAATAAAAGAAGAATAACTAACATATTGGC
ACTATTTTCAATAATATATGCAAAGTTCATAAGGTAGAAATTTTATAAGCAAAAATCCAA
TAGGAGAAGATTTTTTATAGCAATTGTAGTTAGATAATCTGCCATAGCAGTTGCTTGAAA
AATAAAGGGTTTAAAATTAATAATAGTAGTATTAGCAGAATAGCGGTTCTTTAGTTAATA
GCAATTTTAGCTCCCAATAATAAAAACCTGGTTATACATCGAAAAAGTGTAATTGTAAAC
AGTCTTAATGCATCAAATTGTATTGTGAATGTTATGCTGCTGGAGTTTATTGTAATGGAT
GCCATTGTGTTAGCTGCAAGAATAATGATTAATCAGAAGGATGGCGTAATTAAGCAATAT
AAAATACTCTCGTAAAGAATCCTACAGCCTTTCTACCTAAAATTAGTTAAAAGCAAGAGA
CCGCATCAAAAGTTGTTGATCCTTTAAATTTAGGCAAACATAACAAAGGTTGTGCATGCA
AACGTAGTGGCTGTATGAAAAAGTATTGTGAGTGTTTTTAAGCTGGAGTACCTTGCTCTG
AAAATTGCAAATGCACTGACTGCTAAAATACAGGATTTGTTTCTCATGGAAATTTGCTAA
GATAATTTAGAGATGATGATTCCTACAATTCTTAAAATTAGATTTTACATAAATTTTTAT
TAGCCCATAATGAAGAACATCTAACCAGTATTTTAGGTGAGAATAATGGAGGAGGAGAAT
TAGGATTCTATAAAAAGGGAATACCAATAAAAACTGAATTTATTGAGGAATCTTGCATGA
AATTACTATAAATATTACACTTACCAGATGAAGATATTTTTAGGCGTAGGGATTAATTAA
TATTGGAAAAATTCAATAAAAATCTTAATCATTCCAATTTAAAAGAAGAGTCTTAAATGG
AAAACATCACTTCTTTGAAAAAAGAAGATAGAATTCTCAAAACTCCTCCATAAAAATCTA
AGAGACCAGAAGGGACTATGGGAGAAGAAGAGGGATAAAAGAGTGGAGACCACTATAATA
AAGATACAAGCTGCGATATTGATTTAGCATGTTAAGATGAAAATATGGATGAAGAAGAAG
ATATAGTATAGAACAAATAAAATCATCTTCATAAAGAAGATGAGGGTGATAATAGTTTAG
TTAAAGTTCAAAATGAGACATTGCTCAAGGATAGTGAACTTTCATCAATAAATAAGGATA
ATAATGAATCATAGACAGAGTCAACAGCTGTAACGTCGTCTATAAATAAATCAAAAAGCT
TCTCTTAAAAATCCGATTCTAATAACATTTAAAATCTAAATTAAGACAGATAAAAAGAAG
GAGATAAGATTAATAGTGAGGAGCAAGAAGGTTAAATGAAAATAGAAGAAGAAAAGAAAG
AAATGATTGAAGAAGAAGAATAAAAATAGAAAGACAATCTTAATAACGACAAAAACTCAG
AAAAGGAAAAATTGTAAATAGAATCAGAAGAATAATACGAACAAGAACTTTTGAAACAAA
AAAATGGAATTTCCAATTAAGAAAGCAGTGGAAATGAAATGGAAATCGAATGCCATTCTT
CAGCTTTAAAAAGAAAATAGGAGCTCTATGAGATCAGAAGGTCTTTTATTCTGGAAACTT
TTATCGATTTACTTAGACATGTTGAATAAACTATTTGAAATGTAGTTTTTGTAGCAAATT
TACAATAATAAAAATCAAATAAAACAAAAAAAAGAATTATCAAAGAAATTAAACAAACAA
ATAAACTAAGAGAAAGACAGACAAACATACAAAAAAACCAACCAACTAACAAACAAACTA
AACTAACTAACTATTACTCTCATACACAAAATGATAATGATTTGTAAATATTACTAAAAT
AAAAACAATTCGTACGAATTTAATAGAAATTCTAATAACAAAAAAAGAGAAAAATATTCT
ATTAAATTCTAAAAAGCAATCCCTAAAATATTCTAATAAAATGAACATTTTTTAATGTTT
CATATTATGGGTAGTTTTTCTGTTTACGTAATTTATGAAAATCATTTTTATTGATTGATT
CATGATTATGATTTAACTATACTCCCCATATTTAATGAATGAATGAATGAATGAATGAAT
GAATGACTTGATTGATACACATTATATTCAGTCAGATAAATAGATAACAAATCAAGGCTG
CATGCCATTCAATTCAACTAGATAGGTAGATAGATAAATAGAAAAATGAAATATTACAAA
TATTATCAATAAAATAAATCAAATATGCTTTGGAGTAGGGAAGGAACTTTCTTTCATTTT
ATATTGAATAACTATAGTTAGATTAAATTAATTTATTTTTTATCTCAATTTGGGATTATA
TTGTAAAATATTAGCTTTAAGATAAATATCACTCACAATCTATAATCTTGTTCATTTGAA
TATGTATATACAATATTTTTTATTTTATCTGTTCATATGTAAATAAAATCCTATATAAAA
TAATTAAATATTAAAT



>TTHERM_00766460(protein)
MQSSQGRNFISKNPIGEDFLQQLQLDNLPQQLLEKQRVQNQQQQYQQNSGSLVNSNFSSQ
QQKPGYTSKKCNCKQSQCIKLYCECYAAGVYCNGCHCVSCKNNDQSEGWRNQAIQNTLVK
NPTAFLPKISQKQETASKVVDPLNLGKHNKGCACKRSGCMKKYCECFQAGVPCSENCKCT
DCQNTGFVSHGNLLRQFRDDDSYNSQNQILHKFLLAHNEEHLTSILGENNGGGELGFYKK
GIPIKTEFIEESCMKLLQILHLPDEDIFRRRDQLILEKFNKNLNHSNLKEESQMENITSL
KKEDRILKTPPQKSKRPEGTMGEEEGQKSGDHYNKDTSCDIDLACQDENMDEEEDIVQNK
QNHLHKEDEGDNSLVKVQNETLLKDSELSSINKDNNESQTESTAVTSSINKSKSFSQKSD
SNNIQNLNQDRQKEGDKINSEEQEGQMKIEEEKKEMIEEEEQKQKDNLNNDKNSEKEKLQ
IESEEQYEQELLKQKNGISNQESSGNEMEIECHSSALKRKQELYEIRRSFILETFIDLLR
HVEQTI