Identifiers and Description

Gene Model Identifier

TTHERM_00773650

Standard Name

PCP5 (PARP Correlated Protein 5)

Aliases

PreTt04456 | 128.m00134 | 3676.m00059 | PZN1

Description

Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger family protein putative. Vertebrate PARPs contain PADR and zinc finger (zf)–PARP domains. None of the Tetrahymena putative PARPs carry these domains. Instead, Tetrahymena has at least six additional proteins carrying PADR1 and zf–PARP domains(Kanwal Ashraf et al., 2019)

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Molecular Function

• DNA binding (IEA) | GO:0003677
• zinc ion binding (IEA) | GO:0008270

Domains

• ( PF00645 ) Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region
• ( PF08063 ) PADR1 domain, zinc ribbon fold

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_07117.1	1.000434858898539e-105
	Description: hypothetical protein (232 aa)
Tetrahymena borealis	EI9_06564.1	1.000434858898539e-105
	Description: ThiF family protein (520 aa)
DictyBase	DDB_G0291872	0.000050024383570459175
	Description: DDB_G0291872 on chromosome: 6 position 855161 to 857960

General Information

No Data fetched for General Information

Associated Literature

1. Ref:30796450: Ashraf K, Nabeel-Shah S, Garg J, Saettone A, Derynck J, Gingras AC, Lambert JP, Pearlman RE, Fillingham J (2019) Proteomic analysis of histones H2A/H2B and variant Hv1 in Tetrahymena thermophila reveals an ancient network of chaperones. Molecular biology and evolution ( ):
2. Ref:23884606: Gao S, Xiong J, Zhang C, Berquist BR, Yang R, Zhao M, Molascon AJ, Kwiatkowski SY, Yuan D, Qin Z, Wen J, Kapler GM, Andrews PC, Miao W, Liu Y (2013) Impaired replication elongation in Tetrahymena mutants deficient in histone H3 Lys 27 monomethylation. Genes & development 27(15):1662-79

Sequences

>TTHERM_00773650(coding)
ATGACAACTAATTTTACTAATTTTTACTACGACTGCTTTTGTGCTGAACTAGCTAAAAGT
GGTAGATCTTAATGTAAAGCATGCTATAATCCTATTGAAAATGATAGCCTAAGAATTGGA
TATAAAATTTATGTTAACGAAGAGCATTCTGTAATAAGTACTAAATGGTATCACCCTAAA
TGTGTAGTTCTACCAGAAAAATTTACAAACTTAAAGGTATGGGATATTGAGGGAATAGAC
GACTTAGAGTCTAAATATCACAAAGAAATAAAAGAATCACTTAAAATCTAATAAGGAAAA
AAAGATTAAAGAGTCTAACATCTCCCAAAAATAACAATTAGAGAGTGTAAACCTACTTCA
AAATTTAACTAATAAAAAACATTCGATAAGCAGTAATGGAATAAGTTTGTTTCTTATAAG
GAAGAGTTTAATAATATGGATTATAAATAACTAAAGTAGTTGTTGATTAAAAATGACTCC
TGCACTTTTGGTGGTAAAAAGTTACTTGCTAAAAGATGTGCTATACTGAAGATGATTGGG
GTTGTGAAACACTGTCCAACATGCGGAGGTAATAGGATAAGATTTTATTTTGCTGATGGC
TAATATTATTGTCCAGGTTATCTAGATGATACTAATTGGGTAGACTGCAAACAATGGTTT
GATGTAGATGAAATTAAAGGATACGATTGGATAGAGTGA

>TTHERM_00773650(gene)
ATGACAACTAATTTTACTAATTTTTACTACGACTGCTTTTGTGCTGAACTAGCTAAAAGT
GGTAGATCTTAATGTAAAGCATGCTATAATCCTATTGAAAATGATAGCCTAAGAATTGGA
TATAAAATTTATGTTAACGAAGAGCATTCTGTAATAAGTACTAAATGGTATCACCCTAAA
TGTGTAGTTCTACCAGAAAAATTTACAAACTTAAAGGTATGGGATATTGAGGGAATAGAC
GACTTAGAGTCTAAATATCACAAAGAAATAAAAGAATCACTTAAAATCTAATAAGGAAAA
AAAGATTAAAGAGTCTAACATCTCCCAAAAATAACAATTAGAGAGTGTAAACCTACTTCA
AAATTTAACTAATAAAAAACATTCGATAAGCAGTAATGGAATAAGTTTGTTTCTTATAAG
GAAGAGTTTAATAATATGGATTATAAATAACTAAAGTAGTTGTTGATTAAAAATGACTCC
TGCACTTTTGGTGGTAAAAAGTTACTTGCTAAAAGATGTGCTATACTGAAGATGATTGGG
GTTGTGAAACACTGTCCAACATGCGGAGGTAATAGGATAAGATTTTATTTTGCTGATGGC
TAATATTATTGTCCAGGTTATCTAGATGATACTAATTGGGTAGACTGCAAACAATGGTTT
GATGTAGATGAAATTAAAGGATACGATTGGATAGAGTGA

>TTHERM_00773650(protein)
MTTNFTNFYYDCFCAELAKSGRSQCKACYNPIENDSLRIGYKIYVNEEHSVISTKWYHPK
CVVLPEKFTNLKVWDIEGIDDLESKYHKEIKESLKIQQGKKDQRVQHLPKITIRECKPTS
KFNQQKTFDKQQWNKFVSYKEEFNNMDYKQLKQLLIKNDSCTFGGKKLLAKRCAILKMIG
VVKHCPTCGGNRIRFYFADGQYYCPGYLDDTNWVDCKQWFDVDEIKGYDWIE