Identifiers and Description

Gene Model Identifier

TTHERM_00780750

Standard Name

RFC4 (Replication factor C subunit 4)

Aliases

PreTt01287 | 130.m00097 | 3738.m00033

Description

RFC4 replication factor C activator 1; Subunit of Replication factor C (RF-C)- which acts as a clamp loader of the proliferating cell nuclear antigen (PCNA)

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Cellular Component

• DNA replication factor C complex (IEA) | GO:0005663

Molecular Function

• ATP binding (IEA) | GO:0005524
• DNA clamp loader activity (IEA) | GO:0003689

Biological Process

• DNA replication (IEA) | GO:0006260

Domains

• ( PF00004 ) ATPase family associated with various cellular activities (AAA)
• ( PF01078 ) Magnesium chelatase, subunit ChlI
• ( PF04548 ) AIG1 family
• ( PF06144 ) DNA polymerase III, delta subunit
• ( PF07726 ) ATPase family associated with various cellular activities (AAA)
• ( PF07728 ) AAA domain (dynein-related subfamily)
• ( PF08542 ) Replication factor C C-terminal domain
• ( PF08718 ) Glycolipid transfer protein (GLTP)
• ( TIGR00678 ) DNA polymerase III, delta' subunit
• ( TIGR02397 ) DNA polymerase III, subunit gamma
• ( TIGR02881 ) stage V sporulation protein K
• ( TIGR02928 ) orc1/cdc6 family replication initiation protein

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_18674.1	9.997093137033517e-262
	Description: ATPase, AAA family protein (324 aa)
Oxytricha	Contig3514.0.g13	6.996820840887259e-117
	Description: Replication factor C C-terminal domain
WormBase	WBGene00004338	5.001313616964319e-114
	Description: locus:rfc-2 status:Confirmed UniProt:O44175 protein_id:CCD63484.1
DictyBase	DDB_G0291868	1.9999366565375063e-113
	Description: rfc2 on chromosome: 6 position 850606 to 851622
SGD	YOL094C	1.9994050701445255e-104
	Description: RFC4 Subunit of heteropentameric Replication factor C (RF-C), which is a DNA binding protein and ATPase that acts as a clamp loader of the proliferating cell nuclear antigen (PCNA) processivity factor for DNA polymerases delta and epsilon
Stentor Coeruleus	SteCoe_4442	6.991989996645917e-56
	Description: None

General Information

No Data fetched for General Information

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_00780750(coding)
ATGGCAAGTAAAGAAATATGGCTTGAGAAGTATCGTCCTCGTACATTAGATGAAGTTTAA
GGTAATGAAGATGCCTTGATCAAGTTAAGAACAATTGCAGAGGAAGGTAACGTCCCAAAT
ATGATATTAGTTGGTCCTCCTGGTATTGGTAAAACTAGTTCAGTACTTTGTTTAGCAAGA
ACACTACTTGCAGATGTATTTGATTCCTGTGCTCTTGAAATGAATGCTTCTGACGAAAGA
GGTATTGATGTTGTCAGAGAAAAAATAAAGAGTTTTGCATAAAAAAAGGTAAATTTAAAG
CCTGGTCTTCATAAAATAATTATTCTTGATGAAGCTGATTCATTAACTGAAGGAGCTTAA
CAGGCTTTAAGAATGATTATTAGTGATTTTGCTGATACTACTAGATTTGTATTAAGTTGT
AATGATAGTTCAAAATTAATTGATGCTATTCAAAGTAGATGTGCTATTTTAAGATTTACT
AAGTTAACTGACGAATAAATATTAAGAAGACTTGAAGAAATTGTAGAAAAAGAAAATATC
AAAATAGATAAGGGAGGTAAAGAAGCTCTACTCTTTACATGTGAAGGAGATATGAGATAA
GCAATTAACAATTTATAAGCTACCTACACTGCTTTCAAACTTGTAAATAAAGAAAATGTC
CTTAAGGTTTGTGATGTCCCAAATGTTGAAGTCCTTTAACAAGTTATTGCAGAATGTGTT
AATGGAAACTTCCATGCTGCTTAAAAGAAACTTTATCCACTATGGGAAGAAGGATATACT
GCTTACGATTTAGTTAACAATTTATATAAACTTATCCAAACTCAAGATATGGATAAATAG
CTTCAATATGAATTTATGAGAGAAATGGCTTTCCTTAAGATGAAAGTTCTTGAAGGCTTG
CCAACATTCTTGCAGATTTCTGGATATCTTGCTAAAATATCTTCTATTGCAAACTCCAAA
AAATGA

>TTHERM_00780750(gene)
ATGGCAAGTAAAGAAATATGGCTTGAGAAGTACTTTTTTAGCATTAATTAGAATTAGCAT
TGAAAATTAATAATTAATTGCTATATTTTAACTGCCATTAAATAAATAATATAATATACT
TATTAGGTATCGTCCTCGTACATTAGATGAAGTTTAAGGTAATGAAGATGCCTTGATCAA
GTTAAGAACAATTGCAGAGGAAGGTAACGTCCCAAATATGATATTAGTTGGTCCTCCTGG
TATTGGTAAAACTAGTTCAGTACTTTGTTTAGCAAGAACACTACTTGCAGATGTATTTGA
TTCCTGTGCTCTTGAAATGAATGCTTCTGACGAAAGAGGTATTGATGTTGTCAGAGAAAA
AATAAAGAGTTTTGCATAAAAAAAGGTAAATTTAAAGCCTGGTCTTCATAAAATAATTAT
TCTTGATGAAGCTGATTCATTAACTGAAGGAGCTTAACAGGTAATTAGGATTATTTTCAT
TTTTTTATTTTCCCTCTCTTTTTTGTTTTTTAAACAAGTGCGCCAAAAGGAAAATGGCTC
TGAGCATTAGAATATTTGATTAATATAAACAAATTAAGAGATAGTTTAATTTTTTTCTTT
ATAATTTATAGGCTTTAAGAATGATTATTAGTGATTTTGCTGATACTACTAGATTTGTAT
TAAGTTGTAATGATAGTTCAAAATTAATTGATGCTATTCAAAGTAGATGTGCTATTTTAA
GATTTACTAAGTTAACTGACGAATAAATATTAAGAAGACTTGAAGAAATTGTAGAAAAAG
AAAATATCAAAATAGATAAGGGAGGTAAAGAAGCTCTACTCTTTACATGTGAAGGAGATA
TGAGATAAGCAATTAACAATTTATAAGCTACCTACACTGCTTTCAAACTTGTAAATAAAG
AAAATGTCCTTAAGGTTTGTGATGTCCCAAATGTTGAAGTCCTTTAACAAGTTATTGCAG
AATGTGTTAATGGAAACTTCCATGCTGCTTAAAAGAAACTTTATCCACTATGGGAAGAAG
GATATACTGCTTACGATTTAGTTAACAATTTATATAAACTTATCCAAACTCAAGATATGG
ATAAATAGCTTCAATATGAATTTATGAGAGAAATGGCTTTCCTTAAGATGAAAGTTCTTG
AAGGCTTGCCAACATTCTTGCAGATTTCTGGATATCTTGCTAAAATATCTTCTATTGCAA
ACTCCAAAAAATGA

>TTHERM_00780750(protein)
MASKEIWLEKYRPRTLDEVQGNEDALIKLRTIAEEGNVPNMILVGPPGIGKTSSVLCLAR
TLLADVFDSCALEMNASDERGIDVVREKIKSFAQKKVNLKPGLHKIIILDEADSLTEGAQ
QALRMIISDFADTTRFVLSCNDSSKLIDAIQSRCAILRFTKLTDEQILRRLEEIVEKENI
KIDKGGKEALLFTCEGDMRQAINNLQATYTAFKLVNKENVLKVCDVPNVEVLQQVIAECV
NGNFHAAQKKLYPLWEEGYTAYDLVNNLYKLIQTQDMDKQLQYEFMREMAFLKMKVLEGL
PTFLQISGYLAKISSIANSKK