Identifiers and Description

Gene Model Identifier

TTHERM_00794110

Standard Name

IDP2  (Isocitrate Dehydrogenase, NADP-specific )

Aliases

PreTt21410 | 134.m00090

Description

NADP-dependent isocitrate dehydrogenase; Cytosolic NADP-specific isocitrate dehydrogenase

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Cellular Component

• integral component of membrane (IEA) | GO:0016021

Molecular Function

• magnesium ion binding (IEA) | GO:0000287
• NAD binding (IEA) | GO:0051287
• oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (IEA) | GO:0016616

Biological Process

• obsolete oxidation-reduction process (IEA) | GO:0055114
• transport (IEA) | GO:0006810

Domains

• ( PF00180 ) Isocitrate/isopropylmalate dehydrogenase
• ( TIGR00127 ) isocitrate dehydrogenase, NADP-dependent
• ( TIGR00175 ) isocitrate dehydrogenase, NAD-dependent
• ( TIGR00183 ) isocitrate dehydrogenase, NADP-dependent
• ( TIGR01712 ) phage N-6-adenine-methyltransferase
• ( TIGR02088 ) isopropylmalate/isohomocitrate dehydrogenases

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Stentor Coeruleus	SteCoe_7744	0
	Description: None
WormBase	WBGene00010317	9.997093137033517e-262
	Description: locus:idh-1 Isocitrate dehydrogenase [NADP] status:Confirmed UniProt:Q21032 protein_id:CAA92778.1
Tetrahymena borealis	EI9_13286.1	9.997093137033517e-262
	Description: dehydrogenase, isocitrate/isopropylmalate family protein (418 aa)
DictyBase	DDB_G0272208	9.997093137033517e-262
	Description: idhC on chromosome: 2 position 1670009 to 1671569
Oxytricha	Contig13323.0.g13	9.997093137033517e-262
	Description: Isocitrate/isopropylmalate dehydrogenase
SGD	YLR174W	9.997093137033517e-262
	Description: IDP2 Cytosolic NADP-specific isocitrate dehydrogenase, catalyzes oxidation of isocitrate to alpha-ketoglutarate; levels are elevated during growth on non-fermentable carbon sources and reduced during growth on glucose
WormBase	WBGene00001760	9.997093137033517e-262
	Description: locus:gst-12 status:Confirmed UniProt:Q93695 protein_id:CAB02288.1

General Information

No Data fetched for General Information

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_00794110(coding)
ATGGCTGAACTCCAAAAGATTAAAGTTACTAACCCCGTTACTGAATTAGACGGTGATGAA
ATGACCAGAGTTATCTGGTAACTCATCAAGGATAAGCTCATTTTACCTTATCTTGACTTG
AACATCAAGTACTTCGATTTAGGTATGGAATACAGAGACTAAACTGACGATAAGGTCACC
CTTGATGCTGCTTAATCTATTGTTGAAACCAAGGTAGGTATCAAGTGTGCCACCATCACC
CCTGATGAAGCCAGAGTCAAGGAATTCAATCTTAAGAAGATGTGGAAATCCCCCAACGGT
ACCATCAGAAATCACATCGGAGGTACTGTCTTCAGAGAACCCATTCTCATGAAGAACGTC
CCTAGACTTGTTCCTGCTTGGACTAAGCCCATCGTTATCGGAAGACACGCTTTCGGTGAT
CAATACAGAGCCACTGACTTCAAGGTTGAAGAAGCTGGTACTTTTGAAATTGTCTTCACC
CCCAAGAATGGTGGTGAAAAGAAGGTCATGAAGGTCTTCGATTACCCTGCTGGTGGTGTT
GGTATGGGTATGTACAACACTGATGAATCTATTACTGAATTCGCCCACTCCAGTTTCAAG
TACGCTCTCGATAGAAAGATGCCCCTTTACTTATCTACCAAGAACACTATCTTGAAGGCT
TACGATGGTAAGTTCAAGGATATCTTCTAAGCTATCTATGACAAGTAATACAAGGAAGAA
TTCACCAAGGCTGGTATCTGGTATGAACACAGACTTATTGACGATATGGTCGCCTATATG
ATGAAGTCTGAAGGTGGTTTCATGTGGGCTTGCAAGAATTACGATGGTGATGTCCAATCT
GACTGTCTTGCTTAAGGTTTTGGTTCTCTTGGTTTAATGACCTCTGTCTTGGTTGGTCCT
AACGATATTATTGAAGCTGAAGCTGCTCACGGTACCGTTACCCGTCACTTCAGATAACAC
CAAAAGGGTCAAGAAACCTCCACTAACTCTATTGCCTCCATCTTCGCTTGGACCTAAGGT
TTATTACACAGAGCTAAGCTTGATAACAACAAGGAATTAGACCTCTTCTGCAAGACCCTT
GAAAGCTCAGTTATTGAAACTGTTGAAACTGGTTTCATGACTAAGGATCTCGCTATTTGC
ATCCAAGGAAGCAATGATGTACCCAGAAGCAAATATCTTACTACCCAAGAATTCATTGAC
AAGGTTGCTGAAACCCTCAGAAAGAACCTCGTTGCTGCTAAATCTAACCTCTGA

>TTHERM_00794110(gene)
ATGGCTGAACTCCAAAAGATTAAAGTTACTAACCCCGTTACTGAATTAGACGGTGATGAA
ATGACCAGAGTTATCTGGTAACTCATCAAGGATAAGCTCATTTTACCTTATCTTGACTTG
AACATCAAGTACTTCGATTTAGGTATGGAATACAGAGACTAAACTGACGATAAGGTCACC
CTTGATGCTGCTTAATCTATTGTTGAAACCAAGGTAGGTATCAAGTGTGCCACCATCACC
CCTGATGAAGCCAGAGTCAAGGAATTCAATCTTAAGAAGATGTGGAAATCCCCCAACGGT
ACCATCAGAAATCACATCGGAGGTACTGTCTTCAGAGAACCCATTCTCATGAAGAACGTC
CCTAGACTTGTTCCTGCTTGGACTAAGCCCATCGTTATCGGTAAATATTTAACTCAATTT
ATTATATATTAAATGGAATAGTTTAATGGCTTCTTTTCTACCCGATAAACTTCTAATTGT
TTATTTAATATTCAGATTTAGATAACAATAATTTTTCAACAGAAGTTGATTAATTGCTTT
AGAATAATTTTGTGAATTTAAAAATATGTGTTATTTACTCTAATAATTACTATTAAATAG
GAAGACACGCTTTCGGTGATCAATACAGAGCCACTGACTTCAAGGTTGAAGAAGCTGGTA
CTTTTGAAATTGTCTTCACCCCCAAGAATGGTGGTGAAAAGAAGGTCATGAAGGTCTTCG
ATTACCCTGCTGGTGGTGTTGGTATGGGTATGTACAACACTGATGAATCTATTACTGAAT
TCGCCCACTCCAGTTTCAAGTACGCTCTCGATAGAAAGATGCCCCTTTACTTATCTACCA
AGAACACTATCTTGAAGGCTTACGATGGTAAGTTCAAGGATATCTTCTAAGCTATCTATG
ACAAGTAATACAAGGAAGAATTCACCAAGGCTGGTATCTGGTATGAACACAGACTTATTG
ACGATATGGTCGCCTATATGATGAAGTCTGAAGGTGGTTTCATGTGGGCTTGCAAGAATT
ACGATGGTGATGTCCAATCTGACTGTCTTGCTTAAGGTAACTAAAACTAATATTCATTTA
TTTAAAAAATAGTTAATTTAAATAAAGAAAGCAAAGATTGCTTAATACAATAGCTAGCTT
AATCAATCAAATAATCAATTTAGATATTAAAGCATAAATCAAGAAACCCTTTTTCTTTTA
TTTTAATTATTTGTTTATTTATTTGCTTACCGATCTTAATTTAAAAAGGAATTATTCATT
CAATTAAAGAATAAATATAGGTTTTAATCAAAAATATAGCTATCAAAAAACAAACAAATA
AATAAAGATTTCTTATTGTTGTATTTCTGATTAAAAGATTGATAAAGATTAATTTTATTT
AATTAATTATCAAATTAAATAAATCAAATCAAATCAAATCAAATAGTTCATACAAAATAA
ATAAATAATAATGATTTTATTCAACAAAAAAATAATTTTGATTCCTAAGCGAATTAACAA
ATAATCTTTGTTTATCCTCTAAAAACTTTAAAATAAACAATCTTTGAGCTCTTCTTTGTC
TTACTACTAATATTCTATTTAGACCTCTTTACTATTAATTAACTAATTATTTTAATTTTA
TAGGTTTTGGTTCTCTTGGTTTAATGACCTCTGTCTTGGTTGGTCCTAACGATATTATTG
AAGCTGAAGCTGCTCACGGTACCGTTACCCGTCACTTCAGATAACACCAAAAGGGTCAAG
AAACCTCCACTAACTCTATTGCCTCCATCTTCGCTTGGACCTAAGGTTTATTACACAGAG
CTAAGCTTGATAACAACAAGGAATTAGACCTCTTCTGCAAGACCCTTGAAAGCTCAGTTA
TTGAAACTGTTGAAACTGGTTTCATGACTAAGGATCTCGCTATTTGCATCCAAGGAAGCA
ATGAGTAAATTCAATTTTTTGCTTTTTGTTAAAAATTAAGTCATATATTAAAATTTAATT
AATTATAATTTTTTAAATATTAATAGTGTACCCAGAAGCAAATATCTTACTACCCAAGAA
TTCATTGACAAGGTTGCTGAAACCCTCAGAAAGAACCTCGTTGCTGCTAAATCTAACCTC
TGA

>TTHERM_00794110(protein)
MAELQKIKVTNPVTELDGDEMTRVIWQLIKDKLILPYLDLNIKYFDLGMEYRDQTDDKVT
LDAAQSIVETKVGIKCATITPDEARVKEFNLKKMWKSPNGTIRNHIGGTVFREPILMKNV
PRLVPAWTKPIVIGRHAFGDQYRATDFKVEEAGTFEIVFTPKNGGEKKVMKVFDYPAGGV
GMGMYNTDESITEFAHSSFKYALDRKMPLYLSTKNTILKAYDGKFKDIFQAIYDKQYKEE
FTKAGIWYEHRLIDDMVAYMMKSEGGFMWACKNYDGDVQSDCLAQGFGSLGLMTSVLVGP
NDIIEAEAAHGTVTRHFRQHQKGQETSTNSIASIFAWTQGLLHRAKLDNNKELDLFCKTL
ESSVIETVETGFMTKDLAICIQGSNDVPRSKYLTTQEFIDKVAETLRKNLVAAKSNL