Identifiers and Description

Gene Model Identifier

TTHERM_00794150

Standard Name

ADF73 (Actin-Depolymerizing Factor 73)

Aliases

PreTt21414 | 134.m00094

Description

ADF73 cofilin/tropomyosin-type actin-binding protein; principle actin-modulating protein involved in membrane deformations (including phagocytosis but not cytokinesis) by severing and depolymerizing F-actin; ADF/Cofilin

Genome Browser (Macronucleus)

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Genome Browser (Micronucleus)

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External Links

Gene Ontology Annotations

Biological Process

Domains

  • ( PF00241 ) Cofilin/tropomyosin-type actin-binding protein
  • ( PF09406 ) Protein of unknown function (DUF2004)

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

No Data fetched for Homologs

General Information

No Data fetched for General Information

Associated Literature

  1. Ref:23729382: Shiozaki N, Nakano K, Kushida Y, Noguchi TQ, Uyeda TQ, Wloga D, Dave D, Vasudevan KK, Gaertig J, Numata O (2013) ADF/cofilin is not essential but is critically important for actin activities during phagocytosis in Tetrahymena thermophila. Eukaryotic cell 12(8):1080-6
  2. Ref:19769938: Shiozaki N, Nakano K, Takaine M, Abe H, Numata O (2009) Usual and unusual biochemical properties of ADF/cofilin-like protein Adf73p in ciliate Tetrahymena thermophila. Biochemical and biophysical research communications 390(1):54-9
  3. Ref:16933976: Eisen JA, Coyne RS, Wu M, Wu D, Thiagarajan M, Wortman JR, Badger JH, Ren Q, Amedeo P, Jones KM, Tallon LJ, Delcher AL, Salzberg SL, Silva JC, Haas BJ, Majoros WH, Farzad M, Carlton JM, Smith RK, Garg J, Pearlman RE, Karrer KM, Sun L, Manning G, Elde NC, Turkewitz AP, Asai DJ, Wilkes DE, Wang Y, Cai H, Collins K, Stewart BA, Lee SR, Wilamowska K, Weinberg Z, Ruzzo WL, Wloga D, Gaertig J, Frankel J, Tsao CC, Gorovsky MA, Keeling PJ, Waller RF, Patron NJ, Cherry JM, Stover NA,

Sequences 

>TTHERM_00794150(coding)
ATGGATATCGGCTTACAAGTTGCTGACGACTGTCTCTAATAATTCCAAGCCATGAAGATG
GAAAAGAAACATCGTTATATTATTTTTCACACTAAGAATAACAAGACCATTGAAATTGAA
AAGATTGGAGCTAGAGATGAAACCTACTAACAATTTGTTGACAGTCTCCCACAAAATGAT
GCTCGTTTCTGCGTTTTTGATTATGATAAGAAATTCGATGATGGCAGAGTCACCTCTAAG
ATTATCTATTTCTTCTGGTGTCCTGATACTGCCCCAGTCAAGGTCAAGATGGTCTCTGCT
ACTACCAATTCATTCTTCTAAAATAAAATCTAAGGTTTCGCTATCAACCTCTAATGCAAT
GATTTAGGTTCTTTCGATACCGAAGAACTCGAAAAGAAGATCCATTGA



>TTHERM_00794150(gene)
AATTAAATCATTCCTTCAAAAAGTAAAAAAAGCAAATAAAGTTTTGAAAAATGGATATCG
GCTTACAAGTTGCTGACGACTGTCTCTAATAATTCCAAGCCATGAAGATGGAAAAGAAAC
ATCGTTATATTATTTTTCACACTAAGAATAACAAGACCATTGAAATTGAAAAGATTGGAG
CTAGAGATGAAACCTACTAACAATTTGTTGACAGTCTCCCACAAAATGATGCTCGTTTCT
GCGTTTTTGATTATGATAAGAAATTCGATGATGGCAGAGTCACCTCTAAGATTATCTATT
TCTTCTGGTGTCCTGATACTGCCCCAGTCAAGGTCAAGATGGTCTCTGCTACTACCAATT
CATTCTTCTAAAATAAAATCTAAGGTTTCGCTATCAACCTCTAATGCAATGATTTAGGTT
CTTTCGATACCGAAGAACTCGAAAAGAAGATCCATTGATTAATTATACTTATATCAATTT
CTATTAAATTTAAAATAGTTATAATTATTTCTATTCTATGTAGTATTTTTTATTTTCTTT
TAAAATAAAAAAATTCACATTTCTTTCTTTTTCAAA



>TTHERM_00794150(protein)
MDIGLQVADDCLQQFQAMKMEKKHRYIIFHTKNNKTIEIEKIGARDETYQQFVDSLPQND
ARFCVFDYDKKFDDGRVTSKIIYFFWCPDTAPVKVKMVSATTNSFFQNKIQGFAINLQCN
DLGSFDTEELEKKIH