Identifiers and Description

Gene Model Identifier

TTHERM_00794230

Standard Name

RAB22 (RAB GTPase 22)

Aliases

PreTt21422 | 134.m00102

Description

RAB22 small guanosine triphosphatase family Ras family protein; Rab V family protein; small monomeric GTPase that regulates membrane fusion and fission events

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Cellular Component

• intracellular anatomical structure (IEA) | GO:0005622

Molecular Function

• GTP binding (IEA) | GO:0005525

Biological Process

• small GTPase-mediated signal transduction (IEA) | GO:0007264

Domains

• ( PF00009 ) Elongation factor Tu GTP binding domain
• ( PF00025 ) ADP-ribosylation factor family
• ( PF00071 ) Ras family
• ( PF01926 ) 50S ribosome-binding GTPase
• ( PF08477 ) Ras of Complex, Roc, domain of DAPkinase
• ( TIGR00152 ) dephospho-CoA kinase
• ( TIGR00231 ) small GTP-binding protein domain

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_13298.1	2.9986702110910746e-96
	Description: small GTP-binding protein domain-containing protein (374 aa)
WormBase	WBGene00004268	6.000481660141652e-51
	Description: locus:rab-5 status:Partially_confirmed UniProt:P91857 protein_id:CAB04205.1
DictyBase	DDB_G0271984	1.0002546821282671e-50
	Description: rab5A on chromosome: 2 position 1113320 to 1114208
SGD	YOR089C	4.000820122464668e-47
	Description: VPS21 Rab family GTPase required for endocytic transport and for sorting of vacuolar hydrolases; localized in endocytic intermediates; detected in mitochondria; geranylgeranylation required for membrane association; mammalian Rab5 homolog
Oxytricha	Contig18785.0.g25	1.9991939848149086e-44
	Description: Ras family
Stentor Coeruleus	SteCoe_5592	1.2995814250075031e-24
	Description: None

General Information

No Data fetched for General Information

Associated Literature

1. Ref:16933976: Eisen JA, Coyne RS, Wu M, Wu D, Thiagarajan M, Wortman JR, Badger JH, Ren Q, Amedeo P, Jones KM, Tallon LJ, Delcher AL, Salzberg SL, Silva JC, Haas BJ, Majoros WH, Farzad M, Carlton JM, Smith RK, Garg J, Pearlman RE, Karrer KM, Sun L, Manning G, Elde NC, Turkewitz AP, Asai DJ, Wilkes DE, Wang Y, Cai H, Collins K, Stewart BA, Lee SR, Wilamowska K, Weinberg Z, Ruzzo WL, Wloga D, Gaertig J, Frankel J, Tsao CC, Gorovsky MA, Keeling PJ, Waller RF, Patron NJ, Cherry JM, Stover NA,

Sequences

>TTHERM_00794230(coding)
ATGTCAAAAGCAAGAGATATCAAGGTTGTCATTTTAGGTGATGCAGGTGTTGGAAAAACA
AGTATCTTGAATAGATTCTCAAACAAAGGTTTTGATGAAAACTCTTAAACAACTTTGGGA
GCTTCATTTATCCCAAAAGTATTGACCAGGGGTGATAAAACCTACAAATTTTAGATTTGG
GATACTGCCGGTTAAGAAAAATACAGATCATTGGCCCCTCTTTATTATAGAGATACTCAT
GCAGCTTTGATTGTTTATGATATCACCAATAGGGCCTCCTTTGATGTATTAAAAAAATGG
GTTCAAGAACTTAGAGAACATGGTCCTGCTAATATCACCATTGCAGTAGTTGGTAACAAA
GTTGATCTTATTGATAGGGAAGATGTTAAATACGATGAAGCTAAATAGTACGCAAATGAA
TTAAATGCCATCTTTTAATACACAAGTGCTAAGGAAAACCAAAATATTGAGAGTTTATTT
ATTTAAATTGCTGAGAAAGAAGAATAAAAAGATATTAATCCAACAAAGCCATAATCAAAT
AAAGGATTTTAAAATTAGGTTTAAAGACCATAGGGAGGAGGCTGCAATTGTTGA

>TTHERM_00794230(gene)
ATGTCAAAAGCAAGAGATATCAAGGTTGTCATTTTAGGTGATGCAGGTAATTATCATCAA
TTACGACATATTTTTAAATAGCAGGATTAAAAGCTTATAATTAATTTGGAATTATATTGT
CATCATTTTTCATTATTTGATTTTGCACTATTAAATATACACAAATATAAATGTGCAATT
TATAAAAAATAAGTTGAATGAATCTGCTTAATGATTTACTATGTTAAAGTTTATTATGTT
ATTTCTTTAAAAAAGGTGTTGGAAAAACAAGTATCTTGAATAGATTCTCAAACAAAGGTT
TTGATGAAAACTCTTAAACAACTTTGGGAGCTTCATTTATCCCAAAAGTATTGACCAGGG
GTGATAAAACCTACAAATTTTAGGTATTAAATAAATATAATATTTTAGATCTTTAATGAA
AGCACCAATTTTAATTTTACGATTATCAGAATGAAAATTTTTAATCAATAATACTTATTT
CTTTTAGATTTGGGATACTGCCGGTTAAGAAAAATACAGATCATTGGCCCCTCTTTATTA
TAGAGGTAACAATTAATTATTAAGCCAAATAAAAGAATTTGAGTTCTATTTTTTATACAT
TTTAAAGATACTCATGCAGCTTTGATTGTTTATGATATCACCAATAGGGCCTCCTTTGAT
GTATTAAAAAAATGGGTTCAAGAACTTAGAGAACATGGTCCTGCTAATATCAGTAATTTA
TTTATCTATTTTATTTTAGCGAATTCATAAAATTAATTTCTCAAGTACCACAAAGAAAAA
AATATGTCTAATTCATATAATTCATAGATAACTTTGTTTTAAACTCATTTAAAGAGATAA
ATATTTGGAATAGCTTTTTATTAATTAATTTTTGAAAATAATGATATTGGTTTTTAATAA
ATAGCCATTGCAGTAGTTGGTAACAAAGTTGATCTTATTGATAGGGAAGATGTTAAATAC
GATGAAGCTAAATAGTACGCAAATGTAAAAAACCAAATTCTACAATTTATAATAGCTTAT
TGATTTTTTATCAAACATAATATCTATCAATTTAAAAATATTCCCATAAATTATTTAATA
GGAATTAAATGCCATCTTTTAATACACAAGTGCTAAGGAAAACCAAAATATTGAGGTAAA
CAATATTCTAAATAATAATTAGAATATATTCTATAAAACATCAAAAATAAATTTAAGTGA
TTAATACTTTTTTAATTAAAATTATAATAGAGTTTATTTATTTAAATTGCTGAGAAAGAA
GAATAAAAAGATATTAATCCAACAAAGCCATAATCAAATAAAGGATTTTAAAATTAGGTT
TAAAGACCATAGGGAGGAGGCTGCAATTGTTGA

>TTHERM_00794230(protein)
MSKARDIKVVILGDAGVGKTSILNRFSNKGFDENSQTTLGASFIPKVLTRGDKTYKFQIW
DTAGQEKYRSLAPLYYRDTHAALIVYDITNRASFDVLKKWVQELREHGPANITIAVVGNK
VDLIDREDVKYDEAKQYANELNAIFQYTSAKENQNIESLFIQIAEKEEQKDINPTKPQSN
KGFQNQVQRPQGGGCNC