Identifiers and Description

Gene Model Identifier

TTHERM_00812950

Standard Name

SMC2 (structural maintenance of chromosomes)

Aliases

PreTt30001 | 138.m00121

Description

SMC2 structural maintenance of chromosomes protein; SMC family- C-terminal domain containing protein- condensin subunit- required for division of MIC and MAC.

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

Gene Ontology Annotations

Cellular Component

• chromosome (IEA) | GO:0005694
• membrane (IEA) | GO:0016020

Molecular Function

• ATP binding (IEA) | GO:0005524
• protein binding (IEA) | GO:0005515

Biological Process

• chromosome organization (IEA) | GO:0051276

Domains

• ( PF00005 ) ABC transporter, ATP-binding protein
• ( PF00435 ) Spectrin repeat
• ( PF00769 ) Ezrin/radixin/moesin family
• ( PF01576 ) Myosin tail
• ( PF02370 ) M protein repeat
• ( PF02463 ) RecF/RecN/SMC N terminal domain
• ( PF04508 ) Viral A-type inclusion protein repeat
• ( PF06470 ) SMC proteins Flexible Hinge Domain
• ( PF06696 ) Streptococcal surface antigen repeat
• ( PF06975 ) Protein of unknown function (DUF1299)
• ( PF08946 ) Osmosensory transporter coiled coil
• ( TIGR00634 ) DNA repair protein RecN
• ( TIGR00650 ) GTP-binding conserved hypothetical protein
• ( TIGR02168 ) chromosome segregation protein SMC
• ( TIGR02169 ) chromosome segregation protein SMC
• ( TIGR02211 ) lipoprotein releasing system, ATP-binding protein
• ( TIGR02473 ) flagellar export protein FliJ
• ( TIGR03185 ) DNA sulfur modification protein DndD

Gene Expression Profile

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_02981.1	9.997093137033517e-262
	Description: SMC family domain-containing protein (1199 aa)
DictyBase	DDB_G0284499	9.997093137033517e-262
	Description: smc2 on chromosome: 4 position 2051268 to 2054927
Oxytricha	Contig3441.0.g49	9.997093137033517e-262
	Description: RecF/RecN/SMC N terminal domain
WormBase	WBGene00003367	2.999370583638828e-134
	Description: locus:mix-1 Mitotic chromosome and X-chromosome-associated protein mix-1 status:Confirmed UniProt:Q09591 protein_id:CAA87054.1
SGD	YFR031C	1.9992362000979228e-56
	Description: SMC2 Subunit of the condensin complex; essential SMC chromosomal ATPase family member that forms a complex with Smc4p to form the active ATPase; Smc2p/Smc4p complex binds DNA; required for clustering of tRNA genes at the nucleolus
Stentor Coeruleus	SteCoe_15774	0.0000000000002543665647376923
	Description: None

General Information

No Data fetched for General Information

Associated Literature

1. Ref:29237819: Howard-Till R, Loidl J (2018) Condensins promote chromosome individualization and segregation during mitosis, meiosis, and amitosis in Tetrahymena thermophila. Molecular biology of the cell 29(4):466-478

Sequences

>TTHERM_00812950(coding)
ATGTATATAAAAGAAATTATTATTGAAGGTTTCAAGAGTTACGCCACTCGTACAATTATT
AAGGGCTTTGATCAGTAATTCAATGCAATTACAGGTTTTAATGGATCTGGTAAGTCTAAT
ATCTTAGACTCTATCTTATTCGTTCTTGGTTTGAACAAAGATTGGGAACTGCTAAGAGTT
AAGAAGGTTCAAGAATTAGTTTATAAATAAGGTCATGCAGGTATAACAAAAGCAGAAGTT
ACAGTTATTTTCGACAATTCTAACAAAGAATAATCACCTCTTGGTTATGAATCATATGAC
ACAATTTCTGTTACTAGACAAGTCTAATAAGAAAAGAGTAAATACTTCGTTAATGGTACA
AAGCTTACTTTAAATCAAGTCAAAAATATGTTCAGAAGTGTTTAATTAAATATTGACAAT
CCTCACTTCTTGGTTGCTTAAGGTAGAATTACTAAGATCATCAACTTGAAACCTTAGGAA
CTCATTTCTATGCTTGAAGAAACTGCAGGAACTGCTCTCTACAATGAAAAGAAAAGAGAA
AGTGAAAAAATTATTAAGAAAAAAGAGGAAAAGGTTAAGGAAATCAATGATTTGATTGAT
ACAGATATCCAACCTAAAATGAGAAAGTTGAAAGAGGAAAAAGAACAATATTTGATTTGG
AAGAGCAGCGAAGTTGAAATCAACAAAATGGATAGAAAGCTTAAAGCTTATGAATATTTT
AATAAGAACAATCTTTTAAAGGAAAGAATGAGAGAAATAGAAAGCAAGCAAAGCATTCTC
ACACATGCTTAGAGAGAATTAACTAAGGTTACAAATGATTATTAGCAAGTTATTGATGAA
ATGAAAAACCATGGTAGAAAGCAAGATGCTGAAAAGGATAAACAACTCAGTCGTTATGAA
ATGGCACTGAAAAATTTGGAAGATACTATTTAAAGACAAGAAAAAGATCGTGAAACCATT
AAAAAATTTTAAATATCTTCTTTACAAGAATTAAAGAAGTAGGAAAATAAAGTTCGTTTA
TGCGAAGAAAATATTGCTAAATTTGAAAAGGATTTGGAATACTCTAGATAGTAGCTTGCT
GACCTTCAAGCTGAATATGATTAAAAGAAAGAAAATCTCAACGAAGTTAACAGACTTTCT
AAAAATGATTCTGGTAACATAGATGCTGCAAAGGAATAAGTTGATGAATAAATTGTATTC
ACAAAGAATAAACTCAGAAACTTTAAAAACGACATTGCTAAATTAGAAAATTCCATCAAG
CAAAAGCAAAATATCATCAAGAATTAAAAAGAAAATATTGAAAGTGCCTAAAGAGAAAGA
GAAAGTCTTAGCAAAAAGCTTGAAATCTTAGAAAAAGAAATTAAATAAGTTGAAGATGAC
ATCGATAAATGCACATTCAATGTCAATGAGCTCAGAGCAAGAGAAAACGAAAGAGCTAAC
TATGATCAATAAATTATGAAGCTTAATCACAACCTTGAAAATATTTTGAACCAAAATGGT
AACTGGATTTTCAAGCTTCAATTTAGAGACCCTGAACCTAATTTTGATAGAAGCAAAATT
AAGGGAAGAATTTTGACTTTATTCAAAGTAAAATCTCCTGAATATTTCGAAGCACTTGAA
GCTGGTGCAGGTGGAAAATTGCTAAATATTGTTACTGAAGATGAATAAACTTCTAAGTTA
ATGCTTAAAAAGAATTGCTTCTCTTTTAATGTTAGATTTATTCCTAACAATAAGATTGTT
AGCAGAAAGATTGATGAACAAATAGTTTAAGAAGCTTAACGTATTGCAAATGAAATGGGA
GGATGGGCTCTTCCTGCTTATGAACTTATCGAATATGATAAGTATTTAGAAAGAAGTATG
CTTTTTGTATTTGGAAACTTCATTGTTACTTCTAATCAACATATCGCTAAGTAGATAGCC
TTTAATTAGAATGTTAGAATGAGAATCAAGTGTGTCACTCTCGAAGGTGATATTATTGAT
CCTCAAGGTACTTTATAAGGTGGTTATCAAGATAATAGAAACCTCACACTTACTCGTTAT
GCTAATTATAGAAATATTTAAGACGAGAAAGAAGAAATAATCTACAATAAAGGTCAACTT
TAAGAAAGCATCAACTACCTTAAAAAAGAAGAAAATTATTATAATGGTTTGAAGGATGAT
TTAACAAATAAAAAATTCAGATTTGAAAAATTCGCTGAACAATTAAGAAATCTTTCTGGT
CGTGGTATCCAAGAGCAATAAGATAAGCTTGAAAGAGAAATTCAAGATGATATTGAAATG
CTTGCACGTGTTTAAGATCAAGACAAAAAGACTCAAGAAAAGCTTGAAGAATTGAATAAT
GAAAGAGCTAATCTCTCTAAATCTAAAGACACCAAGGAAGTTTGGAAAAAGAAAATCCAA
AAGCTCAAATAAGAAATAGAAGAAAGTGACAAGGAACTATAAAATTTAAACAATCACATT
GCCGACTGTGAAGTCAATATTGAACATAATAAAAAGGATTTAATCAAATCAAAAGACAGA
GTTATCTAAGAAAATAAAAATATAGAAGATCAAAAGAAAAAACTTGAAAGCAATGACTAA
GATTTGAACCAAAAGAGAAAGGAAAACTAAGAATTGAAGAGACAAAAAGATGAGCTTGAG
CTAGAAATTTAGAAGCTCTAAGGTAAGAGAGTTGAGCTTGAAGAAAAAGAAAAAACTCTT
AAGTAAAGAAAAGACGAAATAGAATCTGAAGTTAAGAAGATCGAAGAATTCAACAAAAAA
ATCACTGCAGAAATTACTGACATTCGTCTTTATCTCAATAATTTAGAAAAAGAAAATGAG
TTTATTAGAAATGATAAAGATCTTTTCGGCTAATAAGGAAGTGAGGACTACGACTTCTCT
AAATTTAACTTAAATGAACTTAAGAGAAGATACCATAACACTGTATAGGAACAACAAATA
AGATAAAAGCAAGTAAACTTTAAGGTTGAGGCCATGAGTGAAAAAGTAGAAAAAGATTAT
TAATAACTTAATGAAAAACGCCAAATTCTTGAAAATGATAAGATCCTCCTTTTCAAGAAC
ATGGACGAATTGGATAAGAAAAAGTAAGAAACTTTAGAAAAATGTTATTTGGAAGTTAAT
AAAACATTTGGCTAAATCTTTTCTGATCTTTTGCCAGGTGCTGCAGCTCGTATATAACCT
CCTGAAGGTCAAGATGTTTCTGCTGGTCTTGAATTGGGTGTTGCTTTCAACAATGTATGG
AAAACTTCTCTATCTGAATTATCAGGAGGTTAAAGATCACTTCTTGCTCTTTCTTTCGTA
CTTGCACTCCTTAAATATAAGCCTGCTCCTTTCTATATTTTGGATGAAGTAGATTCCGCT
TTGGATTTGTCTCATACTGAAAATATAGGTTATATGATTTCTCAAAGATTCCAAAACTCT
CAGTTCCTTCTTATTTCCTTAAAAGACGGTATGTATCAAAATGCTAATGTATTGTTTAAA
ACTTCCTTCGTTGACGGTGTATCTAAAGTTGACAGAATTCCATTAAAGAAAAAAATTACA
AATAACAATAAAAAGAAAAAAATGGAAGTTGAGGATGATAAAGAAAATTAAAATTGA

>TTHERM_00812950(gene)
ATGTATATAAAAGAAATTATTATTGAAGGTTTCAAGAGTTACGCCACTCGTACAATTATT
AAGGGCTTTGATCAGTAATTCAATGCAATTACAGGTTTTAATGGATCTGGTAAGTCTAAT
ATCTTAGACTCTATCTTATTCGTTCTTGGTTTGAACAAAGATTGGGAACTGGTAATTAAT
TAATTAATTATATTGACTATTCATAACTAGGCTATTAATTTTTACTTTCAGAGAATTAAT
AAATTATTTTATTTTTTTAATAATTCTAGCTAAGAGTTAAGAAGGTTCAAGAATTAGTTT
ATAAATAAGGTCATGCAGGTATAACAAAAGCAGAAGTTACAGTTATTTTCGACAATTCTA
ACAAAGAATAATCACCTCTTGGTTATGAATCATATGACACAATTTCTGTTACTAGACAAG
TAATTTATCATTTGAAATTCTCTTTGTAATTATTTTGCATGTTAAAAACGATATTGTTTT
TACATTCAATAATAATTTTTTTGAAAAATATTTTAAACTTAGGTCTAATAAGAAAAGAGT
AAATACTTCGTTAATGGTACAAAGCTTACTTTAAATCAAGTCAAAAATATGTTCAGAAGT
GTTTAATTAAATATTGACAATCCTCACTTCTTGGTTGCTTAAGGTAGAATTACTAAGATC
ATCAACTTGAAACCTTAGGAACTCATTTCTATGCTTGAAGAAACTGCAGGTATAAAAATT
ACTTTAGAAGGACAGCAAATAACTATTAAATGCTTGCTATTAATTACCTGATAAAAACAA
AATGTGCTTTCGAAAATCACATAAAAACAGCTTTGATATTAAATAACCATTTTGAATTAT
TTAATTTAATAATAAATAACACTTTAATATAAAAATAAGCCAAGAAATATCTTTTTTAAA
TTAAAAGCAAGAAGTTATTTTTAAAAATGGTTTTTGAGAATATTTTTTGGAATATTTTGA
ATAATTAATTTATCATGAATAATTAAAAATAGGAACTGCTCTCTACAATGAAAAGAAAAG
AGAAAGTGAAAAAATTATTAAGAAAAAAGAGGAAAAGGTTAAGGAAATCAATGATTTGAT
TGATACAGATATCCAACCTAAAATGAGAAAGTTGAAAGAGGAAAAAGAACAATATTTGAT
TTGGAAGAGCAGCGAAGTTGAAATCAACAAAATGGATAGAAAGCTTAAAGCTTATGAATA
TTTTAATAAGAACAATCTTTTAAAGGAAAGAATGAGAGAAATAGAAAGCAAGCAAAGCAT
TCTCACACATGCTTAGAGAGAATTAACTAAGGTTACAAATGATTATTAGCAAGTTATTGA
TGAAATGAAAAACCATGGTAGAAAGCAAGATGCTGAAAAGGATAAACAACTCAGTCGTTA
TGAAATGGCACTGAAAAATTTGGAAGATACTATTTAAAGACAAGAAAAAGATCGTGAAAC
CATTAAAAAATTTTAAATATCTTCTTTACAAGAATTAAAGAAGTAGGAAAATAAAGTTCG
TTTATGCGAAGAAAATATTGCTAAATTTGAAAAGGATTTGGAATACTCTAGATAGTAGCT
TGCTGACCTTCAAGCTGAATATGATTAAAAGAAAGAAAATCTCAACGAAGTTAACAGACT
TTCTAAAAATGATTCTGGTAACATAGATGCTGCAAAGGAATAAGTTGATGAATAAATTGT
ATTCACAAAGAATAAACTCAGAAACTTTAAAAACGACATTGCTAAATTAGAAAATTCCAT
CAAGCAAAAGCAAAATATCATCAAGAATTAAAAAGAAAATATTGAAAGTGCCTAAAGAGA
AAGAGAAAGTCTTAGCAAAAAGCTTGAAATCTTAGAAAAAGAAATTAAATAAGTTGAAGA
TGACATCGATAGTAAATTTTTATTATTTTTATTCTTAAATTCAAAATGCTCTATTAAAAA
TAGAATGCACATTCAATGTCAATGAGCTCAGAGCAAGAGAAAACGAAAGAGCTAACTATG
ATCAATAAATTATGAAGCTTAATCACAACCTTGAAAATATTTTGAACCAAAATGGTAACT
GGATTTTCAAGCTTCAAGTAATGAGACATTCATTATTTTTTCATTTAAATCTTTCAATAC
TTGTTTAATCACTTTTGTTTCAAATCAATAAAATATTTTTTTGAAATAATAAAGTTTAGA
GACCCTGAACCTAATTTTGATAGAAGCAAAATTAAGGGAAGAATTTTGACTTTATTCAAA
GTAAAATCTCCTGAATATTTCGAAGCACTTGAAGCTGGTGCAGGTATATTTGAATATTAA
TTAAATTTATTTTACAAAATAAATAAATAAATGCAATAATTTAGGTGGAAAATTGCTAAA
TATTGTTACTGAAGATGAATAAACTTCTAAGTTAATGCTTAAAAAGAATTGCTTCTCTTT
TAATGTTAGATTTATTCCTAACAATAAGATTGTTAGCAGAAAGATTGATGAACAAATAGT
TTAAGAAGCTTAACGTATTGCAAATGAAATGGGAGGATGGGCTCTTCCTGCTTATGAACT
TATCGAATATGATAAGTATTTAGAAAGAAGTATGCTTTTTGTATTTGGAAACTTCATTGT
TACTTCTAATCAACATATCGCTAAGTAGATAGCCTTTAATTAGAATGTTAGAATGAGAAT
CAAGTGTGTCACTCTCGAAGGTGATATTATTGATCCTCAAGGTACTTTATAAGGTGGTTA
TCAAGATAATAGAAACCTCACACTTACTCGTTATGCTAATTATAGAAATATTTAAGACGA
GAAAGAAGAAATAATCTACAATAAAGGTCAACTTTAAGAAAGCATCAACTACCTTAAAAA
AGAAGAAAATTATTATAATGGTTTGAAGGATGATTTAACAAATAAAAAATTCAGATTTGA
AAAATTCGCTGAACAATTAAGAAATCTTTCTGGTCGTGGTATCCAAGAGCAATAAGATAA
GCTTGAAAGAGAAATTCAAGATGATATTGAAATGCTTGCACGTGTTTAAGATCAAGACAA
AAAGACTCAAGAAAAGCTTGAAGAATTGAATAATGAAAGAGCTAATCTCTCTAAATCTAA
AGACACCAAGGAAGTTTGGAAAAAGAAAATCCAAAAGCTCAAATAAGAAATAGAAGAAAG
TGACAAGGAACTATAAAATTTAAACAATCACATTGCCGACTGTGAAGTCAATATTGAACA
TAATAAAAAGGATTTAATCAAATCAAAAGACAGAGTTATCTAAGAAAATAAAAATATAGA
AGATCAAAAGAAAAAACTTGAAAGCAATGACTAAGATTTGAACCAAAAGAGAAAGGAAAA
CTAAGAATTGAAGGTAAGAAAGCACATTTCATTATTCATAAATTAATTATCTCTTTTATA
TAAATTATATAGAGACAAAAAGATGAGCTTGAGCTAGAAATTTAGAAGCTCTAAGGTAAG
AGAGTTGAGCTTGAAGAAAAAGAAAAAACTCTTAAGTAAAGAAAAGACGAAATAGAATCT
GAAGTTAAGAAGATCGAAGAATTCAACAAAAAAATCACTGCAGAAATTACTGACATTCGT
CTTTATCTCAATAATTTAGAAAAAGAAAATGAGGTAATAAATATCATTTAAAAAATATAT
TTTTTTATTCCTTTTTTATATTTAATTCAATCTTACTTAATATCTATTTTTTAGTAGAAA
TCAAATTCTTTTTATTAATTTATCAAAATATTTCTTCTTTTACTTATTTATTTATTTATT
TATTTATTTATTTATTTATTTATTTATTTATTTGAGCAGATGCTTTGAAAAAAAAATTTA
AAATATCCTTAGCTTGTTTCAAATAAGATTTTAATAATTTAATATTTTGAAAATAATTTA
AAGAAAAATGTGATTAATTATTAGAATTATTGTTAAAATTTATAATAAATAATGAATGTA
TTTGTGCTAATTAAATTTTCTATTTTGATAATAAAATTAGTTTATTAGAAATGATAAAGA
TCTTTTCGGCTAATAAGGAAGTGAGGACTACGACTTCTCTAAATTTAACTTAAATGAACT
TAAGAGAAGATACCATAACACTGTATAGGAACAACAAATAAGATAAAAGCAAGTAAACTT
TAAGGTTGAGGCCATGAGTGAAAAAGTAGAAAAAGATTATTAATAACTTAATGAAAAACG
CCAAATTCTTGAAAATGATAAGATCCTCCTTTTCAAGAACATGGACGAATTGGATAAGAA
AAAGTAAGAAACTTTAGAAAAATGTTATTTGGAAGTTAATAAAACATTTGGCTAAATCTT
TTCTGATCTTTTGCCAGGTGCTGCAGCTCGTATATAACCTCCTGAAGGTCAAGATGTTTC
TGCTGGTCTTGAATTGGGTGTTGCTTTCAACAATGTATGGAAAACTTCTCTATCTGAATT
ATCAGGAGGTAATTAACTAACTATTTGATTATAATTATTTAATTTTATTTATTCAATTTT
ATTTATTTAACAGGTTAAAGATCACTTCTTGCTCTTTCTTTCGTACTTGCACTCCTTAAA
TATAAGCCTGCTCCTTTCTATATTTTGGATGAAGTAGATTCCGCTTTGGATTTGTCTCAT
ACTGAAAATATAGGTAAATAAATAAACTATTTCTTTAAATTAAATTACTTTTAACTTAAA
TTAAATAAAGGTTATATGATTTCTCAAAGATTCCAAAACTCTCAGTTCCTTCTTATTTCC
TTAAAAGACGGTATGTATCAAGTAAATCATTTCATCAAAATTATATTTGTGATTGTAAAA
TATATTTTAATTATTAAAGAATGCTAATGTATTGTTTAAAACTTCCTTCGTTGACGGTGT
ATCTAAAGTTGACAGAATTCCATTAAAGAAAAAAATTACAAATAACAATAAAAAGAAAAA
AATGGAAGTTGAGGATGATAAAGAAAATTAAAATTGA

>TTHERM_00812950(protein)
MYIKEIIIEGFKSYATRTIIKGFDQQFNAITGFNGSGKSNILDSILFVLGLNKDWELLRV
KKVQELVYKQGHAGITKAEVTVIFDNSNKEQSPLGYESYDTISVTRQVQQEKSKYFVNGT
KLTLNQVKNMFRSVQLNIDNPHFLVAQGRITKIINLKPQELISMLEETAGTALYNEKKRE
SEKIIKKKEEKVKEINDLIDTDIQPKMRKLKEEKEQYLIWKSSEVEINKMDRKLKAYEYF
NKNNLLKERMREIESKQSILTHAQRELTKVTNDYQQVIDEMKNHGRKQDAEKDKQLSRYE
MALKNLEDTIQRQEKDRETIKKFQISSLQELKKQENKVRLCEENIAKFEKDLEYSRQQLA
DLQAEYDQKKENLNEVNRLSKNDSGNIDAAKEQVDEQIVFTKNKLRNFKNDIAKLENSIK
QKQNIIKNQKENIESAQRERESLSKKLEILEKEIKQVEDDIDKCTFNVNELRARENERAN
YDQQIMKLNHNLENILNQNGNWIFKLQFRDPEPNFDRSKIKGRILTLFKVKSPEYFEALE
AGAGGKLLNIVTEDEQTSKLMLKKNCFSFNVRFIPNNKIVSRKIDEQIVQEAQRIANEMG
GWALPAYELIEYDKYLERSMLFVFGNFIVTSNQHIAKQIAFNQNVRMRIKCVTLEGDIID
PQGTLQGGYQDNRNLTLTRYANYRNIQDEKEEIIYNKGQLQESINYLKKEENYYNGLKDD
LTNKKFRFEKFAEQLRNLSGRGIQEQQDKLEREIQDDIEMLARVQDQDKKTQEKLEELNN
ERANLSKSKDTKEVWKKKIQKLKQEIEESDKELQNLNNHIADCEVNIEHNKKDLIKSKDR
VIQENKNIEDQKKKLESNDQDLNQKRKENQELKRQKDELELEIQKLQGKRVELEEKEKTL
KQRKDEIESEVKKIEEFNKKITAEITDIRLYLNNLEKENEFIRNDKDLFGQQGSEDYDFS
KFNLNELKRRYHNTVQEQQIRQKQVNFKVEAMSEKVEKDYQQLNEKRQILENDKILLFKN
MDELDKKKQETLEKCYLEVNKTFGQIFSDLLPGAAARIQPPEGQDVSAGLELGVAFNNVW
KTSLSELSGGQRSLLALSFVLALLKYKPAPFYILDEVDSALDLSHTENIGYMISQRFQNS
QFLLISLKDGMYQNANVLFKTSFVDGVSKVDRIPLKKKITNNNKKKKMEVEDDKENQN