Identifiers and Description

Gene Model Identifier

TTHERM_00823550

Standard Name

PRKA1 (homolog to human PRKAA1)

Aliases

PreTt20428 | 141.m00085 | 3682.m00019

Description

PRKA1 kinase domain protein; Sequence similarity to the AMPK subfamily of the protein kinase CAMKL family (Eisen et al.- 2006). homolog to the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK).

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Molecular Function

• ATP binding (IEA) | GO:0005524
• protein kinase activity (IEA) | GO:0004672
• protein tyrosine kinase activity (IEA) | GO:0004713

Biological Process

• protein phosphorylation (IEA) | GO:0006468

Domains

• ( PF00069 ) Protein kinase domain
• ( PF01163 ) RIO1 family
• ( PF07714 ) Protein tyrosine and serine/threonine kinase

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_18167.1	9.997093137033517e-262
	Description: protein kinase domain-containing protein (644 aa)
DictyBase	DDB_G0277905	6.0025840010353464e-108
	Description: snfA on chromosome: 3 position 589784 to 592434
WormBase	WBGene00020142	1.0000943968537097e-101
	Description: locus:aak-2 5-AMP-activated protein kinase catalytic subunit alpha-2 status:Confirmed UniProt:Q95ZQ4 protein_id:CCD68834.1
SGD	YDR477W	5.001580789778561e-97
	Description: SNF1 AMP-activated serine/threonine protein kinase found in a complex containing Snf4p and members of the Sip1p/Sip2p/Gal83p family; required for transcription of glucose-repressed genes, thermotolerance, sporulation, and peroxisome biogenesis
Oxytricha	Contig4414.0.g90	2.998893725394183e-91
	Description: Protein kinase domain
Stentor Coeruleus	SteCoe_23142	2.031092662734811e-42
	Description: None

General Information

No Data fetched for General Information

Associated Literature

1. Ref:16933976: Eisen JA, Coyne RS, Wu M, Wu D, Thiagarajan M, Wortman JR, Badger JH, Ren Q, Amedeo P, Jones KM, Tallon LJ, Delcher AL, Salzberg SL, Silva JC, Haas BJ, Majoros WH, Farzad M, Carlton JM, Smith RK, Garg J, Pearlman RE, Karrer KM, Sun L, Manning G, Elde NC, Turkewitz AP, Asai DJ, Wilkes DE, Wang Y, Cai H, Collins K, Stewart BA, Lee SR, Wilamowska K, Weinberg Z, Ruzzo WL, Wloga D, Gaertig J, Frankel J, Tsao CC, Gorovsky MA, Keeling PJ, Waller RF, Patron NJ, Cherry JM, Stover NA,

Sequences

>TTHERM_00823550(coding)
ATGACAAGTACAAATAGCGGAAACACATTAAAAATTGAGCATTATCTTGTAGGAAAAACA
TTAGGGTGCGGAGCTTCTGGAAAAGTTAAGCTTGCCAAGCATGATATAACTGGAAAAGAA
GTTGCAATAAAAATTATAAATAAGAAAAAAATGACTGTTAAAAAAATGAGCAACAAGATT
AAAAGAGAAATTAGGCTTTTAAGATTCTTCAACCATTAAAACATTATTCGTTTATATGAA
GTTCTTGATACTAATACTGATATTTTTGTGGTTACTGAGTATATTTCAGGGGGAGATTTA
TATGATGTTATTGCTTCAAAGGGTAAGCTTCCTGAATAAGAAGCAAAAAGATATTTTAAG
TAAATAGTAGCAGGAGTTGATTACTGCCATAGAAACTTAGTCGCCCATAGAGATCTGAAA
CTTGAAAATATATTAATAGATGATAATAATAACATTAAAATTGCAGATTTTGGTTTGAGT
AATATTATGAATGATGGTAAATATTTGTCTACATCTTGTGGTTCTCCTAATTACGCTGCC
CCAGAAGTTATATCTGGAAAACTATATTGTGGAACAGAAGTTGATACTTGGAGTTGTGGT
GTTATATTATTCGCCTTGCTAGGAGGCTATCTTCCTTTTGATGAAGAAGTTATTCCAGCT
TTGTATAAGAAAATCAAGGAGGGAGATTTTCAGATTCCAGCATTTTTTTCACCTGAAGCT
CATGATATAATTAAAAGAATGCTCCGTCCTAACCCTATAGAGAGAATTAAATTTCATGAA
TTGAGACTTCATCCTTGGTTGAGAGAAAATGTTCCCTTTTATGTAGAAATATTCAATTAG
AATACAAGAATGGAGAGTAAAAAATTAAATGAAGACATTTTGAGAAAATTAGCTTAAATG
AAAAATGTTAACTTCCATAATTTGAACGAATAAACTATTAGAGATGCCGTTATTAAGAGA
GACGATTATAGTTTTGTTATTGCTTACGATTTGCTCCTTGATGACTATAAAAAGAACAAC
TATTATAATAAAGAAAACAATCAAAACACTTTCATATTCAGACCTGTTTAAGAAGACTGC
ACAGTCGAGACCAATAATGCTTATATTGATCAAATCTTTAATCAAGGAAAACTTGAAGAA
GTAACTGAGGAAGAAGAAGAAATACTTGGCCAGTGGACTTATGGAAAGATATATAGCAAT
AGTGCTAGGACAATTATGAAAGCAATATATGAGGTTGCAAGCTAGTTAGATATTGTTATT
ACAATTAAAAATAGCGAATATAGGATCAAATGCCATAGAAAAAACCCTAAAAAGATCTAA
AGTGCTTACAACAACCATCTTGAAACTATAAAAAGTGAAAGTAGCTCAAATTTATCAACA
AATTACACAAATAATGGTAATTTAAACAACAGCCACCACCATCACCACTCATACAATAAT
CATTACCATCATGTTAATCCATAGAATTAAAATTTTACTGGCTTCTAGAGTGGATCAAAT
GTTTCTATGACAAACAACTTTTAGCACACATAAACTAATTCCTATTTAATGCCTCCCTAA
GGTAATTAATTTAATAATTAAATGAGTAATGTAAGCAATGACTTTGGATAAAATATGGAA
TCTCAATCTTAATCTTATGCCATAGGTAGCAATTTCAATAATATGAATTATAGTCAATCG
GGATATTAATTTGATTCTGGAATGAATCTAAATAATGGTAACACTTAAAACCCAAATAAC
AGTTAAAATAATGCTCTTGACACTAATAACATACCTAAATTCTCCAAATAGGATCTTGTT
TTTACCATATAAATATACTAAATGCCAAGCACTTCAATTCAAAGCGATTAGCACATAGTA
GATGTCATTTTAAATAAGGGTCATCCTATCATGTTCTTAGAGTTTTTTAACTAATTTCTT
ACTCTTGTAAACAAAAAACTTAATCCAATTCACTGA

>TTHERM_00823550(gene)
ATGACAAGTACAAATAGCGGAAACACATTAAAAATTGAGCATTATCTTGTAGGAAAAACA
TTAGGGTGCGGAGCTTCTGGAAAAGTTAAGCGTGAGTAGTTTAGATTATTTAAAGTACTT
CGAATAAGCTGAATCAAAAATTTTTTAACCAAGTAGTTAACGTTTTTTAGAGGAGTATAA
TTTACTCTCCTCATCAATCAATCAAGTTTTAATTAAGATGCATTTTTATAGGCCTTTCAT
CAGAAAATGCTAAAATATTTTCTAAAAAAAGCGAATTCAAAAATATTTTTTGTTTTATAA
TAGTTGCCAAGCATGATATAACTGGAAAAGAAGTTGCAATAAAAATTATAAATAAGAAAA
AAATGACTGTTAAAAAAATGAGCAACAAGGTAAGCTTATATTTTTTAAAGATTTTAAGCG
CTTTTTTCACATTCTTAGATAAGCATATAAAAATAATAAGCTTTTTGATAACAATTTATT
TAAAAAATTTAATCTTAGTATTAGCTATGCTTGTTTTAATTAAGTAGAAACTTTAGAGTA
CAAATATTTATGCATTTTTGTTTTTTATTTAAAGATTAAAAGAGAAATTAGGCTTTTAAG
ATTCTTCAACCATTAAAACATTATTCGTTTATATGAAGTTCTTGATACTAATACTGATAT
TTTTGTGGTTACTGAGTATATTTCAGGGGGAGATTTATATGATGTTATTGCTTCAAAGGG
TAAGCTTCCTGAATAAGAAGCAAAAAGATATTTTAAGTAAATAGTAGCAGGAGTTGATTA
CTGCCATAGAAACTTAGTCGCCCATAGAGATCTGAAACTTGAAAATATATTAATAGATGA
TAATAATAACATTAAAATTGCAGATTTTGGTTTGAGTAATATTATGAATGATGGTAAATA
TTTGTCTACATCTTGTGGTTCTCCTAATTACGCTGCCCCAGAAGTTATATCTGGAAAGTA
AGTTAATTAAATTTTGTTTAAATATGATTTTAAATAAATTCTAATACATATTGATTGTTC
AAGAACTAATAATTTTTATGACTTCAATTTACATTAATTAAGTTTCTGTCAATTTTATTT
TGGTATTTAAAAAAATAAATAAAAAAAGTAAACAAACAAACAAACAATCAATCAAAAAAA
CATTTAAAAAGATCTAGCACTAAAATTTGACTAAAAATATTACAATTTTAAATAAAACGA
TGCTGTTAAAACTTATTATAATTTTTGAATAAATAGACTATATTGTGGAACAGAAGTTGA
TACTTGGAGTTGTGGTGTTATATTATTCGCCTTGCTAGGAGGCTATCTTCCTTTTGATGA
AGAAGTTATTCCAGCTTTGTATAAGAAAATCAAGGGTATAAAATATATTTTTTTTATGTA
AAAATAGAAACAAACAAGCACTAATAAATTAAATAAATTGAATAAATTTATTCATTGATT
TCCTGAATCAGTCTTTTTGTATATTGATTATCAAATAAATATTTAAAAGAGGGAGATTTT
CAGATTCCAGCATTTTTTTCACCTGAAGCTCATGATATAATTAAAAGAATGCTCCGTCCT
AACCCTATAGAGAGAATTAAATTTCATGAATTGAGACTTCATCCTTGGTTGAGAGAAAAT
GTTCCCTTTTATGTAGAAATATTCAATTAGAATACAAGAATGGAGAGTAAAAAATTAAAT
GAAGACATTTTGAGAAAATTAGCTTAAATGAAAAATGTTAACTTCCATAATTTGAACGAA
TAAACTATTAGAGATGCCGTTATTAAGAGAGACGATTATAGTTTTGTTATTGCTTACGAT
TTGCTCCTTGATGACTATAAAAAGAACAACTATTATAATAAAGGTATTTATTTATTTATT
ATTCTTTTTCCAACTAACAAAAAATAAATAACATTTTTGATAGAAAACAATCAAAACACT
TTCATATTCAGACCTGTTTAAGAAGACTGCACAGTCGAGACCAATAATGCTTATATTGAT
CAAATCTTTAATCAAGGGTATTAATAGATATTTCTTTTACAAGTTATTTGCTTTTTCCTT
AAAAAGGTTCAAAAATAAATATTTTGAGCAGAAAAAATTTAATCAATGTCACTAAACAAA
CCCTAATGTGTAATATATAATTTTTATTGATTTAGAAAACTTGAAGAAGTAACTGAGGAA
GAAGAAGAAATACTTGGCCAGTGGACTTATGGAAAGATATATAGCAATAGTGCTAGGACA
ATTATGAAAGCAATATATGAGGTTGCAAGCTAGTTAGATATTGTTATTACAATTAAAAAT
AGCGAATATAGGATCAAATGCCATAGAAAAAACCCTAAAAAGATCTAAAGTGCTTACAAC
AACCATCTTGAAACTATAAAAAGTGAAAGTAGCTCAAATTTATCAACAAATTACACAAAT
AATGGTAATTTAAACAACAGCCACCACCATCACCACTCATACAATAATCATTACCATCAT
GTTAATCCATAGAATTAAAATTTTACTGGCTTCTAGAGTGGATCAAATGTTTCTATGACA
AACAACTTTTAGCACACATAAACTAATTCCTATTTAATGCCTCCCTAAGGTAATTAATTT
AATAATTAAATGAGTAATGTAAGCAATGACTTTGGATAAAATATGGAATCTCAATCTTAA
TCTTATGCCATAGGTAGCAATTTCAATAATATGAATTATAGTCAATCGGGATATTAATTT
GATTCTGGAATGAATCTAAATAATGGTAACACTTAAAACCCAAATAACAGTTAAAATAAT
GCTCTTGACACTAATAACATACCTAAATTCTCCAAATAGGATCTTGTTTTTACCATATAA
ATATACTAAGTAACTCACTCACTCTCTTTAACATTATTGAAATAATTTTTAATTTATTTC
TTTTGTAAAAAAGATGCCAAGCACTTCAATTCAAAGCGATTAGCACATAGTAGATGTCAT
TTTAAATAAGGGTCATCCTATCATGTTCTTAGAGTTTTTTAACTAATTTCTTACTCTTGT
AAACAAAAAACTTAATCCAATTCACTGA

>TTHERM_00823550(protein)
MTSTNSGNTLKIEHYLVGKTLGCGASGKVKLAKHDITGKEVAIKIINKKKMTVKKMSNKI
KREIRLLRFFNHQNIIRLYEVLDTNTDIFVVTEYISGGDLYDVIASKGKLPEQEAKRYFK
QIVAGVDYCHRNLVAHRDLKLENILIDDNNNIKIADFGLSNIMNDGKYLSTSCGSPNYAA
PEVISGKLYCGTEVDTWSCGVILFALLGGYLPFDEEVIPALYKKIKEGDFQIPAFFSPEA
HDIIKRMLRPNPIERIKFHELRLHPWLRENVPFYVEIFNQNTRMESKKLNEDILRKLAQM
KNVNFHNLNEQTIRDAVIKRDDYSFVIAYDLLLDDYKKNNYYNKENNQNTFIFRPVQEDC
TVETNNAYIDQIFNQGKLEEVTEEEEEILGQWTYGKIYSNSARTIMKAIYEVASQLDIVI
TIKNSEYRIKCHRKNPKKIQSAYNNHLETIKSESSSNLSTNYTNNGNLNNSHHHHHSYNN
HYHHVNPQNQNFTGFQSGSNVSMTNNFQHTQTNSYLMPPQGNQFNNQMSNVSNDFGQNME
SQSQSYAIGSNFNNMNYSQSGYQFDSGMNLNNGNTQNPNNSQNNALDTNNIPKFSKQDLV
FTIQIYQMPSTSIQSDQHIVDVILNKGHPIMFLEFFNQFLTLVNKKLNPIH