Identifiers and Description

Gene Model Identifier

TTHERM_00823980

Standard Name

PARP4 (Poly [ADP-Ribose] Polymerase 4)

Aliases

PreTt20466 | 141.m00123 | 3682.m00057

Description

PARP4 poly(ADP-ribose) polymerase family WGR domain protein; WGR domain containing protein

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Molecular Function

• NAD+-protein poly-ADP-ribosyltransferase activity (IEA) | GO:0003950

Biological Process

• obsolete protein ADP-ribosylation (IEA) | GO:0006471

Domains

• ( PF00644 ) Poly(ADP-ribose) polymerase catalytic domain
• ( PF02877 ) Poly(ADP-ribose) polymerase, regulatory domain
• ( PF05406 ) WGR domain

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_18135.1	9.997093137033517e-262
	Description: WGR domain-containing protein (614 aa)
Oxytricha	Contig12012.0.g59	8.000542080162695e-100
	Description: Poly(ADP-ribose) polymerase catalytic domain
DictyBase	DDB_G0292820	6.997716170296885e-95
	Description: adprt2 on chromosome: 6 position 2124835 to 2127096
WormBase	WBGene00004049	6.996751372006089e-64
	Description: locus:pme-1 Poly(ADP-ribose) polymerase pme-1 status:Confirmed UniProt:Q9N4H4 protein_id:CCD73512.1
WormBase	WBGene00001564	6.996751372006089e-64
	Description: locus:icl-1 status:Confirmed UniProt:Q8IA71 protein_id:CCD63239.1
Stentor Coeruleus	SteCoe_27180	3.4811068399043105e-57
	Description: None

General Information

No Data fetched for General Information

Associated Literature

1. Ref:30796450: Ashraf K, Nabeel-Shah S, Garg J, Saettone A, Derynck J, Gingras AC, Lambert JP, Pearlman RE, Fillingham J (2019) Proteomic analysis of histones H2A/H2B and variant Hv1 in Tetrahymena thermophila reveals an ancient network of chaperones. Molecular biology and evolution ( ):

Sequences

>TTHERM_00823980(coding)
ATGCCTCCTAAAAGAGCTACTAGATCTTAATCTGCAGCAGCAGCAACTAAAGGTAAATAG
GCTGCTACAAAAACTACAAAAAAAGATGCCAAGATTGAGGATAAAAAAGTGACTAGAGGA
AGAAAAGCAGCCACTAAATCTCCTTCTCCTTCCCCTTCACCTAAAAAAACCCAAAAAGGT
AAACCTGCAGCAGCTTCTAAATCTAAATCTAAAGATACTAAAGTCGCAACAGTAGATAAG
AAAAACACAAAAGCAGCTTAGAAAACTACTTAAAAAACAAAGTAAGCAAAAACAGCACCA
GCACCTTCTCCCAAAAAAACCAATAAAAGAAAAGCTAAGAGTGTATCTCCCTCCCCAGAT
ACAAAGGCCTAAACTAAAAAGAGTCCTGTCAAAAAAGTCAAAGATGTACCCAAAAAAGAT
GAATCTGAAGATGAGAAAAAAACTGTTAAATAGATCGTTAAAGGTAAATGTGCAGTTGAT
TAGTATGTACCAAATTCAACACAATACACAGTTCTATAAGAAGGAAACTAAATTTACAAT
CTTACTTTGAATCAATCAAATGTTGATGCAAACAATAACAAATTCTATCTTGGATAGGTG
CTTGTTAAAGATGGAACTAATCAATACTCCGTTTTCTTTAGATGGGGAAGAGTTGGTGTT
CCAGGACAATAAAGCATTAAAGTTTGTTCAAGTAAATTTGAAGCTATTAGCGAATTCTAA
AAAAAGAAAAGCGATAAAATTAAAGGAGGTTATACTGAAATTTTCATCAAATATGGTGAA
GATGATGAAGATGAAAAGCCAAAGAAAAAATAAACTACTTAACCTACAAAGAGAAAAGAT
TGTACTTTATCTGCTGCAGTTCAAACCTTGATAAACGACATTTTTGATATGAAAATGATT
GAGAGTACAATTAAAGAAATAGGTTATGATTCTAAAAAGATGCCTTTAGGTAAACTTGAC
GATAAAACAATTAAATAAGCTTACACTGTTCTCAAAGATCTTTTAGATGCTGTAAAAAAT
AATAAAGTTAGTGATTATGGTCGTTATTCTAGTTAATTCTACTCCCTTATTCCTCATGAT
TTTGGTTTCTAAAAAATGAGTAACTTCATTTTAAAAACTGAGGAATAAGTGCGTAAGAAG
CTTTCAATGCTTTAAGATTTATCTGACTTAAAAATTGCAACTCAATTACTTAAAGAATCA
GATTCAGATGACTCAATCTTAGATTAAAACTATAAAAAATTAAATGCAGAAATAAAAGAA
GTCACAGATAAAAAGACATTAGACATTATTAAGAATTATGTTAATCAAGGCAAAGGACAT
TATAGCCCTAAGATTTTAGAAATATTTTCAGTAAAAAGAAAAGGCGAGCAAGAACGTTAC
TCAAAAAATATTGGAAACGATACACTCTTATGGCATGGGTCCCGTATTTCAAACTTTGTT
GGTATATTATCTTAAGGTCTTCGTATTGCTCCTCCTGAGGCTCCTGTTACTGGTTATAAT
TATGGTAAGGGTATTTACCTTGCAGATTAATTTACTAAATCTTGTGATTATTGTGCAGGT
AATAGTGATGGTATCCATTACATCATGCTCATAAAGGCTGCTCTAGGAACTCCTAACAAA
ATAGAAAAAACTGATTATAATGCTAATAATCTTCCTAAAGGAACTCATTCTTGCTGGGGT
TGGGGTACTCATGGTCCTGAAGAATTCATAACATTTAATGGAGTTAAAGTACCTAAAGGC
TAGGAAGTTAGAACTAAATCTAAGCACTATATGAAATATAACGAGTTTATCATTTATGAT
ATTGCTTAAGCTCAAATAGATTATCTAATTAGATTTAAAAAGTACTGA

>TTHERM_00823980(gene)
ATGCCTCCTAAAAGAGCTACTAGATCTTAATCTGCAGCAGCAGCAACTAAAGGTAAATAG
GCTGCTACAAAAACTACAAAAAAAGATGCCAAGATTGAGGATAAAAAAGTGACTAGAGGA
AGAAAAGCAGCCACTAAATCTCCTTCTCCTTCCCCTTCACCTAAAAAAACCCAAAAAGGT
AAACCTGCAGCAGCTTCTAAATCTAAATCTAAAGATACTAAAGTCGCAACAGTAGATAAG
AAAAACACAAAAGCAGCTTAGAAAACTACTTAAAAAACAAAGTAAGCAAAAACAGCACCA
GCACCTTCTCCCAAAAAAACCAATAAAAGAAAAGCTAAGAGTGTATCTCCCTCCCCAGAT
ACAAAGGCCTAAACTAAAAAGAGTCCTGTCAAAAAAGTCAAAGATGTACCCAAAAAAGAT
GAATCTGAAGATGAGAAAAAAACTGTTAAATAGATCGTTAAAGGTATTTAATTGATATTA
AATAATTAACATAAAAATAATCATTATATTACTGGTATCATTTATATTTAATACTTAAAT
ATTTTTTATAAAGGTAAATGTGCAGTTGATTAGTATGTACCAAATTCAACACAATACACA
GTTCTATAAGAAGGAAACTAAATTTACAATCTTACTTTGAATCAATCAAATGTTGATGCA
AACAATAACAAATTCTATCTTGGATAGGTGCTTGTTAAAGATGGAACTAGTATAAATCCT
ATTTTTTTAAAAAAAATATATTAAATTTATTTCTATAAAAAGATCAATACTCCGTTTTCT
TTAGATGGGGAAGAGTTGGTGTTCCAGGACAATAAAGCATTAAAGTTTGTTCAAGTAAAT
TTGAAGCTATTAGCGAATTCTAAAAAAAGAAAAGCGATAAAATTAAAGGAGGTTATACTG
AAATTTTCATCAAATATGGTGAAGATGATGAAGATGAAAAGCCAAAGAGTAATTTTAATA
GAATTAATTAATTAATTTATTTATTTATTTTTAAAAATGTGTTGAAATTAGAAAAATAAA
CTACTTAACCTACAAAGAGAAAAGATTGTACTTTATCTGCTGCAGTTCAAACCTTGATAA
ACGACATTTTTGATATGAAAATGATTGAGAGTACAATTAAAGAAATAGGTTATGATTCTA
AAAAGATGCCTTTAGGTAAACTTGACGATAAAACAATTAAATAAGCTTACACTGTTCTCA
AAGATGTAACTAGAAATTAAAAACACTTAAAATTTAAATTTAAAATACCTTTTATGTGAT
ATTAAATAGCTTTTAGATGCTGTAAAAAATAATAAAGTTAGTGATTATGGTCGTTATTCT
AGTTAATTCTACTCCCTTATTCCTCATGATTTTGGTTTCTAAAAAATGAGTAACTTCATT
TTAAAAACTGAGGAATAAGTGCGTAAGAAGCTTTCAATGCTTTAAGATTTATCTGACTTA
AAAATTGCAACTCAATTACTTAAAGAATCAGATTCAGATGACTCAATCTTAGATTAAAAC
TATAAAAAATTAAATGCAGAAATAAAAGAAGTCACAGATGTAAACATTTAAATTATTTTA
GTTAAAAGAAATTGAGATAAAAATATCTTATCATTTTTAATGTTTGTTTTAAGCTTTAAA
AAAATAAATTCTAATATCTTCAAATTTGAGAAAAGTTTAATGAAGAAAATATACAACTAA
GCAAGCATAATTAAATTCATAGGTTTTGATTTAAAATAAAATAAAAAACATTTTGAGATC
TAATAGATTAAAATATTAATTTATTAAGTTAGTTAATTAGTTGGTTACACTTAGAAATCA
TTTATTTTTTTTTGATTAAGTTAGAATTCAAGTGATAAAGCATTATTTATTTTTAATAAT
TTAATAGAAAAAGACATTAGACATTATTAAGAATTATGTTAATCAAGGCAAAGGACATTA
TAGCCCTAAGATTTTAGAAATATTTTCAGTAAAAAGAAAAGGCGAGCAAGAACGTTACTC
AAAAAATATTGGAAACGATACACTCTTATGGCATGGGTCCCGTATTTCAAACTTTGTTGG
TATATTATCTTAAGGTCTTCGTATTGCTCCTCCTGAGGCTCCTGTTACTGGTATAAATTA
ATAATTAAATAGATAAAATATCCAATATGAATTGATTTTTTTTAATTTTAGGTTATAATT
ATGGTAAGGGTATTTACCTTGCAGATTAATTTACTAAATCTTGTGATTATTGTGCAGGTA
ATAGTGATGGTATCCATTACATCATGCTCATAAAGGCTGCTCTAGGAACTCCTAACAAAA
TAGAAAAAACTGATTATAATGCTAATAATCTTCCTAAAGGAACTCATTCTTGCTGGGGTT
GGGGTACTCATGGTCCTGAAGAATTCATAACATTTAATGGAGTTAAAGTACCTAAAGGCT
AGGAAGTTAGAACTAAATCTAAGGTAAATAATTTTAAAAATTACTATTTTATTCATTTGT
TTCTATTTAATTTATTAGCACTATATGAAATATAACGAGTTTATCATTTATGATATTGCT
TAAGCTCAAATAGATTATCTAATTAGATTTAAAAAGTACTGA

>TTHERM_00823980(protein)
MPPKRATRSQSAAAATKGKQAATKTTKKDAKIEDKKVTRGRKAATKSPSPSPSPKKTQKG
KPAAASKSKSKDTKVATVDKKNTKAAQKTTQKTKQAKTAPAPSPKKTNKRKAKSVSPSPD
TKAQTKKSPVKKVKDVPKKDESEDEKKTVKQIVKGKCAVDQYVPNSTQYTVLQEGNQIYN
LTLNQSNVDANNNKFYLGQVLVKDGTNQYSVFFRWGRVGVPGQQSIKVCSSKFEAISEFQ
KKKSDKIKGGYTEIFIKYGEDDEDEKPKKKQTTQPTKRKDCTLSAAVQTLINDIFDMKMI
ESTIKEIGYDSKKMPLGKLDDKTIKQAYTVLKDLLDAVKNNKVSDYGRYSSQFYSLIPHD
FGFQKMSNFILKTEEQVRKKLSMLQDLSDLKIATQLLKESDSDDSILDQNYKKLNAEIKE
VTDKKTLDIIKNYVNQGKGHYSPKILEIFSVKRKGEQERYSKNIGNDTLLWHGSRISNFV
GILSQGLRIAPPEAPVTGYNYGKGIYLADQFTKSCDYCAGNSDGIHYIMLIKAALGTPNK
IEKTDYNANNLPKGTHSCWGWGTHGPEEFITFNGVKVPKGQEVRTKSKHYMKYNEFIIYD
IAQAQIDYLIRFKKY