Identifiers and Description

Gene Model Identifier

TTHERM_00825380

Standard Name

FZY2 (FiZzY 2)

Aliases

PreTt04002 | 142.m00099 | 3683.m00032

Description

FZY2 WD regulatory protein putative; Fizzy/CDC20/CDH1 family protein; homolog of S. cerevisiae CDH1, a cell cycle regulated activator of the anaphase-promoting complex /cyclosome (APC/C), which directs ubiquitination of various targets; promotes cell growth during the G1 phase; WD repeat Cdc20/Fizzy

Genome Browser (Macronucleus)

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Genome Browser (Micronucleus)

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External Links

Gene Ontology Annotations

Cellular Component

Molecular Function

Biological Process

  • 3-keto-sphinganine metabolic process (IEA) | GO:0006666
  • absorption of visible light (IEA) | GO:0016038
  • bronchiole development (IEA) | GO:0060435
  • bronchus development (IEA) | GO:0060433
  • bud dilation involved in lung branching (IEA) | GO:0060503
  • carotenoid metabolic process (IEA) | GO:0016116
  • cell migration in diencephalon (IEA) | GO:0061381
  • ceramide phosphoethanolamine catabolic process (IEA) | GO:1905372
  • ceramide phosphoethanolamine metabolic process (IEA) | GO:1905371
  • epithelial cell proliferation involved in lung bud dilation (IEA) | GO:0060505
  • epithelial cell proliferation involved in lung morphogenesis (IEA) | GO:0060502
  • epithelium development (IEA) | GO:0060429
  • eukaryotic translation initiation factor 2B complex assembly (IEA) | GO:1905173
  • heme A biosynthetic process (IEA) | GO:0006784
  • heme biosynthetic process (IEA) | GO:0006783
  • inactivation of MAPK activity involved in osmosensory signaling pathway (IEA) | GO:0000173
  • inferior colliculus development (IEA) | GO:0061379
  • lung connective tissue development (IEA) | GO:0060427
  • negative regulation of cellular glucuronidation (IEA) | GO:2001030
  • negative regulation of double-strand break repair via nonhomologous end joining (IEA) | GO:2001033
  • negative regulation of epidermal growth factor receptor signaling pathway involved in heart process (IEA) | GO:1905283
  • negative regulation of interleukin-27-mediated signaling pathway (IEA) | GO:0070108
  • negative regulation of PERK-mediated unfolded protein response (IEA) | GO:1903898
  • neutral lipid metabolic process (IEA) | GO:0006638
  • obsolete aerotaxis on or near other organism involved in symbiotic interaction (IEA) | GO:0052238
  • obsolete induction by organism of defense-related symbiont reactive oxygen species production (IEA) | GO:0052401
  • obsolete inhibition of APC-Cdc20 complex activity (IEA) | GO:0060565
  • obsolete mitochondrial aspartate/glutamate transport (IEA) | GO:0006845
  • obsolete mRNA endonucleolytic cleavage involved in unfolded protein response (IEA) | GO:0070055
  • obsolete negative regulation of adhesion of symbiont to host epithelial cell (IEA) | GO:1905227
  • obsolete negative regulation of telomeric RNA transcription from RNA pol II promoter (IEA) | GO:1901581
  • obsolete pathogen-associated molecular pattern dependent modulation by organism of symbiont innate immunity (IEA) | GO:0052499
  • obsolete positive regulation of adhesion of symbiont to host epithelial cell (IEA) | GO:1905228
  • obsolete regulation of transcription from RNA polymerase II promoter involved in lung bud formation (IEA) | GO:0060500
  • ommochrome biosynthetic process (IEA) | GO:0006727
  • phagocytosis (IEA) | GO:0006909
  • plant-type cell wall modification (IEA) | GO:0009827
  • positive regulation by organism of phytoalexin production in other organism involved in symbiotic interaction (IEA) | GO:0052329
  • positive regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process (IEA) | GO:1902643
  • positive regulation of double-strand break repair via nonhomologous end joining (IEA) | GO:2001034
  • positive regulation of glutamate neurotransmitter secretion in response to membrane depolarization (IEA) | GO:0061646
  • positive regulation of interleukin-27-mediated signaling pathway (IEA) | GO:0070109
  • positive regulation of macropinocytosis (IEA) | GO:1905303
  • positive regulation of mitotic sister chromatid segregation (IEA) | GO:0062033
  • positive regulation of oxidative phosphorylation (IEA) | GO:1903862
  • positive regulation of protein autoubiquitination (IEA) | GO:1902499
  • positive regulation of retrograde transport, endosome to Golgi (IEA) | GO:1905281
  • propan-2-ol biosynthetic process (IEA) | GO:1902640
  • protein localization to old growing cell tip (IEA) | GO:1903858
  • regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process (IEA) | GO:1902641
  • regulation of cellular glucuronidation (IEA) | GO:2001029
  • regulation of cytokinin dehydrogenase activity (IEA) | GO:1903856
  • regulation of interleukin-27-mediated signaling pathway (IEA) | GO:0070107
  • regulation of phosphorus utilization (IEA) | GO:0006795
  • release of sequestered calcium ion into cytosol by endoplasmic reticulum (IEA) | GO:1903514
  • response to iron(III) ion (IEA) | GO:0010041
  • response to methamphetamine hydrochloride (IEA) | GO:1904313
  • RNA editing (IEA) | GO:0016547
  • sperm aster formation (IEA) | GO:0035044
  • synaptic vesicle docking (IEA) | GO:0016081
  • terpenoid catabolic process (IEA) | GO:0016115
  • tertiary alcohol biosynthetic process (IEA) | GO:1902645

Domains

  • ( PF00400 ) WD domain, G-beta repeat
  • ( PF12894 ) Anaphase-promoting complex subunit 4 WD40 domain

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

No Data fetched for Homologs

General Information

No Data fetched for General Information

Associated Literature

No Data fetched for Associated Literature

Sequences 

>TTHERM_00825380(coding)
ATGATTCTTTTTAAAAAACATCAATAAATTTAATATTTGCAAATGGTTTGGAGTGTTTTA
TTTTTAATTAATACTAATAAATAATAATAAAAAAGGATTTCTGTCAAGCCTTTAATTTTA
TTTGTCAATAATTAAAAGATATTTATGCAAATAAAAAATATTACAATTGCTGAACAAAAT
CTTAAATAAATTAATCATAATATAAATTCCCGCAAATTGATCGGCTATCTATCTTCAATA
TAAATTATTTAAATCATTAAAATTCAAGCAAATTAAACATAAAGACAAGATAAAGCGCAA
CCTATTTACCAGTGGTTTCTAACACAACTAATACAGCTTAACAGTTTTGAATATCCTCAT
CTTTTAAAGCATATACAATTTCTTATTTTTTATTGCTAGCCTCTCCTCAGCTCTTCAATA
AATCCTTTCAGACTCCGAAAATCAACTTTTATTATTTCTTAATAACATTCCTATTTAATA
ATTAACTCTATGAGTGAGATATAAATTGAAGAATAACCCTTTTGCTTTAATATAGGATTA
AATGAAAATGAACTAAACTCATCCTTCTGTTCACAAAATATTGAATAGGAGCTTTACAAA
AAGCAGAATTCTTAAGCTAGTCTCTATTTTTAATCTATTTCTTAGTAGGATAATACTAGT
GACAAGAACTAAAGCAGCTAATCTCAATGTCCTCCTATTAATTTCAGCAATAATTTTTAT
CATAATTTAGAATAAATAATGTTTAGTGATGATGCAAATGACAACCATTCTTCTTGCACC
AATACTAGCAGCAACGTTTTTAGTTTAAAAAAAGAATCAAATCCCAGTTTCCGTAAGTAG
TCTTCTTTTAATCTTGATAAAAAATAAAACTCCTCCTAGAACTTTGATAATTGCATACAA
AAGCTTAGAAAATATGAGTCTGACGACTGTAAAAACCAATTGTCTTACGGATTTGCTACC
ACAACTAATGCAAATACTGAATTAAGTCTCTCTAATTAAAACTCCTTTTCATCAGCCATA
AGCACTCCCTTTTCTCGAAATACTAAAAAATAGAATAATGCAACATTTTCAGCTCATTCT
TAGGATTCAAGTTTAGGCTATGAAAGATTCATTCCAACTAGAAAAAATAATAAGATGTTT
ATTAATTTTTAAAATAAAGACTCTTCTGATATGACAAAGAAATCTTCTTAAATAAAAAAT
GACCCCTAAACTGCATGCTATTCCCAAAATAGCAATGAATCTTTCTCAATTGCATCTCTT
TATTAAAAGCATATCTTAGATACTTCAGATAACTCCAAGATTCTCTCTTTTAATGGAAAC
AGACAGTAAAACACTAACTCTGCATTTATGTCCTAACAAAAATCAGGGTTATATTCATAG
TAGTCTATTATGGAATAAGAAAATATTAATGATGAAGATTTCTTTAGGAGTAATGGATAA
CTACCAAGTTAAAGCTCCTTAAGCTTTAAAAAAAAGTAATCTTTAGTTATCACAGATAGT
ACAAAAATCTTAGATGCACCTGGTTTAGAAGATGACTACTACTTGAATTTACTTCATTGG
AGTGCATAAAATGTCATCTCTATTGTACTTAAGAATGAAGTATTTGGCTACAATTATAGT
AATAAAAAAATTTTTAGTATGCAAAAACCTGATAAAAATAACATATATAAATTTACATCT
GTTAAATTTAGCAAGTCTGGCAAGCTGCTGGCAATCGGAGACTCACTTGGAGGTGTATAA
ATTATAGATGCTGAGACTCGTAGAGAAGTAGCTTTCTTTTAAAACCATGAAGATAGAGTA
GCTAGTCTTTCTTGGATAAATGACGAAATTTTAGCAAGTGGTTCAAAAGATAGAAATATT
TATTGTCATGATATACGTGATAAGAATATAGTCCGCAAATATCAAGGACATCGTAATGAA
GTTTGTGGTCTAGAATGGTCATGCGATTAATAAACATTAGCTAGTGGAGGAAACGATGAC
AAATTATTTGTTTGGAATATAGGATACAATCAGCATTAGTATAAATTCTCACAGCATAAA
GCTGCTGTAAAGGCCATTACCTGGAGCCCTCATTAACATGGTTTGCTTGTTTCAGGAGGT
GGCAGTCGTGATAAAACTATTCGTTTTTGGAATATTCATACAGGAAAAGAAGTTGATTGT
ATTGAAACAAGCAGTTAAGTTTGCAGTTTAGCCTTTACTAAGAACACTAATCAATTTGTT
TCTACTCATGGTTATGCAGACAATGAAATATATGTTTGGAAATATCCTAACCCTCAAAAA
GTAAAAATATTCCAAGGCCACTAATAAAGAGTTATTTACATGGCTTTGAGCCCTGATCAA
AAATAAATAGTCACTGGAGCTAGTGATGAGACTCTTCGTTTTTGGGACGCCTTCCCGGAT
GCCCCTTCTTTTAAAGGACCTGAATCAACTCTTAAATTTTCTGATTTAAGATGA



>TTHERM_00825380(gene)
ATCAAATAAAGATAATATCAATAATTTGTTTGTCTGTCAATATATTTTACAATTTGATTT
ATTTAGCGGTACAGAATGATTCTTTTTAAAAAACATCAATAAATTTAATATTTGCAAATG
GTTTGGAGTGTTTTATTTTTAATTAATACTAATAAATAATAATAAAAAAGGATTTCTGTC
AAGCCTTTAATTTTATTTGTCAATAATTAAAAGATATTTATGCAAATAAAAAATATTACA
ATTGCTGAACAAAATCTTAAATAAATTAATCATAATATAAATTCCCGCAAATTGATCGGC
TATCTATCTTCAATATAAATTATTTAAATCATTAAAATTCAAGCAAATTAAACATAAAGA
CAAGATAAAGCGCAACCTATTTACCAGTGGTTTCTAACACAACTAATACAGCTTAACAGT
TTTGAATATCCTCATCTTTTAAAGCATATACAATTTCTTATTTTTTATTGCTAGCCTCTC
CTCAGCTCTTCAATAAATCCTTTCAGACTCCGAAAATCAACTTTTATTATTTCTTAATAA
CATTCCTATTTAATAATTAACTCTATGAGTGAGATATAAATTGAAGAATAACCCTTTTGC
TTTAATATAGGATTAAATGAAAATGAACTAAACTCATCCTTCTGTTCACAAAATATTGAA
TAGGAGCTTTACAAAAAGCAGAATTCTTAAGCTAGTCTCTATTTTTAATCTATTTCTTAG
TAGGATAATACTAGTGACAAGAACTAAAGCAGCTAATCTCAATGTCCTCCTATTAATTTC
AGCAATAATTTTTATCATAATTTAGAATAAATAATGTTTAGTGATGATGCAAATGACAAC
CATTCTTCTTGCACCAATACTAGCAGCAACGTTTTTAGTTTAAAAAAAGAATCAAATCCC
AGTTTCCGTAAGTAGTCTTCTTTTAATCTTGATAAAAAATAAAACTCCTCCTAGAACTTT
GATAATTGCATACAAAAGCTTAGAAAATATGAGTCTGACGACTGTAAAAACCAATTGTCT
TACGGATTTGCTACCACAACTAATGCAAATACTGAATTAAGTCTCTCTAATTAAAACTCC
TTTTCATCAGCCATAAGCACTCCCTTTTCTCGAAATACTAAAAAATAGAATAATGCAACA
TTTTCAGCTCATTCTTAGGATTCAAGTTTAGGCTATGAAAGATTCATTCCAACTAGAAAA
AATAATAAGATGTTTATTAATTTTTAAAATAAAGACTCTTCTGATATGACAAAGAAATCT
TCTTAAATAAAAAATGACCCCTAAACTGCATGCTATTCCCAAAATAGCAATGAATCTTTC
TCAATTGCATCTCTTTATTAAAAGCATATCTTAGATACTTCAGATAACTCCAAGATTCTC
TCTTTTAATGGAAACAGACAGTAAAACACTAACTCTGCATTTATGTCCTAACAAAAATCA
GGGTTATATTCATAGTAGTCTATTATGGAATAAGAAAATATTAATGATGAAGATTTCTTT
AGGAGTAATGGATAACTACCAAGTTAAAGCTCCTTAAGCTTTAAAAAAAAGTAATCTTTA
GTTATCACAGATAGTACAAAAATCTTAGATGCACCTGGTTTAGAAGATGACTACTACTTG
AATTTACTTCATTGGAGTGCATAAAATGTCATCTCTATTGTACTTAAGAATGAAGTATTT
GGCTACAATTATAGTAATAAAAAAATTTTTAGTATGCAAAAACCTGATAAAAATAACATA
TATAAATTTACATCTGTTAAATTTAGCAAGTCTGGCAAGCTGCTGGCAATCGGAGACTCA
CTTGGAGGTGTATAAATTATAGATGCTGAGACTCGTAGAGAAGTAGCTTTCTTTTAAAAC
CATGAAGATAGAGTAGCTAGTCTTTCTTGGATAAATGACGAAATTTTAGCAAGTGGTTCA
AAAGATAGAAATATTTATTGTCATGATATACGTGATAAGAATATAGTCCGCAAATATCAA
GGACATCGTAATGAAGTTTGTGGTCTAGAATGGTCATGCGATTAATAAACATTAGCTAGT
GGAGGAAACGATGACAAATTATTTGTTTGGAATATAGGATACAATCAGCATTAGTATAAA
TTCTCACAGCATAAAGCTGCTGTAAAGGCCATTACCTGGAGCCCTCATTAACATGGTTTG
CTTGTTTCAGGAGGTGGCAGTCGTGATAAAACTATTCGTTTTTGGAATATTCATACAGGA
AAAGAAGTTGATTGTATTGAAACAAGCAGTTAAGTTTGCAGTTTAGCCTTTACTAAGAAC
ACTAATCAATTTGTTTCTACTCATGGTTATGCAGACAATGAAATATATGTTTGGAAATAT
CCTAACCCTCAAAAAGTAAAAATATTCCAAGGCCACTAATAAAGAGTTATTTACATGGCT
TTGAGCCCTGATCAAAAATAAATAGTCACTGGAGCTAGTGATGAGACTCTTCGTTTTTGG
GACGCCTTCCCGGATGCCCCTTCTTTTAAAGGACCTGAATCAACTCTTAAATTTTCTGAT
TTAAGATGATGAAAAATAGAAAAAAACATTTAAAAATTCAACGAAAAAACAAACAACAAC
TCAAAGAGCTTATATTACAAATTTCTCATTTGAAAACTCTCTATTTATAATACTAAATAA
AAGATCTTATCCTTCTATTCAATTTTCAAATTACTCTAACCTTATTTAATCATATTAACA
AATTTAATTATATAAATAAATAAATATATTTCATACGTTTAAATTTTGTAACTATATAAA
TTATAAGTAAGTACTATACTATT



>TTHERM_00825380(protein)
MILFKKHQQIQYLQMVWSVLFLINTNKQQQKRISVKPLILFVNNQKIFMQIKNITIAEQN
LKQINHNINSRKLIGYLSSIQIIQIIKIQANQTQRQDKAQPIYQWFLTQLIQLNSFEYPH
LLKHIQFLIFYCQPLLSSSINPFRLRKSTFIISQQHSYLIINSMSEIQIEEQPFCFNIGL
NENELNSSFCSQNIEQELYKKQNSQASLYFQSISQQDNTSDKNQSSQSQCPPINFSNNFY
HNLEQIMFSDDANDNHSSCTNTSSNVFSLKKESNPSFRKQSSFNLDKKQNSSQNFDNCIQ
KLRKYESDDCKNQLSYGFATTTNANTELSLSNQNSFSSAISTPFSRNTKKQNNATFSAHS
QDSSLGYERFIPTRKNNKMFINFQNKDSSDMTKKSSQIKNDPQTACYSQNSNESFSIASL
YQKHILDTSDNSKILSFNGNRQQNTNSAFMSQQKSGLYSQQSIMEQENINDEDFFRSNGQ
LPSQSSLSFKKKQSLVITDSTKILDAPGLEDDYYLNLLHWSAQNVISIVLKNEVFGYNYS
NKKIFSMQKPDKNNIYKFTSVKFSKSGKLLAIGDSLGGVQIIDAETRREVAFFQNHEDRV
ASLSWINDEILASGSKDRNIYCHDIRDKNIVRKYQGHRNEVCGLEWSCDQQTLASGGNDD
KLFVWNIGYNQHQYKFSQHKAAVKAITWSPHQHGLLVSGGGSRDKTIRFWNIHTGKEVDC
IETSSQVCSLAFTKNTNQFVSTHGYADNEIYVWKYPNPQKVKIFQGHQQRVIYMALSPDQ
KQIVTGASDETLRFWDAFPDAPSFKGPESTLKFSDLR