Identifiers and Description

Gene Model Identifier

TTHERM_00837980

Standard Name

CDK6 (Cyclin Dependent Kinase 6)

Aliases

PreTt17811 | 146.m00112 | 3743.m00043

Description

CDK6 Protein kinase domain containing protein; sequence similarity to the CDKL protein kinase family; involved in DNA replication; hypothetical protein

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Cellular Component

• aleurone grain membrane (IEA) | GO:0032578
• alpha6-beta4 integrin-Shc-Grb2 complex (IEA) | GO:0070333
• AMPA glutamate receptor complex (IEA) | GO:0032281
• CURI complex (IEA) | GO:0032545
• Dbf4-dependent protein kinase complex (IEA) | GO:0031431
• lysosomal HOPS complex (IEA) | GO:1902501
• multivesicular body (IEA) | GO:0005771
• peptidase complex (IEA) | GO:1905368
• vacuolar membrane (IEA) | GO:0005774

Molecular Function

• (Z)-gamma-bisabolene synthase activity (IEA) | GO:0052683
• 11-deoxycorticosterone binding (IEA) | GO:1903878
• 17alpha-hydroxyprogesterone binding (IEA) | GO:1903880
• 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity (IEA) | GO:0008413
• alpha-humulene synthase activity (IEA) | GO:0080017
• aromatase activity (IEA) | GO:0008402
• axon guidance receptor activity (IEA) | GO:0008046
• catechol O-methyltransferase activity (IEA) | GO:0016206
• corticosterone binding (IEA) | GO:1903875
• growth hormone-releasing hormone receptor activity (IEA) | GO:0016520
• L-gamma-glutamyl-L-propargylglycine hydroxylase activity (IEA) | GO:0062148
• lipopolysaccharide heptosyltransferase activity (IEA) | GO:0008920
• obsolete aminoacetone:oxygen oxidoreductase(deaminating) activity (IEA) | GO:0052594
• obsolete aspartic-type signal peptidase activity (IEA) | GO:0009049
• obsolete sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity (IEA) | GO:0052591
• obsolete sodium-transporting two-sector ATPase activity (IEA) | GO:0015443
• obsolete tryptamine:oxygen oxidoreductase (deaminating) activity (IEA) | GO:0052593
• oxidoreductase activity, acting on CH or CH2 groups, with an iron-sulfur protein as acceptor (IEA) | GO:0052592
• phosphatidylcholine:cardiolipin O-linoleoyltransferase activity (IEA) | GO:0032577
• phosphatidylserine decarboxylase activity (IEA) | GO:0004609
• pituitary adenylate cyclase activating polypeptide activity (IEA) | GO:0016521
• Pup ligase activity (IEA) | GO:0061664
• sphingomyelin phosphodiesterase activity (IEA) | GO:0004767
• sterol 14-demethylase activity (IEA) | GO:0008398
• type 4 neuropeptide Y receptor binding (IEA) | GO:0031844
• UFM1 ligase activity (IEA) | GO:0061666

Biological Process

• 3-keto-sphinganine metabolic process (IEA) | GO:0006666
• alkaloid biosynthetic process (IEA) | GO:0009821
• aminoacyl-tRNA metabolism involved in translational fidelity (IEA) | GO:0106074
• cell wall modification involved in fruit ripening (IEA) | GO:0009829
• cellular response to ammonia (IEA) | GO:1903718
• cellular response to hydroxyurea (IEA) | GO:0072711
• detection of stimulus involved in Dma1-dependent checkpoint (IEA) | GO:1902419
• detection of stimulus involved in sensory perception of pain (IEA) | GO:0062149
• dichotomous subdivision of terminal units involved in lung branching (IEA) | GO:0060448
• endomitotic cell cycle (IEA) | GO:0007113
• evoked neurotransmitter secretion (IEA) | GO:0061670
• female courtship behavior (IEA) | GO:0008050
• fibroblast growth factor receptor signaling pathway (IEA) | GO:0008543
• galactose to glucose-1-phosphate metabolic process (IEA) | GO:0061612
• glycolytic process from glycerol (IEA) | GO:0061613
• guanine transmembrane transport (IEA) | GO:1903716
• heme A biosynthetic process (IEA) | GO:0006784
• heme biosynthetic process (IEA) | GO:0006783
• intraciliary retrograde transport (IEA) | GO:0035721
• L-alanine catabolic process (IEA) | GO:0042853
• maintenance of left sidedness (IEA) | GO:0061969
• maintenance of right sidedness (IEA) | GO:0061970
• mannosyl-inositol phosphorylceramide metabolic process (IEA) | GO:0006675
• mitochondrial membrane organization (IEA) | GO:0007006
• mitotic cytokinetic cell separation (IEA) | GO:1902409
• negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process (IEA) | GO:1902647
• negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process (IEA) | GO:1902642
• negative regulation of complement-dependent cytotoxicity (IEA) | GO:1903660
• negative regulation of double-strand break repair via nonhomologous end joining (IEA) | GO:2001033
• negative regulation of epithelial cell-cell adhesion involved in epithelium migration (IEA) | GO:1903682
• negative regulation of L-glutamine biosynthetic process (IEA) | GO:0062133
• negative regulation of natural killer cell proliferation involved in immune response (IEA) | GO:0032821
• negative regulation of PERK-mediated unfolded protein response (IEA) | GO:1903898
• negative regulation of phytoalexin metabolic process (IEA) | GO:0052321
• negative regulation of renal water transport (IEA) | GO:2001152
• negative regulation of vasculogenesis (IEA) | GO:2001213
• neutral lipid metabolic process (IEA) | GO:0006638
• obsolete activation of MAPK activity (IEA) | GO:0000187
• obsolete cellular response to Dizocilpine (IEA) | GO:1905107
• obsolete cellular response to ouabain (IEA) | GO:1905105
• obsolete histone succinylation (IEA) | GO:0106077
• obsolete multi-organism cellular localization (IEA) | GO:1902581
• obsolete negative regulation by organism of symbiont T-cell mediated immune response (IEA) | GO:0052474
• obsolete negative regulation of response to extracellular stimulus (IEA) | GO:0032105
• obsolete positive regulation of nucleic acid-templated transcription (IEA) | GO:1903508
• obsolete positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response (IEA) | GO:0006990
• obsolete regulation of apurinic/apyrimidinic endodeoxyribonuclease activity (IEA) | GO:0052721
• obsolete regulation of glucose-6-phosphatase activity (IEA) | GO:0032114
• obsolete regulation of histone H3-K27 methylation (IEA) | GO:0061085
• obsolete sodium/potassium transport (IEA) | GO:0006815
• ommochrome biosynthetic process (IEA) | GO:0006727
• P granule disassembly (IEA) | GO:1903864
• phagocytosis (IEA) | GO:0006909
• plant-type cell wall modification (IEA) | GO:0009827
• positive regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process (IEA) | GO:1902643
• positive regulation of antifungal innate immune response (IEA) | GO:1905036
• positive regulation of deacetylase activity (IEA) | GO:0090045
• positive regulation of glutamate neurotransmitter secretion in response to membrane depolarization (IEA) | GO:0061646
• positive regulation of glyoxylate cycle (IEA) | GO:2000876
• positive regulation of hindgut contraction (IEA) | GO:0060450
• positive regulation of inner ear receptor cell differentiation (IEA) | GO:2000982
• positive regulation of oxidative phosphorylation (IEA) | GO:1903862
• positive regulation of peroxisome proliferator activated receptor signaling pathway (IEA) | GO:0035360
• positive regulation of phospholipid translocation (IEA) | GO:0061092
• positive regulation of protein autoubiquitination (IEA) | GO:1902499
• positive regulation of Rap GTPase activity (IEA) | GO:0032854
• positive regulation of renal water transport (IEA) | GO:2001153
• positive regulation of response to water deprivation (IEA) | GO:1902584
• positive regulation of wound healing, spreading of epidermal cells (IEA) | GO:1903691
• priming of cellular response to stress (IEA) | GO:0080136
• propan-2-ol biosynthetic process (IEA) | GO:1902640
• protein localization to old growing cell tip (IEA) | GO:1903858
• regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process (IEA) | GO:1902646
• regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process (IEA) | GO:1902641
• regulation of atrial cardiac muscle cell membrane depolarization (IEA) | GO:0060371
• regulation of cellular glucuronidation (IEA) | GO:2001029
• regulation of cellular respiration (IEA) | GO:0043457
• regulation of chitin metabolic process (IEA) | GO:0032882
• regulation of complement-dependent cytotoxicity (IEA) | GO:1903659
• regulation of cytokinin dehydrogenase activity (IEA) | GO:1903856
• regulation of interleukin-27-mediated signaling pathway (IEA) | GO:0070107
• regulation of L-arginine import into cell (IEA) | GO:1902826
• regulation of membrane lipid metabolic process (IEA) | GO:1905038
• regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process (IEA) | GO:1902962
• regulation of pentose-phosphate shunt (IEA) | GO:0043456
• regulation of PERK-mediated unfolded protein response (IEA) | GO:1903897
• regulation of phosphatidylcholine biosynthetic process (IEA) | GO:2001245
• regulation of phosphorus utilization (IEA) | GO:0006795
• regulation of respiratory gaseous exchange by nervous system process (IEA) | GO:0002087
• regulation of RNA binding (IEA) | GO:1905214
• regulation of vein smooth muscle contraction (IEA) | GO:0062086
• release of sequestered calcium ion into cytosol by endoplasmic reticulum (IEA) | GO:1903514
• response to curcumin (IEA) | GO:1904643
• response to iron(III) ion (IEA) | GO:0010041
• response to transition metal nanoparticle (IEA) | GO:1990267
• selenocysteine biosynthetic process (IEA) | GO:0016260
• selenocysteine catabolic process (IEA) | GO:0016261
• single-organism intracellular transport (IEA) | GO:1902582
• sterol regulatory element binding protein cleavage involved in ER-nuclear sterol response pathway (IEA) | GO:0006992
• T-helper 2 cell lineage commitment (IEA) | GO:0002297
• tertiary alcohol biosynthetic process (IEA) | GO:1902645
• vacuolar acidification (IEA) | GO:0007035
• viral translational frameshifting (IEA) | GO:0075523

Domains

No Data fetched for Domains

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

No Data fetched for Homologs

General Information

No Data fetched for General Information

Associated Literature

1. Ref:16933976: Eisen JA, Coyne RS, Wu M, Wu D, Thiagarajan M, Wortman JR, Badger JH, Ren Q, Amedeo P, Jones KM, Tallon LJ, Delcher AL, Salzberg SL, Silva JC, Haas BJ, Majoros WH, Farzad M, Carlton JM, Smith RK, Garg J, Pearlman RE, Karrer KM, Sun L, Manning G, Elde NC, Turkewitz AP, Asai DJ, Wilkes DE, Wang Y, Cai H, Collins K, Stewart BA, Lee SR, Wilamowska K, Weinberg Z, Ruzzo WL, Wloga D, Gaertig J, Frankel J, Tsao CC, Gorovsky MA, Keeling PJ, Waller RF, Patron NJ, Cherry JM, Stover NA,

Sequences

>TTHERM_00837980(coding)
ATGAATTATGAAATTTAAAATTAAGAGAGTTACTATTTGTATCTATCAAGCACATATGGA
GCAGAGTTTATTGAAACTAAGCTTTCCTTACATAGCAATATTAGAAAATTAAAATTAGTA
TTAAATACAAATGATAAGGAAGGTATAAATTAGTTAGGATTGCAACTTACAAATTTAAAT
CATTTACTAGAATTAACCATCATTATTTAAGAAGAGAGTTGCTTTAATGAAAACATTTTA
CAAGATTTTTTTTAATATTTCTAATAACTGAAAAATTTAGTCAAATTGGAAGTAAATGTT
GCTAGATAAAGCCCCTTTTAAGAATAAAGATCTTCATATTTATCTAACGCTATTTAAAAT
TTAGTAAATTTAGAGAGTCTTATTATAAATTTCGAAGGAGAAAATAACCTATCTTAAAAT
GGAGCTTCTGCTATTGGATATTGCTTAAGATATTTGAAGAAACTCAATAATTTAAATTTA
TAAATTGGTTATGATTTTATAGGAAAATAAGGATGCGAAAAATTAGCTGATGGAATTGCT
CATCTTATTAATTTACAATAATTGACTATTTCTATTAGAGAGTATAATTTAATAGAAAGT
GGATCTATTTAGCTTGGAAAAAGCTTAGAGAATTTAACTAATTTGAGCTATTTAAAACTA
AATATAGAAATGGATAACTAAATAGAATCTCAAGGTGCTATAGCTTTAGCAAAAGGAATT
TCAAGTCTTACTAATTTGAATCGTTTGGAACTCTTAATAGGTTATAATAATAATATTGGC
TAGTAGGGAGCAATTAGCCTAGGAAATGCGCTTATAAAATTGAAAAGTTTAGACTATCTT
GAACTAATTATTTCTGGTGGAAATGAAATTTAATTCAAAGGTGCTTAGGGTATTGCAGAA
GGTTTAAAGGCTTTAAAAAATCTAAAAGATCTTAAATTAAATATTCTAGGAGATAATTAA
TTAGGATAAAAAGGTTCTACTTCGATAATCAAATCATTATCTTATCTTAAAAATCTAGAA
AACTTAGAATTTGATATTGGTGAAGTTGATTATATTGAAAAAGAAGGGGCAATACAACTT
GGAAAGTCAATTTAACAAATGAAAAATTTAAATAATTTAAATTTATGGATCCATGACTGT
AATGATATTTAGCAAGGAGGCGCTAAATCAATTGGCTAAGGATTATCTCATCTTTCAAAT
TTGAAATTTCTTAATTTGAATATCTTTTCTGTAAATCAAATAGGCCCTAAAGGTATTCAA
GCAATAGCAAATGGTATAAAATGTTCAAAAAACATGGAGAGTCTATCTCTGTGGATAGAT
CATGATAACTAAATAGGTAGTTAAGGATGTATCTTTATTGGAGAGTCACTATGTCATTTA
AAAGATTTAAAAACTTTAAACATTGATATTGGTGTTTATTCAAAAGTAGGGAAAGAGGGA
ATAATAGGATTATCTCAGTGCTTTAAATATCTCAATTAATTATAAGACCTAAATTTTAGC
ATAAAAGGTTATAATAATTTGACATAAGAAGGGTTTTAATAATTCTCAATCAATATGAAA
AGTTTAGTCAATTTAAAAATATTAGGATTATACTTTGGTAGCAGAAATTAAATAGGTGGG
TAAGGAATGAGTTATTTAGGTCAATAGCTTTTACATTTATAAAATTTAAATAAGTTTTCA
CTTGGTTTAGGAGAAGAAAATAAATTATCTGAAAATTCTCTAAAAAATTTTGGTGAAAGT
TTTAATCATATAAATAGTTTAACTCATATTGATTTAGATATTTATAAACATAATTTGAAA
AATAATGATTTCGGGAATATAGGAAATGCTTTGAGTATGTGCAAAAAACTTTAATTCCTA
AAAATAAAAGTAGATTAAGAACATTAAATAACTTAAAACAACATAAAATTATTTGCTAAT
AACCTCAGTTAGAATAAAACTGTCATTTAAATTAAATATTCTCTTAATTTGGATAGAGAG
GACCCAGACGATTATGGAAATTAAGATGAAGAGGATGAGGAAATAGAAGATGATCTTGAA
GAGGAAAATAATGAAATTTTAGATGAAGAGAATAGCTTATAGAATGACTAAGTAAAAGAA
GAAGATGAAGATATAGACAAAGAAGGCGATGATATGAAAGAAGATGAAAACTTATCAGAA
AATGAAGGCAATTATCAAAAAGATGATGAAGAATTTGATAAAGAAGATTTGGAAAATATG
GATATATAAGAATTTTAATAGGATATGAGTTATTTAGGAAACCAAAACAGTCAAAGTGAG
ATATCAAATTAACAATAAATTTAGGATTTAGATGCTTTTGCTAAAAAATTATTTATAAGA
AAAATAAAATAATTAGTTAATTTAATTCATTGA

>TTHERM_00837980(gene)
TTACAAGTAGCTTATTAGCTGCAGAAAAAATATGCCACAAATAGCAATAAAAACTATAAA
TTTTCATCAAAAGATATTTTAATTTAAATATCTTTTATCTACTTAATTGGATTTCTAAAT
TGTGTGAACAATAAATTAAATAAATAAATTTAAGTTATATTCATAACAAAGATAAATCAA
ATGAATTATGAAATTTAAAATTAAGAGAGTTACTATTTGTATCTATCAAGCACATATGGA
GCAGAGTTTATTGAAACTAAGCTTTCCTTACATAGCAATATTAGAAAATTAAAATTAGTA
TTAAATACAAATGATAAGGAAGGTATAAATTAGTTAGGATTGCAACTTACAAATTTAAAT
CATTTACTAGAATTAACCATCATTATTTAAGAAGAGAGTTGCTTTAATGAAAACATTTTA
CAAGATTTTTTTTAATATTTCTAATAACTGAAAAATTTAGTCAAATTGGAAGTAAATGTT
GCTAGATAAAGCCCCTTTTAAGAATAAAGATCTTCATATTTATCTAACGCTATTTAAAAT
TTAGTAAATTTAGAGAGTCTTATTATAAATTTCGAAGGAGAAAATAACCTATCTTAAAAT
GGAGCTTCTGCTATTGGATATTGCTTAAGATATTTGAAGAAACTCAATAATTTAAATTTA
TAAATTGGTTATGATTTTATAGGAAAATAAGGATGCGAAAAATTAGCTGATGGAATTGCT
CATCTTATTAATTTACAATAATTGACTATTTCTATTAGAGAGTATAATTTAATAGAAAGT
GGATCTATTTAGCTTGGAAAAAGCTTAGAGAATTTAACTAATTTGAGCTATTTAAAACTA
AATATAGAAATGGATAACTAAATAGAATCTCAAGGTGCTATAGCTTTAGCAAAAGGAATT
TCAAGTCTTACTAATTTGAATCGTTTGGAACTCTTAATAGGTTATAATAATAATATTGGC
TAGTAGGGAGCAATTAGCCTAGGAAATGCGCTTATAAAATTGAAAAGTTTAGACTATCTT
GAACTAATTATTTCTGGTGGAAATGAAATTTAATTCAAAGGTGCTTAGGGTATTGCAGAA
GGTTTAAAGGCTTTAAAAAATCTAAAAGATCTTAAATTAAATATTCTAGGAGATAATTAA
TTAGGATAAAAAGGTTCTACTTCGATAATCAAATCATTATCTTATCTTAAAAATCTAGAA
AACTTAGAATTTGATATTGGTGAAGTTGATTATATTGAAAAAGAAGGGGCAATACAACTT
GGAAAGTCAATTTAACAAATGAAAAATTTAAATAATTTAAATTTATGGATCCATGACTGT
AATGATATTTAGCAAGGAGGCGCTAAATCAATTGGCTAAGGATTATCTCATCTTTCAAAT
TTGAAATTTCTTAATTTGAATATCTTTTCTGTAAATCAAATAGGCCCTAAAGGTATTCAA
GCAATAGCAAATGGTATAAAATGTTCAAAAAACATGGAGAGTCTATCTCTGTGGATAGAT
CATGATAACTAAATAGGTAGTTAAGGATGTATCTTTATTGGAGAGTCACTATGTCATTTA
AAAGATTTAAAAACTTTAAACATTGATATTGGTGTTTATTCAAAAGTAGGGAAAGAGGGA
ATAATAGGATTATCTCAGTGCTTTAAATATCTCAATTAATTATAAGACCTAAATTTTAGC
ATAAAAGGTTATAATAATTTGACATAAGAAGGGTTTTAATAATTCTCAATCAATATGAAA
AGTTTAGTCAATTTAAAAATATTAGGATTATACTTTGGTAGCAGAAATTAAATAGGTGGG
TAAGGAATGAGTTATTTAGGTCAATAGCTTTTACATTTATAAAATTTAAATAAGTTTTCA
CTTGGTTTAGGAGAAGAAAATAAATTATCTGAAAATTCTCTAAAAAATTTTGGTGAAAGT
TTTAATCATATAAATAGTTTAACTCATATTGATTTAGATATTTATAAACATAATTTGAAA
AATAATGATTTCGGGAATATAGGAAATGCTTTGAGTATGTGCAAAAAACTTTAATTCCTA
AAAATAAAAGTAGATTAAGAACATTAAATAACTTAAAACAACATAAAATTATTTGCTAAT
AACCTCAGTTAGAATAAAACTGTCATTTAAATTAAATATTCTCTTAATTTGGATAGAGAG
GACCCAGACGATTATGGAAATTAAGATGAAGAGGATGAGGAAATAGAAGATGATCTTGAA
GAGGAAAATAATGAAATTTTAGATGAAGAGAATAGCTTATAGAATGACTAAGTAAAAGAA
GAAGATGAAGATATAGACAAAGAAGGCGATGATATGAAAGAAGATGAAAACTTATCAGAA
AATGAAGGCAATTATCAAAAAGATGATGAAGAATTTGATAAAGAAGATTTGGAAAATATG
GATATATAAGAATTTTAATAGGATATGAGTTATTTAGGAAACCAAAACAGTCAAAGTGAG
ATATCAAATTAACAATAAATTTAGGATTTAGATGCTTTTGCTAAAAAATTATTTATAAGA
AAAATAAAATAATTAGTTAATTTAATTCATTGAAATTTAATTTGTGAAATGCATTATGTA
TGATTCTTTAAATATTTTGCTTTTTATCA

>TTHERM_00837980(protein)
MNYEIQNQESYYLYLSSTYGAEFIETKLSLHSNIRKLKLVLNTNDKEGINQLGLQLTNLN
HLLELTIIIQEESCFNENILQDFFQYFQQLKNLVKLEVNVARQSPFQEQRSSYLSNAIQN
LVNLESLIINFEGENNLSQNGASAIGYCLRYLKKLNNLNLQIGYDFIGKQGCEKLADGIA
HLINLQQLTISIREYNLIESGSIQLGKSLENLTNLSYLKLNIEMDNQIESQGAIALAKGI
SSLTNLNRLELLIGYNNNIGQQGAISLGNALIKLKSLDYLELIISGGNEIQFKGAQGIAE
GLKALKNLKDLKLNILGDNQLGQKGSTSIIKSLSYLKNLENLEFDIGEVDYIEKEGAIQL
GKSIQQMKNLNNLNLWIHDCNDIQQGGAKSIGQGLSHLSNLKFLNLNIFSVNQIGPKGIQ
AIANGIKCSKNMESLSLWIDHDNQIGSQGCIFIGESLCHLKDLKTLNIDIGVYSKVGKEG
IIGLSQCFKYLNQLQDLNFSIKGYNNLTQEGFQQFSINMKSLVNLKILGLYFGSRNQIGG
QGMSYLGQQLLHLQNLNKFSLGLGEENKLSENSLKNFGESFNHINSLTHIDLDIYKHNLK
NNDFGNIGNALSMCKKLQFLKIKVDQEHQITQNNIKLFANNLSQNKTVIQIKYSLNLDRE
DPDDYGNQDEEDEEIEDDLEEENNEILDEENSLQNDQVKEEDEDIDKEGDDMKEDENLSE
NEGNYQKDDEEFDKEDLENMDIQEFQQDMSYLGNQNSQSEISNQQQIQDLDAFAKKLFIR
KIKQLVNLIH