Identifiers and Description

Gene Model Identifier

TTHERM_00859260

Standard Name

EF1BL1 (Elongation Factor 1 Beta Like 1)

Aliases

PreTt09088 | 152.m00108

Description

EF-1 guanine nucleotide exchange domain protein; EF-1 guanine nucleotide exchange domain containing protein; involved in guanine nucleotide exchange to activate EF1A from its inactive (GDP) form to its active (GTP) form so that it can readily associate with an aminoacyl-tRNA

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Cellular Component

• cytoplasm (IDA) | GO:0005737
• eukaryotic translation elongation factor 1 complex (IEA) | GO:0005853

Molecular Function

• guanyl-nucleotide exchange factor activity (IDA) | GO:0005085
• translation elongation factor activity (IEA) | GO:0003746

Biological Process

• translation (IDA) | GO:0006412
• translational elongation (IEA) | GO:0006414

Domains

• ( PF00736 ) EF-1 guanine nucleotide exchange domain
• ( TIGR00489 ) translation elongation factor aEF-1 beta

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_07206.1	2.0005752503420762e-105
	Description: EF-1 guanine nucleotide exchange domain-containing protein (226 aa)
WormBase	WBGene00017981	2.0005752503420762e-105
	Description: locus:figl-1 Fidgetin-like protein 1 status:Partially_confirmed UniProt:O16299 protein_id:CCD68481.1
Oxytricha	Contig19220.0.g56	9.001422350855153e-28
	Description: EF-1 guanine nucleotide exchange domain
WormBase	WBGene00018846	3.0002687256732656e-20
	Description: locus:eef-1B.1 Probable elongation factor 1-beta/1-delta 1 status:Confirmed UniProt:P34460 protein_id:CCD63459.1
Tetrahymena borealis	EI9_15261.1	3.0002687256732656e-20
	Description: hypothetical protein (790 aa)
DictyBase	DDB_G0284035	0.000000000000001999258566166494
	Description: efa1B on chromosome: 4 position 1535647 to 1536451
WormBase	WBGene00011935	0.000000000000001999258566166494
	Description: locus:scrm-1 status:Confirmed UniProt:O45799 protein_id:CAB04754.2
SGD	YAL003W	0.0000000000000030004923591262316
	Description: EFB1 Translation elongation factor 1 beta; stimulates nucleotide exchange to regenerate EF-1 alpha-GTP for the next elongation cycle; part of the EF-1 complex, which facilitates binding of aminoacyl-tRNA to the ribosomal A site
Stentor Coeruleus	SteCoe_13681	0.000000000013887943864964021
	Description: None

General Information

No Data fetched for General Information

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_00859260(coding)
ATGAATAAAGAAATAGTATATTTATAATATGAGATGGATTGGTTGCTTGGTTGCTTGTTT
AATAGATTGATAGAAACTTAAAAAACTATAAATTTCTTTTTAAGTCAATTCCTTCTTTTT
TTCCATTCGATAAACAAATATCTTTTTTTTTTTGAGACAATCAAAAAAATATATATATTT
TTGTTTGTTTGCTTTTTTAGATTATTTTTAGATTTGCATTTGTACGTATTTTTAATATAC
ATTAAAAAATAAATTCTCTGGGAAAAGATATATAAAGTAAATTTAATAAATTATTATCAA
AAACTAAAAAACAAAAAGCAAAAAACAAACCAATTCTCTAAAATGACTTTCTCTGCTACC
GACCTCCCCACCCTCGAAAAGCACTTAGCTGCCCACACCTACCTTTCCGGTACTGATAAG
CCCGCTAAGATTGATGCTTAAATTGCCACCGAACTCAAGGATAAGAAGGTTGCCCTCAAC
GCCGCCACCCACCCCAACGTCTATGCCTGGTTCAGCTTCATCGGTTTATTCACCCCCGAA
GCTCAAAATACCTGGGCTGATGTTGCTCCCGTCGCCGTCCCCGTTGCTGCCAAGAAGGAA
GCCAAGAAGGAAACCAAGACCGACGATGTCGATCTTTTCGGTGATGATGATGAAGAAGAT
GCTGAAGCTGAAGCTTTGAGAGAAAAGAAGAGACTCGAAGCCGTCGCTGCCAAGGAAGCT
AGAGATGGTAAGAAGAAGAAGGCTATTGCCAAGACTATCCTCGTCTTCAACGTCAAGGTC
TTCGAAGCTGAATAAGACTTAGACGCTTTGGCCAAGAAGATCTACGAAACCATCCAACTC
GACGGTTTGGTCTGGAACAAGGAACACAAGAAGATCCCCGTTGCCTTCGGTGTCTTCATG
CTCCAAATGGGTTGCATCATTGAAGACGATAAGGTCAACACCGACAGTATCTTCGAACCC
ATCCAATCTTGGGAAGATGAAGTCCAATCCGTTGATGTTGAAACCATGCAAAAACTTTGA

>TTHERM_00859260(gene)
ATGAATAAAGAAATAGTATATTTATAATATGAGATGGATTGGTTGCTTGGTTGCTTGTTT
AATAGATTGATAGAAACTTAAAAAACTATAAATTTCTTTTTAAGTCAATTCCTTCTTTTT
TTCCATTCGATAAACAAATATCTTTTTTTTTTTGAGACAATCAAAAAAATATATATATTT
TTGTTTGTTTGCTTTTTTAGATTATTTTTAGATTTGCATTTGTACGTATTTTTAATATAC
ATTAAAAAATAAATTCTCTGGGAAAAGATATATAAAGTAAATTTAATAAATTATTATCAA
AAACTAAAAAACAAAAAGCAAAAAACAAACCAATTCTCTAAAATGACTTTCTCTGCTACC
GACCTCCCCACCCTCGAAAAGCACTTAGCTGCCCACACCTACCTTTCCGGTACTGATAAG
CCCGCTAAGATTGATGCTTAAATTGCCACCGAACTCAAGGGTAACTTATTTATTTACTAA
TCATTATCTCCCTCACATCCATCCATCCATTCACTTACTTACTCATTCACTCATTATTCG
GTGATCTCTTCCACTTAGACTTTTTTCTCTTAGAAAATTTTAAAATAATGGATTGAAGAA
AATAAACTTCTTTGAAATTTTTTAGTCAATATTGCTCTCTTAAAACACACTCAAGTTTTC
ATTAATAATTTATTAATATTATTTTAAATATATAGATAAGAAGGTTGCCCTCAACGCCGC
CACCCACCCCAACGTCTATGCCTGGTTCAGCTTCATCGGTTTATTCACCCCCGAAGCTCA
AAATACCTGGGCTGATGTTGCTCCCGTCGCCGTCCCCGTTGCTGCCAAGAAGGAAGCCAA
GAAGGAAACCAAGACCGTAAGAAATTTTTCTTTTATCAAGCAATAACAACAATGGAAATC
ATTTTAATTCTACCCATAACTCCTATAGCTTATTTACTTACTAACTTACAAAAGATAAAA
TGAATAAAAATAAATTTTCTTGATATATAAATAAATACCTATTCCCCCTTTGATATATAT
ATCGGAAAACATGCAAGCGACAAGCAAAGATAGGATTTTCATTGACCATAGAACCATTTT
TCTAAATTATTGTTGTATATAAATAGGACGATGTCGATCTTTTCGGTGATGATGATGAAG
AAGATGCTGAAGCTGAAGCTTTGAGAGAAAAGAAGAGACTCGAAGCCGTCGCTGCCAAGG
AAGCTAGAGATGGTAAGAAGAAGAAGGCTATTGCCAAGACTATCCTCGTCTTCAACGTCA
AGGTCTTCGAAGCTGAATAAGACTTAGACGCTTTGGCCAAGAAGATCTACGAAACCATCC
AACTCGACGGTTTGGTCTGGAACAAGGAACACAAGAAGATCCCCGTTGCCTTCGGTGTCT
TCATGCTCCAAATGGGTTGCATCATTGAAGACGATAAGGTCAACACCGACAGTATCTTCG
AACCCATCCAATCTTGGGAAGATGAAGTCCAATCCGTTGATGTTGAAACCATGCAAAAAC
TTTGA

>TTHERM_00859260(protein)
MNKEIVYLQYEMDWLLGCLFNRLIETQKTINFFLSQFLLFFHSINKYLFFFETIKKIYIF
LFVCFFRLFLDLHLYVFLIYIKKQILWEKIYKVNLINYYQKLKNKKQKTNQFSKMTFSAT
DLPTLEKHLAAHTYLSGTDKPAKIDAQIATELKDKKVALNAATHPNVYAWFSFIGLFTPE
AQNTWADVAPVAVPVAAKKEAKKETKTDDVDLFGDDDEEDAEAEALREKKRLEAVAAKEA
RDGKKKKAIAKTILVFNVKVFEAEQDLDALAKKIYETIQLDGLVWNKEHKKIPVAFGVFM
LQMGCIIEDDKVNTDSIFEPIQSWEDEVQSVDVETMQKL