Identifiers and Description

Gene Model Identifier

TTHERM_00864890

Standard Name

UDH12 (UvrD/REP-family DNA helicase 12)

Aliases

PreTt29119 | 154.m00077 | 3751.m00423 | REP4

Description

UDH12 UvrD/REP helicase family protein; UvrD/REP helicase family protein; DNA helicase, UvrD/REP type

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Cellular Component

• ionotropic glutamate receptor complex (IEA) | GO:0008328
• obsolete integral component of mitochondrial membrane (IEA) | GO:0032592
• serine/threonine protein kinase complex (IEA) | GO:1902554

Molecular Function

• 11-deoxycorticosterone binding (IEA) | GO:1903878
• 17alpha-hydroxyprogesterone binding (IEA) | GO:1903880
• 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity (IEA) | GO:0008413
• amino acid:monoatomic cation symporter activity (IEA) | GO:0005416
• icosanoid receptor activity (IEA) | GO:0004953
• L-arabinokinase activity (IEA) | GO:0009702
• obsolete sodium-transporting two-sector ATPase activity (IEA) | GO:0015443
• phosphatidylinositol-3-phosphate binding (IEA) | GO:0032266
• phosphatidylserine decarboxylase activity (IEA) | GO:0004609
• phosphoenolpyruvate carboxykinase (GTP) activity (IEA) | GO:0004613
• sphingomyelin phosphodiesterase activity (IEA) | GO:0004767
• tRNA threonylcarbamoyladenosine dehydratase (IEA) | GO:0061503
• type 4 neuropeptide Y receptor binding (IEA) | GO:0031844

Biological Process

• cell wall modification involved in fruit ripening (IEA) | GO:0009829
• glycolytic process from mannose through fructose-6-phosphate (IEA) | GO:0061619
• heme A biosynthetic process (IEA) | GO:0006784
• heme biosynthetic process (IEA) | GO:0006783
• immunoglobulin heavy chain V-D-J recombination (IEA) | GO:0071707
• induction of apoptosis by extracellular signals (IEA) | GO:0008624
• interleukin-19 production (IEA) | GO:0032622
• interleukin-2 production (IEA) | GO:0032623
• mitochondrial genome maintenance (IEA) | GO:0000002
• negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process (IEA) | GO:1902647
• negative regulation of complement-dependent cytotoxicity (IEA) | GO:1903660
• negative regulation of epithelial cell-cell adhesion involved in epithelium migration (IEA) | GO:1903682
• negative regulation of interleukin-1 production (IEA) | GO:0032692
• negative regulation of PERK-mediated unfolded protein response (IEA) | GO:1903898
• obsolete activation of pro-apoptotic gene products (IEA) | GO:0008633
• obsolete modification by symbiont of host morphology or physiology via protein secreted by type VII secretion system (IEA) | GO:0085023
• obsolete negative regulation of catalase activity (IEA) | GO:1902552
• obsolete negative regulation of histone H3-K18 acetylation (IEA) | GO:1902030
• obsolete primary charge separation in photosystem I (IEA) | GO:0009770
• obsolete regulation of histone H3-K27 methylation (IEA) | GO:0061085
• ommochrome biosynthetic process (IEA) | GO:0006727
• P granule assembly (IEA) | GO:1903863
• phagocytosis (IEA) | GO:0006909
• phagocytosis, engulfment (IEA) | GO:0006911
• plant-type cell wall modification (IEA) | GO:0009827
• polyamine acetylation (IEA) | GO:0032917
• positive regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process (IEA) | GO:1902643
• positive regulation of response to water deprivation (IEA) | GO:1902584
• pronuclear fusion (IEA) | GO:0007344
• propan-2-ol biosynthetic process (IEA) | GO:1902640
• protein localization to old growing cell tip (IEA) | GO:1903858
• prothoracic disc morphogenesis (IEA) | GO:0007470
• regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process (IEA) | GO:1902641
• regulation of complement-dependent cytotoxicity (IEA) | GO:1903659
• regulation of cytokinin dehydrogenase activity (IEA) | GO:1903856
• regulation of germ cell proliferation (IEA) | GO:1905936
• substrate-dependent cell migration, cell attachment to substrate (IEA) | GO:0006931
• tertiary alcohol biosynthetic process (IEA) | GO:1902645
• trachea gland development (IEA) | GO:0061153
• visceral muscle development (IEA) | GO:0007522

Domains

• ( PF00580 ) UvrD/REP helicase N-terminal domain
• ( PF13361 ) UvrD-like helicase C-terminal domain

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

No Data fetched for Homologs

General Information

No Data fetched for General Information

Associated Literature

1. Ref:23884606: Gao S, Xiong J, Zhang C, Berquist BR, Yang R, Zhao M, Molascon AJ, Kwiatkowski SY, Yuan D, Qin Z, Wen J, Kapler GM, Andrews PC, Miao W, Liu Y (2013) Impaired replication elongation in Tetrahymena mutants deficient in histone H3 Lys 27 monomethylation. Genes & development 27(15):1662-79

Sequences

>TTHERM_00864890(coding)
ATGCTGAATAACTAAAATGATTATAAAGTTATTAAATACAAAAATAAATTTGGTGAGGAT
TGCGAACTAAGGCCAAGTGAAGAGTAATTGAAAATTATTACATCAGAATTAAGGCAAGAT
CAAAAGATTATTGCGTGTGCTGGTTCTGGAAAAACTACTACTTTAGTTGCTAGACTTAAA
TATTTGATAGATCACGGTGTTTCACCTGAATCAATCATCATTAGTACTTTCAATGTAGAA
GCTGGAAGAAATATTCAAAGTAGAGCGATGGAATTGATTGGAGAATAATCTGCTAAAAAA
TTAGATATTGGAAATATTGATAAAATAGCTTTCCGTCTTTATTTTTAATATATAAAAAAT
AGCTAAAATGCTTAGTTTAAGCAGTTTGGGCTTAGTGTGAAAGAGTATTGTTATGAATTA
TTTAAGTTTTTATAAACAAGAGATGGAATAAAATATGTTTTAGACAGATATAAATATTTC
TTTTTTGATGAGTTTTAAGATGTTAATTAACTACAATATGATATATTGATGCTATTTAAA
AAGCATGGATGCTTCTTAGTTGTTATAGGGGATGATGCTTAAAATATATATGGATGGAGA
GATTCGAGAATAGATATTATATAAACAAGAATCGATGAGGATATTAAAAAGTTTTAGGGA
GCTCACATTAAAACATATATGCTTTCTACTAACTATAGATGCTCAAAACCTATCACTTTA
TTTTCTAATTCTATTATAGCTACTTCTAAAAATTTGATTTAAAAAAGTATGAGATATTTA
GTCAAAGAAGAAGGAGTGATTGAACTTAAACCATACTTGTAATGCTTTAAAGGATTATAT
AATTAGAATGAAGAAATAATCTCTCAGATAAAAAGTAAACTTAAAAGATATTAACTAAAA
GATATAGCTATATTATGCTCAACAAATTAGCCACTCAAGTTTTTTGAAGAGGCTCTTGAA
AAGCATAACGAAAAAAGCAGTTTAAAACTGAATTATATGAGTATGATAGGCAATAACTCC
AGTATTTATGGAGGTAAAACCAACTAAAGCGAACTATTAAAATAAGATAGAATTACTTTA
AGCACTATACATAGGGCAAAAGGTCTCGAATGGAAAGTGGTATTTTTCATTGGTGTAAAT
GATGAGTTTTTTCCTAATAACTTCCTAAGAGATCCTTCCAACTCTCTTACCAGATTAGAA
GAATGTAGAAGATTGTTTTATGTAGGAGCTACAAGAGCCATAAATGAACTTTATTTCGCT
ATGGTTAAAAATAATAAATGTCATAAAGTATGTAGATTTTTTAGTGGAATCAATGCAGAA
TTATATGAAAGAGATATAGATATTACAGATAATGATATGATAGTCGAAGAAGAAAATATA
AAAAAGGATTTTGAAAGAGATGTCTAAGTGACTAAAATCATAGAGCAGATGGACCACAAA
GATTTAAGTGAAGCTGATTAATTTTTATAAAATGTGGAGGAATTAGAAATTCGTTAAATA
CATCCAAAGAGCAATTTAAATGAATCTGAAATAAGAAATAATAACTTGTTTGTAGATTTA
GGTTTATATATCGACTTGCTAATATAAAGAACTCTTGCAGAATAGCTCAATGCTGAAAAC
GGTTACTCTTATGAATATGCTTAGATAGTTCTATTTTCTATTTTTTGGAGATCAGATAAG
GCAGAATTTATTTCAAAATATAGCACTTTTTTTAACAATAAAATGCTTGATTTCTCCGAT
ATTGAAGATGAAGAGGATTTCATAGAGGCATTCAATTTATTCTATAAATTTGGAAAAGTA
GATAGAATTTAGTAAAACATAAAACTCAATGGATTTGAAATTTAAACCCTTAGTACTATT
TACTAAATATTGAAAGAGTATACACAAAAATACAATATAGAATACAGTGTTATCACTCAC
TAAGTCGAGGAATTAAATGCCATAGCTAAAGAGTATTTTCCTGAAGATTATAATAAAGAA
CCTTATATGAATAGTTATAAAAAGTTTATGAATCCTTAATTAAAATGTAACAATATACTT
TTTGATATTTATTAAGTCAGTAAATGTGGTCAGTTATTTGATATGACTAGGAGAGTCCTT
TATAGGAATGATTTTTAAACTCTGAACCCTAAAAATATTTAAGATAACTTGAATAATTTT
GTAAAATACCTTTAATCTTTTAACTATGAGAAGATAAAAGTAAAATCAGTCATAACTCAT
GGCTTAAACTTAAAAGGAGAAATAGATTTACTAGCAGATGATACAATATATGAAATAAAG
GCTTCTTAGTTTTAATCTATCTCAAAGGAGTATATTCTCTAAGTTTTAGCCTATGCAGCT
TTGCTTAGGGTTGCACAAAATGTAGAAGTCAATCATATTGTATTTTATAACCCTTTAATT
GGAAAGATATATAAATATAGTATCTCTAATTGGCCTTATGCTTAGTAATACATTAAATTC
TTAACTGATAAATCACTGTAACTAGCTAATTCAAAGAAAAAAGTACTTGAACAAAGTGAG
GCTGAAGAAAAATAACAACTAGTTAACTTGAATCAAAATAAAGCAAATAATTCTCAGTAA
AATAATAACTAAGATAAGACCTAGGACACAAATAGTCAAACTACTAATTTTAATGAAATT
GGTGATTTAATTTAGTAAAAACTTCAGGAGGAAAAATTATAGTCGAAGCCATTATTTAAT
GTATCTGAATTCAGCTAACCATAAAACAGGCCAAGATCTCTATTTACAAAACAAACTGTT
TCAATAAAATCATCAACTGAATAAAAAAGCACAAGCACTGTATCTGGATATAGAAATTAG
GTTCCAGATTAGGGAGAAAACAAAAAGCCAAAAAATGTTTATAGAGACTTTAAGAAATTT
GTAAAGAATGAATAAATTGCATTATTAAAATAAAATATAAAATAAACTAAAATAATTGTA
GAAAGTGATCAAAGCTCTGAAAACGATGACATAGAAGAATATTCTTCTCTTAATATCAAA
AAAATTAGCAAAAATTAAATTTCTAGTTCTAATCTATAAAAAAATGTACTTCCGAAATCT
ACTCAGAATATTTTATCATAATTAGATGATATTGAAGAAGTTTCTTCCAAATTTATATAA
ATAGACTGA

>TTHERM_00864890(gene)
ATAAATTTTGCATGTATCTCATTTATTAAAAAATAAGGTTCAATTAATAATAACAAATAT
TTTACTACTATTACTTTATACTATTTGCTTTTACTAGAAAATAGAATTTAGGCTTAAAAC
AAATTTATTTTCTATTATATAATTCATATTTCTATTATTCTCTATTATTGAAACCTACTT
ACTGAAATGCTGAATAACTAAAATGATTATAAAGTTATTAAATACAAAAATAAATTTGGT
GAGGATTGCGAACTAAGGCCAAGTGAAGAGTAATTGAAAATTATTACATCAGAATTAAGG
CAAGATCAAAAGATTATTGCGTGTGCTGGTTCTGGAAAAACTACTACTTTAGTTGCTAGA
CTTAAATATTTGATAGATCACGGTGTTTCACCTGAATCAATCATCATTAGTACTTTCAAT
GTAGAAGCTGGAAGAAATATTCAAAGTAGAGCGATGGAATTGATTGGAGAATAATCTGCT
AAAAAATTAGATATTGGAAATATTGATAAAATAGCTTTCCGTCTTTATTTTTAATATATA
AAAAATAGCTAAAATGCTTAGTTTAAGCAGTTTGGGCTTAGTGTGAAAGAGTATTGTTAT
GAATTATTTAAGTTTTTATAAACAAGAGATGGAATAAAATATGTTTTAGACAGATATAAA
TATTTCTTTTTTGATGAGTTTTAAGATGTTAATTAACTACAATATGATATATTGATGCTA
TTTAAAAAGCATGGATGCTTCTTAGTTGTTATAGGGGATGATGCTTAAAATATATATGGA
TGGAGAGATTCGAGAATAGATATTATATAAACAAGAATCGATGAGGATATTAAAAAGTTT
TAGGGAGCTCACATTAAAACATATATGCTTTCTACTAACTATAGATGCTCAAAACCTATC
ACTTTATTTTCTAATTCTATTATAGCTACTTCTAAAAATTTGATTTAAAAAAGTATGAGA
TATTTAGTCAAAGAAGAAGGAGTGATTGAACTTAAACCATACTTGTAATGCTTTAAAGGA
TTATATAATTAGAATGAAGAAATAATCTCTCAGATAAAAAGTAAACTTAAAAGATATTAA
CTAAAAGATATAGCTATATTATGCTCAACAAATTAGCCACTCAAGTTTTTTGAAGAGGCT
CTTGAAAAGCATAACGAAAAAAGCAGTTTAAAACTGAATTATATGAGTATGATAGGCAAT
AACTCCAGTATTTATGGAGGTAAAACCAACTAAAGCGAACTATTAAAATAAGATAGAATT
ACTTTAAGCACTATACATAGGGCAAAAGGTCTCGAATGGAAAGTGGTATTTTTCATTGGT
GTAAATGATGAGTTTTTTCCTAATAACTTCCTAAGAGATCCTTCCAACTCTCTTACCAGA
TTAGAAGAATGTAGAAGATTGTTTTATGTAGGAGCTACAAGAGCCATAAATGAACTTTAT
TTCGCTATGGTTAAAAATAATAAATGTCATAAAGTATGTAGATTTTTTAGTGGAATCAAT
GCAGAATTATATGAAAGAGATATAGATATTACAGATAATGATATGATAGTCGAAGAAGAA
AATATAAAAAAGGATTTTGAAAGAGATGTCTAAGTGACTAAAATCATAGAGCAGATGGAC
CACAAAGATTTAAGTGAAGCTGATTAATTTTTATAAAATGTGGAGGAATTAGAAATTCGT
TAAATACATCCAAAGAGCAATTTAAATGAATCTGAAATAAGAAATAATAACTTGTTTGTA
GATTTAGGTTTATATATCGACTTGCTAATATAAAGAACTCTTGCAGAATAGCTCAATGCT
GAAAACGGTTACTCTTATGAATATGCTTAGATAGTTCTATTTTCTATTTTTTGGAGATCA
GATAAGGCAGAATTTATTTCAAAATATAGCACTTTTTTTAACAATAAAATGCTTGATTTC
TCCGATATTGAAGATGAAGAGGATTTCATAGAGGCATTCAATTTATTCTATAAATTTGGA
AAAGTAGATAGAATTTAGTAAAACATAAAACTCAATGGATTTGAAATTTAAACCCTTAGT
ACTATTTACTAAATATTGAAAGAGTATACACAAAAATACAATATAGAATACAGTGTTATC
ACTCACTAAGTCGAGGAATTAAATGCCATAGCTAAAGAGTATTTTCCTGAAGATTATAAT
AAAGAACCTTATATGAATAGTTATAAAAAGTTTATGAATCCTTAATTAAAATGTAACAAT
ATACTTTTTGATATTTATTAAGTCAGTAAATGTGGTCAGTTATTTGATATGACTAGGAGA
GTCCTTTATAGGAATGATTTTTAAACTCTGAACCCTAAAAATATTTAAGATAACTTGAAT
AATTTTGTAAAATACCTTTAATCTTTTAACTATGAGAAGATAAAAGTAAAATCAGTCATA
ACTCATGGCTTAAACTTAAAAGGAGAAATAGATTTACTAGCAGATGATACAATATATGAA
ATAAAGGCTTCTTAGTTTTAATCTATCTCAAAGGAGTATATTCTCTAAGTTTTAGCCTAT
GCAGCTTTGCTTAGGGTTGCACAAAATGTAGAAGTCAATCATATTGTATTTTATAACCCT
TTAATTGGAAAGATATATAAATATAGTATCTCTAATTGGCCTTATGCTTAGTAATACATT
AAATTCTTAACTGATAAATCACTGTAACTAGCTAATTCAAAGAAAAAAGTACTTGAACAA
AGTGAGGCTGAAGAAAAATAACAACTAGTTAACTTGAATCAAAATAAAGCAAATAATTCT
CAGTAAAATAATAACTAAGATAAGACCTAGGACACAAATAGTCAAACTACTAATTTTAAT
GAAATTGGTGATTTAATTTAGTAAAAACTTCAGGAGGAAAAATTATAGTCGAAGCCATTA
TTTAATGTATCTGAATTCAGCTAACCATAAAACAGGCCAAGATCTCTATTTACAAAACAA
ACTGTTTCAATAAAATCATCAACTGAATAAAAAAGCACAAGCACTGTATCTGGATATAGA
AATTAGGTTCCAGATTAGGGAGAAAACAAAAAGCCAAAAAATGTTTATAGAGACTTTAAG
AAATTTGTAAAGAATGAATAAATTGCATTATTAAAATAAAATATAAAATAAACTAAAATA
ATTGTAGAAAGTGATCAAAGCTCTGAAAACGATGACATAGAAGAATATTCTTCTCTTAAT
ATCAAAAAAATTAGCAAAAATTAAATTTCTAGTTCTAATCTATAAAAAAATGTACTTCCG
AAATCTACTCAGAATATTTTATCATAATTAGATGATATTGAAGAAGTTTCTTCCAAATTT
ATATAAATAGACTGATTACTTACAAATTTTTTCTAACTAATAATCAAAGCATACTTTTGC
TGAGCTCTCTTTCAATTATTCGTAATAGAGAGTTTTTAATATAAATATTAATGTAAACTG
TATATATTATTTTGTCATATAAAATTAAATAGTTATTTAGGCTTATTTATTTATTTATAG
CAATCAGAATATACTAAATAATAAATAGATCATTATCATATTCCAAAATATTAAATAATT
TTAATATGAACTAAATTA

>TTHERM_00864890(protein)
MLNNQNDYKVIKYKNKFGEDCELRPSEEQLKIITSELRQDQKIIACAGSGKTTTLVARLK
YLIDHGVSPESIIISTFNVEAGRNIQSRAMELIGEQSAKKLDIGNIDKIAFRLYFQYIKN
SQNAQFKQFGLSVKEYCYELFKFLQTRDGIKYVLDRYKYFFFDEFQDVNQLQYDILMLFK
KHGCFLVVIGDDAQNIYGWRDSRIDIIQTRIDEDIKKFQGAHIKTYMLSTNYRCSKPITL
FSNSIIATSKNLIQKSMRYLVKEEGVIELKPYLQCFKGLYNQNEEIISQIKSKLKRYQLK
DIAILCSTNQPLKFFEEALEKHNEKSSLKLNYMSMIGNNSSIYGGKTNQSELLKQDRITL
STIHRAKGLEWKVVFFIGVNDEFFPNNFLRDPSNSLTRLEECRRLFYVGATRAINELYFA
MVKNNKCHKVCRFFSGINAELYERDIDITDNDMIVEEENIKKDFERDVQVTKIIEQMDHK
DLSEADQFLQNVEELEIRQIHPKSNLNESEIRNNNLFVDLGLYIDLLIQRTLAEQLNAEN
GYSYEYAQIVLFSIFWRSDKAEFISKYSTFFNNKMLDFSDIEDEEDFIEAFNLFYKFGKV
DRIQQNIKLNGFEIQTLSTIYQILKEYTQKYNIEYSVITHQVEELNAIAKEYFPEDYNKE
PYMNSYKKFMNPQLKCNNILFDIYQVSKCGQLFDMTRRVLYRNDFQTLNPKNIQDNLNNF
VKYLQSFNYEKIKVKSVITHGLNLKGEIDLLADDTIYEIKASQFQSISKEYILQVLAYAA
LLRVAQNVEVNHIVFYNPLIGKIYKYSISNWPYAQQYIKFLTDKSLQLANSKKKVLEQSE
AEEKQQLVNLNQNKANNSQQNNNQDKTQDTNSQTTNFNEIGDLIQQKLQEEKLQSKPLFN
VSEFSQPQNRPRSLFTKQTVSIKSSTEQKSTSTVSGYRNQVPDQGENKKPKNVYRDFKKF
VKNEQIALLKQNIKQTKIIVESDQSSENDDIEEYSSLNIKKISKNQISSSNLQKNVLPKS
TQNILSQLDDIEEVSSKFIQID