Identifiers and Description

Gene Model Identifier

TTHERM_00913400

Standard Name

TTLL12A (Tubulin Tyrosine Ligase-Like )

Aliases

PreTt23744 | 162.m00073

Description

TTLL12A tubulin-tyrosine ligase family protein; Related to tubulin tyrosine ligase

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Molecular Function

• tubulin-tyrosine ligase activity (IEA) | GO:0004835

Biological Process

• cellular protein modification process (IEA) | GO:0006464
• peptidyl-amino acid modification (ISS) | GO:0018193

Domains

• ( PF00560 ) Leucine Rich Repeat
• ( PF03133 ) Tubulin-tyrosine ligase family
• ( PF07723 ) Leucine Rich Repeat

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_10477.1	9.997093137033517e-262
	Description: tubulin-tyrosine ligase (819 aa)
WormBase	WBGene00019837	9.997093137033517e-262
	Description: status:Partially_confirmed UniProt:Q21652 protein_id:CCD68402.1
Oxytricha	Contig22637.0.g50	1.0004236668521093e-146
	Description: Tubulin-tyrosine ligase family
WormBase	WBGene00008405	1.0000310450948521e-65
	Description: locus:ttll-12 Tubulin--tyrosine ligase-like protein 12 status:Confirmed UniProt:Q09512 protein_id:CAA87778.1
WormBase	WBGene00020822	1.0000310450948521e-65
	Description: status:Confirmed UniProt:Q22794 protein_id:CCD63212.1
Stentor Coeruleus	SteCoe_23134	1.733141042341547e-58
	Description: None
DictyBase	DDB_G0281541	0.0000000010002658722841845
	Description: DDB_G0281541 on chromosome: 3 position 4627625 to 4629265

General Information

No Data fetched for General Information

Associated Literature

1. Ref:15890843: Janke C, Rogowski K, Wloga D, Regnard C, Kajava AV, Strub JM, Temurak N, van Dijk J, Boucher D, van Dorsselaer A, Suryavanshi S, Gaertig J, Eddé B (2005) Tubulin polyglutamylase enzymes are members of the TTL domain protein family. Science (New York, N.Y.) 308(5729):1758-62

Sequences

>TTHERM_00913400(coding)
ATGGAATAACAAAAAGGTGAAATAGTATTAGAAGGAAAGTACAAGGATTTTTATGAGTTC
CACGGAGTCTAATTGTACGGAGCTGGTTTCCCTGCTCACTTAGTACCTTAATTATTAGAT
AAGTTAGAAAAAGAAGTTTTTGATTTCACTGATAGTTTTGCAGTTTAGGACAACTAGGAG
GAAGAAACTTTCTAATCAGTAGCTCTAGAAAATGTTGAAAAGCACTCCAAAGTTATTTTG
ATTGACCATTAATTCACATTCAAAATGGAGGGTTTGAGAAGCGCTCTTGAATCCAGTCCT
GAGCTAATCAACAAGCTAAGATACGAATTGCAATATTTTGGAGATAAAAAAAACATACCT
GGAATTACAAAATCAGATAAATTTGAATGCAAGGAAGTTGTTGAATTCGATGAACAAGGA
ATCGTTGATCCTACTACATTAGATATTTAAAAGGATGTTGTTTCTCTTTCCTTATTTGAT
AACTAAGTTGAGTCCTTAGATTTAGTCAGATAAGTCCTTTAGAAGTTACCAGCTTTGAAA
GTGCTCTTTTTGAACTACAACCCAGTCAGCGACACAGAAGGATTTTTCGAAAAAATCGAA
GAGGAGTTTCCCAATATTGAATTGTTAAATTCCAAGTTTACCAAAAATGCAACCGACTTT
GGTCTTAAGTTTGCTCACTTTAAGTACAACTTAGATAAGAGCACAAAGCTTAAAACTGAC
ATGATTAAATAGTTAGATTTATAGAAAAAGGGAGTCTTCAGATTAGAAGATTTTACAGTT
TTTACAGCTTTTAAGAATTTGATTCACTTAGATCTCTCTAAGAATGATTTCAAGGCTGAA
ACTGATACACCAAAGCTTTTAAATTTGTTATCTAAGTGCAGCAAGTTAAAAAATATAAAT
CTAGACTGGGAAGTAGAAATGCTTTTGTGGGATCTTTATGAATAAGGAAAGATTAAAGAA
GTTTGTCCTACTTTAATGAGTGTTAACGATAGAACCTTCGCTTATGGAAAACCTTAACCA
AACGAAGAAGATATACGCTTTATCATTAAGAATATCTGGAAGATTGCTGGCAATTACCGT
CTTATGAGTGAAGAATAGATGGATGAAACTTCTTACTGGTATTTAAATGATTTATGTGGT
ATCTCTGTATAGCACTCTGATACACCTAACATTCGTATGGTTCCTTTCCTTTATGCTCCT
AATAATTAATTAAAGGAAGCAAAGTCCTACACTATAATGTGGCCATTAGAGGATATCTCT
GCAGGAAGCTGCTTATTCAGAGATTATTTAGTTGGATTCGATGAAAAGTCACATCGTTCT
GCTAGACTTTCTATATGGTTCAACGTACCTGATGATTTCTTTATCAAGGCTAACCAAGAA
TACAAAAATAAATTGATGTAAACAACTTTGTATGGCAAAAAGTATATTTCTGAATTCAAG
AGTATCCCTGCTAAATTCGTAGGATTGAATGATACTTTGCCAAAATAGACACCTTTGAAG
GTTATCACTGACAACTCTCTTGTTTCTGAGTATCTCACTGCTCCTGAATTTTAACTTTGC
AAAACTCTTGAAGAAGCTAATGTTATTTTCTTGACTCACTGTTTTGAAGAAACTATTAGA
GACCACTACATGACTAAATTCTGCAACTAATTCCCAGATGAGTGCCATATTGTTCAAAAA
AATCATTTGGCTGATACAGTTTTCTCTACTCTTGGCCAAGTTGATTGGATTTAACCCACA
TATAACTTAAAAACTTAAATGAACGAATTTGTTGGTGAATATAAAAGAAGACGCAACACT
TTAGAAGATAATGTTTGGATCATCAAGGCTTTTAATTTAGCTAGAAGCTTAGATATGATA
GTAACCGATAATCTTGACTAAATCATTCGTTAAACAGAAACATTACCCAGATTAGCCTAA
AAATATATAACTAATCCAGTAACACTTTTTGGTAAGAAGATTGACTTGCGTTACATTGTT
TCAGTCAGATCACTTGAGCCTTTCGAAGTCTTCATCTATAAAGTCTTTTGGATTCGTACC
TCAAACAACGATTTCACAAATGATTATCGTTCTCGCGAAATCTATGAAACCCATTTTACA
GTTATGAATTATGGTAAAAAACTTAAATAAATTCACTATGATGAATTCATTGAAGAATTC
GAGAAAGAGTACACACAAATTAAATGGGCTGCAATTCATGATAAAATCAAAACTATGGTT
AAAGAATTGTTTATGGCTGTCTACAAGAAGTATCCTGGTATGCCTCATCCTAACTGTAGA
GGTTCTTATGGTATGGATGTTATGATTGAAAACGGAACTTTCTAGCCTAAATTGTTAGAA
CTTACATTCTCTCCAGACTGTGAACGTGCTTGCAAATACCATCCCCACTTCTTCAATGAC
ATGTTCAAGCTCTTCTTCTTGAACGACTAAGAACACCCCAACTATGAAAAGTTATGA

>TTHERM_00913400(gene)
ATGGAATAACAAAAAGGTGAAATAGTATTAGAAGGAAAGTACAAGGATTTTTATGAGTTC
CACGGAGTCTAATTGTACGGAGCTGGTTTCCCTGCTCACTTAGTACCTTAATTATTAGAT
AAGTTAGAAAAAGAAGTTTTTGATTTCACTGATAGTTTTGCAGTTTAGGACAACTAGGAG
GAAGAAACTTTCTAATCAGTAGCTCTAGAAAATGTTGAAAAGCACTCCAAAGTTATTTTG
ATTGACCATTAATTCACATTCAAAATGGAGGGTTTGAGAAGCGCTCTTGAATCCAGTCCT
GAGCTAATCAACAAGCTAAGATACGAATTGCAATATTTTGGAGATAAAAAAAACATACCT
GGAATTACAAAATCAGATAAATTTGAATGCAAGGAAGTTGTTGAATTCGATGAACAAGGA
ATCGTTGATCCTACTACATTAGATATTTAAAAGGATGTTGTTTCTCTTTCCTTATTTGAT
AACTAAGTTGAGTCCTTAGATTTAGTCAGATAAGTCCTTTAGAAGTTACCAGCTTTGAAA
GTGCTCTTTTTGAACTACAACCCAGTCAGCGACACAGAAGGATTTTTCGAAAAAATCGAA
GAGGAGTTTCCCAATATTGAATTGTTAAATTCCAAGTTTACCAAAAATGCAACCGACTTT
GGTCTTAAGTTTGCTCACTTTAAGTACAACTTAGATAAGAGCACAAAGCTTAAAACTGAC
ATGATTAAATAGTTAGATTTATAGAAAAAGGGAGTCTTCAGATTAGAAGATTTTACAGTT
TTTACAGCTTTTAAGAATTTGATTCACTTAGATCTCTCTAAGAATGATTTCAAGGCTGAA
ACTGATACACCAAAGCTTTTAAATTTGTTATCTAAGTGCAGCAAGTTAAAAAATATAAAT
CTAGACTGGGAAGTAGAAATGCTTTTGTGGGATCTTTATGAATAAGGAAAGATTAAAGAA
GTTTGTCCTACTTTAATGAGTGTTAACGATAGAACCTTCGCTTATGGAAAACCTTAACCA
AACGAAGAAGATATACGCTTTATCATTAAGAATATCTGGAAGATTGCTGGCAATTACCGT
CTTATGAGTGAAGAGTAAATATTACAAATAAATTATATATTTTTTTTGAATAAAACTCAG
CTTAATAATATAAATCTTTTTAGACTTAACAAAAGCAATTAATAAAATAGAAATAATTTT
TTTATTTAAAAATTAAATAAAATTAGATTAGAATTGATTGATTGATTCTAATCAAATTTA
ATAAATTATTTTTAATTCAATATTGATTTTTATTTAAAAAAAATAGATAGATGGATGAAA
CTTCTTACTGGTATTTAAATGATTTATGTGGTATCTCTGTATAGCACTCTGATACACCTA
ACATTCGTATGGTTCCTTTCCTTTATGCTCCTAATAATTAATTAAAGGAAGCAAAGTCCT
ACACTATAATGTGGCCATTAGAGGATATCTCTGCAGGAAGCTGCTTATTCAGAGATTATT
TAGTTGGATTCGATGAAAAGTCACATCGTTCTGCTAGACTTTCTATATGGTTCAACGTAC
CTGATGATTTCTTTATCAAGGCTAACCAAGAATACAAAAATAAATTGATGTAAACAACTT
TGTATGGCAAAAAGTATATTTCTGAATTCAAGAGTATCCCTGCTAAATTCGTAGGATTGA
ATGATACTTTGCCAAAATAGACACCTTTGAAGGTTATCACTGACAACTCTCTTGTTTCTG
AGTATCTCACTGCTCCTGAATTTTAACTTTGCAAAACTCTTGAAGAAGCTAATGTTATTT
TCTTGACTCACTGTTTTGAAGAAACTATTAGAGACCACTACATGACTAAATTCTGCAACT
AATTCCCAGATGAGTGCCATATTGTTCAAAAAAATCATTTGGCTGATACAGTTTTCTCTA
CTCTTGGCCAAGTTGATTGGATTTAACCCACATATAACTTAAAAACTTAAATGAACGAAT
TTGTTGGTGAATATAAAAGAAGACGCAACACTTTAGAAGATAATGTTTGGATCATCAAGG
CTTTTAATTTAGCTAGAAGCTTAGATATGATAGTAACCGATAATCTTGACTAAATCATTC
GTTAAACAGAAACATTACCCAGATTAGCCTAAAAATATATAACTAATCCAGTAACACTTT
TTGGTAAGAAGATTGACTTGCGTTACATTGTTTCAGTCAGATCACTTGAGCCTTTCGAAG
TCTTCATCTATAAAGTCTTTTGGATTCGTACCTCAAACAACGATTTCACAAATGATTATC
GTTCTCGCGAAATCTATGAAACCCATTTTACAGTTATGAATTATGGTAAAAAACTTAAAT
AAATTCACTATGATGAATTCATTGAAGAATTCGAGAAAGAGTACACACAAATTAAATGGG
CTGCAATTCATGATAAAATCAAAACTATGGTTAAAGAATTGTTTATGGCTGTCTACAAGA
AGTATCCTGGTATGCCTCATCCTAACTGTAGAGGTTCTTATGGTATGGATGTTATGATTG
AAAACGGAACTTTCTAGCCTAAATTGTTAGAACTTACATTCTCTCCAGACTGTGAACGTG
CTTGCAAATACCATCCCCACTTCTTCAATGACATGTTCAAGCTCTTCTTCTTGAACGACT
AAGAACACCCCAACTATGAAAAGTTATGA

>TTHERM_00913400(protein)
MEQQKGEIVLEGKYKDFYEFHGVQLYGAGFPAHLVPQLLDKLEKEVFDFTDSFAVQDNQE
EETFQSVALENVEKHSKVILIDHQFTFKMEGLRSALESSPELINKLRYELQYFGDKKNIP
GITKSDKFECKEVVEFDEQGIVDPTTLDIQKDVVSLSLFDNQVESLDLVRQVLQKLPALK
VLFLNYNPVSDTEGFFEKIEEEFPNIELLNSKFTKNATDFGLKFAHFKYNLDKSTKLKTD
MIKQLDLQKKGVFRLEDFTVFTAFKNLIHLDLSKNDFKAETDTPKLLNLLSKCSKLKNIN
LDWEVEMLLWDLYEQGKIKEVCPTLMSVNDRTFAYGKPQPNEEDIRFIIKNIWKIAGNYR
LMSEEQMDETSYWYLNDLCGISVQHSDTPNIRMVPFLYAPNNQLKEAKSYTIMWPLEDIS
AGSCLFRDYLVGFDEKSHRSARLSIWFNVPDDFFIKANQEYKNKLMQTTLYGKKYISEFK
SIPAKFVGLNDTLPKQTPLKVITDNSLVSEYLTAPEFQLCKTLEEANVIFLTHCFEETIR
DHYMTKFCNQFPDECHIVQKNHLADTVFSTLGQVDWIQPTYNLKTQMNEFVGEYKRRRNT
LEDNVWIIKAFNLARSLDMIVTDNLDQIIRQTETLPRLAQKYITNPVTLFGKKIDLRYIV
SVRSLEPFEVFIYKVFWIRTSNNDFTNDYRSREIYETHFTVMNYGKKLKQIHYDEFIEEF
EKEYTQIKWAAIHDKIKTMVKELFMAVYKKYPGMPHPNCRGSYGMDVMIENGTFQPKLLE
LTFSPDCERACKYHPHFFNDMFKLFFLNDQEHPNYEKL