Identifiers and Description

Gene Model Identifier

TTHERM_00923170

Standard Name

TPA9 (Tetrahymena P-type ATPase )

Aliases

PreTt21196 | 164.m00089

Description

TPA9 cation-transporting ATPase putative; Novel P-type ATPase with undefined ion specificity; shares certain homology to Plasmodium ATPase-1; constitutively expressed; starvation upregulates expression; P-type ATPase, subfamily V

Genome Browser (Macronucleus)

Full Screen View


Genome Browser (Micronucleus)

Full Screen View

External Links

Gene Ontology Annotations

Cellular Component

Molecular Function

Biological Process

  • cell adhesion involved in multi-species biofilm formation (IEA) | GO:0043710
  • cellular response to magnesium ion (IEA) | GO:0071286
  • cytoplasmic actin-based contraction involved in forward cell motility (IEA) | GO:0060328
  • ferrichrome biosynthetic process, peptide formation (IEA) | GO:0031199
  • gastrulation involving germ band extension (IEA) | GO:0010004
  • glutamate metabolic process (IEA) | GO:0006536
  • heme A biosynthetic process (IEA) | GO:0006784
  • heme biosynthetic process (IEA) | GO:0006783
  • heterophilic cell adhesion involved in cytoadherence to microvasculature, mediated by parasite protein (IEA) | GO:0043706
  • homogentisate metabolic process (IEA) | GO:1901999
  • interleukin-19 production (IEA) | GO:0032622
  • interleukin-2 production (IEA) | GO:0032623
  • loss of chromatin silencing (IEA) | GO:0006345
  • mitotic nuclear division (IEA) | GO:0007067
  • monoatomic ion transport (ISS) | GO:0006811
  • negative regulation of interleukin-1 production (IEA) | GO:0032692
  • negative regulation of PERK-mediated unfolded protein response (IEA) | GO:1903898
  • obsolete modulation by symbiont of defense-related host calcium-dependent protein kinase pathway (IEA) | GO:0052168
  • obsolete movement in symbiont environment (IEA) | GO:0052193
  • obsolete negative regulation of histone H3-K18 acetylation (IEA) | GO:1902030
  • obsolete negative regulation of transcription during mitotic cell cycle (IEA) | GO:0007068
  • obsolete regulation of transcription from RNA polymerase II promoter involved in response to osmotic stress (IEA) | GO:1902032
  • ommochrome biosynthetic process (IEA) | GO:0006727
  • phagocytosis (IEA) | GO:0006909
  • phenanthrene catabolic process via trans-9(R),10(R)-dihydrodiolphenanthrene (IEA) | GO:0018956
  • plant-type cell wall modification (IEA) | GO:0009827
  • polyamine acetylation (IEA) | GO:0032917
  • positive regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process (IEA) | GO:1902643
  • positive regulation of ATF6-mediated unfolded protein response (IEA) | GO:1903893
  • process resulting in tolerance to ketone (IEA) | GO:1990369
  • propan-2-ol biosynthetic process (IEA) | GO:1902640
  • proteasome storage granule disassembly (IEA) | GO:1902907
  • protein localization to old growing cell tip (IEA) | GO:1903858
  • regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process (IEA) | GO:1902641
  • regulation of dendrite extension (IEA) | GO:1903859
  • regulation of hematopoietic stem cell proliferation (IEA) | GO:1902033
  • regulation of interferon-beta secretion (IEA) | GO:0035547
  • regulation of response to type II interferon (IEA) | GO:0060330
  • response to osmotic stress (IEA) | GO:0006970
  • rRNA pseudouridine synthesis (IEA) | GO:0031118
  • symbiont-mediated suppression of host innate immune response (IEA) | GO:0052170
  • tertiary alcohol biosynthetic process (IEA) | GO:1902645

Domains

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

No Data fetched for Homologs

General Information

No Data fetched for General Information

Associated Literature

  1. Ref:11952090: Linder JU, Schultz JE (2002) Guanylyl cyclases in unicellular organisms. Molecular and cellular biochemistry 230(1-2):149-58
  2. Ref:10428960: Linder JU, Engel P, Reimer A, Krüger T, Plattner H, Schultz A, Schultz JE (1999) Guanylyl cyclases with the topology of mammalian adenylyl cyclases and an N-terminal P-type ATPase-like domain in Paramecium, Tetrahymena and Plasmodium. The EMBO journal 18(15):4222-32
  3. Ref:9124316: Wang S, Takeyasu K (1997) Primary structure and evolution of the ATP-binding domains of the P-type ATPases in Tetrahymena thermophila. The American journal of physiology 272(2 Pt 1):C715-28
  4. Ref:9405804: Wang S, Gao D, Penny J, Krishna S, Takeyasu K (1997) P-type ATPases in Tetrahymena. Annals of the New York Academy of Sciences 834( ):158-60

Sequences 

>TTHERM_00923170(coding)
ATGAGAGTTAGCTCAATTGAGGCTGAAATGGAAAACCCTATTGACGTAGATAAAACAGAC
GTAGAGGGTGAATTAAAAATTAAATAAGTCACTCTGCTCAGAGAAAATATAGTTAAAAAA
ATCGTCTTTTTCCTTGTTGCTATTTTTTGCTCCGACAGACCTAGCGTTCTAAAGAAAGTA
TTTTATGAAGAAGTATCTAAATAAGAAGAAGCCACCCATGTTTATGTTCTTGCTTCAGAT
TTGACAGATTACATAGAAGAAGCTAGCTTGAAAGAAAACCCCGAAGAAGGAGGAGAAAAG
TCTATTTATTTTGTAAACAGGCTCTAAAAGTACATCTACCACAAAAAGCAAAATAAATTT
AGAGCTATTGAATACTTTATCTAAGGCAAGTCATACTCTGAAATTGCTAATAATAAACCA
CTCGCTACAGGCAGAGTTGATCAATTACTCGCTTACTATGGAAAGAGTGAAATAGAAATC
AATGTACCATCTTTCTTAACTTTAATGTGGAGAGAGTTCAAAAAACCTATTAACTTTTTA
CTTTATTTTGGTATCATAGTTTGGGGTATTGAACAAATGTATGTTTCTACTGCTATTACT
GTTGTTTTTACCACAACTATTAATTCTCTTATTTGCATTTATATTCGCGGTGTCATGTAA
AAGCTAAAGGATGCCTGTCTTAATAACACTTCTGTCATAGTATAAAGACATAATGGCTAA
GGATACTAAGAAATAACAGTAGCATCTAATATGATAGCTCCTGGTGATATAGTTCTCTTC
AAAAGAGAAGTTACTCTCCCTTTTGACTGTGTAATTTTGGAAGGCTCTTGCTAAGTTACT
GAAGCCAATATTACAGGTGAAAACGTTGCAATCGGAAAGTGTCAAATACCTACTGATCAT
CACAATGATATTTTTAAATATGAATCAAGCAAATCTCACACTCTCTTCTAAGGTACTCAA
TTGATGAAGATTGAAGATGATATCTTAAAAGTAATTGTTGTAAGAACTGGTTTTGGAAGC
TACAAGGGTCAAATTATTAGAGCTTTACTTTATCCCAAGCCTTTCAATAAAAAATTCTAA
CAATAAGCTGTCAAGTTAACTATTTTAATGGCTACCCTTTTGCTTATCGGTTTCCTTTCT
ACCCTTTCTAGACTCCTTGATATTGAACTTCCTCCTTTGTTCATAGCTTTTAGATTCTTA
GATATTCTCATCTATAGTGCTCCTCCTGGTATGCCTATGCTTATCGCCATTACAAACTTC
GTTGGCTTGAAAAGATTAAAAAATAATTAGATTTTAGGATAAGATCCTAACTCTGCAAGT
TAAGCTGGTAGAATTTAAACTCTTTGCTTTGATAAGACTGGTACTCTTACTGAAGATAAG
GTTGATTTAATTGGTTACCAATTGAAAGGATAGAATCAAACATTCGATAAGATTCAATGC
TAAGATCCTAACAATATCTCAATTGAACACAAACTCTTTAGTATTTGCCATGAAGTAACA
AAAATTAACAATAAGCTTTTAGGTGATTTAATGGATGTAAAAATGGCTGAATTCAGTACT
CTCGATATAGATTACGACCATGAAGCCAAATAACACTACTCTAAATCAGGTAATAAAAGA
TTCTATTGTATCTAAGTTAACTAATTCCATTCTGAATACCAATCTATGAGTGTTGTTTGC
AAGGAAGTTGATATGATCACCAAGGAATTCAAGCATTACTTCTTCATCAAGGGATCTCCT
GAAAAGATTCAATCCTTGTCACACGTTTAATCTTCAGAAAAAGCTCAATTAAGTACCTTG
ATTAATGAAGGATACAGAATTCTTGGATTTGGTTACAAGGAAATTCCTTAAAGTGAAATA
GATGCCTTTTTAGATTTAAGCAGAGAATAACAAGAAGCCAATGTTTAATCTCTTGGTTTC
CTTATTTATAAGAATAATCTTAAACCTGACACTCAAGAAGTGATCAAAGAATTCAAAGAA
GCATGTTACAATATTAAGGTTATCTCTGGTGATAATCCAATCACTACTTTAAAAATATCC
TAAGAATTAGAAATCGTCAATAGAAAAAATCCAACAGTTATCATCAACTTTGAGGAAACT
GAAAATGTCAAGAGTCATCTTATTATCACTGAAATCTAACCTGATAACTCAACTCAAGTA
ATTGATTTCAGTTCAGCTCAAAATGAATAAGACTACATTAATAAATAAATGAGTTATTGC
TGTGATGCTTTCCTTAATAACAAATCTTTTTGTTTCAGCGGTAAAGCCCATTACTACTTC
TAGCTTAAGGCCAAGACTGACCATATTTCATTCAAGCCTGAATGGGTTAAAATGCAAGAT
AAATCTGTCTAAAAAATAATTTCTTTCTATCAAATGTTGATAATTAACACCAATGTTTTC
GCTAGAACTCAACCTGAATAAAAGCAAACTATTGTTAGACTCTTGAAAGAAAGTGACTAA
ATAGTATGTATGGTTGGTGATGGTGCAAATGACTGCTCCGCTATTCGTGAAGCAGATGTC
GGTATTTCTTTTGCTGAAGCTGATGGTTAATTCTCTTCATCCTATGTATCTTTATCAACT
TCTCTTTCCTGCGTTAAAAGAGTTTTGTTAGAAGGTAGAGTTAATTTATCTAATAGTGTA
GAAATTTTCAAGGGTTACTTACAAGTTGCACTTTTGAGATATTTAGGTTTCTTGACTTTA
GCTTACTTCTACTCATCCTACAGTAGTGGTTAAATGGATTGGTAAGCTTTAGCCTCAGGT
TACTTCTTAGTTTATTTGATATTAGGTTGCAACACACCCTTAAAGAAGCTCGAAAAGAGT
GTTTTCGATGATAACCTTTTCAGCATATATAATGTTACTTCTGTACTTTTTGGATTCACT
TTGCATATTTTGTCTATTGTTGGGTGCGTTGAAAGTCTTCATGCTAGTCCCATTTACAAG
GAAGTAAACAGCTTAGACGCTGAAAATAACTTCTAATTTGAGACTCAACACAATACTGTT
TTGAATTTCAATATTTTGATCAATTTCTTCTATGTGATTATTTCTAACCACATCGGAAAA
CCTATGAAAGATAGATATTATAAGAACACTATTGCCTATCTTATGATTTGGGGTTAATTT
ATACATGCAAATGTTATGATTTTTACAAGTTCTGCTTATCCTGGAGCATACACATCATGG
GTTGATCTTCCTGATACTACTCTTAGATTAAGAATTTTCTTCATCTCTAACGGTTTAGGT
CTACTTCTCCTTGCCTATGAACTTATTTTTGCCAGAAGAATTTTCGTTAAACTTTACACA
AGAAGTCAAGAAAGAAAAAGAGCTGCTCATATGTAATAGCTCATCGACCATATTAGAAGT
TGA



>TTHERM_00923170(gene)
ATTTTTAAATATTAAAAAATAAAAACAACAAACTTACTTAAATGAGAGTTAGCTCAATTG
AGGCTGAAATGGAAAACCCTATTGACGTAGATAAAACAGACGTAGAGGGTGAATTAAAAA
TTAAATAAGTCACTCTGCTCAGAGAAAATATAGTTAAAAAAATCGTCTTTTTCCTTGTTG
CTATTTTTTGCTCCGACAGACCTAGCGTTCTAAAGAAAGTATTTTATGAAGAAGTATCTA
AATAAGAAGAAGCCACCCATGTTTATGTTCTTGCTTCAGATTTGACAGATTACATAGAAG
AAGCTAGCTTGAAAGAAAACCCCGAAGAAGGAGGAGAAAAGTCTATTTATTTTGTAAACA
GGCTCTAAAAGTACATCTACCACAAAAAGCAAAATAAATTTAGAGCTATTGAATACTTTA
TCTAAGGCAAGTCATACTCTGAAATTGCTAATAATAAACCACTCGCTACAGGCAGAGTTG
ATCAATTACTCGCTTACTATGGAAAGAGTGAAATAGAAATCAATGTACCATCTTTCTTAA
CTTTAATGTGGAGAGAGTTCAAAAAACCTATTAACTTTTTACTTTATTTTGGTATCATAG
TTTGGGGTATTGAACAAATGTATGTTTCTACTGCTATTACTGTTGTTTTTACCACAACTA
TTAATTCTCTTATTTGCATTTATATTCGCGGTGTCATGTAAAAGCTAAAGGATGCCTGTC
TTAATAACACTTCTGTCATAGTATAAAGACATAATGGCTAAGGATACTAAGAAATAACAG
TAGCATCTAATATGATAGCTCCTGGTGATATAGTTCTCTTCAAAAGAGAAGTTACTCTCC
CTTTTGACTGTGTAATTTTGGAAGGCTCTTGCTAAGTTACTGAAGCCAATATTACAGGTG
AAAACGTTGCAATCGGAAAGTGTCAAATACCTACTGATCATCACAATGATATTTTTAAAT
ATGAATCAAGCAAATCTCACACTCTCTTCTAAGGTACTCAATTGATGAAGATTGAAGATG
ATATCTTAAAAGTAATTGTTGTAAGAACTGGTTTTGGAAGCTACAAGGGTCAAATTATTA
GAGCTTTACTTTATCCCAAGCCTTTCAATAAAAAATTCTAACAATAAGCTGTCAAGTTAA
CTATTTTAATGGCTACCCTTTTGCTTATCGGTTTCCTTTCTACCCTTTCTAGACTCCTTG
ATATTGAACTTCCTCCTTTGTTCATAGCTTTTAGATTCTTAGATATTCTCATCTATAGTG
CTCCTCCTGGTATGCCTATGCTTATCGCCATTACAAACTTCGTTGGCTTGAAAAGATTAA
AAAATAATTAGATTTTAGGATAAGATCCTAACTCTGCAAGTTAAGCTGGTAGAATTTAAA
CTCTTTGCTTTGATAAGACTGGTACTCTTACTGAAGATAAGGTTGATTTAATTGGTTACC
AATTGAAAGGATAGAATCAAACATTCGATAAGATTCAATGCTAAGATCCTAACAATATCT
CAATTGAACACAAACTCTTTAGTATTTGCCATGAAGTAACAAAAATTAACAATAAGCTTT
TAGGTGATTTAATGGATGTAAAAATGGCTGAATTCAGTACTCTCGATATAGATTACGACC
ATGAAGCCAAATAACACTACTCTAAATCAGGTAATAAAAGATTCTATTGTATCTAAGTTA
ACTAATTCCATTCTGAATACCAATCTATGAGTGTTGTTTGCAAGGAAGTTGATATGATCA
CCAAGGAATTCAAGCATTACTTCTTCATCAAGGGATCTCCTGAAAAGATTCAATCCTTGT
CACACGTTTAATCTTCAGAAAAAGCTCAATTAAGTACCTTGATTAATGAAGGATACAGAA
TTCTTGGATTTGGTTACAAGGAAATTCCTTAAAGTGAAATAGATGCCTTTTTAGATTTAA
GCAGAGAATAACAAGAAGCCAATGTTTAATCTCTTGGTTTCCTTATTTATAAGAATAATC
TTAAACCTGACACTCAAGAAGTGATCAAAGAATTCAAAGAAGCATGTTACAATATTAAGG
TTATCTCTGGTGATAATCCAATCACTACTTTAAAAATATCCTAAGAATTAGAAATCGTCA
ATAGAAAAAATCCAACAGTTATCATCAACTTTGAGGAAACTGAAAATGTCAAGAGTCATC
TTATTATCACTGAAATCTAACCTGATAACTCAACTCAAGTAATTGATTTCAGTTCAGCTC
AAAATGAATAAGACTACATTAATAAATAAATGAGTTATTGCTGTGATGCTTTCCTTAATA
ACAAATCTTTTTGTTTCAGCGGTAAAGCCCATTACTACTTCTAGCTTAAGGCCAAGACTG
ACCATATTTCATTCAAGCCTGAATGGGTTAAAATGCAAGATAAATCTGTCTAAAAAATAA
TTTCTTTCTATCAAATGTTGATAATTAACACCAATGTTTTCGCTAGAACTCAACCTGAAT
AAAAGCAAACTATTGTTAGACTCTTGAAAGAAAGTGACTAAATAGTATGTATGGTTGGTG
ATGGTGCAAATGACTGCTCCGCTATTCGTGAAGCAGATGTCGGTATTTCTTTTGCTGAAG
CTGATGGTTAATTCTCTTCATCCTATGTATCTTTATCAACTTCTCTTTCCTGCGTTAAAA
GAGTTTTGTTAGAAGGTAGAGTTAATTTATCTAATAGTGTAGAAATTTTCAAGGGTTACT
TACAAGTTGCACTTTTGAGATATTTAGGTTTCTTGACTTTAGCTTACTTCTACTCATCCT
ACAGTAGTGGTTAAATGGATTGGTAAGCTTTAGCCTCAGGTTACTTCTTAGTTTATTTGA
TATTAGGTTGCAACACACCCTTAAAGAAGCTCGAAAAGAGTGTTTTCGATGATAACCTTT
TCAGCATATATAATGTTACTTCTGTACTTTTTGGATTCACTTTGCATATTTTGTCTATTG
TTGGGTGCGTTGAAAGTCTTCATGCTAGTCCCATTTACAAGGAAGTAAACAGCTTAGACG
CTGAAAATAACTTCTAATTTGAGACTCAACACAATACTGTTTTGAATTTCAATATTTTGA
TCAATTTCTTCTATGTGATTATTTCTAACCACATCGGAAAACCTATGAAAGATAGATATT
ATAAGAACACTATTGCCTATCTTATGATTTGGGGTTAATTTATACATGCAAATGTTATGA
TTTTTACAAGTTCTGCTTATCCTGGAGCATACACATCATGGGTTGATCTTCCTGATACTA
CTCTTAGATTAAGAATTTTCTTCATCTCTAACGGTTTAGGTCTACTTCTCCTTGCCTATG
AACTTATTTTTGCCAGAAGAATTTTCGTTAAACTTTACACAAGAAGTCAAGAAAGAAAAA
GAGCTGCTCATATGTAATAGCTCATCGACCATATTAGAAGTTGATTATAATTTAAGATTA
AATTATTTTCAATAAAATTTTTGATTTTTAACTAAAAATGATAGTCAATTAACTACTTTA
TATTTTACCAAATATTAAAATATATTCATTCTCTAAATATAAATAAATTATAAACTTAGT
TACATTTTACATTTACTTTATATTTGTAACTTTTTACTAATTATTTTCATCAAAAAAAAA
A



>TTHERM_00923170(protein)
MRVSSIEAEMENPIDVDKTDVEGELKIKQVTLLRENIVKKIVFFLVAIFCSDRPSVLKKV
FYEEVSKQEEATHVYVLASDLTDYIEEASLKENPEEGGEKSIYFVNRLQKYIYHKKQNKF
RAIEYFIQGKSYSEIANNKPLATGRVDQLLAYYGKSEIEINVPSFLTLMWREFKKPINFL
LYFGIIVWGIEQMYVSTAITVVFTTTINSLICIYIRGVMQKLKDACLNNTSVIVQRHNGQ
GYQEITVASNMIAPGDIVLFKREVTLPFDCVILEGSCQVTEANITGENVAIGKCQIPTDH
HNDIFKYESSKSHTLFQGTQLMKIEDDILKVIVVRTGFGSYKGQIIRALLYPKPFNKKFQ
QQAVKLTILMATLLLIGFLSTLSRLLDIELPPLFIAFRFLDILIYSAPPGMPMLIAITNF
VGLKRLKNNQILGQDPNSASQAGRIQTLCFDKTGTLTEDKVDLIGYQLKGQNQTFDKIQC
QDPNNISIEHKLFSICHEVTKINNKLLGDLMDVKMAEFSTLDIDYDHEAKQHYSKSGNKR
FYCIQVNQFHSEYQSMSVVCKEVDMITKEFKHYFFIKGSPEKIQSLSHVQSSEKAQLSTL
INEGYRILGFGYKEIPQSEIDAFLDLSREQQEANVQSLGFLIYKNNLKPDTQEVIKEFKE
ACYNIKVISGDNPITTLKISQELEIVNRKNPTVIINFEETENVKSHLIITEIQPDNSTQV
IDFSSAQNEQDYINKQMSYCCDAFLNNKSFCFSGKAHYYFQLKAKTDHISFKPEWVKMQD
KSVQKIISFYQMLIINTNVFARTQPEQKQTIVRLLKESDQIVCMVGDGANDCSAIREADV
GISFAEADGQFSSSYVSLSTSLSCVKRVLLEGRVNLSNSVEIFKGYLQVALLRYLGFLTL
AYFYSSYSSGQMDWQALASGYFLVYLILGCNTPLKKLEKSVFDDNLFSIYNVTSVLFGFT
LHILSIVGCVESLHASPIYKEVNSLDAENNFQFETQHNTVLNFNILINFFYVIISNHIGK
PMKDRYYKNTIAYLMIWGQFIHANVMIFTSSAYPGAYTSWVDLPDTTLRLRIFFISNGLG
LLLLAYELIFARRIFVKLYTRSQERKRAAHMQQLIDHIRS