Identifiers and Description

Gene Model Identifier

TTHERM_00923170

Standard Name

TPA9 (Tetrahymena P-type ATPase )

Aliases

PreTt21196 | 164.m00089

Description

TPA9 cation-transporting ATPase putative; Novel P-type ATPase with undefined ion specificity; shares certain homology to Plasmodium ATPase-1; constitutively expressed; starvation upregulates expression

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

Gene Ontology Annotations

Molecular Function

• glutathionylspermidine synthase activity (ISS) | GO:0008885 | Ref:9124316
• mercury ion transmembrane transporter activity (ISS) | GO:0015097 | Ref:9124316
• polyketide synthase activity (IEA) | GO:0016218

Biological Process

• cocaine biosynthetic process (IDA) | GO:0050799 | Ref:9124316
• creatine biosynthetic process (IEA) | GO:0006601
• miRNA loading onto RISC (ISS) | GO:0035280 | Ref:9124316

Domains

• ( PF00122 ) E1-E2 ATPase
• ( PF00690 ) Cation transporter/ATPase, N-terminus
• ( PF00702 ) haloacid dehalogenase-like hydrolase
• ( PF02357 ) Transcription termination factor nusG
• ( TIGR00099 ) Cof-like hydrolase
• ( TIGR01116 ) calcium-translocating P-type ATPase, SERCA-type
• ( TIGR01494 ) ATPase, P-type (transporting), HAD superfamily,
• ( TIGR01512 ) cadmium-translocating P-type ATPase
• ( TIGR01517 ) calcium-translocating P-type ATPase, PMCA-type
• ( TIGR01522 ) calcium-transporting P-type ATPase, PMR1-type
• ( TIGR01524 ) magnesium-translocating P-type ATPase
• ( TIGR01525 ) heavy metal translocating P-type ATPase
• ( TIGR01647 ) plasma-membrane proton-efflux P-type ATPase
• ( TIGR01652 ) phospholipid-translocating P-type ATPase, flippase
• ( TIGR01657 ) P-type ATPase of unknown pump

Gene Expression Profile

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_13231.1	9.997093137033517e-262
	Description: E1-E2 ATPase (1120 aa)
Oxytricha	Contig797.1.g89	4.998549705704758e-84
	Description: E1-E2 ATPase
WormBase	WBGene00022010	7.001663834819337e-84
	Description: locus:catp-7 status:Partially_confirmed UniProt:Q86FP2 protein_id:CCD71143.1
DictyBase	DDB_G0284849	5.000996804856152e-78
	Description: DDB_G0284849 on chromosome: 4 position 2557758 to 2561551
SGD	YOR291W	8.002162267243937e-73
	Description: YPK9 Vacuolar protein with a possible role in sequestering heavy metals; has similarity to the type V P-type ATPase Spf1p; homolog of human ATP13A2 (PARK9), mutations in which are associated with Parkinson disease and Kufor-Rakeb syndrome
Stentor Coeruleus	SteCoe_30916	4.4737793061811207e-38
	Description: None

General Information

No Data fetched for General Information

Associated Literature

1. Ref:11952090: Linder JU, Schultz JE (2002) Guanylyl cyclases in unicellular organisms. Molecular and cellular biochemistry 230(1-2):149-58
2. Ref:10428960: Linder JU, Engel P, Reimer A, Krüger T, Plattner H, Schultz A, Schultz JE (1999) Guanylyl cyclases with the topology of mammalian adenylyl cyclases and an N-terminal P-type ATPase-like domain in Paramecium, Tetrahymena and Plasmodium. The EMBO journal 18(15):4222-32
3. Ref:9124316: Wang S, Takeyasu K (1997) Primary structure and evolution of the ATP-binding domains of the P-type ATPases in Tetrahymena thermophila. The American journal of physiology 272(2 Pt 1):C715-28
4. Ref:9405804: Wang S, Gao D, Penny J, Krishna S, Takeyasu K (1997) P-type ATPases in Tetrahymena. Annals of the New York Academy of Sciences 834( ):158-60

Sequences

>TTHERM_00923170(coding)
ATGAGAGTTAGCTCAATTGAGGCTGAAATGGAAAACCCTATTGACGTAGATAAAACAGAC
GTAGAGGGTGAATTAAAAATTAAATAAGTCACTCTGCTCAGAGAAAATATAGTTAAAAAA
ATCGTCTTTTTCCTTGTTGCTATTTTTTGCTCCGACAGACCTAGCGTTCTAAAGAAAGTA
TTTTATGAAGAAGTATCTAAATAAGAAGAAGCCACCCATGTTTATGTTCTTGCTTCAGAT
TTGACAGATTACATAGAAGAAGCTAGCTTGAAAGAAAACCCCGAAGAAGGAGGAGAAAAG
TCTATTTATTTTGTAAACAGGCTCTAAAAGTACATCTACCACAAAAAGCAAAATAAATTT
AGAGCTATTGAATACTTTATCTAAGGCAAGTCATACTCTGAAATTGCTAATAATAAACCA
CTCGCTACAGGCAGAGTTGATCAATTACTCGCTTACTATGGAAAGAGTGAAATAGAAATC
AATGTACCATCTTTCTTAACTTTAATGTGGAGAGAGTTCAAAAAACCTATTAACTTTTTA
CTTTATTTTGGTATCATAGTTTGGGGTATTGAACAAATGTATGTTTCTACTGCTATTACT
GTTGTTTTTACCACAACTATTAATTCTCTTATTTGCATTTATATTCGCGGTGTCATGTAA
AAGCTAAAGGATGCCTGTCTTAATAACACTTCTGTCATAGTATAAAGACATAATGGCTAA
GGATACTAAGAAATAACAGTAGCATCTAATATGATAGCTCCTGGTGATATAGTTCTCTTC
AAAAGAGAAGTTACTCTCCCTTTTGACTGTGTAATTTTGGAAGGCTCTTGCTAAGTTACT
GAAGCCAATATTACAGGTGAAAACGTTGCAATCGGAAAGTGTCAAATACCTACTGATCAT
CACAATGATATTTTTAAATATGAATCAAGCAAATCTCACACTCTCTTCTAAGGTACTCAA
TTGATGAAGATTGAAGATGATATCTTAAAAGTAATTGTTGTAAGAACTGGTTTTGGAAGC
TACAAGGGTCAAATTATTAGAGCTTTACTTTATCCCAAGCCTTTCAATAAAAAATTCTAA
CAATAAGCTGTCAAGTTAACTATTTTAATGGCTACCCTTTTGCTTATCGGTTTCCTTTCT
ACCCTTTCTAGACTCCTTGATATTGAACTTCCTCCTTTGTTCATAGCTTTTAGATTCTTA
GATATTCTCATCTATAGTGCTCCTCCTGGTATGCCTATGCTTATCGCCATTACAAACTTC
GTTGGCTTGAAAAGATTAAAAAATAATTAGATTTTAGGATAAGATCCTAACTCTGCAAGT
TAAGCTGGTAGAATTTAAACTCTTTGCTTTGATAAGACTGGTACTCTTACTGAAGATAAG
GTTGATTTAATTGGTTACCAATTGAAAGGATAGAATCAAACATTCGATAAGATTCAATGC
TAAGATCCTAACAATATCTCAATTGAACACAAACTCTTTAGTATTTGCCATGAAGTAACA
AAAATTAACAATAAGCTTTTAGGTGATTTAATGGATGTAAAAATGGCTGAATTCAGTACT
CTCGATATAGATTACGACCATGAAGCCAAATAACACTACTCTAAATCAGGTAATAAAAGA
TTCTATTGTATCTAAGTTAACTAATTCCATTCTGAATACCAATCTATGAGTGTTGTTTGC
AAGGAAGTTGATATGATCACCAAGGAATTCAAGCATTACTTCTTCATCAAGGGATCTCCT
GAAAAGATTCAATCCTTGTCACACGTTTAATCTTCAGAAAAAGCTCAATTAAGTACCTTG
ATTAATGAAGGATACAGAATTCTTGGATTTGGTTACAAGGAAATTCCTTAAAGTGAAATA
GATGCCTTTTTAGATTTAAGCAGAGAATAACAAGAAGCCAATGTTTAATCTCTTGGTTTC
CTTATTTATAAGAATAATCTTAAACCTGACACTCAAGAAGTGATCAAAGAATTCAAAGAA
GCATGTTACAATATTAAGGTTATCTCTGGTGATAATCCAATCACTACTTTAAAAATATCC
TAAGAATTAGAAATCGTCAATAGAAAAAATCCAACAGTTATCATCAACTTTGAGGAAACT
GAAAATGTCAAGAGTCATCTTATTATCACTGAAATCTAACCTGATAACTCAACTCAAGTA
ATTGATTTCAGTTCAGCTCAAAATGAATAAGACTACATTAATAAATAAATGAGTTATTGC
TGTGATGCTTTCCTTAATAACAAATCTTTTTGTTTCAGCGGTAAAGCCCATTACTACTTC
TAGCTTAAGGCCAAGACTGACCATATTTCATTCAAGCCTGAATGGGTTAAAATGCAAGAT
AAATCTGTCTAAAAAATAATTTCTTTCTATCAAATGTTGATAATTAACACCAATGTTTTC
GCTAGAACTCAACCTGAATAAAAGCAAACTATTGTTAGACTCTTGAAAGAAAGTGACTAA
ATAGTATGTATGGTTGGTGATGGTGCAAATGACTGCTCCGCTATTCGTGAAGCAGATGTC
GGTATTTCTTTTGCTGAAGCTGATGGTTAATTCTCTTCATCCTATGTATCTTTATCAACT
TCTCTTTCCTGCGTTAAAAGAGTTTTGTTAGAAGGTAGAGTTAATTTATCTAATAGTGTA
GAAATTTTCAAGGGTTACTTACAAGTTGCACTTTTGAGATATTTAGGTTTCTTGACTTTA
GCTTACTTCTACTCATCCTACAGTAGTGGTTAAATGGATTGGTAAGCTTTAGCCTCAGGT
TACTTCTTAGTTTATTTGATATTAGGTTGCAACACACCCTTAAAGAAGCTCGAAAAGAGT
GTTTTCGATGATAACCTTTTCAGCATATATAATGTTACTTCTGTACTTTTTGGATTCACT
TTGCATATTTTGTCTATTGTTGGGTGCGTTGAAAGTCTTCATGCTAGTCCCATTTACAAG
GAAGTAAACAGCTTAGACGCTGAAAATAACTTCTAATTTGAGACTCAACACAATACTGTT
TTGAATTTCAATATTTTGATCAATTTCTTCTATGTGATTATTTCTAACCACATCGGAAAA
CCTATGAAAGATAGATATTATAAGAACACTATTGCCTATCTTATGATTTGGGGTTAATTT
ATACATGCAAATGTTATGATTTTTACAAGTTCTGCTTATCCTGGAGCATACACATCATGG
GTTGATCTTCCTGATACTACTCTTAGATTAAGAATTTTCTTCATCTCTAACGGTTTAGGT
CTACTTCTCCTTGCCTATGAACTTATTTTTGCCAGAAGAATTTTCGTTAAACTTTACACA
AGAAGTCAAGAAAGAAAAAGAGCTGCTCATATGTAATAGCTCATCGACCATATTAGAAGT
TGA

>TTHERM_00923170(gene)
ATGAGAGTTAGCTCAATTGAGGCTGAAATGGAAAACCCTATTGACGTAGATAAAACAGAC
GTAGAGGGTGAATTAAAAATTAAATAAGTCACTCTGCTCAGAGAAAATATAGTTAAAAAA
ATCGTCTTTTTCCTTGTTGCTATTTTTTGCTCCGACAGACCTAGCGTTCTAAAGAAAGTA
TTTTATGAAGAAGTATCTAAATAAGAAGAAGCCACCCATGTTTATGTTCTTGCTTCAGAT
TTGACAGATTACATAGAAGAAGCTAGCTTGAAAGAAAACCCCGAAGAAGGAGGAGAAAAG
TCTATTTATTTTGTAAACAGGCTCTAAAAGTACATCTACCACAAAAAGCAAAATAAATTT
AGAGCTATTGAATACTTTATCTAAGGCAAGTCATACTCTGAAATTGCTAATAATAAACCA
CTCGCTACAGGCAGAGTTGATCAATTGTAATAAAAATATTTCTATTTTTCTATTTCAATT
ACTCGTTATTATTTATAATAAAAAAAATACCTTCATTAAGCAAATATAGAACAGAACAGC
TTCAACGCTTTTCTTTATTAAATTCGAAATGAACAAAAATTTAATTTTATTTTAAATAAA
TTAAAAGACTCGCTTACTATGGAAAGAGTGAAATAGAAATCAATGTACCATCTTTCTTAA
CTTTAATGTGGAGAGAGTTCAAAAAACCTATTAACTTTTTACTTTATTTTGGTATCATAG
TTTGGGGTATTGAACAAATGTATGTTTCTACTGCTATTACTGTTGTTTTTACCACAACTA
TTAATTCTCTTATTTGCATTTATATTCGCGGTGTCATGTAAAAGCTAAAGGATGCCTGTC
TTAATAACACTTCTGTCATAGTATAAAGACATAATGGCTAAGGATACTAAGAAATAACAG
TAGCATCTAATATGATAGCTCCTGGTGATATAGTTCTCTTCAAAAGAGAAGTTACTCTCC
CTTTTGACTGTGTAATTTTGGAAGGCTCTTGCTAAGTTACTGAAGCCAATATTACAGGTA
ATTAATATTCTTTTAATTTTCATATATCTTATGTTTATTAAATAATTAAATTATTATTTT
ACAAAATAGGTGAAAACGTTGCAATCGGAAAGTGTCAAATACCTACTGATCATCACAATG
ATATTTTTAAGTAAAATATTTAATAACTTTAATTCTCAACTAATTATTAAATTAATTTTT
CATAATAAAAATAGATATGAATCAAGCAAATCTCACACTCTCTTCTAAGGTACTCAATTG
ATGAAGATTGAAGATGATATCTTAAAAGTAATTGTTGTAAGAACTGGTTTTGGAAGCTAC
AAGGGTCAAATTATTAGAGCTTTACTTTATCCCAAGCCTTTCAATAAAAAATTCTAACAA
TAAGCTGTCAAGTTAACTATTTTAATGGCTACCCTTTTGCTTATCGGTTTCCTTTCTACC
CTTTCTAGACTCCTTGATATTGAACTTCCTCCTTTGTTCATAGCTTTTAGATTCTTAGAT
ATTCTCATCTATAGTGCTCCTCCTGGTATGCCTATGCTTATCGCCATTACAAACTTCGTT
GGCTTGAAAAGATTAAAAAATAATTAGATTTTAGGATAAGATCCTAACTCTGCAAGTTAA
GCTGGTAGAATTTAAACTCTTTGCTTTGATAAGACTGGTACTCTTACTGAAGATAAGGTT
GATTTAATTGGTTACCAATTGAAAGGATAGAATCAAACATTCGATAAGATTCAATGCTAA
GATCCTAACAATATCTCAATTGAACACAAACTCTTTAGTATTTGCCATGAAGTAACAAAA
ATTAACAATAAGCTTTTAGGTGATTTAATGGATGTAAAAATGGCTGAATTCAGTACTCTC
GATATAGATTACGACCATGAAGCCAAATAACACTACTCTAAATCAGGTAATAAAAGATTC
TATTGTATCTAAGTTAACTAATTCCATTCTGAATACCAATCTATGAGTGTTGTTTGCAAG
GAAGTTGATATGATCACCAAGGAATTCAAGCATTACTTCTTCATCAAGGGATCTCCTGAA
AAGATTCAATCCTTGTCACACGTTTAATCTTCAGAAAAAGCTCAATTAAGTACCTTGATT
AATGAAGGATACAGAATTCTTGGATTTGGTTACAAGGAAATTCCTTAAAGTGAAATAGAT
GCCTTTTTAGATTTAAGCAGAGAATAACAAGAAGCCAATGTTTAATCTCTTGGTTTCCTT
ATTTATAAGAATAATCTTAAACCTGACACTCAAGAAGTGATCAAAGAATTCAAAGAAGCA
TGTTACAATATTAAGGTTATCTCTGGTGATAATCCAATCACTACTTTAAAAATATCCTAA
GAATTAGAAATCGTCAATAGAAAAAATCCAACAGTTATCATCAACTTTGAGGAAACTGAA
AATGTCAAGAGTCATCTTATTATCACTGAAATCTAACCTGATAACTCAACTCAAGTAATT
GATTTCAGTTCAGCTCAAAATGAATAAGACTACATTAATAAATAAATGAGTTATTGCTGT
GATGCTTTCCTTAATAACAAATCTTTTTGTTTCAGCGGTAAAGCCCATTACTACTTCTAG
CTTAAGGCCAAGACTGACCATATTTCATTCAAGCCTGAATGGGTTAAAATGCAAGATAAA
TCTGTCTAAAAAATAATTTCTTTCTATCAAATGTTGATAATTAACACCAATGTTTTCGCT
AGAACTCAACCTGAATAAAAGCAAACTATTGTTAGACTCTTGAAAGAAAGTGACTAAATA
GTATGTATGGTTGGTGATGGTGCAAATGACTGCTCCGCTATTCGTGAAGCAGATGTCGGT
ATTTCTTTTGCTGAAGCTGATGGTTAATTCTCTTCATCCTATGTATCTTTATCAACTTCT
CTTTCCTGCGTTAAAAGAGTTTTGTTAGAAGGTAGAGTTAATTTATCTAATAGTGTAGAA
ATTTTCAAGGGTTACTTACAAGTTGCACTTTTGAGATATTTAGGTTTCTTGACTTTAGCT
TACTTCTACTCATCCTACAGTAGTGGTTAAATGGATTGGTAAGCTTTAGCCTCAGGTTAC
TTCTTAGTTTATTTGATATTAGGTTGCAACACACCCTTAAAGAAGCTCGAAAAGAGTGTT
TTCGATGATAACCTTTTCAGCATATATAATGTTACTTCTGTACTTTTTGGATTCACTTTG
CATATTTTGTCTATTGTTGGGTGCGTTGAAAGTCTTCATGCTAGTCCCATTTACAAGGAA
GTAAACAGCTTAGACGCTGAAAATAACTTCTAATTTGAGACTCAACACAATACTGTTTTG
AATTTCAATATTTTGATCAATTTCTTCTATGTGATTATTTCTAACCACATCGGAAAACCT
ATGAAAGATAGATATTATAAGAACACTATTGCCTATCTTATGATTTGGGGTTAATTTATA
CATGCAAATGTTATGATTTTTACAAGTTCTGCTTATCCTGGAGCATACACATCATGGGTT
GATCTTCCTGATACTACTCTTAGATTAAGAATTTTCTTCATCTCTAACGGTTTAGGTCTA
CTTCTCCTTGCCTATGAACTTATTTTTGCCAGAAGAATTTTCGTTAAACTTTACACAAGA
AGTCAAGAAAGAAAAAGAGCTGCTCATATGTAATAGCTCATCGACCATATTAGAAGTTGA

>TTHERM_00923170(protein)
MRVSSIEAEMENPIDVDKTDVEGELKIKQVTLLRENIVKKIVFFLVAIFCSDRPSVLKKV
FYEEVSKQEEATHVYVLASDLTDYIEEASLKENPEEGGEKSIYFVNRLQKYIYHKKQNKF
RAIEYFIQGKSYSEIANNKPLATGRVDQLLAYYGKSEIEINVPSFLTLMWREFKKPINFL
LYFGIIVWGIEQMYVSTAITVVFTTTINSLICIYIRGVMQKLKDACLNNTSVIVQRHNGQ
GYQEITVASNMIAPGDIVLFKREVTLPFDCVILEGSCQVTEANITGENVAIGKCQIPTDH
HNDIFKYESSKSHTLFQGTQLMKIEDDILKVIVVRTGFGSYKGQIIRALLYPKPFNKKFQ
QQAVKLTILMATLLLIGFLSTLSRLLDIELPPLFIAFRFLDILIYSAPPGMPMLIAITNF
VGLKRLKNNQILGQDPNSASQAGRIQTLCFDKTGTLTEDKVDLIGYQLKGQNQTFDKIQC
QDPNNISIEHKLFSICHEVTKINNKLLGDLMDVKMAEFSTLDIDYDHEAKQHYSKSGNKR
FYCIQVNQFHSEYQSMSVVCKEVDMITKEFKHYFFIKGSPEKIQSLSHVQSSEKAQLSTL
INEGYRILGFGYKEIPQSEIDAFLDLSREQQEANVQSLGFLIYKNNLKPDTQEVIKEFKE
ACYNIKVISGDNPITTLKISQELEIVNRKNPTVIINFEETENVKSHLIITEIQPDNSTQV
IDFSSAQNEQDYINKQMSYCCDAFLNNKSFCFSGKAHYYFQLKAKTDHISFKPEWVKMQD
KSVQKIISFYQMLIINTNVFARTQPEQKQTIVRLLKESDQIVCMVGDGANDCSAIREADV
GISFAEADGQFSSSYVSLSTSLSCVKRVLLEGRVNLSNSVEIFKGYLQVALLRYLGFLTL
AYFYSSYSSGQMDWQALASGYFLVYLILGCNTPLKKLEKSVFDDNLFSIYNVTSVLFGFT
LHILSIVGCVESLHASPIYKEVNSLDAENNFQFETQHNTVLNFNILINFFYVIISNHIGK
PMKDRYYKNTIAYLMIWGQFIHANVMIFTSSAYPGAYTSWVDLPDTTLRLRIFFISNGLG
LLLLAYELIFARRIFVKLYTRSQERKRAAHMQQLIDHIRS