Identifiers and Description

Gene Model Identifier

TTHERM_00938820

Standard Name

EEF2 (Eukaryotic translation Elongation Factor )

Aliases

PreTt03732 | 170.m00104

Description

EEF2 elongation factor 2 putative; Translation elongation factor 2; catalyzes ribosomal translocation during protein synthesis; mRNA is expressed during vegetative growth; high amino acid identity with EF-2 in other eukaryotes

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Cellular Component

• cytoplasm (IC) | GO:0005737

Molecular Function

• GTP binding (IEA) | GO:0005525
• GTPase activity (IEA) | GO:0003924

Domains

• ( PF00009 ) Elongation factor Tu GTP binding domain
• ( PF00679 ) Elongation factor G C-terminus
• ( PF01926 ) 50S ribosome-binding GTPase
• ( PF03144 ) Elongation factor Tu domain 2
• ( PF03764 ) Elongation factor G, domain IV
• ( PF08477 ) Ras of Complex, Roc, domain of DAPkinase
• ( TIGR00231 ) small GTP-binding protein domain
• ( TIGR00475 ) selenocysteine-specific translation elongation factor
• ( TIGR00483 ) translation elongation factor EF-1, subunit
• ( TIGR00484 ) translation elongation factor G
• ( TIGR00485 ) translation elongation factor Tu
• ( TIGR00490 ) translation elongation factor aEF-2
• ( TIGR00503 ) peptide chain release factor 3
• ( TIGR01393 ) GTP-binding protein LepA
• ( TIGR01394 ) GTP-binding protein TypA/BipA

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Stentor Coeruleus	SteCoe_7852	0
	Description: None
WormBase	WBGene00001167	9.997093137033517e-262
	Description: locus:eef-2 Elongation factor 2 status:Confirmed UniProt:P29691 protein_id:CAB02985.1
Tetrahymena borealis	EI9_19363.1	9.997093137033517e-262
	Description: elongation factor G, domain IV family protein (839 aa)
DictyBase	DDB_G0288373	9.997093137033517e-262
	Description: efbA on chromosome: 5 position 1470619 to 1473138
Oxytricha	Contig22552.0.g51	9.997093137033517e-262
	Description: Elongation factor Tu GTP binding domain
SGD	YOR133W	9.997093137033517e-262
	Description: EFT1 Elongation factor 2 (EF-2), also encoded by EFT2; catalyzes ribosomal translocation during protein synthesis; contains diphthamide, the unique posttranslationally modified histidine residue specifically ADP-ribosylated by diphtheria toxin
WormBase	WBGene00019428	9.997093137033517e-262
	Description: locus:dgk-5 Putative diacylglycerol kinase K06A1.6 status:Partially_confirmed UniProt:Q10024 protein_id:CCD72614.1
Tetrahymena borealis	EI9_18515.1	9.997093137033517e-262
	Description: hypothetical protein (1320 aa)

General Information

No Data fetched for General Information

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_00938820(coding)
ATGGTTAACTTCACTGTTGAATAAATTAGATAGATTATGGATAACTAAGACAATATCCGT
AATATGTCAGTTATTGCTCACGTCGATCACGGTAAATCCACCCTTACCGATTCCTTGATT
TGCAAGGCCGGTATTATTTCTTCTAAGGCTGCTGGTGAAGCTAGATACACCGATACCAGA
GATGATGAAAAGGAAAGAGGTATTACCATTAAGTCCACTGGTGTCTCTATGTATTACGAA
TATGATTTGAACGAAACTGGTAAGTAAGAACCTTACTTGTTGAACTTGATCGATTCTCCG
GGACACGTCGATTTCTCCTCTGAAGTTACTGCTGCTTTGAGAGTTACTGATGGTGCTTTG
GTCGTCGTCGATTGCGTTGAAGGTGTTTGCGTCCAAACCGAAACCGTCTTAAGACAAGCC
ATGCAAGAAAAGATTAAGCCCGTCCTTATCGTTAACAAGATTGATAGATCTATCTTGGAA
TTAAAGCACGATGGTGAAACCATGTATCAAAATTTCATTAGAGTTATTGATATGGTCAAC
GTTATCATCGATACTTACAACCAAGAAGATATGGGTCCCCTCCTCGTTCAACCCGATGAA
GGTTCCGTCGCTTTCGGTTCTGGTAAGGAATGTTGGGCTTTCACTTTGACCAAGTTCTCC
AGAATCTATGCCAAGAAGTTCGGTATTGATAAAAATAAAATGATGAAGAAGTTGTGGGGT
GACAATTTCTTCGATGCTGCTTCCAAGAAGTGGACCAACAACAACGTTAGTGACAATGGT
ACTCCCTTGAAGAGAGCTTTCGCTTAATTCATTATGGATCCCATTTGCAAGCTTGCTAAC
GCCGTTATGGATAACGATATGGAATTGATGGACAAGATGCTCAAGACTCTCGAACTCACT
CTTACTCAAGAAGACAGAGACCTCAAGGGTAAGCACCTCCTCAAGGCTGTCATGTCTAAG
TGGTTGAACGCTGCTGATACTATCTTAGAAATGATGGTTATCCATTTACCCTCCCCCAGA
AAAGCTTAATAATACAGAACTTCTTATCTTTACGAAGGTCCCCAAGATGATGATATCGCC
AAGGCCATGAAGGCTTGCGATCCCAAGGGTCCTCTTATGATGTACGTCTCTAAGATGGTT
CCCACCGCTGATAAGGGTAGATTCGTCGCTTTCGGTAGAGTTTTCTCTGGTACTATTGCT
ACCTCCCAAAAGGTTAGAATCCTTGGTCCCAACTATCAACCTGGTAAGAAGGAAGATCTC
CACGAAAAGACCCTCCAAAGAACTCTTATTATGTAAGGTAGAACTACCGAATACATTCCC
GATGTTCCTTGCGGTAACACCGTCGGTTTGGTTGGTGTCGATCAATTCATCTTGAAGACC
GGTACCATTACTGATCACCCCGATGCTCACACCATCAGATCCATGAAATACTCCGTCTCT
CCTGTCGTCAGAGTTGCCGTTAATGTTAAAAACGCTGGTGATCTTCCCAAGCTCGTCGAT
GGTTTGAAGAAGCTCTCCAAGTCTGATCCTTTAGTCATCTGTACCACTGAAGAATCTACT
GGTCAACACATTATTGCTGGTTGCGGTGAATTGCACATTGAAATTTGCTTAAAGGATCTT
GAAGAAGATTACGCTAACTGCCCCATCATTAAATCCGACCCCGTCGTCACCTATAAGGAA
ACTGTTACTGCTGAATCTAACATTACTTGTATGTCCAAGTCTGCTAACAAGCACAACAGA
ATCTACGCTAAGGGTGCTCCTCTTGAAGATGGTCTCGCTGAAGACATCGAAAAGGGTACC
ATTAACCCCAAGGACGATCCTAAGGACAGAGCTAAACTCTTAAACGAAAAATACAATTGG
GACAGAACTGAAGCCGGTACTAAGCTCTGGTCTTTCGGTCCTGAAAACGTTGGTCCTAAC
TTGGTTGTTGATCAAACTAAGGGTATCCAATACGTCAACGAAATTAAGGACTCCGTTGAA
TCTGCCTGGTAATGGGCCTCCAAGGAAGCTGTCATGACTGAAGAAGGTATGAGAGGTGTC
AGAATGAACCTCCTCGATTGCGTTCTCCACGCTGATGCTATCCACAGAGGTGCTGGTCAA
ATTCTCCCCACCGCTAGAAGACTCTTCTACGCTTGTGAACTTACTGCTGAACCCAGACTC
CAAGAACCCATCTTCACTGCTGAAATTACTGCTCCTCAAGATGCTATGGGTGGTGTTTAC
AACTGTCTCAACTAGAGAAGAGGTATCATCAACGAAGAAGAATAAGTTTAGGGTACTCCT
ATGGCTATTGTCAAGGCTTACTTACCTGTCGCTGAATCCTTCGGTTTCACCGCTCACTTA
AGAGGTCTTACTCAAGGTCAAGCTTTCCCTCAATGTTTCTTCGATCATTGGGCCACCATT
AGTGGTTCTCCCTTCGAAGCTAACTCCAAGGCTGCTGACATCGTTAATAACATCAGAAAG
AGAAAGGGTCTTAAGGAAGGTATCCCTGATCTTAACAACTACTTGGATAAGCTATGA

>TTHERM_00938820(gene)
ATGGTTAACTTCACTGTTGAATAAATTAGATAGATTATGGATAACTAAGACAATATCCGT
AATATGTCAGTTATTGCTCACGTCGATCACGGTAAATCCACCCTTACCGATTCCTTGATT
TGCAAGGCCGGTATTATTTCTTCTAAGGCTGCTGGTGAAGCTAGATACACCGATACCAGA
GATGATGAAAAGGAAAGAGGTATTACCATTAAGTCCACTGGTGTCTCTATGTATTACGAA
TATGATTTGAACGAAACTGGTAAGTAAGAACCTTACTTGTTGAACTTGATCGATTCTCCG
GGACACGTCGATTTCTCCTCTGAAGTTACTGCTGCTTTGAGAGTTACTGATGGTGCTTTG
GTCGTCGTCGATTGCGTTGAAGGTGTTTGCGTCCAAACCGAAACCGTCTTAAGACAAGCC
ATGCAAGAAAAGATTAAGCCCGTCCTTATCGTTAACAAGATTGATAGATCTATCTTGGAA
TTAAAGCACGATGGTGAAACCATGTATCAAAATTTCATTAGAGTTATTGATATGGTCAAC
GTTATCATCGATACTTACAACCAAGAAGATATGGGTCCCCTCCTCGTTCAACCCGATGAA
GGTTCCGTCGCTTTCGGTTCTGGTAAGGAATGTTGGGCTTTCACTTTGACCAAGTTCTCC
AGAATCTATGCCAAGAAGTTCGGTATTGATAAAAATAAAATGATGAAGAAGTTGTGGGGT
GACAATTTCTTCGATGCTGCTTCCAAGAAGTGGACCAACAACAACGTTAGTGACAATGGT
ACTCCCTTGAAGAGAGCTTTCGCTTAATTCATTATGGATCCCATTTGCAAGCTTGCTAAC
GCCGTTATGGATAACGATATGGAATTGATGGACAAGATGCTCAAGACTCTCGAACTCACT
CTTACTCAAGAAGACAGAGACCTCAAGGGTAAGCACCTCCTCAAGGCTGTCATGTCTAAG
TGGTTGAACGCTGCTGATACTATCTTAGAAATGATGGTTATCCATTTACCCTCCCCCAGA
AAAGCTTAATAATACAGAACTTCTTATCTTTACGAAGGTCCCCAAGATGATGATATCGCC
AAGGCCATGAAGGCTTGCGATCCCAAGGGTCCTCTTATGATGTACGTCTCTAAGATGGTT
CCCACCGCTGATAAGGGTAGATTCGTCGCTTTCGGTAGAGTTTTCTCTGGTACTATTGCT
ACCTCCCAAAAGGTTAGAATCCTTGGTCCCAACTATCAACCTGGTAAGAAGGAAGATCTC
CACGAAAAGACCCTCCAAAGAACTCTTATTATGTAAGGTAGAACTACCGAATACATTCCC
GATGTTCCTTGCGGTAACACCGTCGGTTTGGTTGGTGTCGATCAATTCATCTTGAAGACC
GGTACCATTACTGATCACCCCGATGCTCACACCATCAGATCCATGAAATACTCCGTCTCT
CCTGTCGTCAGAGTTGCCGTTAATGTTAAAAACGCTGGTGATCTTCCCAAGCTCGTCGAT
GGTTTGAAGAAGCTCTCCAAGTCTGATCCTTTAGTCATCTGTACCACTGAAGAATCTACT
GGTCAACACATTATTGCTGGTTGCGGTGAATTGCACATTGAAATTTGCTTAAAGGATCTT
GAAGAAGATTACGCTAACTGCCCCATCATTAAATCCGACCCCGTCGTCACCTATAAGGAA
ACTGTTACTGCTGAATCTAACATTACTTGTATGTCCAAGTCTGCTAACAAGCACAACAGA
ATCTACGCTAAGGGTGCTCCTCTTGAAGATGGTCTCGCTGAAGACATCGAAAAGGGTACC
ATTAACCCCAAGGACGATCCTAAGGACAGAGCTAAACTCTTAAACGAAAAATACAATTGG
GACAGAACTGAAGCCGGTACTAAGCTCTGGTCTTTCGGTCCTGAAAACGTTGGTCCTAAC
TTGGTTGTTGATCAAACTAAGGGTATCCAATACGTCAACGAAATTAAGGACTCCGTTGAA
TCTGCCTGGTAATGGGCCTCCAAGGAAGCTGTCATGACTGAAGAAGGTATGAGAGGTGTC
AGAATGAACCTCCTCGATTGCGTTCTCCACGCTGATGCTATCCACAGAGGTGCTGGTCAA
ATTCTCCCCACCGCTAGAAGACTCTTCTACGCTTGTGAACTTACTGCTGAACCCAGACTC
CAAGAACCCATCTTCACTGCTGAAATTACTGCTCCTCAAGATGCTATGGGTGGTGTTTAC
AACTGTCTCAACTAGAGAAGAGGTATCATCAACGAAGAAGAATAAGTTTAGGGTACTCCT
ATGGCTATTGTAACAATTTATTTCCCTTTTCTATCAAAATTTTAAAAATTCAATTTACTC
TCAATAAACAATTTATTTAAATATATTTTTTAATTCTATAGGTCAAGGCTTACTTACCTG
TCGCTGAATCCTTCGGTTTCACCGCTCACTTAAGAGGTCTTACTCAAGGTCAAGCTTTCC
CTCAATGTTTCTTCGATCATTGGGCCACCATTAGTGGTTCTCCCTTCGAAGCTAACTCCA
AGGCTGCTGACATCGTTAATAACATCAGAAAGAGAAAGGGTCTTAAGGAAGGTATCCCTG
ATCTTAACAACTACTTGGATAAGCTATGA

>TTHERM_00938820(protein)
MVNFTVEQIRQIMDNQDNIRNMSVIAHVDHGKSTLTDSLICKAGIISSKAAGEARYTDTR
DDEKERGITIKSTGVSMYYEYDLNETGKQEPYLLNLIDSPGHVDFSSEVTAALRVTDGAL
VVVDCVEGVCVQTETVLRQAMQEKIKPVLIVNKIDRSILELKHDGETMYQNFIRVIDMVN
VIIDTYNQEDMGPLLVQPDEGSVAFGSGKECWAFTLTKFSRIYAKKFGIDKNKMMKKLWG
DNFFDAASKKWTNNNVSDNGTPLKRAFAQFIMDPICKLANAVMDNDMELMDKMLKTLELT
LTQEDRDLKGKHLLKAVMSKWLNAADTILEMMVIHLPSPRKAQQYRTSYLYEGPQDDDIA
KAMKACDPKGPLMMYVSKMVPTADKGRFVAFGRVFSGTIATSQKVRILGPNYQPGKKEDL
HEKTLQRTLIMQGRTTEYIPDVPCGNTVGLVGVDQFILKTGTITDHPDAHTIRSMKYSVS
PVVRVAVNVKNAGDLPKLVDGLKKLSKSDPLVICTTEESTGQHIIAGCGELHIEICLKDL
EEDYANCPIIKSDPVVTYKETVTAESNITCMSKSANKHNRIYAKGAPLEDGLAEDIEKGT
INPKDDPKDRAKLLNEKYNWDRTEAGTKLWSFGPENVGPNLVVDQTKGIQYVNEIKDSVE
SAWQWASKEAVMTEEGMRGVRMNLLDCVLHADAIHRGAGQILPTARRLFYACELTAEPRL
QEPIFTAEITAPQDAMGGVYNCLNQRRGIINEEEQVQGTPMAIVKAYLPVAESFGFTAHL
RGLTQGQAFPQCFFDHWATISGSPFEANSKAADIVNNIRKRKGLKEGIPDLNNYLDKL