Identifiers and Description

Gene Model Identifier

TTHERM_00962190

Standard Name

AMT4 (Adenine MethylTransferase (AMT) 4 targeting position N-six of Adenine, homolog of budding yeast IME)

Aliases

PreTt23707 | 178.m00088 | TRAM-4

Description

IME4 N6-adenosine-methyltransferase 70 kDa subunit; In yeast- required for entry into meiosis MT-A70 family protein

Genome Browser (Macronucleus)

Full Screen View


Genome Browser (Micronucleus)

Full Screen View

External Links

Gene Ontology Annotations

Molecular Function

Biological Process

  • nucleobase-containing compound metabolic process (IEA) | GO:0006139

Domains

  • ( PF05063 ) MT-A70
  • ( PF08648 ) U4/U6.U5 small nuclear ribonucleoproteins

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source Identifier Score
Tetrahymena borealis EI9_15839.1 9.997093137033517e-262
Description: MT-A70 family protein (754 aa)
SGD YGL192W 1.0002434920975502e-91
Description: IME4 Probable mRNA N6-adenosine methyltransferase required for entry into meiosis; transcribed in diploid cells; haploids repress IME4 transcription via production of antisense IME4 transcripts; antisense transcription is repressed in diploids
Oxytricha Contig17486.0.g100 9.00381557957642e-37
Description: MT-A70
Stentor Coeruleus SteCoe_21805 2.3195228302435696e-16
Description: None

General Information

No Data fetched for General Information

Associated Literature

  1. Ref:31722409: Wang Y, Sheng Y, Liu Y, Zhang W, Cheng T, Duan L, Pan B, Qiao Y, Liu Y, Gao S (2019) A distinct class of eukaryotic MT-A70 methyltransferases maintain symmetric DNA N6-adenine methylation at the ApT dinucleotides as an epigenetic mark associated with transcription. Nucleic acids research 47(22):11771-11789

Sequences 

>TTHERM_00962190(coding)
ATGGGAAGCTCTGTAAAAGATTAGGAAATATCAAATAAAAAGCACAAGGCTCGTAATTCT
AGCAGTGGAGCCAATAACAATAGCAATAGCAGTAATTATTAAAGCAGTAAAAGAGACATT
CATTAAGACCGCAGTTATTCGAAGGATGACAGTCAAAGCAGGTAATACAATAGTAACAAC
GGCGGCGGAGGATCAAGCTCTAAAAATAGCAATCGTAACTCATCACAATAGGGTTATAAT
TAGAATTCTTCATCAAATCAAGGATAGAATTCCGAATATGGAGGATCTGGTTCAGGGAAA
AATTCTTAAGCAAATTCATAGAGAAATTCCTCTTAATAAGGATTGTAGTAGTTAAATTAG
CAGTAGTAATCTTAGCAATAATAGCAATAGATGCTTTAAAATTAAATGAATTCTATGGGA
ATGATGAATTAATTTTAGAACAGTTTTGGCTTGATGGGAATGTAGCCATCTTAGCCTTTA
CAGCTATTAAATCCTAGCATGATTATTCCTTCTGGAAAAAAATAAAAATATGATTTTCTT
GAGTTTCCACCATCCAGTTAGCATGAATTTCGCGCAATTTTATTAGATTATTTTTTGAGT
GATTTATTTGATTACCCAATGCACTCAGCTGAGTTGTTTGAGAATTTCATAGAGGCCTTC
AGTGATATTAAAGATTCTTCTTCATTTATTAAGAAATTAGAATTAATACCTTTGTTACAA
GAATTAAATGACAAGAAAGCCATCAAGCTAGAAACATGTGCTGTCGGAACTAAATTGTTT
GATTTCATCGTAGATATTAACAAGGATAAAATTAAATAACTATCAAGAGAATTTTCGAAA
GATAGACCAAAGTTCATGCCTATCCTTGATAAAAAGCCTCAACCTTCCTCTTCAAAGACA
AATAGCAGCTCAACAACAGCTCCACCAAAACAAGCAATATCAAAAAGAGAAATCGAAGAT
TTATTAAAGAAAGAAACGGGTCTTCAAAAGGAAGTTATTACACAAAGTAAAGAAAAAAGC
AATTTATTGAATAAGATTTCAGCAGCAGAAGAATCTGCATTAGCTATTTTCAGAAAGTAA
GGCTCTAGAAGAATAGATTACTGTGATTGTGGTACAAGAGATAAGTGTATATAAATAAGA
AATTCCACAGTGCCTTGCAACAAAGCGCACTTCAGAAAGATAATTCGTCCTCATACAGAT
GAAAATTTAGGAAACTGTTCTTATTTAGATACTTGCAGGCATATGGATTACTGCAAATTC
GTTCATTATGAATTAGATGTGGATATAAATAACATGAATAACGATAATCTTTTGCTAGAT
GGAATTGAAAAAAAACTCAATCCTTAATGGATTAACTGCGATCTAAGACAAATAGATTTT
AATATTTTGGGTAAATTCAACTGTATAATGGCTGATCCTCCTTGGGATATTCATATGACT
CTTCCTTATGGTACATTGAAAGATAGAGAAATGAAAGCAATGAGAGTTGATTTACTTCAA
GAGGAAGGTGTTATCTTTTTATGGGTAACTGGCCGTGCTATGGAACTTGGTAGAGAGTGC
TTAACTAATTGGGGATATAGAAGAGTTGAAGAAATTATTTGGGTAAAAACAAATTAATTG
CAAAGAATTATAAGAACAGGAAGAACAGGCCACTGGCTGAACCACTCTAAAGAACATTGT
CTTGTAGGAATTAAAGGTAATCCTAAGATAAATAGAAAAATCGACTGTGATGTGATAGTC
TCAGAAGTTAGAGAAACAAGTAGAAAACCAGATGAGATTTACAATTTAATAGAAAGAATG
TGTCCTGGAGGGAAAAAAATAGAATTATTTGGTAGACCACACAACACTATGCCAGGTTGG
CTAACTCTTGGTAATTAGTTACCAGGAATTTATTTAGAAGATGAGGAAATTATAGAAAGA
TATATGGATGCTTATCCTGATTAAGATATAAGCAGAGAAACAATGGAAAGAAATAGAATT
AGAATGAAAAATGAAAATGATATTGACCATATTTATAATTCACATATACAAAATATTCCT
CCTTTTAAAACTAAATAGCTAACAAAAGATTTGCAACTTCAACAATAAAGCAGTAGTATG
CAAACTACTTAATAGTAAAGTAGTTCACAGATGATGCCTCAAATGTAATAACAGTAATCT
TCGCAATCTATAAACTCCAACACCGATTTATAAATGCATGGAAACGGATTGTACGAGCAA
GAATGA


>TTHERM_00962190(gene)
ATGGGAAGCTCTGTAAAAGATTAGGAAATATCAAATAAAAAGCACAAGGCTCGTAATTCT
AGCAGTGGAGCCAATAACAATAGCAATAGCAGTAATTATTAAAGCAGTAAAAGAGACATT
CATTAAGACCGCAGTTATTCGAAGGATGACAGTCAAAGCAGGTAATACAATAGTAACAAC
GGCGGCGGAGGATCAAGCTCTAAAAATAGCAATCGTAACTCATCACAATAGGGTTATAAT
TAGAATTCTTCATCAAATCAAGGATAGAATTCCGAATATGGAGGATCTGGTTCAGGGAAA
AATTCTTAAGCAAATTCATAGAGAAATTCCTCTTAATAAGGATTGTAGTAGTTAAATTAG
CAGTAGTAATCTTAGCAATAATAGCAATAGATGCTTTAAAATTAAATGAATTCTATGGGA
ATGATGAATTAATTTTAGAACAGTTTTGGCTTGATGGGAATGTAGCCATCTTAGCCTTTA
CAGCTATTAAATCCTAGCATGATTATTCCTTCTGGAAAAAAATAAAAATATGATTTTCTT
GAGTTTCCACCATCCAGTTAGCATGAATTTCGCGCAATTTTATTAGATTATTTTTTGAGT
GATTTATTTGATTACCCAATGCACTCAGCTGAGTTGTTTGAGAATTTCATAGAGGCCTTC
AGTGATATTAAAGATTCTTCTTCATTTATTAAGAAATTAGAATTAATACCTTTGTTACAA
GAATTAAATGACAAGAAAGCCATCAAGCTAGAAACATGTGCTGTCGGAACTAAATTGTTT
GATTTCATCGTAGATATTAACAAGGATAAAATTAAATAACTATCAAGAGAATTTTCGAAA
GATAGACCAAAGTTCATGCCTATCCTTGATAAAAAGCCTCAACCTTCCTCTTCAAAGACA
AATAGCAGCTCAACAACAGCTCCACCAAAACAAGCAATATCAAAAAGAGTATTTTTTACA
AAAATTTATATTGATTAATATAAATGTTATTTGTTAGTTTGTTCGCTCTAAGTATGACAA
TTTATTTACTTATTAAAAGGAAATCGAAGATTTATTAAAGAAAGAAACGGGTCTTCAAAA
GGAAGTTATTACACAAAGTAAAGAAAAAAGCAATTTATTGAATAAGATTTCAGCAGCAGA
AGAATCTGCATTAGCTATTTTCAGAAAGTAAGGCTCTAGAAGAATAGATTACTGTGATTG
TGGTACAAGAGATAAGTGTATATAAATAAGAAATTCCACAGTGCCTTGCAACAAAGCGCA
CTTCAGAAAGATAATTCGTCCTCATACAGATGAAAATTTAGGAAACTGTTCTTATTTAGA
TACTTGCAGGCATATGGATTACTGCAAATTCGTTCATTATGAATTAGATGTGGATATAAA
TAACATGAATAACGATAATCTTTTGCTAGATGGAATTGAAAAAAAACTCAATCCTTAATG
GATTAACTGCGATCTAAGACAAATAGATTTTAATATTTTGGGTAAATTCAACTGTATAAT
GGCTGATCCTCCTTGGGATATTCATATGACTCTTCCTTATGGTACATTGAAAGTAAGAAA
TAAATTAATATAAGTTATTGCTTTAAAATCTATTCAGAATTTTCGATGGGATATATTCAT
TTAATAATATGAAAGTTCATTAATGAGTTTGAAAATATAGCAGAAAGCTACATTTTCTTT
TAAGATATTCGCAATAGAATTAGATATTAATTAAAATAGTTGCATTTTATTTGTTTTAAA
GTTAGATTTTACAAAACTCCTTTTAACAATGAAATAGCTTTTAAATGAAGAAATTAATGA
AATTTTATTTACTTATTTTTATAAATAATAAAAGGATAGAGAAATGAAAGCAATGAGAGT
TGATTTACTTCAAGAGGAAGGTGTTATCTTTTTATGGGTAACTGGCCGTGCTATGGAACT
TGGTAGAGAGTGCTTAACTAATTGGGGATATAGAAGAGTTGAAGAAATTATTTGGGTAAA
AACAAATTAATTGCAAAGAATTATAAGAACAGGAAGAACAGGCCACTGGCTGAACCACTC
TAAAGAACATTGTCTTGTAGGAATTAAAGGTAATCCTAAGATAAATAGAAAAATCGACTG
TGATGTGATAGTCTCAGAAGTTAGAGAAACAAGTAGAAAACCAGATGAGATTTACAATTT
AATAGAAAGAATGTGTCCTGGAGGGAAAAAAATAGAATTATTTGGTAGACCACACAACAC
TATGCCAGGTTGGCTAACTCTTGGTAATTAGTTACCAGGAATTTATTTAGAAGATGAGGA
AATTATAGAAAGATATATGGATGCTTATCCTGATTAAGATATAAGCAGAGAAACAATGGA
AAGAAATAGAATTAGAATGAAAAATGAAAATGATATTGACCATATTTATAATTCACATAT
ACAAAATATTCCTCCTTTTAAAACTAAATAGCTAACAAAAGATTTGCAACTTCAACAATA
AAGCAGTAGTATGCAAACTACTTAATAGTAAAGTAGTTCACAGATGATGCCTCAAATGTA
ATAACAGTAATCTTCGCAATCTATAAACTCCAACACCGATTTATAAATGTAAGCTTTTCA
CATGATTTCATCAGAATTTCTAAGATTATCTTTTTCGAAAAAAGGCATGGAAACGGATTG
TACGAGCAAGAATGA


>TTHERM_00962190(protein)
MGSSVKDQEISNKKHKARNSSSGANNNSNSSNYQSSKRDIHQDRSYSKDDSQSRQYNSNN
GGGGSSSKNSNRNSSQQGYNQNSSSNQGQNSEYGGSGSGKNSQANSQRNSSQQGLQQLNQ
QQQSQQQQQQMLQNQMNSMGMMNQFQNSFGLMGMQPSQPLQLLNPSMIIPSGKKQKYDFL
EFPPSSQHEFRAILLDYFLSDLFDYPMHSAELFENFIEAFSDIKDSSSFIKKLELIPLLQ
ELNDKKAIKLETCAVGTKLFDFIVDINKDKIKQLSREFSKDRPKFMPILDKKPQPSSSKT
NSSSTTAPPKQAISKREIEDLLKKETGLQKEVITQSKEKSNLLNKISAAEESALAIFRKQ
GSRRIDYCDCGTRDKCIQIRNSTVPCNKAHFRKIIRPHTDENLGNCSYLDTCRHMDYCKF
VHYELDVDINNMNNDNLLLDGIEKKLNPQWINCDLRQIDFNILGKFNCIMADPPWDIHMT
LPYGTLKDREMKAMRVDLLQEEGVIFLWVTGRAMELGRECLTNWGYRRVEEIIWVKTNQL
QRIIRTGRTGHWLNHSKEHCLVGIKGNPKINRKIDCDVIVSEVRETSRKPDEIYNLIERM
CPGGKKIELFGRPHNTMPGWLTLGNQLPGIYLEDEEIIERYMDAYPDQDISRETMERNRI
RMKNENDIDHIYNSHIQNIPPFKTKQLTKDLQLQQQSSSMQTTQQQSSSQMMPQMQQQQS
SQSINSNTDLQMHGNGLYEQE