Identifiers and Description

Gene Model Identifier

TTHERM_00962200

Standard Name

Impβ6 (Importin-beta 6)

Aliases

PreTt23708 | 178.m00089 | ImpB6

Description

Importin-beta amine-terminal domain protein; Importin-beta N-terminal domain containing protein. Co-purifies with Asf1

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Molecular Function

• obsolete protein transporter activity (IEA) | GO:0008565

Biological Process

• intracellular protein transport (IEA) | GO:0006886

Domains

• ( PF02985 ) HEAT repeat
• ( PF03002 ) Somatostatin/Cortistatin family
• ( PF03810 ) Importin-beta N-terminal domain
• ( PF05316 ) Mitochondrial ribosomal protein (VAR1)
• ( PF07671 ) Protein of unknown function (DUF1601)
• ( PF08506 ) Cse1
• ( PF09292 ) Endonuclease VIII-like 1, DNA bind

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_15838.1	9.997093137033517e-262
	Description: importin-beta domain-containing protein (1032 aa)
Oxytricha	Contig7467.0.g44	6.998907184881904e-97
	Description: Cse1
DictyBase	DDB_G0269860	2.0007467515522948e-59
	Description: DDB_G0269860 on chromosome: 1 position 3747132 to 3750705
SGD	YJR132W	6.0018235484001396e-36
	Description: NMD5 Karyopherin, a carrier protein involved in nuclear import of proteins; importin beta homolog
Stentor Coeruleus	SteCoe_11790	1.9287498479639178e-22
	Description: None
WormBase	WBGene00002079	0.000000000007000776811212012
	Description: locus:xpo-2 status:Partially_confirmed UniProt:Q965V4 protein_id:CCD67943.1
WormBase	WBGene00018037	0.000000000007000776811212012
	Description: locus:chtl-1 Choline transporter-like protein 1 status:Partially_confirmed UniProt:Q20026 protein_id:CCD62790.1

General Information

No Data fetched for General Information

Associated Literature

1. Ref:37024975: Nabeel-Shah S, Garg J, Ashraf K, Jeyapala R, Lee H, Petrova A, Burns JD, Pu S, Zhang Z, Greenblatt JF, Pearlman RE, Lambert JP, Fillingham J (2023) Multilevel interrogation of H3.3 reveals a primordial role in transcription regulation. Epigenetics & chromatin 16:10
2. Ref:34086947: Nabeel-Shah S, Garg J, Saettone A, Ashraf K, Lee H, Wahab S, Ahmed N, Fine J, Derynck J, Pu S, Ponce M, Marcon E, Zhang Z, Greenblatt JF, Pearlman RE, Lambert JP, Fillingham J (2021) Functional characterization of RebL1 highlights the evolutionary conservation of oncogenic activities of the RBBP4/7 orthologue in Tetrahymena thermophila. Nucleic acids research ( ):
3. Ref:24120531: Garg J, Lambert JP, Karsou A, Marquez S, Nabeel-Shah S, Bertucci V, Retnasothie DV, Radovani E, Pawson T, Gingras AC, Pearlman RE, Fillingham JS (2013) Conserved Asf1-importin ? physical interaction in growth and sexual development in the ciliate Tetrahymena thermophila. Journal of proteomics 94( ):311-26

Sequences

>TTHERM_00962200(coding)
ATGGTGGATCAACAAACTCTAATCTAAGTATTTTAAGGATTTTTTTCTAATGATCAACAA
ATGATTAATTAAGGATAGCAATTCATTCAACAAAATTGCTTGAATCCAAACTACTGTGTA
TCTTTAATGATTCTTGCTGACAGTAACAGTCAACAAGATAGTAACATTCGTCTTTCAGCT
ATTGCTAATTTAAAGAATACTGTAGAAAACTTCTGGCTTCCTAACAAAAACTACAACAAT
AATTAACTTTTAGAATAAGAAAAGGCAACACTTAGACAAAGTATTTTAGATGCTTTAATT
AGATCTATTAGTGATCAATAAATCTGTAAAGTTTACAAAAAGATTTTAAGCATAATCATT
AACTATGACTATCCTGCTGTTTGGCCAGATTTGTTGGAAACAGTAATCAATAGACTTGCT
CCTTCCCAAAACATGGAAGAAATTTAGGGCTGTCTATTTGCTCTCGAAAAATTATATTAA
AAATATGAATTTGAAATTGATAATCGTGCAATCATGGATCACATCATTAATAAGTCTATA
GTTATTTTGTAAAACCTTGCAGGCTAAATGATTTAAAATTACAGCGAATAAATTGCTCCT
CTGTTGAAAAGCATTCTTAAAATCTATTTCATGGCCATCGATATGCAATTCCCCATCATT
TTGGCTGAATAAAGCACATTCTAAAACTGGATGGTCATCTTCAAAATATTAATTGGATTC
AACATCCCTTAAAGCATCAACTAATCCTAAAACCCTGACAAAAACATTTACTGGAAAAAC
AGAAAGTGGTGCTTTAAAATCCTTATCAAAATTTTCCATAAATACTGCTTCAAGAATCCA
TAAGACAGAGTCATCCAACAAATTTCTTGCCTTTTCTTGTAAAAGTATGCAGTCCCATTC
TTTGAATCTGTGCTCGAAATTCTCTTTAATGAATATTACAAAGGCTAATACGTTTCAGAT
ATTGTCATTAATAACTGCATTCTTTTCATCTACTACTCCCTTGGCCATGATGAAACCTTC
AATGCTCTCCATCCTGTGCTTGAAAAGATTGTTTTAGATATTTGCATTCCTTTGCTTTCA
ACTACTCCAGAAGATTTTAACTTGTACAATCAAGATCCTGAAGATTACATTCGCAAGGAT
GAAGATAACTCTATTTTAGTGAATAAGAATACTTCAATCATGTTGATCAAGGAAGCTTGC
AAGATTACAAATCCTAATAATGAATCTTACTTGGAATATGTTTTATCTTTGATTGTGAAT
TGTCTTGACAAGGGAGTGAATCCTCGTAACAATTAAAATGTTACAATTGCACAGAAAGAG
GGTCTTTTCTAACTTATGGGAGTAATTAGAGAACAAGTCTATGAAGAGAAGAATCTTACT
GATCAATTAGAAAATATCATTTAAAGCTACATCGTTAAGGAACTTAATTCTGAGGCTAAC
ATCCTTAAGGCTCGTACTTGCTGGTTGCTTGGTAAATATGGAGGCCTTGACTTCAAAAAT
CCTTAAAACTTATCCACCATCATAGCTGGTATTTGCTAAAGAATGATTGACGGTGATTTG
GTTGTACGTGTAAAGGCTTCTATTGCTCTCTAGTACTACATTGACTAAGAGGGTGTTAAA
GACTTAGTCCGTCCAGGTTTGTCTGATATGCTTTCAATTTATATCAAGTTAATGCAATAA
ATAGATAATGAAAATTTAGTTTGCGCTTTAGAATGCATCGTAGAAAACTTCACTAATGAA
ATTACTCCTTTCGCTTATGATTTAGCTAATCATTTATCCATAGCTTTTTATAGATACAAA
GAAAAGGATTTAGATGAAGATCAAGCAGGTGAAGACGGTGAACTCCCAGCTGCAGGTTGT
CTTCAAGCTATCAACTAAATTTTAGAGTCACCTTTAGAAGTTGGAATTTATTCAAAAATG
GAAAACGATTTCTTACTTAAACTCATTATTGATTGCCTCACTGACAAAGATTTCCATTAC
TTAGAAGAAGGATTCAGTTTACTCAACACTCTTCTTTTCAAGTCTCCTTGCATTTCTAAT
AATCTTTGGATTTTCTATCCCTTTATTTGTTACGCAATTTTGGGATTCCCTCCTCAACTT
AACATCAACTCTCTTTCTTCAAATGATCACATCTAACTTTTCTCTATCCTCACCTAAAAC
ACAAGTTACTCCAGAAAGTAATGGGTTGAAGCTTTGGATAGTATGATTGGACCTATGAAG
AACTATTTCTAAAAGGGAAGAGATGTAATTTTAACTCAAAGCGATCCTTTCAACCAAAGC
TTAATCTAATTGCTATTTGAAATGGTTAAGATAACTTACTCTAACTCTAGTGAGTTTAAC
GAAGTTGATTAAATGTTGGCTACAAGCTTACTTATTGGCTTTGTTGAAAACATGTAAGAA
AATACAATTGACTAACTTCTTCCTGAAATTGTATCTTAATCTATCTAAAGAATGGGTAAT
ACCTAGTGCAAACCTCTTAAAGTTGTTAACATTGAAGTTGTTGCATTGTGTATCTACTAT
AATCCTTTACTCACTCTATAAATATTGGAAAGCAATGGATGGACTAGTGGTTTCTTTAGA
GAATACTTTGATTTACTTAACTACTTTAAAGCTGACTATGATAAGCAAAGAATGCTCGTA
GGTATAAGTTCTGTTTTCAAGTTAAACGAGAATCAATTACCTTCTACAATCCTCCAATCT
ATGCAAGGACTTATGCAATATCTTGTCAAGCTCTGCATGGAAATAGTGGAGCTCAGAGAG
AAAGGTGAAAAGGAAGATAACGAAGAACAAGCTGAAGTTGAAGTTCAATAATTCCATCAA
CAATTACAATAAATGTAATATAATCCTAATGATAATGCTAACGATGATGATGATGAAAAT
GATGAGGATTATGAAGAAAATGTTGAATTCAAAAGTAAAGTTATTCTCAGTTACACAAGT
CCTCTTGAATTATTTGATGAAATCCTTTACTTCGAAGGAGTTATGGCCAGCTGTATGGAA
AGAGACAACAATCTCTACCAAAAACTAATTGGATGTCTCAGTCCTCAAGAAACAAATCAA
CTCCAAAATTGTGTTAATTACGTTAAATCATAGTTATAGCAATAGTCTTGA

>TTHERM_00962200(gene)
ATGGTGGATCAACAAACTCTAATCTAAGTATTTTAAGGATTTTTTTCTAATGATCAACAA
ATGATTAATTAAGGATAGCAATTCATTCAACAAAATTGCTTGAATCCAAACTACTGTGTA
TCTTTAATGATTCTTGCTGACAGTAACAGTCAACAAGATAGTAACATTCGTCTTTCAGCT
ATTGCTAATTTAAAGAATACTGTAGAAAACTTCTGGCTTCCTAACAAAAACTACAACAAT
AATTAACTTTTAGAATAAGGTAGCACTTTTTGAAATTCGCATAAAAATAATGTTAACAAA
CAATTAATTAATTAATAAATCAAAAGAAAAGGCAACACTTAGACAAAGTATTTTAGATGC
TTTAATTAGATCTATTAGTGATCAATAAATCTGTAAAGTTTACAAAAAGATTTTAAGCAT
AATCATTAACTATGACTATCCTGCTGTTTGGCCAGATTTGTTGGAAACAGTAATCAATAG
ACTTGCTCCTTCCCAAAACATGGAAGAAATTTAGGGCTGTCTATTTGCTCTCGAAAAATT
ATATTAAAAATATGAATTTGAAATTGATAATCGTGCAATCATGGATCACATCATTAATAA
GTCTATAGTTATTTTGTAAAACCTTGCAGGCTAAATGATTTAAAATTACAGCGAATAAAT
TGCTCCTCTGTTGAAAAGCATTCTTAAAATCTATTTCATGGCCATCGATATGCAATTCCC
CATCATTTTGGCTGAATAAAGCACATTCTAAAACTGGATGGTCATCTTCAAAATATTAAT
TGGATTCAACATCCCTTAAAGCATCAACTAATCCTAAAACCCTGACAAAAACATTTACTG
GAAAAACAGAAAGTGGTGCTTTAAAATCCTTATCAAGTAATTAATTAGTTTGTTCTTTTA
AGTGTTATAACAAGATACCTAACTAATCTAATATATTTATTTAGTATAATCTATTTCCCT
AAAAATTAATAATCTTAACATTATTATAAAAATAAGAATTTTCCATAAATACTGCTTCAA
GAATCCATAAGACAGAGTCATCCAACAAATTTCTTGCCTTTTCTTGTAAAAGTATGCAGT
CCCATTCTTTGAATCTGTGCTCGAAATTCTCTTTAATGAATATTACAAAGGCTAATACGT
TTCAGATATTGTCATTAATAACTGCATTCTTTTCATCTACTACTCCCTTGGCCATGATGA
AACCTTCAATGCTCTCCATCGTAATAAATTCAAACATTTTTATCACAACCAGCAACATAA
ATATTTTTTATATAAACACCTTAATAAATAAATTAATTTTGCAAATGAAATAATGATTAA
ATAACTTTTAAACATCATGAATTATCAATTTATCAAAAATAAATATTTAAATTAATTTAT
TTTGAGCAAAAAAATATTTTTTAATTTTAATAAATAGCTGTGCTTGAAAAGATTGTTTTA
GATATTTGCATTCCTTTGCTTTCAACTACTCCAGAAGATTTTAACTTGTACAATCAAGAT
CCTGAAGATTACATTCGCAAGGATGAAGATAACTCTATTTTAGTGAATAAGGTAAAATTA
ATTTTAAATAATTGAATGAATTTATTAGAGTTAAAAAATGTTTACTAAAATAAATCATAA
AAAATATGAAGAATACTTCAATCATGTTGATCAAGGAAGCTTGCAAGATTACAAATCCTA
ATAATGAATCTTACTTGGAATATGTTTTATCTTTGATTGTGAATTGTCTTGACAAGGGAG
TGAATCCTCGTAACAATTAAAATGTTACAATTGCACAGAAAGAGGGTCTTTTCTAACTTA
TGGGAGTAATTAGAGAACAAGTATAAATTGTAATTTGCAATTAATACTGATTTAACTTAA
TTTTACTATTTGCAAAACAACAAAAGGTCTATGAAGAGAAGAATCTTACTGATCAATTAG
AAAATATCATTTAAAGCTACATCGTTAAGGAACTTAATTCTGAGGCTAACATCCTTAAGG
CTCGTACTTGCTGGTTGCTTGGTAAATATGGAGGCCTTGACTTCAAAAATCCTTAAAACT
TATCCACCATCATAGCTGTAAATATTAAACAATTTTAAAATTAACTTACTAATAAATAAT
ATTTAGGGTATTTGCTAAAGAATGATTGACGGTGATTTGGTTGTACGTGTAAAGGCTTCT
ATTGCTCTCTAGTACTACATTGACTAAGAGGGTGTTAAAGACTTAGTCCGTCCAGGTTTG
TCTGATATGCTTTCAATTTATATCAAGTTAATGCAATAAATAGATAATGAAAATTTAGTT
TGCGCTTTAGAATGCATCGTAGAAAACTTCACTAATGAAATTACTCCTTTCGCTTATGAT
TTAGCTAATCATTTATCCATAGCTTTTTATAGATACAAAGAAAAGGATTTAGATGAAGAT
CAAGCAGGTGAAGACGGTGAACTCCCAGCTGCAGGTTGTCTTCAAGTAATTTTTATTATT
TTAAAATGTTTTTATCTTGCTAAATAGTCTTAATATTAAATATTACTTAGGCTATCAACT
AAATTTTAGAGTCACCTTTAGAAGTTGGAATTTATTCAAAAATGGAAAACGATTTCTTAC
TTAAACTCATTATTGATTGCCTCACTGACAAAGATTTCCATTACTTAGAAGAAGGATTCA
GTTTACTCAACACTCTTCTTTTCAAGTCTCCTTGCATTTCTAATAATCTTTGGATTTTCT
ATCCCTTTATTTGTTACGCAATTTTGGGATTCCCTCCTCAACTTAACATCAACTCTCTTT
CTTCAAATGATCACATCTAACTTTTCTCTATCCTCACCTAAAACACAAGTTACTCCAGAA
GTAATTTATTTCATTTTTTATCTTAAAAACTTCCAAAATAAATAATTTCTTAGCATTTAT
TTTTTAATTTCAACATAAAGAAAAACAAAAAAACATTTCAGAATTCTTTTTATTTTAAAT
ATTTACTAAAAAAATATTTTAATTTTTAAAAATAAATAGAGTAATGGGTTGAAGCTTTGG
ATAGTATGATTGGACCTATGAAGAACTATTTCTAAAAGGGAAGAGATGTAATTTTAACTC
AAAGCGATCCTTTCAACCAAAGCTTAATCTAATTGCTATTTGAAATGGTTAAGATAACTT
ACTCTAACTCTAGTGAGTTTAACGAAGTTGATTAAATGTTGGCTACAAGCTTACTTATTG
GCTTTGTTGAAAACATGTAAGAAAATACAATTGACTAACTTCTTCCTGAAATTGTATCTT
AATCTATCTAAAGAATGGGTAATACCTAGTGCAAACCTCTTAAAGTTGTTAACATTGAAG
TTGTTGCATTGTGTATCTACTATAATCCTTTACTCACTCTATAAATATTGGAAAGCAATG
GATGGACTAGTGGTTTCTTTAGAGAATACTTTGATTTACTTAACTACTTTAAAGCTGACT
ATGATAAGCAAAGAATGCTCGTAGGTATAAGTTCTGTTTTCAAGTTAAACGAGAATCAAT
TACCTTCTACAATCCTCCAATCTATGCAAGGACTTATGCAATATCTTGTCAAGCTCTGCA
TGGAAATAGTGGAGCTCAGAGAGAAAGGTGAAAAGGAAGATAACGAAGAACAAGCTGAAG
TTGAAGTTCAATAATTCCATCAACAATTACAATAAATGTAATATAATCCTAATGATAATG
CTAACGATGATGATGATGAAAATGATGAGGATTATGAAGAAAATGTTGAATTCAAAAGTA
AAGTTATTCTCAGTTACACAAGTCCTCTTGAATTATTTGATGAAATCCTTTACTTCGAAG
GAGTTATGGCCAGCTGTATGGAAAGAGACAACAATCTCTACCAAAAACTAATTGGATGTC
TCAGTCCTCAAGAAACAAATCAACTCCAAAATTGTGTTAATTACGTTAAATCATAGTTAT
AGCAATAGTCTTGA

>TTHERM_00962200(protein)
MVDQQTLIQVFQGFFSNDQQMINQGQQFIQQNCLNPNYCVSLMILADSNSQQDSNIRLSA
IANLKNTVENFWLPNKNYNNNQLLEQEKATLRQSILDALIRSISDQQICKVYKKILSIII
NYDYPAVWPDLLETVINRLAPSQNMEEIQGCLFALEKLYQKYEFEIDNRAIMDHIINKSI
VILQNLAGQMIQNYSEQIAPLLKSILKIYFMAIDMQFPIILAEQSTFQNWMVIFKILIGF
NIPQSINQSQNPDKNIYWKNRKWCFKILIKIFHKYCFKNPQDRVIQQISCLFLQKYAVPF
FESVLEILFNEYYKGQYVSDIVINNCILFIYYSLGHDETFNALHPVLEKIVLDICIPLLS
TTPEDFNLYNQDPEDYIRKDEDNSILVNKNTSIMLIKEACKITNPNNESYLEYVLSLIVN
CLDKGVNPRNNQNVTIAQKEGLFQLMGVIREQVYEEKNLTDQLENIIQSYIVKELNSEAN
ILKARTCWLLGKYGGLDFKNPQNLSTIIAGICQRMIDGDLVVRVKASIALQYYIDQEGVK
DLVRPGLSDMLSIYIKLMQQIDNENLVCALECIVENFTNEITPFAYDLANHLSIAFYRYK
EKDLDEDQAGEDGELPAAGCLQAINQILESPLEVGIYSKMENDFLLKLIIDCLTDKDFHY
LEEGFSLLNTLLFKSPCISNNLWIFYPFICYAILGFPPQLNINSLSSNDHIQLFSILTQN
TSYSRKQWVEALDSMIGPMKNYFQKGRDVILTQSDPFNQSLIQLLFEMVKITYSNSSEFN
EVDQMLATSLLIGFVENMQENTIDQLLPEIVSQSIQRMGNTQCKPLKVVNIEVVALCIYY
NPLLTLQILESNGWTSGFFREYFDLLNYFKADYDKQRMLVGISSVFKLNENQLPSTILQS
MQGLMQYLVKLCMEIVELREKGEKEDNEEQAEVEVQQFHQQLQQMQYNPNDNANDDDDEN
DEDYEENVEFKSKVILSYTSPLELFDEILYFEGVMASCMERDNNLYQKLIGCLSPQETNQ
LQNCVNYVKSQLQQQS