Identifiers and Description

Gene Model Identifier

TTHERM_01014460

Standard Name

CST1 (Calcium-dependent Serine/Threonine kinase 1)

Aliases

PreTt04576 | 197.m00050 | 3748.m00287

Description

CST1 kinase domain protein; Protein kinase domain containing protein; involved in programmed nuclear death of macronucleus and reabsorption by autophagosome

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Cellular Component

• cytoplasm (IDA) | GO:0005737

Molecular Function

• ATP binding (IEA) | GO:0005524
• protein kinase activity (IEA) | GO:0004672
• protein tyrosine kinase activity (IEA) | GO:0004713

Biological Process

• programmed cell death (IDA) | GO:0012501
• protein phosphorylation (IEA) | GO:0006468

Domains

No Data fetched for Domains

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_20204.1	9.997093137033517e-262
	Description: hypothetical protein (1196 aa)
Oxytricha	Contig10141.0.g45	1.0002323021920326e-132
	Description: Protein kinase domain
WormBase	WBGene00000553	9.998819815181669e-76
	Description: locus:cmk-1 Calcium/calmodulin-dependent protein kinase type 1 status:Confirmed UniProt:Q9TXJ0 protein_id:CCD71865.1
DictyBase	DDB_G0279925	2.0004485223439647e-69
	Description: mlkA on chromosome: 3 position 2752719 to 2754560
SGD	YFR014C	1.0004249259458435e-52
	Description: CMK1 Calmodulin-dependent protein kinase; may play a role in stress response, many CA++/calmodulan dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to Cmk2p and mammalian Cam Kinase II
Stentor Coeruleus	SteCoe_18176	3.093350011308561e-50
	Description: None

General Information

No Data fetched for General Information

Associated Literature

1. Ref:16933976: Eisen JA, Coyne RS, Wu M, Wu D, Thiagarajan M, Wortman JR, Badger JH, Ren Q, Amedeo P, Jones KM, Tallon LJ, Delcher AL, Salzberg SL, Silva JC, Haas BJ, Majoros WH, Farzad M, Carlton JM, Smith RK, Garg J, Pearlman RE, Karrer KM, Sun L, Manning G, Elde NC, Turkewitz AP, Asai DJ, Wilkes DE, Wang Y, Cai H, Collins K, Stewart BA, Lee SR, Wilamowska K, Weinberg Z, Ruzzo WL, Wloga D, Gaertig J, Frankel J, Tsao CC, Gorovsky MA, Keeling PJ, Waller RF, Patron NJ, Cherry JM, Stover NA,

Sequences

>TTHERM_01014460(coding)
ATGAATCCTCTTATGAGCCCCTGTATGATTGAAAAGCAATGGCTTATTAAATCTAAAATG
GGAAATATTGAAGATGACTATGATTTTGACTAAAAGAAAGATAATTTAGGTGAAGGATCA
TATGGTGTTGTATATAAAGCTACCATGAAATCAACTGGATAAATTAGGGCTGTGAAAGTT
ATTAATAAAAGCAGAGTAAAACATTAAGAGCGCTTAAAAAATGAAATTGAAATTATGTCA
ACACTGGATCATCCTAACATTATCAGATTATATGAGACATATGAAGATCAGAAAAATATT
TACTTGGTTATAGAATACTGTGAAGGAGGAGAACTTTTTGACAGAATAGCAGAAAGAGGC
TACTATACAGAGTAAGATGCTGTTGCACTATTTAGATAAATTATGAGTGCAATCAATTAT
TGTCACTCTCGAAAAATATGTCATAGAGACTTAAAACCTGAAAATTTCTTGTTTTGCACT
AAAGATGACAACTCAATAATTAAGGTAATTGATTTTGGTCTTTCTAAAACATATGGGCAA
GTTTTAGATTCTCCTCTCAAAAAGAAGCCTTTAGAATTAACTCAAGTACAAAGCGGCGTT
ATGAAAACTAGAGCAGGAACACCATATTATATTGCTCCAGAAGTACTTGATGGTAAATAT
GATGAAAAATGTGATATCTGGTCAGCTGGTGTTACTTTGTATATTATTCTTTGCGGCTAT
CCCCCATTTTATGGAGAAACTGATAAGGAAATTCTACAAGCTGTAAAAAAAGGAGAATAT
GAATATGAAGGCGATGAATGGGATATTGTGAGCGATGAATGCAAAAACTTAATCAAAAAA
ATGCTTAGTAAGCCAGAGCTAAGATTCAGTTCAGAAATGGTTATGGCCTCCAAATGGATA
TAAAAGTATAGTCCTCCAATTAAAAATGATGCCAAAATTCCATTTTAGAAGATTAAATTA
TGGAATACTTATCCCAAGCTCAAAAAGCTAGCCCTAAGCTATATTGCTTCATAAATGAGC
ATGTTTTAGATATAACCCATAGCTAAACAATTTATTTTGATTGATAAAGACTTTGATGGC
TGCTTGACTTTATAGGAGCTCATAAATGGAACATAAGACTCTCAAAACCCAGAAAATTAA
GAAATTATTAAGCAAACATTTAAATCTTTTGTTTCATATTTACCAAATAAAATAGCATTT
ACAGATTTTGTAGCTCTCGTTATGGATTCCAGCATTTATTTGAAGGATAATATAATCCGC
CAAGCCTTTAAAATTTTTGATAAAAATAACATTGGTAAAATATCTCCAAACCATCTTAAC
GAGCTCTTTTTGGATAATGCATATTACGCAAAGAAAAAAATTGATTATTGGGTTGATATG
GTAAAATGCTGTGACTTCAAGAATGATGGAGTGATTGATTACGAAGAATTTAGCAAAATG
ATCTATGAAAATAGCGAATAAATGTAAATAAGTGCTTGA

>TTHERM_01014460(gene)
ATGAATCCTCTTATGAGCCCCTGTATGATTGAAAAGCAATGGCTTATTAAATCTAAAATG
GGAAATATTGAAGATGACTATGATTTTGACTAAAAGAAAGATGTAATTTAGCATTATTTA
ACATTTTTTTATTAGCATATAAAAATCATAATTTGGTCAGTTTATTAATTACTCCCTTAA
AATATATTTTTTTTATATAAATAGAATTTAGGTGAAGGATCATATGGTGTTGTATATAAA
GCTACCATGAAATCAACTGGATAAATTAGGGCTGTGAAAGTTATTAATAAAAGCAGAGTA
AAACATTAAGAGCGCTTAAAAAATGAAATTGAAATTATGTCAACACTGGTAATCTCATTT
ACTTCTACTTTTTAATTGAGAGCGCGTTAAAAATAAAAACATTTTTACTGAATAGGATCA
TCCTAACATTATCAGATTATATGAGACATATGAAGATCAGAAAAATATTTACTTGGTTAT
AGAGTAATTTTTCTATTAAACGATTAGTTAGCAAAATTATTTCCATTAAATGCAAATATT
TCTTTATTCTATAGTTTTATTTCATTTATCAATATATAAATAGATACTGTGAAGGAGGAG
AACTTTTTGACAGAATAGCAGAAAGAGGCTACTATACAGAGTAAGATGCTGTTGCACTAT
TTAGATAAATTATGAGTGCAATCAATTATTGTCACTCTCGAAAAATATGTCATAGAGACT
TAAAACCTGAAAATTTCTTGTTTTGCACTAAAGATGACAACTCAATAATTAAGGTAATTT
AGTAAAAATTTATGAAGTGAAGCAAGTTTTTAAATATTTATCTTGAAACTATTATTTTAT
TTAAAAATATTTAAAATTTTTAAAAGAGTTTTTTTCAATAAAGTTATTCTTTATGAAATT
AAATTATTTTTTTCCATCAAAAAATTCAGAGAAAAAAAAACTAATCATTTTTATGAGATT
TTGTTTATGAATAAATTATCTTACTATTTAATTAATTAGTTTATTTTTATTTATTTAATT
GATTGATTGATGATAATTTAATTTCTTTTTATATTTTAATCAAAGGTAATTGATTTTGGT
CTTTCTAAAACATATGGGCAAGTTTTAGATTCTCCTCTCAAAAAGAAGCCTTTAGAATTA
ACTCAAGTACAAAGCGGCGTTATGAAAACTAGAGCAGGAACAGTAAAATTATAATTTTTT
ATTAAAATAAATTAATTTAAATATAAAATATTTTATCTTAAACAAATTTAAAATTCATAA
AAGCCATATTATATTGCTCCAGAAGTACTTGATGGTAAATATGATGAAAAATGTGATATC
TGGTCAGCTGGTGTTACTTTGTATATTATTCTTTGCGGCTATCCCCCATTTTATGGAGAA
ACTGATAAGGAAATTCTACAAGCTGTAAAAAAAGGAGAATATGAATATGAAGGTATCTAA
TTAAACTTTTCTTTACATAAGTTAATTATCAAAAAAAAAAATAGGCGATGAATGGGATAT
TGTGAGCGATGAATGCAAAAACTTAATCAAAAAAATGCTTAGTAAGCCAGAGCTAAGATT
CAGTTCAGAAATGGTTATGGCCTCCAAATGGATATAAAAGTATAGTCCTCCAATTAAAAA
TGATGCCAAAATTCCATTTTAGAAGATTAAATTATGGAATACTTATCCCAAGCTCAAAAA
GCTAGCCCTAAGCTATATTGCTTCATAAATGAGCATGTTTTAGATATAACCCATAGCTAA
ACAATTTATTTTGATTGATAAAGACTTTGATGGCTGCTTGACTTTATAGGAGCTCATAAA
TGGAACATAAGACTCTCAAAACCCAGAAAATTAAGAAATTATTAAGCAAACATTTAAATC
TTTTGTTTCATATTTACCAAATAAAATAGCATTTACAGGTAATATTTTAATTTAGAAAAA
AAACTGATCAATTTTCAAATTTTTAGAAACCAAAAATTTTTTTTCTTAAAACATCCCATT
TTAATTTTTAAAAATTTAAAAATGCAAAAAATATTTAAAAAATATAAAATTTCACATATT
TAAATTAATCAATAATGAAATAATTAAAATAGATTTTGTAGCTCTCGTTATGGATTCCAG
CATTTATTTGAAGGATAATATAATCCGCCAAGCCTTTAAAATTTTTGATAAAAATAACAT
TGGTAAAATATCTCCAAACCATCTTAACGAGCTCTTTTTGGGTAAAATACTGTTTTTTTT
TAAAGGATTTATTAAGTTAATTTATTATTTTAAAAGATAATGCATATTACGCAAAGAAAA
AAATTGATTATTGGGTTGATATGGTAAAATGCTGTGACTTCAAGAATGATGGAGTGGTAA
ATTATTTCATTAAATAAGCAAATCAATTTTATTTAAAAATAATTTAAATTAAATTATCTT
TGAATTATAAAAAATAATTTTATTTTTTTAAATTTACAAATAAATTGTGTTTTAAAAATA
GATTGATTACGAAGAATTTAGCAAAATGATCTATGAAAATAGCGAATAAATGTAAATAAG
TGCTTGA

>TTHERM_01014460(protein)
MNPLMSPCMIEKQWLIKSKMGNIEDDYDFDQKKDNLGEGSYGVVYKATMKSTGQIRAVKV
INKSRVKHQERLKNEIEIMSTLDHPNIIRLYETYEDQKNIYLVIEYCEGGELFDRIAERG
YYTEQDAVALFRQIMSAINYCHSRKICHRDLKPENFLFCTKDDNSIIKVIDFGLSKTYGQ
VLDSPLKKKPLELTQVQSGVMKTRAGTPYYIAPEVLDGKYDEKCDIWSAGVTLYIILCGY
PPFYGETDKEILQAVKKGEYEYEGDEWDIVSDECKNLIKKMLSKPELRFSSEMVMASKWI
QKYSPPIKNDAKIPFQKIKLWNTYPKLKKLALSYIASQMSMFQIQPIAKQFILIDKDFDG
CLTLQELINGTQDSQNPENQEIIKQTFKSFVSYLPNKIAFTDFVALVMDSSIYLKDNIIR
QAFKIFDKNNIGKISPNHLNELFLDNAYYAKKKIDYWVDMVKCCDFKNDGVIDYEEFSKM
IYENSEQMQISA