Identifiers and Description

Gene Model Identifier

TTHERM_01018450

Standard Name

THD12 (Tetrahymena Histone Deacetylase 12)

Aliases

PreTt27762 | 199.m00055

Description

THD12 SIR2 family transcriptional regulator; Sir2-like histone deacetylase; suppresses DNA transcription by deacetylation of histones; homolog of Mus muscalus SIRT6; NAD-dependent sirtuin protein deacylases

Genome Browser (Macronucleus)

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Genome Browser (Micronucleus)

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External Links

Gene Ontology Annotations

No Data fetched for Gene Ontology Annotations

Domains

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

No Data fetched for Homologs

General Information

No Data fetched for General Information

Associated Literature

  1. Ref:18178773: Smith JJ, Torigoe SE, Maxson J, Fish LC, Wiley EA (2008) A class II histone deacetylase acts on newly synthesized histones in Tetrahymena. Eukaryotic cell 7(3):471-82

Sequences 

>TTHERM_01018450(coding)
ATGCATTTTTCTATCAAGATTTTAATAGAACTTGATAGCGCATAATTTCTAAGCCTCTTT
TCTATATAATCTGCCAAAATCTTTAAACAGATTTTACAAAGCAGGTCAATTTTATAATTA
AATAACTTCAAATAAAAAAAATAAGAACTAAATAAATAAATTAGAATTAAATAACGAAAT
TATCTTTCAAAGTAAAAATATCAAATTAAAATGGATACTGCACACAAAACAGAAGATGAA
AAAAAGGAATACTTCGATGCTCCTGATGTTTTAGAATAAAAGGTTACTCTTTTAGCTGAA
ATGATTAAAACTTCAAAGCACTTTGTAGCTTTCACAGGAGCAGGAATTTCTACTTCTACA
GGAATTCCTGATTTTAGAAGTGGAATTAACACTGTTCTTCCTACTGGACCAGGAGCTTGG
GAGAAATTAGCCTAAAAAGTTGATAATAAGCATAAAAATATCAAGACTAGCATGTTGAAA
GCTATTCCTTCACCCACACATATGGCTTTGGTTTAGTTACAAAAAATAGGTTATTTGAAA
TTCCTTATTAGCTAAAATGTAGACGGATTGCACAGAAGAAGTGGTTTCTCACCCTAACAC
TTAGCTGAATTGCATGGCAATACAAATCTTGAAAAATGTAAAAAATGTGGCAAAGAATAC
TTGAGAGATTTTAGAGTTAGAAATGCATAGAAAGTTCATGATCACAAAACAGGTAGAAAG
TGCAGCGATTAAAAATGCAAAGGAGATCTTTATGACTCTATTATAAATTTTGGTGAAAAT
TTACCTGAAAAAGATTTAAATGAAGGATTTGCTTAATCAAAAAAATCTGATTTGCATTTG
GTTTTAGGAAGTAGTTTAAGAGTAACACCTGCTGCAGACATGCCTGCCACCACTGCAGAA
AAAGGTCAAAAATTAGTTATAATAAACTTGCAAAAAACTCCTTTAGACTCAGTAGCTACT
CTCAGAATAAATGCTATGTGTGATGATGTTATGAAAATGGTTATGAAAAAACTTGGATTA
GATATACCAGAATTCACTCTTGAAAGAAGAGTTGTCTTAGAAAAAACAGGTATGAATGCC
TTAACAGTTTCAAGCTAAGACTCGGACGATTCCCCCTATGATTTGTTTAAATAAATTAAA
GTAGATTACGGCAAAATACATCCTGAATAAACTTTACTTAAGGCTCCATTCAATATCATA
CCAAAAAATAAAACATTCTCTCTAAATTTAAGCTTTTATGGACACTATGGCGAGCAAGAT
TTTAACTTAAATATCGATATGGCTGCTCTCTCCATTAATAAAAAAGTGAAATATTTAATA
CAATATTCACCAAAAGAATAAAAATGGATTAGTTGCAAAGAAATATGA



>TTHERM_01018450(gene)
TTTTATATGCATTTTTCTATCAAGATTTTAATAGAACTTGATAGCGCATAATTTCTAAGC
CTCTTTTCTATATAATCTGCCAAAATCTTTAAACAGATTTTACAAAGCAGGTCAATTTTA
TAATTAAATAACTTCAAATAAAAAAAATAAGAACTAAATAAATAAATTAGAATTAAATAA
CGAAATTATCTTTCAAAGTAAAAATATCAAATTAAAATGGATACTGCACACAAAACAGAA
GATGAAAAAAAGGAATACTTCGATGCTCCTGATGTTTTAGAATAAAAGGTTACTCTTTTA
GCTGAAATGATTAAAACTTCAAAGCACTTTGTAGCTTTCACAGGAGCAGGAATTTCTACT
TCTACAGGAATTCCTGATTTTAGAAGTGGAATTAACACTGTTCTTCCTACTGGACCAGGA
GCTTGGGAGAAATTAGCCTAAAAAGTTGATAATAAGCATAAAAATATCAAGACTAGCATG
TTGAAAGCTATTCCTTCACCCACACATATGGCTTTGGTTTAGTTACAAAAAATAGGTTAT
TTGAAATTCCTTATTAGCTAAAATGTAGACGGATTGCACAGAAGAAGTGGTTTCTCACCC
TAACACTTAGCTGAATTGCATGGCAATACAAATCTTGAAAAATGTAAAAAATGTGGCAAA
GAATACTTGAGAGATTTTAGAGTTAGAAATGCATAGAAAGTTCATGATCACAAAACAGGT
AGAAAGTGCAGCGATTAAAAATGCAAAGGAGATCTTTATGACTCTATTATAAATTTTGGT
GAAAATTTACCTGAAAAAGATTTAAATGAAGGATTTGCTTAATCAAAAAAATCTGATTTG
CATTTGGTTTTAGGAAGTAGTTTAAGAGTAACACCTGCTGCAGACATGCCTGCCACCACT
GCAGAAAAAGGTCAAAAATTAGTTATAATAAACTTGCAAAAAACTCCTTTAGACTCAGTA
GCTACTCTCAGAATAAATGCTATGTGTGATGATGTTATGAAAATGGTTATGAAAAAACTT
GGATTAGATATACCAGAATTCACTCTTGAAAGAAGAGTTGTCTTAGAAAAAACAGGTATG
AATGCCTTAACAGTTTCAAGCTAAGACTCGGACGATTCCCCCTATGATTTGTTTAAATAA
ATTAAAGTAGATTACGGCAAAATACATCCTGAATAAACTTTACTTAAGGCTCCATTCAAT
ATCATACCAAAAAATAAAACATTCTCTCTAAATTTAAGCTTTTATGGACACTATGGCGAG
CAAGATTTTAACTTAAATATCGATATGGCTGCTCTCTCCATTAATAAAAAAGTGAAATAT
TTAATACAATATTCACCAAAAGAATAAAAATGGATTAGTTGCAAAGAAATATGAAAATAA
AAAATATATAAAAAATGAATTAATTAATTAATTAAAATACTGCTTTATATTACATAAGTA
TTAATTACTATTATATAAAACCACTTTTCTTATAATGATTTAATT



>TTHERM_01018450(protein)
MHFSIKILIELDSAQFLSLFSIQSAKIFKQILQSRSILQLNNFKQKKQELNKQIRIKQRN
YLSKQKYQIKMDTAHKTEDEKKEYFDAPDVLEQKVTLLAEMIKTSKHFVAFTGAGISTST
GIPDFRSGINTVLPTGPGAWEKLAQKVDNKHKNIKTSMLKAIPSPTHMALVQLQKIGYLK
FLISQNVDGLHRRSGFSPQHLAELHGNTNLEKCKKCGKEYLRDFRVRNAQKVHDHKTGRK
CSDQKCKGDLYDSIINFGENLPEKDLNEGFAQSKKSDLHLVLGSSLRVTPAADMPATTAE
KGQKLVIINLQKTPLDSVATLRINAMCDDVMKMVMKKLGLDIPEFTLERRVVLEKTGMNA
LTVSSQDSDDSPYDLFKQIKVDYGKIHPEQTLLKAPFNIIPKNKTFSLNLSFYGHYGEQD
FNLNIDMAALSINKKVKYLIQYSPKEQKWISCKEI