Identifiers and Description

Gene Model Identifier

TTHERM_01029960

Standard Name

MDH4 (malate dehydrogenase 4)

Aliases

PreTt10826 | 204.m00055

Description

MDH4 cytoplasmic and cytosolic malate dehydrogenase family protein; malate dehydrogenase family protein

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Molecular Function

• oxidoreductase activity (IEA) | GO:0016491

Biological Process

• obsolete oxidation-reduction process (IEA) | GO:0055114

Domains

• ( PF00056 ) lactate/malate dehydrogenase, NAD binding domain
• ( PF02866 ) lactate/malate dehydrogenase, alpha/beta C-terminal domain
• ( TIGR01756 ) lactate dehydrogenase
• ( TIGR01757 ) malate dehydrogenase, NADP-dependent
• ( TIGR01758 ) malate dehydrogenase, NAD-dependent
• ( TIGR01759 ) malate dehydrogenase
• ( TIGR01763 ) malate dehydrogenase, NAD-dependent
• ( TIGR01772 ) malate dehydrogenase, NAD-dependent

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_10494.1	9.997093137033517e-262
	Description: malate dehydrogenase (337 aa)
DictyBase	DDB_G0280255	6.996525358388811e-93
	Description: mdhC on chromosome: 3 position 3171359 to 3172577
Oxytricha	Contig22377.0.g62	1.0002434920975502e-91
	Description: lactate/malate dehydrogenase, alpha/beta C-terminal domain
WormBase	WBGene00018491	4.999773105566236e-81
	Description: locus:mdh-1 Malate dehydrogenase status:Confirmed UniProt:Q9UAV5 protein_id:CCD71316.1
Stentor Coeruleus	SteCoe_18880	2.506567475899953e-46
	Description: None
SGD	YKL085W	0.0000000000002999981760818895
	Description: MDH1 Mitochondrial malate dehydrogenase, catalyzes interconversion of malate and oxaloacetate; involved in the tricarboxylic acid (TCA) cycle; phosphorylated

General Information

No Data fetched for General Information

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_01029960(coding)
ATGATAAAAGAATACTTTTTTTAGAATTATTATTTATTTTAATTTATTCCAAAAAAAACA
TAAATAAATGGTATGATTTAAAAATAATTATTTTTGGTAGAATATGTTAGATAGGAAGGA
TATAAAATTTTTATTATTTTATATGCAAATATGCAACCATCATTTTTCTTTAGAAATTAA
GATAGCATAAATGTTAAGCACTTTAGACATATAAAGCATGCATACGCATATTTACATACA
GGATGTGTCTATTTATAATCCGTCAAAGGATTAGCACCAACAAAGATAGAACGAGTCATT
TAGGTTTAACGAGAATCATATTATGATTAAGTCATCTATCATGATCCTAATTAAAAATCA
AATAAAAAAGTGATCAATTAAATTAGTAAAGATAAAAGAAAAAATAAATAAACAAATATC
AGGATTTACTAAAAAATTAAAAAGGAAAGAAAATTAGTTTAACTTTTACTTTTTGATAAT
TTAATTTCTGGTACTTAGTTATTTTTAGAAATAAAAGAAAAAAATAATTAATTAATTTGC
AAAAACATTTAAAAGAAATTAAAAGTATTTATCATTTTTAAAAAAAATATAAAACATATT
TTAGAAGTTATGGAGAATAAAGCAGTTATTAATGTTTGTATTACAGGCGCTGCTGGTAAT
ATTGCATACGCCTTGTATTCTATATTGTGCACTGGCCAAATATTTGGGTCTAATCAAAAA
ATGAACTTAAAGCTTTTAGATATTGAATCTCAAGCAAAGGGTCTTTAAGGAGTTGCATTA
GAATTAGAAGATTGCGCCTATGCCCTCGTTAATTCGATAGAGTACGGTTTTGACCCCGAA
GTACTTTTCAAAGATATGGATGTTGGCATTTTCCTCGGAGGGTAATCAAGAAGACCTGGT
ATGGAAAGAGTTGATTTACTTTAAGTAAATAACAGAATTTTCAAGATCTAGGGTAAAGCT
TTGAATAAAGTAGCTAAGCCAAGCACTAAGATTCTAGTAATCGCAAATCCAGTAAACACA
AATTGCTTAACTTTGATTCAAAATTGTCCTAACATTCCTAAAGAAAATTTCACTTGCTTG
ACAAGACTTGACCACAATAGAGCAATAGCATAATTAGCAATCAAAGCAAAAGTACCTGTT
ACCGAAGTTAAAAATGTTATTCTATGGGGTAACCATAGTTTAACTATGTATCCAGATCAC
AATCATGCACACATTGAAGGTCAACCAGCAGTAGATATATATGAAGAGGAATGGATTAAG
AATACTTTCATTCCTAAAGTTTAAAAAAGGGGAGGAGAAGTTCTAAATTTGAGATAGAAC
TCCTCAGTTATGAGTGCTGCAATTGCTATTCGTGACCACTTAGTTAATTGGATTTATGGA
ACTCCTGAAGGATAGTTCGTATCTATGGGTGTTTACACTGACGGAAGCTTCTATGATATT
CCCGCAGATTTTGTTTTCTCAGTTCCAGTTAAGTGCAAAGACTTTAAATACGAAGTTGTT
AAGGATTTGACTATTAGCTAGTTTTCAAGATAAAAAATTAACATCAGTTTGAGAGAATTG
TAAGATGAGAAAGAAGAAGCTAACTGCTACGACGATGATGCTGAAGACGAATCTGAAGAG
TGA

>TTHERM_01029960(gene)
ATGATAAAAGAATACTTTTTTTAGAATTATTATTTATTTTAATTTATTCCAAAAAAAACA
TAAATAAATGGTATGATTTAAAAATAATTATTTTTGGTAGAATATGTTAGATAGGAAGGA
TATAAAATTTTTATTATTTTATATGCAAATATGCAACCATCATTTTTCTTTAGAAATTAA
GATAGCATAAATGTTAAGCACTTTAGACATATAAAGCATGCATACGCATATTTACATACA
GGATGTGTCTATTTATAATCCGTCAAAGGATTAGCACCAACAAAGATAGAACGAGTCATT
TAGGTTTAACGAGAATCATATTATGATTAAGTCATCTATCATGATCCTAATTAAAAATCA
AATAAAAAAGTGATCAATTAAATTAGTAAAGATAAAAGAAAAAATAAATAAACAAATATC
AGGATTTACTAAAAAATTAAAAAGGAAAGAAAATTAGTTTAACTTTTACTTTTTGATAAT
TTAATTTCTGGTACTTAGTTATTTTTAGAAATAAAAGAAAAAAATAATTAATTAATTTGC
AAAAACATTTAAAAGAAATTAAAAGTATTTATCATTTTTAAAAAAAATATAAAACATATT
TTAGAAGTTATGGAGAATAAAGCAGTTATTAATGTTTGTATTACAGGCGCTGCTGGTAAT
ATTGCATACGCCTTGTATTCTATATTGTGCACTGGCCAAATATTTGGGTCTAATCAAAAA
ATGAACTTAAAGCTTTTAGATATTGAATCTCAAGCAAAGGGTCTTTAAGGAGTTGCATTA
GAATTAGAAGATTGCGCCTATGCCCTCGTTAATTCGATAGAGTACGGTTTTGACCCCGAA
GTACTTTTCAAAGATATGGATGTTGGCATTTTCCTCGGAGGGTAATCAAGAAGACCTGGT
ATGGAAAGAGTTGATTTACTTTAAGTAAATAACAGAATTTTCAAGATCTAGGGTAAAGCT
TTGAATAAAGTAGCTAAGCCAAGCACTAAGATTCTAGTAATCGCAAATCCAGTAAGAAAA
AAAATATATTTTTATAGAAAACTTAGATAATTACCAACTTAATTATGCACGTTAGTTAAA
GAATCAGATTGGTTAGTTTAAGTATCAATTTGAAATGGTAGAGATAAAAATTTGATTGAT
TTGCTAATGTGCTGATTGACTAATAAGCAGTCAATCTATTTTGTTTATGACAAAATTGAA
ATACTTTTATAAGTTTTGATAATCTATTACAATTATGAATATCAACATTATTAATAAGCA
TTCAATTAATGTAAAAATAATCTTATTATCTGTTTTATAATAAAAAGGTAAACACAAATT
GCTTAACTTTGATTCAAAATTGTCCTAACATTCCTAAAGAAAATTTCACTTGCTTGACAA
GACTTGACCACAATAGAGCAATAGCATAATTAGCAATCAAAGCAAAAGTACCTGTTACCG
AAGTTAAAAATGTTATTCTATGGGGTAATTAATTTAAATGTCAAAAATCAAGAGGAATTG
GCATTCTATTTAAAGAATTTTAATATCATTTTAATAATTTACATAGGTAACCATAGTTTA
ACTATGTATCCAGATCACAATCATGCACACATTGAAGGTCAACCAGCAGTAGATATATAT
GAAGAGGAATGGATTAAGAATACTTTCATTCCTAAAGTTTAAAAAAGGGGAGGAGAAGTT
CTAAATTTGAGATAGAACTCCTCAGTTATGAGTGCTGCAATTGCTATTCGTGACCACTTA
GTTAATTGGATTTATGGAACTCCTGAAGGATAGTTCGTATCTATGGGTGTTTACACTGAC
GGAAGCTTCTATGATATTCCCGCAGATTTTGTTTTCTCAGTTCCAGTTAAGTGCAAAGAC
TTTAAATACGAAGTTGTTAAGGATTTGACTATTAGCTAGTTTTCAAGATAAAAAATTAAC
ATCAGTTTGAGAGAATTGTAAGATGAGAAAGAAGAAGCTAACTGCTACGACGATGATGCT
GAAGACGAATCTGAAGAGTGA

>TTHERM_01029960(protein)
MIKEYFFQNYYLFQFIPKKTQINGMIQKQLFLVEYVRQEGYKIFIILYANMQPSFFFRNQ
DSINVKHFRHIKHAYAYLHTGCVYLQSVKGLAPTKIERVIQVQRESYYDQVIYHDPNQKS
NKKVINQISKDKRKNKQTNIRIYQKIKKERKLVQLLLFDNLISGTQLFLEIKEKNNQLIC
KNIQKKLKVFIIFKKNIKHILEVMENKAVINVCITGAAGNIAYALYSILCTGQIFGSNQK
MNLKLLDIESQAKGLQGVALELEDCAYALVNSIEYGFDPEVLFKDMDVGIFLGGQSRRPG
MERVDLLQVNNRIFKIQGKALNKVAKPSTKILVIANPVNTNCLTLIQNCPNIPKENFTCL
TRLDHNRAIAQLAIKAKVPVTEVKNVILWGNHSLTMYPDHNHAHIEGQPAVDIYEEEWIK
NTFIPKVQKRGGEVLNLRQNSSVMSAAIAIRDHLVNWIYGTPEGQFVSMGVYTDGSFYDI
PADFVFSVPVKCKDFKYEVVKDLTISQFSRQKINISLRELQDEKEEANCYDDDAEDESEE