Identifiers and Description

Gene Model Identifier

TTHERM_01030010

Standard Name

PTK1 (Protein Tyrosine Kinase)

Aliases

PreTt10831 | 204.m00060

Description

PTK1 Serine/Threonine kinase domain protein; Putative insulin receptor-like tyrosine kinase; 66 kDa ciliary membrane protein- tyrosine phosphorylated in response to insulin; sequence similarity to DAF2- a C.elegans insulin receptor; contains SH2/SH3 domain binding motifs

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

Gene Ontology Annotations

Molecular Function

• glutathionylspermidine synthase activity (IEA) | GO:0008885
• obsolete red-sensitive opsin (ISS) | GO:0015061 | Ref:12546802

Biological Process

• adaxial/abaxial axis specification (IEA) | GO:0009943
• courtship behavior (IEA) | GO:0007619
• positive regulation of viral genome replication (ISS) | GO:0045070 | Ref:12546802
• regulation of juvenile hormone metabolic process (IEA) | GO:0007556

Domains

• ( PF00069 ) protein kinase domain
• ( PF07714 ) protein tyrosine kinase

Gene Expression Profile

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_10498.1	9.997093137033517e-262
	Description: protein kinase domain-containing protein (557 aa)
Oxytricha	Contig16193.0.g77	3.000712232670428e-104
	Description: Protein kinase domain
DictyBase	DDB_G0270814	7.999270105144775e-57
	Description: nek2 on chromosome: 1 position 4847143 to 4848761
Stentor Coeruleus	SteCoe_11057	4.590938473882946e-48
	Description: None
SGD	YAR018C	2.0000236365077126e-43
	Description: KIN3 Nonessential serine/threonine protein kinase; possible role in DNA damage response
WormBase	WBGene00008956	2.0008536325002377e-42
	Description: locus:nekl-3 status:Confirmed UniProt:G5EFM9 protein_id:CAA92169.2

General Information

No Data fetched for General Information

Associated Literature

1. Ref:16850526: Csaba G, Kovács P, Pállinger E (2007) Effect of starvation on insulin production and insulin binding in Tetrahymena. Cell biochemistry and function 25(4):473-7
2. Ref:16611747: Wloga D, Camba A, Rogowski K, Manning G, Jerka-Dziadosz M, Gaertig J (2006) Members of the NIMA-related kinase family promote disassembly of cilia by multiple mechanisms. Molecular biology of the cell 17(6):2799-810
3. Ref:12546802: Christensen ST, Guerra CF, Awan A, Wheatley DN, Satir P (2003) Insulin receptor-like proteins in Tetrahymena thermophila ciliary membranes. Current biology : CB 13(2):R50-2

Sequences

>TTHERM_01030010(coding)
ATGCAAAATTCACAATCTCAAATTACTGACTTTGAAATACTAAAGCGTCTTGGTGAAGGT
TCTTTTGGGTCTGTCTACTAGGTTAAGAGAAAAAGTGATGAGAAGATTTATGCCATGAAA
AAGGTTAAAATGATGTCTCTTTCAACCAAGGAAAAGGAGAATGCCTTAAATGAAGTGCGT
ATCCTTGCTTCCATCAAAAGCGACAATATTATCAGCTACAAAGAAGCTTTTTATGACGAA
AAGTCATCCACATTATGCATAATCATGGAGTTTGCAACAAAAGGTGATGTTTTATAATAA
ATTAGTGAAAAGAAGAAGAAACATTCTTATTTTGAAGAAAACCTTATTTGGAAATATGCA
GCAGATATGCTCTTGGGACTAAAGTCCCTTCATGATATGAAAATTCTACACAGAGACTTG
AAAGGAGCAAACGTTTTCATTGCAGAAGATGGGTCATTAAAGCTTGGAGATTTGAATGTT
TCCAAAGTTTAAAAGAGAGATTTTGCCTACACCTAAACAGGAACACCATATTATACCTCT
CCTGAAGTTTGGTAAAATCGTCCATATGATTCTAAATGTGATGTCTGGTCTTTAGGATGT
GTATTATATGAAATAGTCACTCTTGAACCACCCTTTAAAGGCACTTCCATGGAAGATCTC
TATAAAAGAGTCTTGAGAGGCAACTTTTCTCCAATCAACTTGTAAAGATACAGCTCTGAC
CTCTAGAAGTTCATCGAGTCATGCTTAAAAGTTGAGCCTAAAATGAGATCTTCAGTAGAG
TCTCTATTAAACCATAAGTGCATAATGCCTCATCTAAAACCAGAACAGATAGCCATGCTC
GAAAAGAAGAAAAAGGAAAAAATAGATTTATTGCAGACCATCAAGCTTCCTTATGGAAAC
AACTTGAAAGAAATTAACAAGCGCTTACCCAAATCAAATTATGACATATTAGATGAAAAA
ATAGAAGAATATGAGCAAGAAATAAAAACTGATTAAATTCGTCTTAAGAAAAAAAATGAA
GACCGTCCCTACTCAGCAGTGGATCCTACAAGTAATTTAATAAAAAATAACTTAGCATAA
AAGCCAAGCGAAAACCCAATTTAAAGACCTAGAGATAATTCAGCCCATAACAACAACAAC
AACAATAATAATAACTATTATAATTATTCTCCACAACCAAATAATAGATTATAGTCAGCT
CAACCCTAAGTAAAAAGAGTTTTAAGCAATAACGATCTAGGAGTTATTAATAATCCAGGA
AAGTACTATATGCCTCCAATTGGCAATAATTAACAAAAATACAATTATCACTATTATAAT
TAAGAGAAGCCTTATTAACCTAAAATTGCGATCCACTAGCAAAAAGACTCAGTTTACAAT
AATGGCGGAATTCAAAGATATAACTCAAAAGAGGTACTTTATAAAAATGCTGAATAAATT
GTTGGAAGAGTCAGAAAATCTACCGATGATCTATTAGAAAATAATAGAAATTATGTTAAC
CAAAGACCTCCTTCTAATTATTATTCTAATGATAATAAAGGTATTCCAAAACCAAAACTC
CAACCCTTAAATAACATTCCTAAAATTCCTGGCTCACCTTAAGTCAATAACAATGCAAAT
TTACCACCAAAACCATTCAGAAATTATTGA

>TTHERM_01030010(gene)
ATGCAAAATTCACAATCTCAAATTACTGACTTTGAAATACTAAAGCGTCTTGGTGAAGGT
TCTTTTGGGTCTGTCTACTAGGTTAAGAGAAAAAGTGATGAGAAGATTTATGCCATGAAA
AAGGTTAAAATGATGTCTCTTTCAACCAAGGAAAAGGAGAATGCCTTAAATGAAGTGCGT
ATCCTTGCTTCCATCAAAAGCGACAATATTATCAGCTACAAAGAAGCTTTTTATGACGAA
AAGTCATCCACATTATGCATAATCATGGAGTTTGCAACAAAAGGTGATGTTTTATAATAA
ATTAGTGAAAAGAAGAAGAAACATTCTTATTTTGAAGAAAACCTTATTTGGAAATATGCA
GCAGATATGCTCTTGGGACTAAAGTCCCTTCATGATATGAAAATTCTACACAGAGACTTG
AAAGGAGCAAACGTTTTCATTGCAGAAGATGGGTCATTAAAGCTTGGAGATTTGAATGTT
TCCAAAGTTTAAAAGAGAGATTTTGCCTACACCTAAACAGGAACACCATATTATACCTCT
CCTGAAGTTTGGTAAAATCGTCCATATGATTCTAAATGTGATGTCTGGTCTTTAGGATGT
GTATTATATGAAATAGTCACTCTTGAACCACCCTTTAAAGGCACTTCCATGGAAGATCTC
TATAAAAGAGTCTTGAGAGGCAACTTTTCTCCAATCAACTTGTAAAGATACAGCTCTGAC
CTCTAGAAGTTCATCGAGTCATGCTTAAAAGTTGAGCCTAAAATGAGATCTTCAGTAGAG
TCTCTATTAAACCATAAGTGCATAATGCCTCATCTAAAACCAGAACAGATAGCCATGCTC
GAAAAGAAGAAAAAGGAAAAAATAGATTTATTGCAGACCATCAAGCTTCCTTATGGAAAC
AACTTGAAAGAAATTAACAAGCGCTTACCCAAATCAAATTATGACATATTAGATGAAAAA
ATAGAAGAATATGAGCAAGAAATAAAAACTGATTAAATTCGTCTTAAGAAAAAAAATGAA
GACCGTCCCTACTCAGCAGTGGATCCTACAAGTAATTTAATAAAAAATAACTTAGCATAA
AAGCCAAGCGAAAACCCAATTTAAAGACCTAGAGATAATTCAGCCCATAACAACAACAAC
AACAATAATAATAACTATTATAATTATTCTCCACAACCAAATAATAGATTATAGTCAGCT
CAACCCTAAGTAAAAAGAGTTTTAAGCAATAACGATCTAGGAGTTATTAATAATCCAGGA
AAGTACTATATGCCTCCAATTGGCAATAATTAACAAAAATACAATTATCACTATTATAAT
TAAGAGAAGCCTTATTAACCTAAAATTGCGATCCACTAGCAAAAAGACTCAGTTTACAAT
AATGGCGGAATTCAAAGATATAACTCAAAAGAGGTACTTTATAAAAATGCTGAATAAATT
GTTGGAAGAGTCAGAAAATCTACCGATGATCTATTAGAAAATAATAGAAATTATGTTAAC
CAAAGACCTCCTTCTAATTATTATTCTAATGATAATAAAGGTATTCCAAAACCAAAACTC
CAACCCTTAAATAACATTCCTAAAATTCCTGGCTCACCTTAAGTCAATAACAATGCAAAT
TTACCACCAAAACCATTCAGAAATTATTGA

>TTHERM_01030010(protein)
MQNSQSQITDFEILKRLGEGSFGSVYQVKRKSDEKIYAMKKVKMMSLSTKEKENALNEVR
ILASIKSDNIISYKEAFYDEKSSTLCIIMEFATKGDVLQQISEKKKKHSYFEENLIWKYA
ADMLLGLKSLHDMKILHRDLKGANVFIAEDGSLKLGDLNVSKVQKRDFAYTQTGTPYYTS
PEVWQNRPYDSKCDVWSLGCVLYEIVTLEPPFKGTSMEDLYKRVLRGNFSPINLQRYSSD
LQKFIESCLKVEPKMRSSVESLLNHKCIMPHLKPEQIAMLEKKKKEKIDLLQTIKLPYGN
NLKEINKRLPKSNYDILDEKIEEYEQEIKTDQIRLKKKNEDRPYSAVDPTSNLIKNNLAQ
KPSENPIQRPRDNSAHNNNNNNNNNYYNYSPQPNNRLQSAQPQVKRVLSNNDLGVINNPG
KYYMPPIGNNQQKYNYHYYNQEKPYQPKIAIHQQKDSVYNNGGIQRYNSKEVLYKNAEQI
VGRVRKSTDDLLENNRNYVNQRPPSNYYSNDNKGIPKPKLQPLNNIPKIPGSPQVNNNAN
LPPKPFRNY