Identifiers and Description

Gene Model Identifier

TTHERM_01030010

Standard Name

PTK1 (Protein Tyrosine Kinase)

Aliases

PreTt10831 | 204.m00060

Description

PTK1 Serine/Threonine kinase domain protein; Putative insulin receptor-like tyrosine kinase; 66 kDa ciliary membrane protein, tyrosine phosphorylated in response to insulin; sequence similarity to DAF2, a C. elegans insulin receptor; contains SH2/SH3 domain binding motifs; hypothetical protein

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Molecular Function

• SH2 domain binding (ISS) | GO:0042169
• SH3 domain binding (ISS) | GO:0017124

Domains

No Data fetched for Domains

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

No Data fetched for Homologs

General Information

No Data fetched for General Information

Associated Literature

1. Ref:16850526: Csaba G, Kovács P, Pállinger E (2007) Effect of starvation on insulin production and insulin binding in Tetrahymena. Cell biochemistry and function 25(4):473-7
2. Ref:16611747: Wloga D, Camba A, Rogowski K, Manning G, Jerka-Dziadosz M, Gaertig J (2006) Members of the NIMA-related kinase family promote disassembly of cilia by multiple mechanisms. Molecular biology of the cell 17(6):2799-810
3. Ref:12546802: Christensen ST, Guerra CF, Awan A, Wheatley DN, Satir P (2003) Insulin receptor-like proteins in Tetrahymena thermophila ciliary membranes. Current biology : CB 13(2):R50-2

Sequences

>TTHERM_01030010(coding)
ATGCAAAATTCACAATCTCAAATTACTGACTTTGAAATACTAAAGCGTCTTGGTGAAGGT
TCTTTTGGGTCTGTCTACTAGGTTAAGAGAAAAAGTGATGAGAAGATTTATGCCATGAAA
AAGGTTAAAATGATGTCTCTTTCAACCAAGGAAAAGGAGAATGCCTTAAATGAAGTGCGT
ATCCTTGCTTCCATCAAAAGCGACAATATTATCAGCTACAAAGAAGCTTTTTATGACGAA
AAGTCATCCACATTATGCATAATCATGGAGTTTGCAACAAAAGGTGATGTTTTATAATAA
ATTAGTGAAAAGAAGAAGAAACATTCTTATTTTGAAGAAAACCTTATTTGGAAATATGCA
GCAGATATGCTCTTGGGACTAAAGTCCCTTCATGATATGAAAATTCTACACAGAGACTTG
AAAGGAGCAAACGTTTTCATTGCAGAAGATGGGTCATTAAAGCTTGGAGATTTGAATGTT
TCCAAAGTTTAAAAGAGAGATTTTGCCTACACCTAAACAGGAACACCATATTATACCTCT
CCTGAAGTTTGGTAAAATCGTCCATATGATTCTAAATGTGATGTCTGGTCTTTAGGATGT
GTATTATATGAAATAGTCACTCTTGAACCACCCTTTAAAGGCACTTCCATGGAAGATCTC
TATAAAAGAGTCTTGAGAGGCAACTTTTCTCCAATCAACTTGTAAAGATACAGCTCTGAC
CTCTAGAAGTTCATCGAGTCATGCTTAAAAGTTGAGCCTAAAATGAGATCTTCAGTAGAG
TCTCTATTAAACCATAAGTGCATAATGCCTCATCTAAAACCAGAACAGATAGCCATGCTC
GAAAAGAAGAAAAAGGAAAAAATAGATTTATTGCAGACCATCAAGCTTCCTTATGGAAAC
AACTTGAAAGAAATTAACAAGCGCTTACCCAAATCAAATTATGACATATTAGATGAAAAA
ATAGAAGAATATGAGCAAGAAATAAAAACTGATTAAATTCGTCTTAAGAAAAAAAATGAA
GACCGTCCCTACTCAGCAGTGGATCCTACAAGTAATTTAATAAAAAATAACTTAGCATAA
AAGCCAAGCGAAAACCCAATTTAAAGACCTAGAGATAATTCAGCCCATAACAACAACAAC
AACAATAATAATAACTATTATAATTATTCTCCACAACCAAATAATAGATTATAGTCAGCT
CAACCCTAAGTAAAAAGAGTTTTAAGCAATAACGATCTAGGAGTTATTAATAATCCAGGA
AAGTACTATATGCCTCCAATTGGCAATAATTAACAAAAATACAATTATCACTATTATAAT
TAAGAGAAGCCTTATTAACCTAAAATTGCGATCCACTAGCAAAAAGACTCAGTTTACAAT
AATGGCGGAATTCAAAGATATAACTCAAAAGAGGTACTTTATAAAAATGCTGAATAAATT
GTTGGAAGAGTCAGAAAATCTACCGATGATCTATTAGAAAATAATAGAAATTATGTTAAC
CAAAGACCTCCTTCTAATTATTATTCTAATGATAATAAAGGTATTCCAAAACCAAAACTC
CAACCCTTAAATAACATTCCTAAAATTCCTGGCTCACCTTAAGTCAATAACAATGCAAAT
TTACCACCAAAACCATTCAGAAATTATTGA

>TTHERM_01030010(gene)
ATTTATGTAATATTTAAAAAATGTATATGTATTAATAAGTAAAAAAGATCAAAAATTAAT
TTTGTTTTAAGGCTCATAGAAAAGAAATAAAGCTGTTCATTACCATCTCAAAAAAAAATA
TCAAAAAAACATTAATATAATTAGTAAGTAATTCATCAAAAAAAAAAAATAGATAAAAAA
TACGAAGAAAATAATAGTGTAGCTACTAATTATTTAAAATTAAGCATTACGAAAAATTGA
TAAACTCCATATTTTTAAAGCGTTTTTAGTTTATAAGGCACTCAAACAAATCTAATCGGT
TCCAAAAATCTCAAGATCTGTTTATTTCATAATAGGAAAGCGTTAGAGAGATACTTTATC
ATACAAGTTAGAACAAAAACTTTACTCAAATATTACTTATTAGATTGTAGGATAATTTAA
AATAATAAATTTGAAATGCAAAATTCACAATCTCAAATTACTGACTTTGAAATACTAAAG
CGTCTTGGTGAAGGTTCTTTTGGGTCTGTCTACTAGGTTAAGAGAAAAAGTGATGAGAAG
ATTTATGCCATGAAAAAGGTTAAAATGATGTCTCTTTCAACCAAGGAAAAGGAGAATGCC
TTAAATGAAGTGCGTATCCTTGCTTCCATCAAAAGCGACAATATTATCAGCTACAAAGAA
GCTTTTTATGACGAAAAGTCATCCACATTATGCATAATCATGGAGTTTGCAACAAAAGGT
GATGTTTTATAATAAATTAGTGAAAAGAAGAAGAAACATTCTTATTTTGAAGAAAACCTT
ATTTGGAAATATGCAGCAGATATGCTCTTGGGACTAAAGTCCCTTCATGATATGAAAATT
CTACACAGAGACTTGAAAGGAGCAAACGTTTTCATTGCAGAAGATGGGTCATTAAAGCTT
GGAGATTTGAATGTTTCCAAAGTTTAAAAGAGAGATTTTGCCTACACCTAAACAGGAACA
CCATATTATACCTCTCCTGAAGTTTGGTAAAATCGTCCATATGATTCTAAATGTGATGTC
TGGTCTTTAGGATGTGTATTATATGAAATAGTCACTCTTGAACCACCCTTTAAAGGCACT
TCCATGGAAGATCTCTATAAAAGAGTCTTGAGAGGCAACTTTTCTCCAATCAACTTGTAA
AGATACAGCTCTGACCTCTAGAAGTTCATCGAGTCATGCTTAAAAGTTGAGCCTAAAATG
AGATCTTCAGTAGAGTCTCTATTAAACCATAAGTGCATAATGCCTCATCTAAAACCAGAA
CAGATAGCCATGCTCGAAAAGAAGAAAAAGGAAAAAATAGATTTATTGCAGACCATCAAG
CTTCCTTATGGAAACAACTTGAAAGAAATTAACAAGCGCTTACCCAAATCAAATTATGAC
ATATTAGATGAAAAAATAGAAGAATATGAGCAAGAAATAAAAACTGATTAAATTCGTCTT
AAGAAAAAAAATGAAGACCGTCCCTACTCAGCAGTGGATCCTACAAGTAATTTAATAAAA
AATAACTTAGCATAAAAGCCAAGCGAAAACCCAATTTAAAGACCTAGAGATAATTCAGCC
CATAACAACAACAACAACAATAATAATAACTATTATAATTATTCTCCACAACCAAATAAT
AGATTATAGTCAGCTCAACCCTAAGTAAAAAGAGTTTTAAGCAATAACGATCTAGGAGTT
ATTAATAATCCAGGAAAGTACTATATGCCTCCAATTGGCAATAATTAACAAAAATACAAT
TATCACTATTATAATTAAGAGAAGCCTTATTAACCTAAAATTGCGATCCACTAGCAAAAA
GACTCAGTTTACAATAATGGCGGAATTCAAAGATATAACTCAAAAGAGGTACTTTATAAA
AATGCTGAATAAATTGTTGGAAGAGTCAGAAAATCTACCGATGATCTATTAGAAAATAAT
AGAAATTATGTTAACCAAAGACCTCCTTCTAATTATTATTCTAATGATAATAAAGGTATT
CCAAAACCAAAACTCCAACCCTTAAATAACATTCCTAAAATTCCTGGCTCACCTTAAGTC
AATAACAATGCAAATTTACCACCAAAACCATTCAGAAATTATTGAATGAATAATAATAAA
AATTTCTTGCTAAAATGTAATTAAATAATATATACATTATTTTCTATCTATTTCTATTTA
GTGATATTAATTTATAAATTCACTGTTTATTACAATATTTTATTGTATTCCTTTATGTAT
CTATAGTTCCTCCCTTCTTATTTTTCATAATTAATTAATCAATTAAATTACAAAAATATA
TTTTGATTTCAATAAAA

>TTHERM_01030010(protein)
MQNSQSQITDFEILKRLGEGSFGSVYQVKRKSDEKIYAMKKVKMMSLSTKEKENALNEVR
ILASIKSDNIISYKEAFYDEKSSTLCIIMEFATKGDVLQQISEKKKKHSYFEENLIWKYA
ADMLLGLKSLHDMKILHRDLKGANVFIAEDGSLKLGDLNVSKVQKRDFAYTQTGTPYYTS
PEVWQNRPYDSKCDVWSLGCVLYEIVTLEPPFKGTSMEDLYKRVLRGNFSPINLQRYSSD
LQKFIESCLKVEPKMRSSVESLLNHKCIMPHLKPEQIAMLEKKKKEKIDLLQTIKLPYGN
NLKEINKRLPKSNYDILDEKIEEYEQEIKTDQIRLKKKNEDRPYSAVDPTSNLIKNNLAQ
KPSENPIQRPRDNSAHNNNNNNNNNYYNYSPQPNNRLQSAQPQVKRVLSNNDLGVINNPG
KYYMPPIGNNQQKYNYHYYNQEKPYQPKIAIHQQKDSVYNNGGIQRYNSKEVLYKNAEQI
VGRVRKSTDDLLENNRNYVNQRPPSNYYSNDNKGIPKPKLQPLNNIPKIPGSPQVNNNAN
LPPKPFRNY