Identifiers and Description

Gene Model Identifier

TTHERM_01080600

Standard Name

CDK5 (Cyclin-Dependent Kinase)

Aliases

PreTt02102 | 222.m00058 | 3798.m00215 | MicNup98A | g1456 | TTHERM_01080603 | g1456

Description

CDK5 cyclin-dependent kinase; Serine/threonine-protein kinase Atg1-like

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Cellular Component

• aleurone grain membrane (IEA) | GO:0032578
• chloroplast ribosome (IEA) | GO:0043253
• clathrin-sculpted acetylcholine transport vesicle lumen (IEA) | GO:0060202
• CURI complex (IEA) | GO:0032545
• Dbf4-dependent protein kinase complex (IEA) | GO:0031431
• EGFR-Grb2-Sos complex (IEA) | GO:0070620
• multivesicular body (IEA) | GO:0005771
• obsolete ectoplasm (IEA) | GO:0043265
• vacuolar membrane (IEA) | GO:0005774

Molecular Function

• 17alpha-hydroxyprogesterone binding (IEA) | GO:1903880
• 2-octaprenyl-6-methoxyphenol hydroxylase activity (IEA) | GO:0008681
• 2-oxoglutarate decarboxylase activity (IEA) | GO:0008683
• 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity (IEA) | GO:0008413
• ADP phosphatase activity (IEA) | GO:0043262
• aromatase activity (IEA) | GO:0008402
• arsenate reductase (glutaredoxin) activity (IEA) | GO:0008794
• axon guidance receptor activity (IEA) | GO:0008046
• C-5 sterol desaturase activity (IEA) | GO:0000248
• carboxymethylenebutenolidase activity (IEA) | GO:0008806
• ferric triacetylfusarinine C:proton symporter activity (IEA) | GO:0015346
• L-aspartate oxidase activity (IEA) | GO:0008734
• microtubule severing ATPase activity (IEA) | GO:0008568
• N-acetyl-gamma-aminoadipyl-phosphate reductase activity (IEA) | GO:0043870
• obsolete aminoacetone:oxygen oxidoreductase(deaminating) activity (IEA) | GO:0052594
• obsolete DNA topoisomerase IV activity (IEA) | GO:0008724
• obsolete proprotein convertase 2 activator activity (IEA) | GO:0016484
• obsolete protein tagging activity (IEA) | GO:0008638
• obsolete RNA polymerase I transcription regulator recruiting activity (IEA) | GO:0001186
• obsolete sodium-transporting two-sector ATPase activity (IEA) | GO:0015443
• obsolete tachykinin (IEA) | GO:0008648
• phosphatidylcholine:cardiolipin O-linoleoyltransferase activity (IEA) | GO:0032577
• phosphatidylserine decarboxylase activity (IEA) | GO:0004609
• phosphoethanolamine N-methyltransferase activity (IEA) | GO:0000234
• rhamnulose-1-phosphate aldolase activity (IEA) | GO:0008994
• Ser(Gly)-tRNA(Ala) hydrolase activity (IEA) | GO:0043908
• sphingomyelin phosphodiesterase activity (IEA) | GO:0004767
• sterol 14-demethylase activity (IEA) | GO:0008398
• tubulin-glutamic acid ligase activity (IEA) | GO:0070740
• type 4 neuropeptide Y receptor binding (IEA) | GO:0031844

Biological Process

• absorption of visible light (IEA) | GO:0016038
• bud dilation involved in lung branching (IEA) | GO:0060503
• budding cell bud growth (IEA) | GO:0007117
• budding cell isotropic bud growth (IEA) | GO:0007119
• cell migration in diencephalon (IEA) | GO:0061381
• cell wall modification involved in fruit ripening (IEA) | GO:0009829
• cellular response to D-galactose (IEA) | GO:1905378
• cellular response to phosphate starvation (IEA) | GO:0016036
• epithelial cell proliferation involved in lung bud dilation (IEA) | GO:0060505
• epithelium development (IEA) | GO:0060429
• female courtship behavior (IEA) | GO:0008050
• gamma-tubulin complex assembly (IEA) | GO:1902481
• germinal center formation (IEA) | GO:0002467
• heme A biosynthetic process (IEA) | GO:0006784
• heme biosynthetic process (IEA) | GO:0006783
• induction of apoptosis by extracellular signals (IEA) | GO:0008624
• inferior colliculus development (IEA) | GO:0061379
• interleukin-28A secretion (IEA) | GO:0072628
• lung connective tissue development (IEA) | GO:0060427
• mesonephric podocyte cell fate commitment (IEA) | GO:0061258
• negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process (IEA) | GO:1902642
• negative regulation of complement-dependent cytotoxicity (IEA) | GO:1903660
• negative regulation of double-strand break repair via nonhomologous end joining (IEA) | GO:2001033
• negative regulation of epithelial cell-cell adhesion involved in epithelium migration (IEA) | GO:1903682
• negative regulation of PERK-mediated unfolded protein response (IEA) | GO:1903898
• obsolete fertilization, exchange of chromosomal proteins (IEA) | GO:0035042
• obsolete negative regulation of response to extracellular stimulus (IEA) | GO:0032105
• obsolete positive regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process (IEA) | GO:1902964
• obsolete regulation of 1-deoxy-D-xylulose-5-phosphate synthase activity (IEA) | GO:1902395
• obsolete regulation of glucose-6-phosphatase activity (IEA) | GO:0032114
• obsolete reproduction (IEA) | GO:0000003
• ommochrome biosynthetic process (IEA) | GO:0006727
• P granule disassembly (IEA) | GO:1903864
• peripheral tolerance induction (IEA) | GO:0002465
• phagocytosis (IEA) | GO:0006909
• plant-type cell wall modification (IEA) | GO:0009827
• positive regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process (IEA) | GO:1902643
• positive regulation of intestinal epithelial cell development (IEA) | GO:1905300
• positive regulation of peroxisome proliferator activated receptor signaling pathway (IEA) | GO:0035360
• positive regulation of protein autoubiquitination (IEA) | GO:1902499
• positive regulation of response to water deprivation (IEA) | GO:1902584
• positive regulation of wound healing, spreading of epidermal cells (IEA) | GO:1903691
• priming of cellular response to stress (IEA) | GO:0080136
• propan-2-ol biosynthetic process (IEA) | GO:1902640
• protein localization to old growing cell tip (IEA) | GO:1903858
• quercetin biosynthetic process (IEA) | GO:1901734
• quercetin metabolic process (IEA) | GO:1901732
• regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process (IEA) | GO:1902646
• regulation of cellular glucuronidation (IEA) | GO:2001029
• regulation of complement-dependent cytotoxicity (IEA) | GO:1903659
• regulation of cytokinin dehydrogenase activity (IEA) | GO:1903856
• regulation of interleukin-27-mediated signaling pathway (IEA) | GO:0070107
• regulation of L-arginine import into cell (IEA) | GO:1902826
• regulation of macropinocytosis (IEA) | GO:1905301
• release of sequestered calcium ion into cytosol by endoplasmic reticulum (IEA) | GO:1903514
• response to oxygen radical (IEA) | GO:0000305
• response to reactive oxygen species (IEA) | GO:0000302
• sperm aster formation (IEA) | GO:0035044
• sterol regulatory element binding protein cleavage involved in ER-nuclear sterol response pathway (IEA) | GO:0006992
• sterol regulatory element binding protein import into nucleus involved in sterol depletion response (IEA) | GO:0006993
• synaptic vesicle docking (IEA) | GO:0016081
• vacuolar acidification (IEA) | GO:0007035

Domains

• ( PF00069 ) Protein kinase domain

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

No Data fetched for Homologs

General Information

No Data fetched for General Information

Associated Literature

1. Ref:25788697: Iwamoto M, Koujin T, Osakada H, Mori C, Kojidani T, Matsuda A, Asakawa H, Hiraoka Y, Haraguchi T (2015) Biased assembly of the nuclear pore complex is required for somatic and germline nuclear differentiation in Tetrahymena. Journal of cell science 128(9):1812-23
2. Ref:19375312: Iwamoto M, Mori C, Kojidani T, Bunai F, Hori T, Fukagawa T, Hiraoka Y, Haraguchi T (2009) Two distinct repeat sequences of Nup98 nucleoporins characterize dual nuclei in the binucleated ciliate tetrahymena. Current biology : CB 19(10):843-7

Sequences

>TTHERM_01080600(coding)
ATGCGTCTCCTTTATAATAGAAAAGAAAATTTAAAGTTTTGCTTAAAACAGCCTCAAGTA
ACACCCAAAGAAGTAAGAGAAGCAAACAATTTTTCTTTAGAATACTTAAAAAAATAGATT
CACTTAATATTTATTGTAAAAAAAATGGATTAAAGATATAATAACCCTCCTTATAGCAAT
TAATAATAATACTATAATAATAATACAATAAATAGAGTACCAATTACATAACATAATGCT
TACAATTACCAAGGAATCAACAATGTTCCTGGCCAATAAAATAGGTATATAAGCATGAAT
CAATAACCAAGTAGCTAGAATTATCAGCAAAGATAATATTACCAGCAACCAACAGTAAAC
TAATAATAGATTTAATAATAACAATAAAGATAATAAGCTTTTAGCTAGAAAACAATAAGC
TCGGAAGGGTTTAAGAGACTTCTGAAAACAAAATACATAATGGCAAATGAAATTGGTAAA
GGTTCATTTGCTAAGGTATTTAAAGGCATAAATAGTGAAACAGGTGAAAAAGTTGCTATA
AAAAAGATTGACAAGAATAAATTTGATAAGCAGTATTTAGAATTAATTGATAGTGAGATA
TCAGTGCTTTCTTAACTTAATAATGAGCATATAATTAAGTTTTTAGATCTCTTCAACGAA
GGAGATTATATTTATATTGTTACTGAGTTGTGCGAATTGGGTGATTTGGAAGTTTTCATC
AAAAATAATTTTTCGGCTACCAAACTTAGATTGCCTGAAGAATTAGTCAAAGTTTTCGCA
TATTAAATACTCTTGGCTTTCTTAGGTATAGCAGATATGAATATCATACATCGTGATATG
AAACTAGCCAATGTATTAATTACAAAAGATTTTCACTTAAAAGTTGCTGACTTTGGCCTA
GCCAAATCCAGCTTTGAAAAAGATAAAGATTAGGTTGGTACTCCTATGACTATGGCTCCA
GAAGTATTAAATAATCTAGGATATGATAGCAGATGTGATGTTTGGTCTGTAGGCTGTATG
ATCTATGAAATGCTTGAAGGCCGTGCTCCTTTTTTGCCTACGAATAATGGAGGTATTGAA
GAACTCAAAAGACTGATAAATTAAAGATAGCTTATTTTTAGGTAGAATATTTCTTAGAGT
GCATAAAATCTAATAGATTAAATGTTAACTCTCAACCCTAAAAAACGTATTAGCTGGCAT
GAAATGTTCAACCATGAGTGGTTTGCTGAGTGTATATCCTAAGGTGAGCCTTACATTTAA
AAAGTATCAAAAGACTATTCTAATTTTGTTCTTATCGAAGAGTAGCATCTAGACCCAGAA
TTTGCGTTAGAATTTGGTTTACTTTTAAGAGATTTCGTTAATTATCATGTAGATACTTTT
TACATAGAAATAAAAAAATGTAGAGATACCTTATCCACTTTTTATAATGACCCTAAATTC
CCTGCAGGTAATAAAGGAGCCAACTAGTAACTTCTTTCAACTGTTTTAAAAAATATAGAC
ATACTAATAGCTCTACTTTACAACCATTAATTTACTTTTAAATTCAAAAATTAAGTTGAA
ATACTACAAATCACAAAATTCTGCAAGCAAAAAATGCAATTATAATATAAAAAAGACTTA
TACGAATTCGCAATAAATAATAATATAAAACCAGTAAAATTATAGGAAACAATAGGAAAT
GAATTATTTTAATTGAGTAATAATGTAATGGAAGGAGATTTTGATTACTTCAAATGCAAT
TTTACATCTATAATTAATCTAATAAATGTCTTAAGTAATCCAACCAAAGGATTCTTGAAA
GAAATAATAATAGATGAGTCACGCCTCACAGAAGAATAAAATAATCGAATTTTATTTATT
AATTTTTCAAAAGCTTACTATGAAGAATTCAATTCCCAATAAGAAATAAATAAATAAATT
GTTTTCAATAGAACTTTCATCCAAACTTAGTTTTAAGAAAAGGAATAGAATAGATATGAC
CAAATAGTTTTATTGAGTGAAATAGTATTTGGATATTAACAAGAAGTGATAAGTCATAAT
AGCTAGATATAATAATAATAATAATATCAATAAGATAAAGGAAATAGAATCAGAGATTAT
TAATAAAACTATTGA

>TTHERM_01080600(gene)
CTAAAAATTAAAATCTAAAAGGCATATTGATATACATTAAAAAAATTATACTTACAATAT
AAACCAGTAAATAAGTAAACAAACAGTGATATTGATTTGTACTATCTTATCTCAATCTTT
TGTTTTCTCTGATAATGGCACAAAAAAATTTGCTCTAGGATTAACTATTTTAAAAGTATT
TTCTTAAACCAGTCAAAATAGGTTCAGGTCTCTCCTATGCGTCTCCTTTATAATAGAAAA
GAAAATTTAAAGTTTTGCTTAAAACAGCCTCAAGTAACACCCAAAGAAGTAAGAGAAGCA
AACAATTTTTCTTTAGAATACTTAAAAAAATAGATTCACTTAATATTTATTGTAAAAAAA
ATGGATTAAAGATATAATAACCCTCCTTATAGCAATTAATAATAATACTATAATAATAAT
ACAATAAATAGAGTACCAATTACATAACATAATGCTTACAATTACCAAGGAATCAACAAT
GTTCCTGGCCAATAAAATAGGTATATAAGCATGAATCAATAACCAAGTAGCTAGAATTAT
CAGCAAAGATAATATTACCAGCAACCAACAGTAAACTAATAATAGATTTAATAATAACAA
TAAAGATAATAAGCTTTTAGCTAGAAAACAATAAGCTCGGAAGGGTTTAAGAGACTTCTG
AAAACAAAATACATAATGGCAAATGAAATTGGTAAAGGTTCATTTGCTAAGGTATTTAAA
GGCATAAATAGTGAAACAGGTGAAAAAGTTGCTATAAAAAAGATTGACAAGAATAAATTT
GATAAGCAGTATTTAGAATTAATTGATAGTGAGATATCAGTGCTTTCTTAACTTAATAAT
GAGCATATAATTAAGTTTTTAGATCTCTTCAACGAAGGAGATTATATTTATATTGTTACT
GAGTTGTGCGAATTGGGTGATTTGGAAGTTTTCATCAAAAATAATTTTTCGGCTACCAAA
CTTAGATTGCCTGAAGAATTAGTCAAAGTTTTCGCATATTAAATACTCTTGGCTTTCTTA
GGTATAGCAGATATGAATATCATACATCGTGATATGAAACTAGCCAATGTATTAATTACA
AAAGATTTTCACTTAAAAGTTGCTGACTTTGGCCTAGCCAAATCCAGCTTTGAAAAAGAT
AAAGATTAGGTTGGTACTCCTATGACTATGGCTCCAGAAGTATTAAATAATCTAGGATAT
GATAGCAGATGTGATGTTTGGTCTGTAGGCTGTATGATCTATGAAATGCTTGAAGGCCGT
GCTCCTTTTTTGCCTACGAATAATGGAGGTATTGAAGAACTCAAAAGACTGATAAATTAA
AGATAGCTTATTTTTAGGTAGAATATTTCTTAGAGTGCATAAAATCTAATAGATTAAATG
TTAACTCTCAACCCTAAAAAACGTATTAGCTGGCATGAAATGTTCAACCATGAGTGGTTT
GCTGAGTGTATATCCTAAGGTGAGCCTTACATTTAAAAAGTATCAAAAGACTATTCTAAT
TTTGTTCTTATCGAAGAGTAGCATCTAGACCCAGAATTTGCGTTAGAATTTGGTTTACTT
TTAAGAGATTTCGTTAATTATCATGTAGATACTTTTTACATAGAAATAAAAAAATGTAGA
GATACCTTATCCACTTTTTATAATGACCCTAAATTCCCTGCAGGTAATAAAGGAGCCAAC
TAGTAACTTCTTTCAACTGTTTTAAAAAATATAGACATACTAATAGCTCTACTTTACAAC
CATTAATTTACTTTTAAATTCAAAAATTAAGTTGAAATACTACAAATCACAAAATTCTGC
AAGCAAAAAATGCAATTATAATATAAAAAAGACTTATACGAATTCGCAATAAATAATAAT
ATAAAACCAGTAAAATTATAGGAAACAATAGGAAATGAATTATTTTAATTGAGTAATAAT
GTAATGGAAGGAGATTTTGATTACTTCAAATGCAATTTTACATCTATAATTAATCTAATA
AATGTCTTAAGTAATCCAACCAAAGGATTCTTGAAAGAAATAATAATAGATGAGTCACGC
CTCACAGAAGAATAAAATAATCGAATTTTATTTATTAATTTTTCAAAAGCTTACTATGAA
GAATTCAATTCCCAATAAGAAATAAATAAATAAATTGTTTTCAATAGAACTTTCATCCAA
ACTTAGTTTTAAGAAAAGGAATAGAATAGATATGACCAAATAGTTTTATTGAGTGAAATA
GTATTTGGATATTAACAAGAAGTGATAAGTCATAATAGCTAGATATAATAATAATAATAA
TATCAATAAGATAAAGGAAATAGAATCAGAGATTATTAATAAAACTATTGAAATTTCTTT
ATTATTAAATAAATTCATCATAAATTACTCAAAAATAAAATTTAGAATTTTTAACTAAAT
TTTTTCCCAATCTTTTTTATACATTCATGCAATAAGTACTAGTATCAAAAATCATAATAA
CCTCTTGGTTGTATGAAAAAATTTAAATTCTTAAATGTACACTAATAAATAAAAAAAGCA
AGCAAGCCACCGATTATATTTATTCTCTTTTTTTTTTACTTAAAAAGTATTATTTGTATC
TTTTTCTATCGTTTTTATTATTGTAAACAAA

>TTHERM_01080600(protein)
MRLLYNRKENLKFCLKQPQVTPKEVREANNFSLEYLKKQIHLIFIVKKMDQRYNNPPYSN
QQQYYNNNTINRVPITQHNAYNYQGINNVPGQQNRYISMNQQPSSQNYQQRQYYQQPTVN
QQQIQQQQQRQQAFSQKTISSEGFKRLLKTKYIMANEIGKGSFAKVFKGINSETGEKVAI
KKIDKNKFDKQYLELIDSEISVLSQLNNEHIIKFLDLFNEGDYIYIVTELCELGDLEVFI
KNNFSATKLRLPEELVKVFAYQILLAFLGIADMNIIHRDMKLANVLITKDFHLKVADFGL
AKSSFEKDKDQVGTPMTMAPEVLNNLGYDSRCDVWSVGCMIYEMLEGRAPFLPTNNGGIE
ELKRLINQRQLIFRQNISQSAQNLIDQMLTLNPKKRISWHEMFNHEWFAECISQGEPYIQ
KVSKDYSNFVLIEEQHLDPEFALEFGLLLRDFVNYHVDTFYIEIKKCRDTLSTFYNDPKF
PAGNKGANQQLLSTVLKNIDILIALLYNHQFTFKFKNQVEILQITKFCKQKMQLQYKKDL
YEFAINNNIKPVKLQETIGNELFQLSNNVMEGDFDYFKCNFTSIINLINVLSNPTKGFLK
EIIIDESRLTEEQNNRILFINFSKAYYEEFNSQQEINKQIVFNRTFIQTQFQEKEQNRYD
QIVLLSEIVFGYQQEVISHNSQIQQQQQYQQDKGNRIRDYQQNY