Identifiers and Description

Gene Model Identifier

TTHERM_01104960

Standard Name

BLT1 (Beta-Like Tubulin 1)

Aliases

PreTt01888 | 235.m00039

Description

BLT1 tubulin; Highly divergent beta-like tubulin; present in very low abundance; localizes to small subset of microtubules; not incorporated into growing ciliary axonemes

Genome Browser (Macronucleus)

Full Screen View


Genome Browser (Micronucleus)

Full Screen View

External Links

Gene Ontology Annotations

Cellular Component

Molecular Function

Biological Process

Domains

  • ( PF00091 ) Tubulin/FtsZ family, GTPase domain
  • ( PF03953 ) Tubulin C-terminal domain

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

Tetrahymena Stock Center

  • ( SD02243 ) Macronucleus: BTU1(AA 1-428) with BLT at C terminus (AA 428-473) followed by HA tag, inserted into the MTT1 locus. Neo2 upstream of MTT1 5’ region
  • ( SD02244 ) Macronucleus: BTU1(AA 1-428) with BLT at C terminus (AA 428-473) followed by HA tag, inserted into the MTT1 locus. Neo2 upstream of MTT1 5’ region
  • ( SD02245 ) Macronucleus: BTU1(AA 1-428) with BLT at C terminus (AA 428-473) followed by HA tag, inserted into the MTT1 locus. Neo2 upstream of MTT1 5’ region
  • ( SD02246 ) Micronucleus: Neo3 replaces BLT coding
  • ( SD02247 ) Micronucleus: Neo3 replaces BLT coding
  • ( SD02248 ) Micronucleus: Neo3 replaces BLT coding
  • ( SD02249 ) Micronucleus: Neo3 replaces BLT coding
  • ( SD02250 ) Micronucleus: Neo3 replaces BLT coding
  • ( SD02251 ) Micronucleus: Neo3 replaces BLT coding
  • ( SD02252 ) Micronucleus: Neo3 replaces BLT coding
  • ( SD02253 ) Micronucleus: Neo3 replaces BLT coding
  • ( SD02254 ) Micronucleus: Neo3 replaces BLT coding
  • ( SD02255 ) Micronucleus: Neo3 replaces BLT coding
  • ( SD02256 ) Micronucleus: Neo3 replaces BLT coding
  • ( SD02257 ) Micronucleus: Neo3 replaces BLT coding
  • ( SD02258 ) Micronucleus: Neo3 replaces BLT coding
  • ( SD02259 ) Micronucleus: Neo3 replaces BLT coding
  • ( SD02260 ) Macronucleus: BLT1(AA 1-428) withBTU1 at C terminus (AA 429-443) followed by HA tag, inserted into the MTT1 locus. Neo2 upstream of MTT1 5’ region
  • ( SD02261 ) Macronucleus: BLT1(AA 1-428) withBTU1 at C terminus (AA 429-443) followed by HA tag, inserted into the MTT1 locus. Neo2 upstream of MTT1 5’ region
  • ( SD02262 ) Macronucleus: BLT1(AA 1-428) withBTU1 at C terminus (AA 429-443) followed by HA tag, inserted into the MTT1 locus. Neo2 upstream of MTT1 5’ region
  • ( SD02562 ) Macronucleus: BLT1with c-terminal HA replaces MTTi coding with neo2 upsteam in Mtt1 5’ flanking region
  • ( SD02563 ) Macronucleus: BLT1with c-terminal HA replaces MTTi coding with neo2 upsteam in Mtt1 5’ flanking region
  • ( SD02564 ) Macronucleus: BLT1with c-terminal HA replaces MTTi coding with neo2 upsteam in Mtt1 5’ flanking region
  • ( SD02565 ) Macronucleus: BLT1with c-terminal HA replaces MTTi coding with neo2 upsteam in Mtt1 5’ flanking region
  • ( SD02566 ) Macronucleus: BLT1with c-terminal HA replaces MTTi coding with neo2 upsteam in Mtt1 5’ flanking region
  • ( SD02567 ) Macronucleus: BLT1with c-terminal HA replaces MTTi coding with neo2 upsteam in Mtt1 5’ flanking region

Homologs

Source Identifier Score
Stentor Coeruleus SteCoe_5719 0
Description: None
WormBase WBGene00006538 9.997093137033517e-262
Description: locus:tbb-4 Tubulin beta-4 chain status:Partially_confirmed UniProt:P41937 protein_id:CAA86310.1
Tetrahymena borealis EI9_16521.1 9.997093137033517e-262
Description: tubulin/FtsZ family, GTPase domain-containing protein (472 aa)
DictyBase DDB_G0269196 9.997093137033517e-262
Description: tubB on chromosome: 1 position 3261649 to 3263130
Oxytricha Contig8792.0.g74 9.997093137033517e-262
Description: Tubulin/FtsZ family, GTPase domain
SGD YFL037W 9.997093137033517e-262
Description: TUB2 Beta-tubulin; associates with alpha-tubulin (Tub1p and Tub3p) to form tubulin dimer, which polymerizes to form microtubules
WormBase WBGene00021461 9.997093137033517e-262
Description: locus:nekl-1 status:Partially_confirmed UniProt:Q6AW07 protein_id:CCD69902.1
Tetrahymena borealis EI9_03028.1 9.997093137033517e-262
Description: hypothetical protein (113 aa)

General Information

No Data fetched for General Information

Associated Literature

  1. Ref:16933976: Eisen JA, Coyne RS, Wu M, Wu D, Thiagarajan M, Wortman JR, Badger JH, Ren Q, Amedeo P, Jones KM, Tallon LJ, Delcher AL, Salzberg SL, Silva JC, Haas BJ, Majoros WH, Farzad M, Carlton JM, Smith RK, Garg J, Pearlman RE, Karrer KM, Sun L, Manning G, Elde NC, Turkewitz AP, Asai DJ, Wilkes DE, Wang Y, Cai H, Collins K, Stewart BA, Lee SR, Wilamowska K, Weinberg Z, Ruzzo WL, Wloga D, Gaertig J, Frankel J, Tsao CC, Gorovsky MA, Keeling PJ, Waller RF, Patron NJ, Cherry JM, Stover NA,
  2. Ref:11891286: Shang Y, Song X, Bowen J, Corstanje R, Gao Y, Gaertig J, Gorovsky MA (2002) A robust inducible-repressible promoter greatly facilitates gene knockouts, conditional expression, and overexpression of homologous and heterologous genes in Tetrahymena thermophila. Proceedings of the National Academy of Sciences of the United States of America 99(6):3734-9

Sequences 

>TTHERM_01104960(coding)
ATGAGAGAAATTGTTTGCATTTCAGCAGGTCAATGCGGTAACTAAATAGGATATAAGTTC
TGGGAAAGAGTTTCTCAAGAGCATGGAGTCGAAGAGACTGGTCTGTATAACGGAAATAAT
GACTTATAGCTCGAGAGAATTGATGTTTACTATAATGAAGGCTCAAGTGGACGTTATGTA
CCTAGATCAGTAATGGTTGATTTGGAACCTGGTGTATTGGATTCAATTCGTGCATCAAAA
TACAGATAACTTTTCCATCCTGATAATTTCATTCACGCTCAAAGTAGCGCTTCTAATAAT
TGGGCTAAGGGACACTATTCTGAAGGTGCTGAACTTTAATAGGAAGTTTTAGATATTGTC
CGTAGAGAAGTTGAAGGTTGTGACAGCCTATAAGGTTTCCAATTCACTCATTCTATTGGT
GGAGGCACTGGAAGTGGTATGGGCACTTTGCTTATTTAAAAGCTTAGAGAAGAATATCCA
GACAGAATTTTTTCAAGTTTTTCTGTTTTCCCATCCGTAAAAGTAAGCGATGTTGTAATT
GAACCTTATAATGCTACATTGAGCATTCATTAGCTCATAGAAAATGTTGACTAATGCATG
GTTATAGATAATGAAGCTTTATACAATATTTGCATGAAAAATTTAAAGATTGAACACCCT
ACTTATGGTGACCTCAATCATATTGTCTCTGTAGCTATGTCTGGTGTTACTTGCAGTATG
AGATTCCCTGGATAATTAAATGCAGATCTCAGAAAATTGTCAGTTAATTTGACTCCCTTC
CCTCGTTTACACTTCTTTACAGTTGGAATAGCTCCTTTATATGGAAGAGGATAGGCTTAG
TTTGCCAGTAAATATGATGTTCCTGAAATTCTTTAGCAAGCTTTTAATCCTCACAATATG
ATGTGTGCTGCCGATGTTTCTCATGGAAAATATTTAACAGCTGCTCTTGCTTTTAGAGGA
AAAGTATCATCATATGAAATCGAAAAGCAACTACTAAACTTCTAACAAAAAAATAGCAAC
CGTTTTACAGAATGGATTCCAAACAGTATGAAGCTAAGTATGTGCGATATATCCTTGGAA
TAAGTACCAAGAAGCGCTGTTTTAATAAGTAATAACACATCGATATAAGAAGTATTCAAA
AGAATAAATGCTTAATATACAAGCATGTTTAGAAGAAAGGCTTTCGTTCACTGGTATTTA
GATGAAGGTATGGACGAAATGGAGTTTAATGAAGCAGAAGCTAATATGAATGACTTGGTG
AGTGAATATCAATAATACTAAGATTCAACCGTAGACAGTGAAGAAGAAATTGACTTAGAT
TAGACATAGGCAACATTTGGAGAAAGATAAGAAAAACAAAATAAAAAATGTAACTCAAAA
TAACAATCTAATATTGCTTCATCAAATGAAATTTGA


>TTHERM_01104960(gene)
ATGAGAGAAATTGTTTGCATTTCAGCAGGTCAATGCGGTAACTAAATAGGATATAAGTTC
TGGGAAAGAGTTTCTCAAGAGCATGGAGTCGAAGAGACTGGTCTGTATAACGGAAATAAT
GACTTATAGCTCGAGAGAATTGATGTTTACTATAATGAAGGCTCAAGTGGACGTTATGTA
CCTAGATCAGTAATGGTTGATTTGGAACCTGGTGTATTGGATTCAATTCGTGCATCAAAA
TACAGATAACTTTTCCATCCTGATAATTTCATTCACGCTCAAAGTAGCGCTTCTAATAAT
TGGGCTAAGGGACACTATTCTGAAGGTGCTGAACTTTAATAGGAAGTTTTAGATATTGTC
CGTAGAGAAGTTGAAGGTTGTGACAGCCTATAAGGTTTCCAATTCACTCATTCTATTGGT
GGAGGCACTGGAAGTGGTATGGGCACTTTGCTTATTTAAAAGCTTAGAGAAGAATATCCA
GACAGAATTTTTTCAAGTTTTTCTGTTTTCCCATCCGTAAAAGTAAGCGATGTTGTAATT
GAACCTTATAATGCTACATTGAGCATTCATTAGCTCATAGAAAATGTTGACTAATGCATG
GTTATAGATAATGAAGCTTTATACAATATTTGCATGAAAAATTTAAAGATTGAACACCCT
ACTTATGGTGACCTCAATCATATTGTCTCTGTAGCTATGTCTGGTGTTACTTGCAGTATG
AGATTCCCTGGATAATTAAATGCAGATCTCAGAAAATTGTCAGTTAATTTGACTCCCTTC
CCTCGTTTACACTTCTTTACAGTTGGAATAGCTCCTTTATATGGAAGAGGATAGGCTTAG
TTTGCCAGTAAATATGATGTTCCTGAAATTCTTTAGCAAGCTTTTAATCCTCACAATATG
ATGTGTGCTGCCGATGTTTCTCATGGAAAATATTTAACAGCTGCTCTTGCTTTTAGAGGA
AAAGTATCATCATATGAAATCGAAAAGCAACTACTAAACTTCTAACAAAAAAATAGCAAC
CGTTTTACAGAATGGATTCCAAACAGTATGAAGCTAAGTATGTGCGATATATCCTTGGAA
TAAGTACCAAGAAGCGCTGTTTTAATAAGTAATAACACATCGATATAAGAAGTATTCAAA
AGAATAAATGCTTAATATACAAGCATGTTTAGAAGAAAGGCTTTCGTTCACTGGTATTTA
GATGAAGGTATGGACGAAATGGAGTTTAATGAAGCAGAAGCTAATATGAATGACTTGGTG
AGTGAATATCAATAATACTAAGATTCAACCGTAGACAGTGAAGAAGAAATTGACTTAGAT
TAGACATAGGCAACATTTGGAGAAAGATAAGAAAAACAAAATAAAAAATGTAACTCAAAA
TAACAATCTAATATTGCTTCATCAAATGAAATTTGA


>TTHERM_01104960(protein)
MREIVCISAGQCGNQIGYKFWERVSQEHGVEETGLYNGNNDLQLERIDVYYNEGSSGRYV
PRSVMVDLEPGVLDSIRASKYRQLFHPDNFIHAQSSASNNWAKGHYSEGAELQQEVLDIV
RREVEGCDSLQGFQFTHSIGGGTGSGMGTLLIQKLREEYPDRIFSSFSVFPSVKVSDVVI
EPYNATLSIHQLIENVDQCMVIDNEALYNICMKNLKIEHPTYGDLNHIVSVAMSGVTCSM
RFPGQLNADLRKLSVNLTPFPRLHFFTVGIAPLYGRGQAQFASKYDVPEILQQAFNPHNM
MCAADVSHGKYLTAALAFRGKVSSYEIEKQLLNFQQKNSNRFTEWIPNSMKLSMCDISLE
QVPRSAVLISNNTSIQEVFKRINAQYTSMFRRKAFVHWYLDEGMDEMEFNEAEANMNDLV
SEYQQYQDSTVDSEEEIDLDQTQATFGERQEKQNKKCNSKQQSNIASSNEI