Identifiers and Description

Gene Model Identifier

TTHERM_01107420

Standard Name

PCNA1 (proliferating cell nuclear antigen 1)

Aliases

PreTt28091 | 237.m00048 | 3794.m00183

Description

PCNA1 proliferating cell nuclear antigen; proliferating cell nuclear antigen (pcna)

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Cellular Component

• PCNA complex (IEA) | GO:0043626

Molecular Function

• DNA binding (IEA) | GO:0003677
• DNA polymerase processivity factor activity (IEA) | GO:0030337

Biological Process

• regulation of DNA replication (IEA) | GO:0006275

Domains

No Data fetched for Domains

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_20275.1	3.9987282255476324e-176
	Description: proliferating cell nuclear antigen (pcna) (262 aa)
Oxytricha	Contig12091.0.g3	8.003265703977305e-104
	Description: Proliferating cell nuclear antigen, N-terminal domain
WormBase	WBGene00003955	2.9993408039826107e-81
	Description: locus:pcn-1 Proliferating cell nuclear antigen status:Confirmed UniProt:O02115 protein_id:CCD66765.1
Tetrahymena borealis	EI9_20685.1	2.9993408039826107e-81
	Description: SWIB/MDM2 domain-containing protein (558 aa)
DictyBase	DDB_G0287607	2.0001503375893664e-79
	Description: pcna on chromosome: 5 position 463300 to 464157
SGD	YBR088C	3.0000115468388957e-66
	Description: POL30 Proliferating cell nuclear antigen (PCNA), functions as the sliding clamp for DNA polymerase delta; may function as a docking site for other proteins required for mitotic and meiotic chromosomal DNA replication and for DNA repair
Stentor Coeruleus	SteCoe_31816	4.0795586671775603e-41
	Description: None

General Information

No Data fetched for General Information

Associated Literature

1. Ref:23884606: Gao S, Xiong J, Zhang C, Berquist BR, Yang R, Zhao M, Molascon AJ, Kwiatkowski SY, Yuan D, Qin Z, Wen J, Kapler GM, Andrews PC, Miao W, Liu Y (2013) Impaired replication elongation in Tetrahymena mutants deficient in histone H3 Lys 27 monomethylation. Genes & development 27(15):1662-79

Sequences

>TTHERM_01107420(coding)
ATGTTTGAAGCTAAATTACAATAAGGTGTTATTTTCAAAAAAATCGTCGATGCTATCAAG
GATTTAGTTAAATCAGTTAATATCGATGCTAGCACTAGTGGTCTTTCCATGCAAGCTATG
GATTCAGCTCACGTTGCTTTGGTTTCCCTCAAGTTAAATGAAAATGGTTTCAAGGATTAT
AGATGTGACAGACCAATCACTCTTGGTCTTTCTATTGAAAACCTTTCCAAGATCCTCAAG
TGTGCTGGAAATGATGACACTATTACCTTATAAACTGATGAAGAAGAACCTTCTTCCCTT
AAATTCTTCTTTGAAAATTAATAGGCCTCTAAGATCTCCGAATTTAGTTTGAACTTAATG
TCATTAGATAGTGAATCTTTGGGTATCCCCGACACCGATTATTCTTCTGTTATTCAAATG
TCCTCAGCTGAATTCTCTAGAATCTGCAAGGAACTTAGTTCTATTTCTGAAACAGTTGAA
ATTGAAACTAGCAAAGAATCTGTTAAGTTTAGCGTTTAAGGAGATATTGGTGCTGGTTCA
ATCACTGTCAAGAATAACTAAAGTGATAAAGATGTTGACCGTGTTGATTTACAAATTGAT
TAACCCGTTAAGTTAACCTTCGCTCTTAGATATTTGAATATGTTCAATAAGGCTGTCTCT
CTTAGCAGTACTGTTAGTTTAAATATGTCTGAAGAAAATCCTCTTATGGTTGAATATAAA
ATCGATGATCTTGGTTCTCTTAGATTCTATCTTGCTCCTAAGATTTCTGATGAAGAAAGT
AGTTGA

>TTHERM_01107420(gene)
ATGTTTGAAGCTAAATTACAATAAGGTGTTATTTTCAAAAAAATCGTCGATGCTATCAAG
GATTTAGTTAAATCAGTTAATATCGATGCTAGCACTAGTGGTCTTTCCATGCAAGCTATG
GATTCAGCTCACGTTGCTTTGGTTTCCCTCAAGTTAAATGAAAATGGTTTCAAGGATTAT
AGATGTGACAGACCAATCACTCTTGGTCTTTCTATTGAAAACCTTTCCAAGATCCTCAAG
TGTGCTGGAAATGATGACACTATTACCTTATAAACTGATGAAGAAGAACCTTCTTCCCTT
AAATTCTTCTTTGAAAATTAATGTAATTTATTAGGACAAAAATAATTATTTTATTCTAAA
CTTTGTACATGTTTTCTTTTGGAATAAATTAAACTGAACATATTTAGAATACTCTACTTT
TACAATACTCTACTTTTATAATATTATATAATATATCCTTATTCATTCTATTAATCATTT
GATACAATTTTTTCAATGCTAATCAAAATTAAAATTATTTTTTTTATTATTTTGTAGAGG
CCTCTAAGATCTCCGAATTTAGTTTGAACTTAATGTCATTAGATAGTGAATCTTTGGGTA
TCCCCGACACCGATTATTCTTCTGTTATTCAAATGTCCTCAGCTGAATTCTCTAGAATCT
GCAAGGAACTTAGTTCTATTTCTGAAACAGGTAAACAATAATAGATGTTAAATTCAAAGA
AGTAGATCATACTTAATCTAGATAATAATGTTTAAACTTAAAAATTAAGAAGTAGCTCTT
AAAAATTTTGAAAATTAGTTAAGTTAAGTATGGTTGACCTTCACTAAATGCATTAGATTA
TTATTAGATATATAAATTAATATTGTTTTTAAAAAATAAAATAGTTGAAATTGAAACTAG
CAAAGAATCTGTTAAGTTTAGCGTTTAAGGAGATATTGGTGCTGGTTCAATCACTGTCAA
GAATAACTAAAGTGATAAAGATGTTGACCGTGTTGATTTACAAATTGATTAACCCGTTAA
GTTAACCTTCGCTCTTAGATATTTGAATATGTTCAATAAGGCTGTCTCTCTTAGCAGTAC
TGTTAGTTTAAATATGTCTGAAGAAAATCCTCTTATGGTTGAATATAAAATCGATGATCT
TGGTTCTCTTAGATTCTATCTTGCTCCTAAGATTTCTGATGAAGAAAGTAGTTGA

>TTHERM_01107420(protein)
MFEAKLQQGVIFKKIVDAIKDLVKSVNIDASTSGLSMQAMDSAHVALVSLKLNENGFKDY
RCDRPITLGLSIENLSKILKCAGNDDTITLQTDEEEPSSLKFFFENQQASKISEFSLNLM
SLDSESLGIPDTDYSSVIQMSSAEFSRICKELSSISETVEIETSKESVKFSVQGDIGAGS
ITVKNNQSDKDVDRVDLQIDQPVKLTFALRYLNMFNKAVSLSSTVSLNMSEENPLMVEYK
IDDLGSLRFYLAPKISDEESS