Identifiers and Description

Gene Model Identifier

TTHERM_01114180

Standard Name

NRK35 (NIMA-Related Kinase )

Aliases

PreTt01924 | 240.m00047

Description

NRK35 Serine/Threonine kinase domain protein; NIMA-Related Kinase

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Molecular Function

• ATP binding (IEA) | GO:0005524
• protein kinase activity (IEA) | GO:0004672
• protein tyrosine kinase activity (IEA) | GO:0004713

Biological Process

• protein phosphorylation (IEA) | GO:0006468

Domains

• ( PF00069 ) Protein kinase domain
• ( PF07714 ) Protein tyrosine and serine/threonine kinase

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_19400.1	9.997093137033517e-262
	Description: protein kinase domain-containing protein (976 aa)
Tetrahymena borealis	EI9_12944.1	9.997093137033517e-262
	Description: hypothetical protein (148 aa)
DictyBase	DDB_G0289277	9.996162112727537e-67
	Description: nek4 on chromosome: 5 position 2561379 to 2563106
Oxytricha	Contig6078.0.1.g70	4.0015855602347305e-61
	Description: Protein kinase domain
WormBase	WBGene00021461	2.000704504372864e-47
	Description: locus:nekl-1 status:Partially_confirmed UniProt:Q6AW07 protein_id:CCD69902.1
SGD	YHR102W	1.000137892321693e-31
	Description: KIC1 Protein kinase of the PAK/Ste20 family, required for cell integrity; physically interacts with Cdc31p (centrin), which is a component of the spindle pole body; part of the RAM network that regulates cellular polarity and morphogenesis
Stentor Coeruleus	SteCoe_3063	1.603810890548638e-28
	Description: None

General Information

No Data fetched for General Information

Associated Literature

1. Ref:16611747: Wloga D, Camba A, Rogowski K, Manning G, Jerka-Dziadosz M, Gaertig J (2006) Members of the NIMA-related kinase family promote disassembly of cilia by multiple mechanisms. Molecular biology of the cell 17(6):2799-810

Sequences

>TTHERM_01114180(coding)
ATGGAGAAATATGACAAAGTTAAGTTAGTGTGTAAAATTGAAATGGGAGATGTATTTCTA
GTAGAAGAGAAAACTTCAAAGCATAAATATATCATGAAGAGGATTTTTATTGATGAAAGG
GAATAGTAAACCTATCACCCAGAAAATGAAGCTAAATTACTTGAATAGCTTGACCATCCA
AATATTATAAAAATGCAGGAACATTTTTATCATAAAAAATATTTTTGCTTAATTATGGAG
TTTGCAGAAAAAGGCGATTTAAATAAATTGATCTTAAACCTCAAACAAAAAGAAGAATAT
TTAAATGAAAAGCAGGTATTAGACCTATTCTGTTAGCTCTGCCTAGCTGTTAAGTATCTT
CATGACAGAAAATACATTCATAGGGATATAAAAATACATAACATATTCCTCTCTAATGAG
AATATTGTGAAATTAGGAGATTTTGGGATATCAATTTAGCTAGATAAAAGCGAGATATAT
GCTAAGACATAGCTAGGAACTCCATATTATTTATCTCCTGAAGTAGTCTAAGGAAAGAAC
TATGATTAAAAAGTTGACATTTGGATGATTGGTTGTTTTTTATATGAAATTTGTGAATTA
TCAAGACCATTTTAAGGTGCTACTTGGTCTGAAGTTGATTACAAAATATAAAATATTGAA
CCAGAGCCTATAGATGAATCATATAGCTAATTTTTATAAAATCTAGTTAAAAAGCTTCTT
TAAAAAGATCCTCAATAACGGCCAAGTATAAATGACATTATAGAAATGCCAGAAATTATA
CAAAATCTTAAATAAATGTCTAAGGACGAAGTTTATTCTTAATATTTGATATTCCCTGAA
TTTATTTATCAGGATGAAGAAGAAGAAGAAAATGAACATGAAAAAACAGTGATTAAAGAC
AATGAAAACTATTGTAAGGCAGAAAAAAATATAGAAAGTATTTTAAAAAACGTAGAAGAG
GAGCAACTTGCAAAATATTCTTTATCTTATTTGTTGAAGAAAGCTGCTTAAAGTGTATAA
AAAGAAGAGATGCTCTTAAAAAAATAAAAATAAGATAAATTAGAACAAAAAAAATAATTT
TCTATAAATGGAGATTAAAGCGAATAACTGGAAAATAGTAAAATCAATTAAGAAATTCTT
TATACATAAAATTTAAATAATACAAAAGACTCTCAATAAGTGAAGAAAAATAAATTTTAG
TAAAAATTTTATGAGAAAAAAAAGCAGGAATTAAATATTTGCACGATTAATGGCTAAGAA
GATGAATAATCCAATATTATTACTCAATCTTAATAGTCTAAAAATATCTAAAAAAATGCT
TCAGCCCCAACCACAACAAAACCAAATCAAAAGCATTTAGCAAATGTTTCATAAATACCA
AAAGAGTCATATGTAAATTATGAACCAGTTGGAATAGATTTACCATGTAATGATGATTCA
AGCACTAAAATAACTTCATATAATTAAAAAGAAACTTAAAATCTAACACCAGAATAGAAT
ATTAAATAAATTTCACAAATTTCTTAAACAACACAAAACACAATAGATTCTACTCCTAAT
AGATTAAAAGTTAATGAATTAAAAGATTAAAACTAAGATAAAAGTACCTAATTTTTGTAA
GAAAAAGTTATGTAAAACAACTCTAATTTGTCATAATTAACTTCAGCTTCGAATAATTAA
AAGCCTACTGCAAACTAAGAGATATAAAGCCTTAATTAATAAATTATAAATACCAATCTA
GTAGAACATAATAATTCTAATGATTAAAAAGTGCCCTGTAATGGATAACCAACCACTAAA
TAAAATTAGCAAAGCTTTAGCTTTTCAGCTAATTAGTATGCAAATCTACTTAAAACTCCT
CAACTTCCTAACACAATACTTTTTACTTAGTTTTTAAAGGAAAAATTAGGAAAAGAGAAG
TTTACTAAAATGAAATATTTGCTTGAAGGTAGTTAAAATCCTCTTAAACTTCTTGATGAA
AATACTGAGCTAATTACTGAAATAATTGGACCAGAAAATATTGATTGCATTAATTATTTT
AGATGCTTAATCACCAGTAGCGTTACACCACCTGGTAGTCACTTCAGAGCCCGCTCAACT
GCCAATTCTCCTTGCTAAACCTTAAATAAAAATTTATTACCATAACCTTAGCATTCAAAT
TAGGGAGTTTAAGCATTTTAAATTCATCTCAAAAGCGCTAATTAAAATGAACAACAATAA
CAAATGATTTAACTTTAGAAATAAGGATCTTTGCAATAACAATAGCATCAAATTCCTACA
ATTAGCAATAATTCATCATATGTTTAAGGTTTCCATCAATATAATAACAACAATATACAA
AATAATAACCACCATATTTATAGAAACTAAAGTGTTTACTCTTAACATTCCTAATAAGGC
TAAATGTCTGTTGGAAGTTCTCCTTAATATTTTAACAATAGTAGCAATAGAATATTTGAA
AATAATTTTAATTTATTTTAAAGTTGTAATAACGATAAAAATTCTTTTTAATCAGAATGG
TCATACATTTTGAGCTAACCAGGAAATCTAAATTGTCAAAACACTCATTTAATAAATTAA
GGAAATGTTACCAGTAGCCTATCTAATAGAAATGCATAGTTTAGTAATAGCCAGCCTTAG
CAACAAAGCAGCTTTTAAATATATAATTAATAACAGTAGTAATTTATTTAAAATAAAATA
CCTTTAAACTCATATCAACTAAAGCAATTTCCAGCAAATCATAAAATCGCAAGCACGACT
CAAAATTAAAATTAAAAACAAATGTTTCACTCATCTCATTTTTATCAGTAATGA

>TTHERM_01114180(gene)
ATGGAGAAATATGACAAAGTTAAGTTAGTGTGTAAAATTGAAATGGGAGATGTATTTCTA
GTAGAAGAGAAAACTTCAAAGCATGTAAAATTTTAAGATTTGTTATTATATTCCATTTAA
TTTTCTACTTGTTAATATGCAATAATTATTATCTTGAATACTTCATTTTAAATAAAATTT
GGTTAATCTAAAAGAAATATATCATGAAGAGGATTTTTATTGATGAAAGGGAATAGTAAA
CCTATCACCCAGAAAATGAAGCTAAATTACTTGAATAGCTTGACCATCCAAATATTATAA
AAATGCAGGAACATTTTTATCATAAAAAATATTTTTGCTTAATTATGGAGTTTGCAGAAA
AAGGTAAACTAATGAATTTAAATTTAAAAATTATTTACTAACTTATGTATTTCAAAACCT
ATTCACTCTTTAAGTAATTTTTTTTCAAACAGGCGATTTAAATAAATTGATCTTAAACCT
CAAACAAAAAGAAGAATATTTAAATGAAAAGCAGGTATTTTTACTTTATCTGTTATTACT
AATTTCTCTAAATTACTCTAAAAACATAAAGAATTTGCAAATTAATATTTTTTTAAATAC
TTACTTTATTTTTTAAGGTATTAGACCTATTCTGTTAGCTCTGCCTAGCTGTTAAGTATC
TTCATGACAGAAAATACATTCATAGGGATATAAAAATACATAACATATTCCTCTCTAATG
AGAATATTGTAAAATTTTATTTGCTATAAATATGATAAAACGCTAATCTATGAAAACCTA
CATACAACTGAATAAAATTTAAAATTGTTATATTAATAGGTGAAATTAGGAGATTTTGGG
ATATCAATTTAGCTAGATAAAAGCGAGATATATGCTAAGACATAGCTAGGAACTCCATAT
TATTTATCTCCTGAAGTAGTCTAAGGAAAGAACTATGATTAAAAAGTTGACATTTGGATG
ATTGGTTGTTTTTTATATGAAATTTGTGAATTATCAAGACCATTTTAAGGTGCTACTTGG
TCTGTAATTTATTCAAAATTGTTATTATTAAAATTTTTGTATGAAAAAAAATATATTTTT
AACCAAAATTTAACTTTTAAAATAATCAAAAAAGGAAGTTGATTACAAAATATAAAATAT
TGAACCAGAGCCTATAGATGAATCATATAGCTAATTTTTATAAAATCTAGTTAAAAAGCT
TCTTTAAAAAGATCCTCAATAGTAATTTATTAAATTATTAATGGATAATTATTCTAATTC
ATATTTTTCTTTTTTGGTCAAAAAAATCTTAAAAGTCAATTTAAAAGTTAATTTAATTAT
TTTCATTATATAGACGGCCAAGTATAAATGACATTATAGAAATGCCAGAAATTATACAAA
ATCTTAAATAAATGTCTAAGGACGAAGTTTATTCTTAATATTTGATATTCCCTGAATTTA
TTTATCAGGATGAAGAAGAAGAAGAAAATGAACATGAAAAAACAGTGATTAAAGACAATG
AAAACTATTGTAAGGCAGAAAAAAATATAGAAAGTATTTTAAAAAACGTAGAAGAGGAGC
AACTTGCAAAATATTCTTTATCTTATTTGTTGAAGAAAGCTGCTTAAAGTGTATAAAAAG
AAGAGATGCTCTTAAAAAAATAAAAATAAGATAAATTAGAACAAAAAAAATAATTTTCTA
TAAATGGAGATTAAAGCGAATAACTGGAAAATAGTAAAATCAATTAAGAAATTCTTTATA
CATAAAATTTAAATAATACAAAAGACTCTCAATAAGTGAAGAAAAATAAATTTTAGTAAA
AATTTTATGAGAAAAAAAAGCAGGAATTAAATATTTGCACGATTAATGGCTAAGAAGATG
AATAATCCAATATTATTACTCAATCTTAATAGTCTAAAAATATCTAAAAAAATGCTTCAG
CCCCAACCACAACAAAACCAAATCAAAAGCATTTAGCAAATGTTTCATAAATACCAAAAG
AGTCATATGTAAATTATGAACCAGTTGGAATAGATTTACCATGTAATGATGATTCAAGCA
CTAAAATAACTTCATATAATTAAAAAGAAACTTAAAATCTAACACCAGAATAGAATATTA
AATAAATTTCACAAATTTCTTAAACAACACAAAACACAATAGATTCTACTCCTAATAGAT
TAAAAGTTAATGAATTAAAAGATTAAAACTAAGATAAAAGTACCTAATTTTTGTAAGAAA
AAGTTATGTAAAACAACTCTAATTTGTCATAATTAACTTCAGCTTCGAATAATTAAAAGC
CTACTGCAAACTAAGAGATATAAAGCCTTAATTAATAAATTATAAATACCAATCTAGTAG
AACATAATAATTCTAATGATTAAAAAGTGCCCTGTAATGGATAACCAACCACTAAATAAA
ATTAGCAAAGCTTTAGCTTTTCAGCTAATTAGTATGCAAATCTACTTAAAACTCCTCAAC
TTCCTAACACAATACTTTTTACTTAGTTTTTAAAGGAAAAATTAGGAAAAGAGAAGTTTA
CTAAAATGAAATATTTGCTTGAAGGTAGTTAAAATCCTCTTAAACTTCTTGATGAAAATA
CTGAGCTAATTACTGAAATAATTGGACCAGAAAATATTGATTGCATTAATTATTTTAGAT
GCTTAATCACCAGTAGCGTTACACCACCTGGTAGTCACTTCAGAGCCCGCTCAACTGCCA
ATTCTCCTTGCTAAACCTTAAATAAAAATTTATTACCATAACCTTAGCATTCAAATTAGG
GAGTTTAAGCATTTTAAATTCATCTCAAAAGCGCTAATTAAAATGAACAACAATAACAAA
TGATTTAACTTTAGAAATAAGGATCTTTGCAATAACAATAGCATCAAATTCCTACAATTA
GCAATAATTCATCATATGTTTAAGGTTTCCATCAATATAATAACAACAATATACAAAATA
ATAACCACCATATTTATAGAAACTAAAGTGTTTACTCTTAACATTCCTAATAAGGCTAAA
TGTCTGTTGGAAGTTCTCCTTAATATTTTAACAATAGTAGCAATAGAATATTTGAAAATA
ATTTTAATTTATTTTAAAGTTGTAATAACGATAAAAATTCTTTTTAATCAGAATGGTCAT
ACATTTTGAGCTAACCAGGAAATCTAAATTGTCAAAACACTCATTTAATAAATTAAGGAA
ATGTTACCAGTAGCCTATCTAATAGAAATGCATAGTTTAGTAATAGCCAGCCTTAGCAAC
AAAGCAGCTTTTAAATATATAATTAATAACAGTAGTAATTTATTTAAAATAAAATACCTT
TAAACTCATATCAACTAAAGCAATTTCCAGCAAATCATAAAATCGCAAGCACGACTCAAA
ATTAAAATTAAAAACAAATGTTTCACTCATCTCATTTTTATCAGTAATGA

>TTHERM_01114180(protein)
MEKYDKVKLVCKIEMGDVFLVEEKTSKHKYIMKRIFIDEREQQTYHPENEAKLLEQLDHP
NIIKMQEHFYHKKYFCLIMEFAEKGDLNKLILNLKQKEEYLNEKQVLDLFCQLCLAVKYL
HDRKYIHRDIKIHNIFLSNENIVKLGDFGISIQLDKSEIYAKTQLGTPYYLSPEVVQGKN
YDQKVDIWMIGCFLYEICELSRPFQGATWSEVDYKIQNIEPEPIDESYSQFLQNLVKKLL
QKDPQQRPSINDIIEMPEIIQNLKQMSKDEVYSQYLIFPEFIYQDEEEEENEHEKTVIKD
NENYCKAEKNIESILKNVEEEQLAKYSLSYLLKKAAQSVQKEEMLLKKQKQDKLEQKKQF
SINGDQSEQLENSKINQEILYTQNLNNTKDSQQVKKNKFQQKFYEKKKQELNICTINGQE
DEQSNIITQSQQSKNIQKNASAPTTTKPNQKHLANVSQIPKESYVNYEPVGIDLPCNDDS
STKITSYNQKETQNLTPEQNIKQISQISQTTQNTIDSTPNRLKVNELKDQNQDKSTQFLQ
EKVMQNNSNLSQLTSASNNQKPTANQEIQSLNQQIINTNLVEHNNSNDQKVPCNGQPTTK
QNQQSFSFSANQYANLLKTPQLPNTILFTQFLKEKLGKEKFTKMKYLLEGSQNPLKLLDE
NTELITEIIGPENIDCINYFRCLITSSVTPPGSHFRARSTANSPCQTLNKNLLPQPQHSN
QGVQAFQIHLKSANQNEQQQQMIQLQKQGSLQQQQHQIPTISNNSSYVQGFHQYNNNNIQ
NNNHHIYRNQSVYSQHSQQGQMSVGSSPQYFNNSSNRIFENNFNLFQSCNNDKNSFQSEW
SYILSQPGNLNCQNTHLINQGNVTSSLSNRNAQFSNSQPQQQSSFQIYNQQQQQFIQNKI
PLNSYQLKQFPANHKIASTTQNQNQKQMFHSSHFYQQ