Identifiers and Description

Gene Model Identifier

TTHERM_01141570

Standard Name

ICL1 (IsoCitrate Lyase 1)

Aliases

PreTt20062 | 251.m00042 | 3821.m00564

Description

ICL1 isocitrate lyase; Isocitrate lyase family protein; similar domain structure to yeast isocitrate lyase 1 (ICL1)

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Molecular Function

• catalytic activity (IEA) | GO:0003824

Biological Process

• metabolic process (IEA) | GO:0008152

Domains

No Data fetched for Domains

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_20883.1	9.997093137033517e-262
	Description: hypothetical protein (504 aa)
Oxytricha	Contig20680.0.g93	9.997093137033517e-262
	Description: Isocitrate lyase family
WormBase	WBGene00017640	9.997093137033517e-262
	Description: status:Partially_confirmed UniProt:Q19655 protein_id:CCD68327.1
SGD	YER065C	2.0007442334946695e-153
	Description: ICL1 Isocitrate lyase, catalyzes the formation of succinate and glyoxylate from isocitrate, a key reaction of the glyoxylate cycle; expression of ICL1 is induced by growth on ethanol and repressed by growth on glucose
WormBase	WBGene00001564	2.998830401637127e-79
	Description: locus:icl-1 status:Confirmed UniProt:Q8IA71 protein_id:CCD63239.1
WormBase	WBGene00007364	2.998830401637127e-79
	Description: locus:stdh-3 Putative steroid dehydrogenase 3 status:Partially_confirmed UniProt:Q17704 protein_id:CAB01115.2
DictyBase	DDB_G0273017	5.998439611888618e-47
	Description: DDB_G0273017 on chromosome: 2 position 2236569 to 2237975

General Information

No Data fetched for General Information

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_01141570(coding)
ATGGACGTTGAAGGAAAGAGACTCTAAGAAATCACTGCTGAAATCCAAAAATGGTGGACT
AACTCTCGTTGGGAAAATGTTGAAAGACCCTACTAAGCTTAAGATGTTGCCCGTTTAAGA
CCCACCATCCCCATGGACTACCCCTCCAACTACTAATCCAAGAAGATGTGGAAACTCTTG
AAGGAAGCCCAAGCCAACAAGGGATTCCACCACACTTTCGGTGCCTTAGACCCCGTTCAA
GTTATCAACTTATCCAAGTACTTGAGAACTGTCTACGTCTCTGGATGGTAATGCTCTGCC
ACTGCCTCCACTACTAATGAACCTGGTCCAGATTTTGCTGATTACCCTGCCAACACTGTC
CCCAACAAAGTTGACCAACTCTTCAAGGCTTAACTTTTACAAGACAGAATCCAAAATGAA
CAAAGAGCTCATTTGACCCCTGAATAAAGAGCTAAGACTCCCAGAGTTGACTACCTTGCT
CCTATGATTGCTGATGCTGATGCTGGTTTCGGTGGTATTACTTCAACCATGAAGTTAATT
AAGTTATTCATTGAAGCTGGTGCTGCTGGTATCCATCTTGAAGATTAAAGACCTGGTACC
AAGAAATGTGGTCACATGAGTGGTAAGGTCGTTGTCTCCACTCGCGAACACGTCAACAGA
TTAATTGCTTGCAGACTCCAAGCTGATATTATGGGAACTGATTTAATTATCCTCGCCAGA
ACTGATGCTTTATCTGCTAGACTTATTGACTCCAACTGTGACCCCGTTGACCACCCCTTC
ATCCTTGGTCTTTGCCCTGATGGTAAGGAAAGAACTTTCCCTAATGCAGGTCTTGAAGCT
ATCAAGGCTAAGTTCACTGGTGCTAAGGTCCAAGAAGTCACCAAGCTCTGGCTCTCTAAG
TGTTACGATCTTTCCCTCACTCAAGCCCACGAATACGCTAGAACTCTCGGTTTTGACTTC
CAATTCGACTGGGAAGCTCTCCGTTCATCTGAAGGTTTCTACTCCATTGACGGTTGTGTT
GAATTATGTGCTGCTCGTGCTAAGTAATATTTAAGATATGCTGATATGGTTTGGATGGAA
ACTCCTACTCCCTCTTTGGAAGTTGCTACTAAGTTCTCTACCTTGGTAAAGAATAACCAT
CCCACCAAATTATTGGCTTACAACCTTTCCCCCTCTTTCAACTGGTCTGCTTTCAACATG
TCCAATGCTCAAATCCAATCTTTCTGTGCTGACCTTGGTAGACTCGGATACACCTGGTAA
TTCATTACTTTAGCTGGTTTCCACTTGAATGCTCTCAAGTCTGAAAAGCTCTCTAAGGAT
CTTGCTGCCCGTGGTATGCTCGCCTACGTCGAAACTGTCCAAAGAAAGGAAGAAAAGCAC
AAAGTCGACCAACTCACCCACCAAAAATGGTCTGGTGCTAACTACGTTGATGCTTGCCAA
GCCCTTGTTCAACCCGAATCTCAAACCTTAGCCTCCTCCAAAGACTCTACTGAAAACTAA
TTCAAGCATTGA

>TTHERM_01141570(gene)
ATGGACGTTGAAGGAAAGAGACTCTAAGAAATCACTGCTGAAATCCAAAAATGGTGGACT
AACTCTCGTTGGGAAAATGTTGAAAGACCCTACTAAGCTTAAGATGTTGCCCGTTTAAGA
CCCACCATCCCCATGGACTACCCCTCCAACTACTAATCCAAGAAGATGTGGAAACTCTTG
AAGGAAGCCCAAGCCAACAAGGGATTCCACCACACTTTCGGTGCCTTAGACCCCGTTCAA
GTTATCAACTTATCCAAGTACTTGAGAACTGTCTACGTCTCTGGATGGTAATGCTCTGCC
ACTGCCTCCACTACTAATGAACCTGGTCCAGATTTTGCTGATTACCCTGCCAACACTGTC
CCCAACAAAGTTGACCAACTCTTCAAGGCTTAACTTTTACAAGACAGAATCCAAAATGAA
CAAAGAGCTCATTTGACCCCTGAATAAAGAGCTAAGACTCCCAGAGTTGACTACCTTGCT
CCTATGATTGCTGATGCTGATGCTGGTTTCGGTGGTATTACTTCAACCATGAAGTTAATT
AAGTTATTCATTGAAGCTGGTGCTGCTGGTATCCATCTTGAAGATTAAAGACCTGGTACC
AAGAAATGTGGTCACATGAGTGGTAAGGTCGTTGTCTCCACTCGCGAACACGTCAACAGA
TTAATTGCTTGCAGACTCCAAGCTGATATTATGGGAACTGATTTAATTATCCTCGCCAGA
ACTGATGCTTTATCTGCTAGACTTATTGACTCCAACTGTGACCCCGTTGACCACCCCTTC
ATCCTTGGTCTTTGCCCTGATGGTAAGGAAAGAACTTTCCCTAATGCAGGTCTTGAAGCT
ATCAAGGCTAAGTTCACTGGTGCTAAGGTCCAAGAAGTCACCAAGCTCTGGCTCTCTAAG
TGTTACGATCTTTCCCTCACTCAAGCCCACGAATACGCTAGAACTCTCGGTTTTGACTTC
CAATTCGACTGGGAAGCTCTCCGTTCATCTGAAGGTTTCTACTCCATTGACGGTTGTGTT
GAATTATGTGCTGCTCGTGCTAAGTAATATTTAAGATATGCTGATATGGTTTGGATGGAA
ACTCCTACTCCCTCTTTGGAAGTTGCTACTAAGTTCTCTACCTTGGTAAAGAATAACCAT
CCCACCAAATTATTGGCTTACAACCTTTCCCCCTCTTTCAACTGGTCTGCTTTCAACATG
TCCAATGCTCAAATCCAATCTTTCTGTGCTGACCTTGGTAGACTCGGATACACCTGGTAA
TTCATTACTTTAGCTGGTTTCCACTTGAATGCTCTCAAGTCTGAAAAGCTCTCTAAGGAT
CTTGCTGCCCGTGGTATGCTCGCCTACGTCGAAACTGTCCAAAGAAAGGAAGAAAAGCAC
AAAGTCGACCAACTCACCCACCAAAAGTAATTATAAAAACATTTTTATCTATATAAAATA
AAAAAAAATGGCTCTGATAAGTAGGTATAAATAAAATATTCAAATAATAGAGATAGACAA
TCATATGATCTTTTAATAGCAATTTATCAATGTTTAATATATCAAAAAAAGCAATAGAAC
AAACAAAAGCATTCATTCGATCTATTAAAAAATAAAAAGAATATTTTATTTATACACCTC
TATAATAAATTGCTAATTTTATTTACTCATTCATTTATTAAAATTAATTTGTATTAAATA
GATGGTCTGGTGCTAACTACGTTGATGCTTGCCAAGCCCTTGTTCAACCCGAATCTCAAA
CCTTAGCCTCCTCCAAAGACTCTACTGAAAACTAATTCAAGCATTGA

>TTHERM_01141570(protein)
MDVEGKRLQEITAEIQKWWTNSRWENVERPYQAQDVARLRPTIPMDYPSNYQSKKMWKLL
KEAQANKGFHHTFGALDPVQVINLSKYLRTVYVSGWQCSATASTTNEPGPDFADYPANTV
PNKVDQLFKAQLLQDRIQNEQRAHLTPEQRAKTPRVDYLAPMIADADAGFGGITSTMKLI
KLFIEAGAAGIHLEDQRPGTKKCGHMSGKVVVSTREHVNRLIACRLQADIMGTDLIILAR
TDALSARLIDSNCDPVDHPFILGLCPDGKERTFPNAGLEAIKAKFTGAKVQEVTKLWLSK
CYDLSLTQAHEYARTLGFDFQFDWEALRSSEGFYSIDGCVELCAARAKQYLRYADMVWME
TPTPSLEVATKFSTLVKNNHPTKLLAYNLSPSFNWSAFNMSNAQIQSFCADLGRLGYTWQ
FITLAGFHLNALKSEKLSKDLAARGMLAYVETVQRKEEKHKVDQLTHQKWSGANYVDACQ
ALVQPESQTLASSKDSTENQFKH