Identifiers and Description

Gene Model Identifier

TTHERM_01145010

Standard Name

MRS1 (methionyl-tRNA synthetase 1)

Aliases

PreTt01416 | 253.m00041

Description

MRS1 methionine-tRNA ligase; methionyl-tRNA synthetase

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Cellular Component

• cytoplasm (IEA) | GO:0005737

Molecular Function

• aminoacyl-tRNA ligase activity (IEA) | GO:0004812
• ATP binding (IEA) | GO:0005524
• nucleotide binding (IEA) | GO:0000166

Biological Process

• translation (IEA) | GO:0006412
• tRNA aminoacylation for protein translation (IEA) | GO:0006418

Domains

• ( PF00133 ) tRNA synthetases class I (I, L, M and V)
• ( PF00412 ) LIM domain
• ( PF06519 ) TolA C-terminal
• ( PF07975 ) TFIIH C1-like domain
• ( PF09334 ) tRNA synthetases class I (M)
• ( TIGR00392 ) isoleucine--tRNA ligase
• ( TIGR00396 ) leucyl-tRNA synthetase
• ( TIGR00398 ) methionyl-tRNA synthetase
• ( TIGR00422 ) valyl-tRNA synthetase

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Stentor Coeruleus	SteCoe_6427	0
	Description: None
WormBase	WBGene00003415	9.997093137033517e-262
	Description: locus:mars-1 status:Partially_confirmed UniProt:D3YT55 protein_id:CBK19452.1
Tetrahymena borealis	EI9_19320.1	9.997093137033517e-262
	Description: methionyl-tRNA synthetase (838 aa)
DictyBase	DDB_G0279113	9.997093137033517e-262
	Description: metS on chromosome: 3 position 1648404 to 1650743
Oxytricha	Contig1085.1.g65	9.997093137033517e-262
	Description: tRNA synthetases class I (M)
SGD	YGR264C	9.997093137033517e-262
	Description: MES1 Methionyl-tRNA synthetase, forms a complex with glutamyl-tRNA synthetase (Gus1p) and Arc1p, which increases the catalytic efficiency of both tRNA synthetases; also has a role in nuclear export of tRNAs
WormBase	WBGene00019986	9.997093137033517e-262
	Description: status:Confirmed UniProt:Q23030 protein_id:CCD69414.1
WormBase	WBGene00002035	9.997093137033517e-262
	Description: locus:hum-1 status:Confirmed UniProt:Q19901 protein_id:CAB00095.1

General Information

No Data fetched for General Information

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_01145010(coding)
ATGGAAGTTAAACTTAGAAAATTCACAACCAAGGGTTAAGCACTTGTTGCTTCAGCCAAC
CTTTTCCATGAGGAAAAAAAGATTACATTCTCAAGGGATGAATCTGTAGCAAATGACACT
CTTGCTGTCTAAAATTAATAAGCAATTAGCGGATGGACTGCTATTTTCTCTTATCTCCTC
TAGTTAAAGATTGATAGTCCTTTATTTGGTGATTTCTACTTTGTTTGCAACTAATTGAAG
AGTGGTAAAAGATAAGTAGAAGAAAATGCCTTAGAAAATTTGAATAAAATACTTTCTACC
AGATAATTCTTAAGCGGAGAAGAACTTGGTGAAATTGATGTTATTGCTTACACTCGTGTC
AGAGCCTTTGTTAAGGATCTTCCTTTCAGCATTAAGCGTTTTACCCATCTCCACGATTGG
TTTGTTGCTGCTTAATCAACCTTAGAAGATGCTGTTAGCAAAGCTGAAACTTTCGTTGCT
TAACCTGTTGTTAAGGAAAAGAAAGCTGCTGGAAAAAAACCAGAAGGCAAACCTGAAAAA
CCAGAAAAGGCTGAAAAAACTGAAAATCCTAAAAAGGCTGAAAAAACAGAAAAAGCTGAA
AACCCTAAGAAGGCTGAAAAGGCTGAGAAAAAGGAAGCCAAAAAAGAAAAGGCTGAAAAA
CCTGCTGCTACTGAAGCTCCTAAAAAGGCTCCTGCTAAAGTTGATACTATCGATCCTGCT
TATAAGGAAAAAATTAACAATATTAGATTCGTTAGAAGCAATAAGGGTGAACCCGTTTTA
CCAGTAGATGGTTAAAGAAACATTTTGATCACCTCTGCTCTTCCTTACGTCAATAACGCT
CCTCACTTGGGTACATTGATTGGATGTGTCTTGAGTGGTGATGTTTTTGCTAGATATTGC
AGATCTAGAGGTTATAATACAATTTACATTTGTGGTACTGATGAATACGGTACTGCCACT
GAAATGAAGGCTCTTCAAGAAAAGACTACTCCTGCTGAAATTTGTACTAAGTACTATAAG
ATTTAAAAGGATGTCTATGATTGGTTTGATATCGATTTTGATATTTTCGGAAGAACCACT
ACTGAAAAGCACACCAAGATTTCTCAAGATATTTTCTTAACTCTTCATAAGAATGGTTAC
ATCAAGGAAGACATCATGCACCAAAGTTTCTGTGCTGCTTGTGATAAATTCTTAGCAGAC
AGATACGTTAACGGTACTTGCCCCTTCTGCTAACACGATGATTGCCACGGTGATTAATGT
GATAAGTGTGGTAAACTCGTTAATCCTGCCGAACTCATCAATCCTAAATGTACAATTTGC
AAGAATCCTTCTGTTATTAAAGAAACTAAGCACTGCTTCCTCGATTTACCTCAACTTGAA
AAAGAAATCGACGAATTCATTGAAAAGAGATCAAAGGAAGGAGATTGGAGTGATAACGCA
TATAAAACATCCAAGGCTTGGATTAAGAATGGTTTAAAATATAGATGCATTACTAGAGAT
TTAAAATGGGGTACTCCTATTCCTCTTGCTGGTTGGGAAAACAAGGTTATGTACGTATGG
TTCGATGCTCCTATTGGTTATCCTTCCATTACTGCTAATTTGGTTGAAGACTGGGAAAAA
TGGTGGAAAAACCCTGAAAATGTTAAACTTTATCAATTCATCGGTAAGGACAATATTCCT
TTCCACTGTGTCATCTTCCCTGGTACTCTCTTGGGAACTCGTGAAAACTGGACACTACTC
AACTCTATGTCATCTTGTGAATATCTTTAATACGAATCTGGTAAATTCTCTAAGAGTAAA
TGCGTTGGTGTATTTGGTGATGACGCCTAAAAGACTGGCATTCCCGTTGAAGTTTGGAGA
TATTACCTTTTGATTAACAGACCTGAATAAAACGATACTAATTTCTAATGGAGTGACTTT
GCTGCTAAGAATAACAACGAACTTCTTCCTAACGTTGGTAACCTTGTTCAACGTATTTTG
AAATTCCTCTACTCTAAGTTAGAAAAGAAAGTACCTACTTTAGATTTCAGTCTATTGAAC
GAAGAAGATAAGAACTGGTTAGCTTCTATTTGGAATTTGTTCCAACAATATCTTTCTCAT
ATGGAAAAGGTAGAACTCAAGAGTGCTCTTAAGGTTGTTATGTAAATTTCTTCTGAAGGT
AATAATTATATGCAAAAGAATGAACCTTGGAACAAGGCCAACCAAGAAACTGGTAGACAC
ATTGTCTCATTGTTCGTTTTGGTCAACATCATTAGATTCCTCTCTGCCTTATTCGAACCT
TTCATGCCTACTCTCAGTGCTAAAATTAATTTCATGTTGGGTTACGAAGCCAGAACCGCT
AAAGATGAAAAGATCCTTGAATTTATCAGTTCTCAACCTGATGCTATCTCTGGTCTCCTT
TCTCTTGTTCCTGGTGGATAAATCTTAAATGAACCCATTCCTATTTTCAGAAAATTGGAA
GATGATGAAATTGAAAACTTCAAGTTATAATTCAGCGGTGGAAAGAAATTGTGA

>TTHERM_01145010(gene)
ATGGAAGTTAAACTTAGAAAATTCACAACCAAGGGTTAAGCACTTGTTGCTTCAGCCAAC
CTTTTCCATGAGGAAAAAAAGATTACATTCTCAAGGGATGAATGTAAGAACAAAATATAA
TAATTCGTTTTTCATTCATTTGAAGAATCAAACATTTAATATAATAAACAATAAATAATT
TTTTTTCTATAATTTAATAAAGCTGTAGCAAATGACACTCTTGCTGTCTAAAATTAATAA
GCAATTAGCGGATGGACTGCTATTTTCTCTTATCTCCTCTAGTTAAAGATTGATAGTCCT
TTATTTGGTGATTTCTACTTTGTTTGCAACTAATTGAAGGTATTTATTACTTACTTTCCA
CTAAATAATTAAATATTTTATTCAACTATTTTATATTAAACTTATTAGAGTGGTAAAAGA
TAAGTAGAAGAAAATGCCTTAGAAAATTTGAATAAAATACTTTCTACCAGATAATTCTTA
AGCGGAGTAAATTATTTATCTATTTTTTACTTTTTTCACAAGGAGAAAATATCATTTCTA
AATTAATTAAAAATGAAAATTTCTATCAAATAGCTTAGATTAATATAAAATTATTTTAAT
ATTTTTAGGAAGAACTTGGTGAAATTGATGTTATTGCTTACACTCGTGTCAGAGCCTTTG
TTAAGGATCTTCCTTTCAGCATTAAGCGTTTTACCCATCTCCACGATTGGTTTGTTGCTG
CTTAATCAACCTTAGAAGATGCTGTTAGCAAAGCTGAAACTTTCGTTGCTTAACCTGTTG
TTAAGGAAAAGAAAGCTGCTGGAAAAAAACCAGAAGGCAAACCTGAAAAACCAGAAAAGG
CTGAAAAAACTGAAAATCCTAAAAAGGCTGAAAAAACAGAAAAAGCTGAAAACCCTAAGA
AGGCTGAAAAGGCTGAGAAAAAGGAAGCCAAAAAAGAAAAGGCTGAAAAACCTGCTGCTA
CTGAAGCTCCTAAAAAGGTAAACAATCTTTCTTAAAATATAGAATTAAAATTAGCAAAAT
ATTAAAATACCTTAATTCAACATATAAGTTTAATATATTACTAATAATTAATTTACCAAC
TTACTTAATATATAAATAAAAGGCTCCTGCTAAAGTTGATACTATCGATCCTGCTTATAA
GGAAAAAATTAACAATATTAGATTCGTTAGAAGCAATAAGGGTGAACCCGTTTTACCAGT
AGATGGTTAAAGAAACATTTTGATCACCTCTGCTCTTCCTTACGTCAATAACGCTCCTCA
CTTGGGTACATTGATTGGATGTGTCTTGAGTGGTGATGTTTTTGCTAGATATTGCAGATC
TAGAGGTTATAATACAATTTACATTTGTGGTACTGATGAATACGGTACTGCCACTGAAAT
GAAGGCTCTTCAAGAAAAGACTACTCCTGCTGAAATTTGTACTAAGTACTATAAGATTTA
AAAGGATGTCTATGATTGGTTTGATATCGATTTTGATATTTTCGGAAGAACCACTACTGA
AAAGCACACCAAGATTTCTCAAGATATTTTCTTAACTCTTCATAAGAATGGTTACATCAA
GGAAGACATCATGCACCAAAGTTTCTGTGCTGCTTGTGATAAATTCTTAGCAGACAGATA
CGTTAACGGTACTTGCCCCTTCTGCTAACACGATGATTGCCACGGTGATTAATGTGATAA
GTGTGGTAAACTCGTTAATCCTGCCGAACTCATCAATCCTAAATGTACAATTTGCAAGAA
TCCTTCTGTTATTAAAGAAACTAAGCACTGCTTCCTCGATTTACCTCAACTTGAAAAAGA
AATCGACGAATTCATTGAAAAGTAAACACAACACTAAATTATTTCAACAATATTTTAAAG
TAATTTTTAATAAAATAAATTTTAGGAGATCAAAGGAAGGAGATTGGAGTGATAACGCAT
ATAAAACATCCAAGGCTTGGATTAAGAATGGTTTAAAATATAGATGCATTACTAGAGATT
TAAAATGGGGTACTCCTATTCCTCTTGCTGGTTGGGAAAACAAGGTTATGTACGTATGGT
TCGATGCTCCTATTGGTTATCCTTCCATTACTGCTAATTTGGTTGAAGACTGGGAAAAAT
GGTGGAAAAACCCTGAAAATGTTAAACTTTATCAATTCATCGGTAAGGACAATATTCCTT
TCCACTGTGTCATCTTCCCTGGTACTCTCTTGGGAACTCGTGAAAACTGGACACTACTCA
ACTCTATGTCATCTTGTGAATATCTTTAATACGAATCTGGTAAATTCTCTAAGAGTAAAT
GCGTTGGTGTATTTGGTGATGACGCCTAAAAGACTGGCATTCCCGTTGAAGTTTGGAGAT
ATTACCTTTTGATTAACAGACCTGAATAAAACGATACTAATTTCTAATGGAGTGACTTTG
CTGCTAAGAATAACAACGAACTTCTTCCTAACGTTGGTAACCTTGTTCAACGTATTTTGA
AATTCCTCTACTCTAAGTTAGAAAAGGTAAATTAGTGTTTAAATTTTATTAATTATCATT
CTAAACTTGCATTTTTTATGAACAGAAAGTACCTACTTTAGATTTCAGTCTATTGAACGA
AGAAGATAAGAACTGGTTAGCTTCTATTTGGAATTTGTTCCAACAATATCTTTCTCATAT
GGAAAAGGTAGAACTCAAGAGTGCTCTTAAGGTTGTTATGTAAATTTCTTCTGAAGGTAA
TAATTATATGCAAAAGAATGAACCTTGGAACAAGGCCAACCAAGAAACTGGTAGACACAT
TGTCTCATTGTTCGTTTTGGTCAACATCATTAGATTCCTCTCTGCCTTATTCGAACCTTT
CATGCCTACTCTCAGTGCTAAAATTAATTTCATGTTGGGTTACGAAGCCAGAACCGCTAA
AGATGAAAAGATCCTTGAATTTATCAGTTCTCAACCTGATGCTATCTCTGGTCTCCTTTC
TCTTGTTCCTGGTGGATAAATCTTAAATGAACCCATTCCTATTTTCAGAAAATGTAAATA
AATTTTGTAAAAGTAATAAGAAATTATTAAAAAACATTAATTAAAAAAATAGTGGAAGAT
GATGAAATTGAAAACTTCAAGTTATAATTCAGCGGTGGAAAGAAATTGTGA

>TTHERM_01145010(protein)
MEVKLRKFTTKGQALVASANLFHEEKKITFSRDESVANDTLAVQNQQAISGWTAIFSYLL
QLKIDSPLFGDFYFVCNQLKSGKRQVEENALENLNKILSTRQFLSGEELGEIDVIAYTRV
RAFVKDLPFSIKRFTHLHDWFVAAQSTLEDAVSKAETFVAQPVVKEKKAAGKKPEGKPEK
PEKAEKTENPKKAEKTEKAENPKKAEKAEKKEAKKEKAEKPAATEAPKKAPAKVDTIDPA
YKEKINNIRFVRSNKGEPVLPVDGQRNILITSALPYVNNAPHLGTLIGCVLSGDVFARYC
RSRGYNTIYICGTDEYGTATEMKALQEKTTPAEICTKYYKIQKDVYDWFDIDFDIFGRTT
TEKHTKISQDIFLTLHKNGYIKEDIMHQSFCAACDKFLADRYVNGTCPFCQHDDCHGDQC
DKCGKLVNPAELINPKCTICKNPSVIKETKHCFLDLPQLEKEIDEFIEKRSKEGDWSDNA
YKTSKAWIKNGLKYRCITRDLKWGTPIPLAGWENKVMYVWFDAPIGYPSITANLVEDWEK
WWKNPENVKLYQFIGKDNIPFHCVIFPGTLLGTRENWTLLNSMSSCEYLQYESGKFSKSK
CVGVFGDDAQKTGIPVEVWRYYLLINRPEQNDTNFQWSDFAAKNNNELLPNVGNLVQRIL
KFLYSKLEKKVPTLDFSLLNEEDKNWLASIWNLFQQYLSHMEKVELKSALKVVMQISSEG
NNYMQKNEPWNKANQETGRHIVSLFVLVNIIRFLSALFEPFMPTLSAKINFMLGYEARTA
KDEKILEFISSQPDAISGLLSLVPGGQILNEPIPIFRKLEDDEIENFKLQFSGGKKL