Identifiers and Description

Gene Model Identifier

TTHERM_01205300

Standard Name

PYK4 (PYruvate Kinase)

Aliases

PreTt02720 | 273.m00025

Description

PYK4 pyruvate kinase complex alpha subunit; Pyruvate kinase- barrel domain containing protein

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Molecular Function

• magnesium ion binding (IEA) | GO:0000287
• potassium ion binding (IEA) | GO:0030955
• pyruvate kinase activity (IEA) | GO:0004743

Biological Process

• glycolytic process (IEA) | GO:0006096

Domains

• ( PF00224 ) Pyruvate kinase, barrel domain
• ( PF02887 ) Pyruvate kinase, alpha/beta domain
• ( TIGR01064 ) pyruvate kinase

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Tetrahymena borealis	EI9_20555.1	9.997093137033517e-262
	Description: pyruvate kinase, barrel domain-containing protein (805 aa)
Oxytricha	Contig21940.0.g53	5.002115178225629e-63
	Description: Pyruvate kinase, barrel domain
DictyBase	DDB_G0283247	3.999543040313994e-55
	Description: pyk on chromosome: 4 position 344914 to 346711
WormBase	WBGene00014001	5.000680012816624e-42
	Description: locus:pyk-2 Pyruvate kinase status:Confirmed UniProt:D3YT37 protein_id:CBK19521.1
WormBase	WBGene00000244	5.000680012816624e-42
	Description: locus:bbs-8 status:Partially_confirmed UniProt:Q23049 protein_id:CCD74239.1
SGD	YAL038W	1.9993430003514377e-39
	Description: CDC19 Pyruvate kinase, functions as a homotetramer in glycolysis to convert phosphoenolpyruvate to pyruvate, the input for aerobic (TCA cycle) or anaerobic (glucose fermentation) respiration
Stentor Coeruleus	SteCoe_2266	3.873997628687187e-21
	Description: None

General Information

No Data fetched for General Information

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_01205300(coding)
ATGAGTAATAATAGCCCAGATAAAATATAGAACTCTTAATAAGGCGTAAACGATGACAGA
ATGGAATTTAGACATGGATAATTTGATTAAAATAACAATCATCATTCTGAGGACCAATGT
ACCTAGTAGTCTCATTATTAAGATGAAACTTCAATGAGCAATCATCAAGAAGAAAACCAA
GTTAGCCAATAAAAATATTAATAGAATTCTCCTAATCAAAAATCAGAACATTCTATGACA
CTTCCTTCTTTAGATACTCCTCTTCTTTAATTTACGAATCAGTAAGCACAAGGAAAATCT
TTACTATTTCATGAGTCAGATGATCCATTTCATTCTGAAAACCATACTCCAATTGCCATC
CATTAAAATCAACATCAAAAATCACATCACTTAATTGATAAAAAAAGGACAGTATTAAAT
TTCGTGAAATCAAGAGGAGAATTGCTGGAATATGAAAGTGAATATTATGAAAATTTGAGA
TAAAAAATTATTAGAAAGCGCAGGACAAAGATAATTGCAACTATTAATTAAAATAATTAT
AAGACATATGATTAAGTTAGAGATCTTTATTTAGCAGGTGTCAATTCATTTTTAATTAAT
ATGGCTTACTGCGAAAGATAGTTTTTAGCGCAATTATGTTAATGGAGAGATTAATTAGAA
AAAGAATATAATGTTCACATTCCACTCACTTGTGTTTTAAAAGGAAGTTTAGTTCGGATA
GGCTAACTATCATAACCTGAAACTTATTTAAGAAAGGGACAATAATTTAGAATAATTATT
AAGAAGAAGATAGTTGGTGATTCTAATATCTGTTCTGTAGACGATGATAATTTGATTAAA
AGAATAGGTGTAGGTGCTAAAATTATCATTGACTATGGTCAAGTAGGATTAACAGTTATA
AAAAAAGAAAAGAGTGATGAAACACTTAAATATTTATAAGAAAACTTTGGATATGGACAT
TAATTTACCCGCCCAATGACTGAAAAGTAAAAACGCACAGATAATTTTGTCAACACATCT
TCTGCCTCAGACGCTGACAGTTCTTCTAAGAAGAGAATGTCTGAATCACTGATAAAATAA
GTTAATTAGAAGAGTATTCCAAGGCAATCTGTTTAAGTTTTACCATATTCAACAAATATA
ATTTAAACAAATGAATATGAACAATCTGCTGATAATAGCGTAATCTCATCAAATACTACA
ACACCTTCAACTAGGAATGTATTTGCAGATTAATTAAAACAACTTAAAAAGAATACAAAC
TAAAAACTATATGATGTGATAGTTTGCACTGTTGATAGTGATTGCATGTTGAAATCTTAC
AAACCTATTTTCATTTATAAAAGTAGAGACGAAAAAGAAACATTATTTTACACTAAGTAA
AGTAAGTAGAGTAAATAATTAAATAAAAACCATTAATTTACAGATGAAAAAGATTCTAAT
GGTGAAGAATAAGATTTTGATGATGAGGAATATGATGAATTCAGTGAAAATGTCATAAGT
GCAAAAGATATCACTGATATTACAAATGCTCTTAATCATGACATTGATAGTGTATGTGTA
TCAAATGTAAGAACAGCAGAAGATATCAGAGTTGTCAAAAGGCATTGTCAGTCAAAATAG
ACAAAAATTATTGCTAAAATTTAAACTTTAGAAGGTGTATAAAATTATGATGAAATTTTA
AAGGTTTCTGATGCTGTATTGATAGCTAGAGGGTATTTAACAGTTCACATACCTGTTGAA
AAGCTTCACTTTAAATAGAAAGAACTTATTTAAAAATCAAATGAAAGCTTAAAGCCTGTT
TTAGTGTCATGTAACATATTAGATTCCATGGTTTCTTCATTGCTTCCTACTACTTGTGAA
GTAGGAGAAATATCTAATCTTGTATCAGACTATGTAGATGCTATTATTTTAAGCGGCGAA
ACAAGCTATGGAATGTATCCTATTCAAGCTGTTGAAACTCTTTCTCGTATTTGTATGGAG
ACAGAAGCAAGATAAATTTTAAAAAATTTAAATGACACGACTCGTCCAATTTAAATATAG
TGGTCAAAACAATCTGTAATAAATTCAATAGTTAAATGCACTCTTGATGCTGCCTATAAT
ATATAAGCAAATCTTATTATTGTATTTACAAGTACTGGAAGCACTGCTCTCAAAGTTTCA
AAATTAAGACCTCCATGTCCTATAATAGCTGTCACATCGAACCATAAAGTTGCAAGACAT
ATAAATTATTTATCATCAGTTACTGGTAAGGTATTCTTTACCCTTGTAGGAACTAATGTA
CTTACAGAAAAGGTGTTAGAATACGCTAAAGATTAAAAGTATGTTAAATCAGGTGATTAT
GTTATAATCACTTCTGGTGAAATAGAAAATTTATCTGGAATGACAAATAATCTAAAAATT
GTTTAAGTATAGTGA

>TTHERM_01205300(gene)
ATGAGTAATAATAGCCCAGATAAAATATAGAACTCTTAATAAGGCGTAAACGATGACAGA
ATGGAATTTAGACATGGATAATTTGATTAAAATAACAATCATCATTCTGAGGACCAATGT
ACCTAGTAGTCTCATTATTAAGATGAAACTTCAATGAGCAATCATCAAGAAGAAAACCAA
GTTAGCCAATAAAAATATTAATAGAATTCTCCTAATCAAAAATCAGAACATTCTATGACA
CTTCCTTCTTTAGATACTCCTCTTCTTTAATTTACGAATCAGTAAGCACAAGGAAAATCT
TTACTATTTCATGAGTCAGATGATCCATTTCATTCTGAAAACCATACTCCAATTGCCATC
CATTAAAATCAACATCAAAAATCACATCACTTAATTGATAAAAAAAGGACAGTATTAAAT
TTCGTGAAATCAAGAGGAGAATTGCTGGAATATGAAAGTGAATATTATGAAAATTTGAGA
TAAAAAATTATTAGAAAGCGCAGGACAAAGATAATTGCAACTATTAATTAAAATAATTAT
AAGACATATGATTAAGTTAGAGATCTTTATTTAGCAGGTGTCAATTCATTTTTAATTAAT
ATGGCTTACTGCGAAAGATAGTTTTTAGCGCAATTATGTTAATGGAGAGATTAATTAGAA
AAAGAATATAATGTTCACATTCCACTCACTTGTGTTTTAAAAGGAAGTTTAGTTCGGATA
GGCTAACTATCATAACCTGAAACTTATTTAAGAAAGGTAAAAATACTTACAAAATTAATA
ATATTAAAAAAGACATTATTAAGCTATAATTAAAATACAAAAAATAGTTTATTTTAAAAA
GCAAGCGTTTTAACCTTAAAAATAAATTTAAATAATAGCTAATAATGAAGTGAGTTCATC
CATGAATAGCTTTATTAACTATTCATTTTTAAAATATTAGGGACAATAATTTAGAATAAT
TATTAAGAAGAAGATAGTTGGTGATTCTAATATCTGTTCTGTAGACGATGATAATTTGAT
TAAAAGAATAGGTGTAGGTGCTAAAATTATCATTGACTATGGTCAAGTAGGATTAACAGT
TATAAAAAAAGAAAAGAGTGATGAAACACTTAAATATTTATAAGAAAACTTTGGATATGG
ACATTAATTTACCCGCCCAATGACTGAAAAGTAAAAACGCACAGATAATTTTGTCAACAC
ATCTTCTGCCTCAGACGCTGACAGTTCTTCTAAGAAGAGAATGTCTGAATCACTGATAAA
ATAAGTTAATTAGAAGAGTATTCCAAGGCAATCTGTTTAAGTTTTACCATATTCAACAAA
TATAATTTAAACAAATGAATATGAACAATCTGCTGATAATAGCGTAATCTCATCAAATAC
TACAACACCTTCAACTAGGAATGTATTTGCAGATTAATTAAAACAACTTAAAAAGAATAC
AAACTAAAAACTATATGATGTGATAGTTTGCACTGTTGATAGTGATTGCATGTTGAAATC
TTACAAACCTATTTTCATTTATAAAAGTAGAGACGAAAAAGAAACATTATTTTACACTAA
GTAAAGTAAGTAGAGTAAATAATTAAATAAAAACCATTAATTTACAGATGAAAAAGATTC
TAATGGTGAAGAATAAGATTTTGATGATGAGGAATATGATGAATTCAGTGAAAATGTCAT
AAGTGCAAAAGATATCACTGATATTACAAATGCTCTTAATCATGACATTGATAGTGTATG
TGTATCAAATGTAAGAACAGCAGAAGATATCAGAGTTGTCAAAAGGCATTGTCAGTCAAA
ATAGACAAAAATTATTGCTAAAATTTAAACTTTAGAAGGTAACTAACTAACTAACCAAAT
AGCTTTTTAAATTTTATATATATAATTTTAATTAAAATTAGGTGTATAAAATTATGATGA
AATTTTAAAGGTTTCTGATGCTGTATTGATAGCTAGAGGGTATTTAACAGTTCACATACC
TGTTGAAAAGCTTCACTTTAAATAGAAAGAACTTATTTAAAAATCAAATGAAAGCTTAAA
GCCTGTTTTAGTGTCATGTAACATATTAGATTCCATGGTTTCTTCATTGCTTCCTACTAC
TTGTGAAGTAGGAGAAATATCTAATCTTGTATCAGACTATGTAGATGCTATTATTTTAAG
CGGCGAAACAAGCTATGGAATGTATCCTATTCAAGCTGTTGAAACTCTTTCTCGTATTTG
TATGGAGACAGAAGCAAGATAAATTTTAAAAAATTTAAATGACACGACTCGTCCAATTTA
AATATAGTGGTCAAAACAATCTGTAATAAATTCAATAGTTAAATGCACTCTTGATGCTGC
CTATAATATATAAGCAAATCTTATTATTGTATTTACAAGTACTGGAAGCACTGCTCTCAA
AGTTTCAAAATTAAGACCTCCATGTCCTATAATAGCTGTCACATCGAACCATAAAGTTGC
AAGACATATAAATTATTTATCATCAGTTACTGGTAAGGTATTCTTTACCCTTGTAGGAAC
TAATGTACTTACAGAAAAGGTGTTAGAATACGCTAAAGATTAAAAGTATGTTAAATCAGG
TGATTATGTTATAATCACTTCTGGTGAAATAGAAAATTTATCTGGAATGACAAATAATCT
AAAAATTGTTTAAGTATAGTGA

>TTHERM_01205300(protein)
MSNNSPDKIQNSQQGVNDDRMEFRHGQFDQNNNHHSEDQCTQQSHYQDETSMSNHQEENQ
VSQQKYQQNSPNQKSEHSMTLPSLDTPLLQFTNQQAQGKSLLFHESDDPFHSENHTPIAI
HQNQHQKSHHLIDKKRTVLNFVKSRGELLEYESEYYENLRQKIIRKRRTKIIATINQNNY
KTYDQVRDLYLAGVNSFLINMAYCERQFLAQLCQWRDQLEKEYNVHIPLTCVLKGSLVRI
GQLSQPETYLRKGQQFRIIIKKKIVGDSNICSVDDDNLIKRIGVGAKIIIDYGQVGLTVI
KKEKSDETLKYLQENFGYGHQFTRPMTEKQKRTDNFVNTSSASDADSSSKKRMSESLIKQ
VNQKSIPRQSVQVLPYSTNIIQTNEYEQSADNSVISSNTTTPSTRNVFADQLKQLKKNTN
QKLYDVIVCTVDSDCMLKSYKPIFIYKSRDEKETLFYTKQSKQSKQLNKNHQFTDEKDSN
GEEQDFDDEEYDEFSENVISAKDITDITNALNHDIDSVCVSNVRTAEDIRVVKRHCQSKQ
TKIIAKIQTLEGVQNYDEILKVSDAVLIARGYLTVHIPVEKLHFKQKELIQKSNESLKPV
LVSCNILDSMVSSLLPTTCEVGEISNLVSDYVDAIILSGETSYGMYPIQAVETLSRICME
TEARQILKNLNDTTRPIQIQWSKQSVINSIVKCTLDAAYNIQANLIIVFTSTGSTALKVS
KLRPPCPIIAVTSNHKVARHINYLSSVTGKVFFTLVGTNVLTEKVLEYAKDQKYVKSGDY
VIITSGEIENLSGMTNNLKIVQVQ