Identifiers and Description

Gene Model Identifier

TTHERM_01262850

Standard Name

FAP251 (Flagellar Associated Protein 251)

Aliases

PreTt01683 | 298.m00024

Description

FAP251 WD-40 protein putative; Calmodulin and spoke-associated complex (CSC) protein; required for stable assembly of radial spoke protein RS3; homolog of the Chlamydomonas CSC protein FAP251; WD repeat Echinoderm Microtubule-associated Protein-like

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Cellular Component

• radial spoke (IDA) | GO:0001534

Molecular Function

• obsolete dipeptidyl-peptidase I activity (IEA) | GO:0004214
• obsolete sodium-transporting two-sector ATPase activity (IEA) | GO:0015443
• obsolete tachykinin (IEA) | GO:0008648
• rRNA methyltransferase activity (IEA) | GO:0008649
• type 4 neuropeptide Y receptor binding (IEA) | GO:0031844

Biological Process

• cilium-dependent cell motility (IMP) | GO:0060285
• endomitotic cell cycle (IEA) | GO:0007113
• fibroblast growth factor receptor signaling pathway (IEA) | GO:0008543
• heme A biosynthetic process (IEA) | GO:0006784
• induction of apoptosis by extracellular signals (IEA) | GO:0008624
• mitotic cytokinetic cell separation (IEA) | GO:1902409
• negative regulation of PERK-mediated unfolded protein response (IEA) | GO:1903898
• nipple development (IEA) | GO:0060618
• obsolete negative regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity (IEA) | GO:1904218
• obsolete positive regulation by host of symbiont defense response (IEA) | GO:0052197
• ommochrome biosynthetic process (IEA) | GO:0006727
• plant-type cell wall modification (IEA) | GO:0009827
• propan-2-ol biosynthetic process (IEA) | GO:1902640

Domains

• ( PF00400 ) WD domain, G-beta repeat

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

No Data fetched for Homologs

General Information

No Data fetched for General Information

Associated Literature

1. Ref:25694453: Urbanska P, Song K, Joachimiak E, Krzemien-Ojak L, Koprowski P, Hennessey T, Jerka-Dziadosz M, Fabczak H, Gaertig J, Nicastro D, Wloga D (2015) The CSC proteins FAP61 and FAP251 build the basal substructures of radial spoke 3 in cilia. Molecular biology of the cell 26(8):1463-75

Sequences

>TTHERM_01262850(coding)
ATGTATTAGTAAGAAGAATACGAAGTTAACAATGAAGGCTAAGAAGATGTTAGCAAGATA
AATGCATTAAATTTGAAATGGACTTTAGGTTTTAATTTCTAGCTCACTGATGGCGTTCAC
AATTTAACAAATGAAAAAAGAAAAGAAATTTTCTATCCTGTTGCGCACACTGGTGTTATA
TACGATTATGAAAACAATACATAAAGATTATTATAGGGTCATTGTAATAGAATTACAGCA
ACAGCATATTGCAAATTCTCAGATATAATTGTTACTGCTGACTGCGGTCCAGATTCTATG
TTAGTAGTCTGGGATGCATCAACAGGTATTCCTAAAAAGACTATCTTTGAACCACATCCT
AATGGTTGTTAAGCTTTAGATATTTCTCAAGATGGACAATTCATCGTGACTCTTTCAAAA
GAAGCTAATACAGATACTGATGTATAATCTCTTTCTTTGTGGGAGTGGAATAAAGATGAT
GAACCATGTTTGATTACCAATGAATTCGATAGAAGAATTAAGGATTATTAATATTTCGTT
AGATTCAATTCAGATGATAACACTGAATTTGCAACAACTGGTAAGACAAGAATTGTTTTT
TGGAGAAGAGAAGGAGAATAAAAAGGTTTTAACTATTATTCCCCTGGTAACATTCCATCT
CTTAAGGTTCTCACTCAAACAGTATTTATACCTGATAATACATAGGTTGTTACAGGAACA
ACTGATGGTCATATTATTGTATGGGATATTTCTCTTATCATAGAAAAAGTAGACACTCCA
AAAGAAAGAAGAGCAATTAAATTGGTTGATCTTATGAATAAATCAAAAAAGCCTGATGGC
AAAAAAGGATCAAATTCAATTAATATATTAAAAATTTAAGATAACTATTTAGTTATTGGT
TCATCTAATGGATCTATCCGTTTTTATGACTTTCAATACAGAATTATAGCTTGGTTTGAA
GATGCAATTATAGGCTCTATCAGCAATATTTCTTTTGCAAATACTCCAATGATTGAAGAC
AATGAAGATGAAGATGGCTTTGATGATGAAAGAAAAGATAAGGGTGAAAATGAACCTAAA
TTTATCTGCCCTGACTTTATTGTAGTAGATCTTGATGCAACTATCACTATGTTAAATTAC
AAACTTTTTGAAGAATTAGATGATGAAAAGAAAAAGGGAACTACTTTAATGAAATCTATA
GTTTCACCAATTATTGCAATGAGTTGTAGACCAAACTCTAATGTTATTGGTATTTGTTGT
GAAAATGGTTATCTTTATGAATGGAATTTCTAAGAAAAATCTTCCGTTCTATCTATTTTA
AGAGTATTTGATACAGATAAAGAAAATATTCCTAATTGCATTGATTACTCTCCAGATGGA
AATTGGCTCTCTGTAGCCACTAAGTCTGGTAAAATCCATATATTCGATTGCAAAGAAAAA
TAATGGCAAAACTCAGTTCTTGAAGTATCTGAAAATGAATAAGGAAAACCCAAAGTTAAT
ATGCAGGTATTTTCTTCAGACTCAAAAAATCTAGCTACTATGGATGCTGATTATGCTGTT
TCACTCTTTACTATTGATCATAGATAATTTGATGTGAATATTCCAGAAAAGGAATGGTAA
TTCGTTGGAAAGCATAGAATCCATCATAGTGAAATTAAATCTATAGCATTTGGCGAGTCA
AAAAATGAAAACGATAAAAAATATTATAGATTATTTAGTATTGGAGCAGATATGAAAATG
GTAGAATATGAAGTTCTTGAAATCGACTATAGCAAGCAAAAAGAAAAAGGATAATAAATA
AATTATATTGACAGACTAAAGCTTAAATCCATATATCCAATTGAATAAGAAACAATACCT
ACTGCATGTATCTGGTACCCTATAAATATGTATAAAGAAGATGTCCTGCTTACAGTCAAT
GAAGAATTCAAAATAAAATTGTGGCAATTTATGAAGGACAATTTCAAATTTTGTAAAAAG
ACATGTCTTGGTCCAATTTATGGTGGCGCAATAAATAAATTACTAATTTTAAATTAAAAC
GATGCTTAAAATGATTATTAAGATAAATACCTTGCTTATTCAACTAAAGAAAAAGTAGTA
GGAATTATTAAGCTTCCTTTAGAAGGTAATCCTAATTAAACTATGGGTTTAATTGCTCAC
CCTGATAAAATTACTAGTATTAGTTGCTCTAATGATGGTAAACACTTCTTTTCATCAGGT
TCAGATGATTATTGTGTTAATGTATGGTCTGTCAATGTGTAGGCTTTAGAATAAATATTT
GCAACCAATCCAAATGAAGACCCATATCCAAAACTTCTTGAAGGTGGAGAAGATGGATAA
ACACATTAAGACTTAAAGAATTTCTTCTATTATTCTTAGATTAGAAGTAAGGATGAGCAT
ACAACAAAAGCAAGAAAGCTAGATGGTAAAGTGCCATTAATTGCCATTCCAGATATGATG
AGGTCTATGGGTTACTATCCTACTAATAAGGAAATAGAAAATATGTAAAACGAAATTAGA
TTCTCTAAATATCTTGATCCTGGCGAGTAGGTAGAAGAATTAGACTTAAACATGTTCTTG
AAATTATTCGTCAATCACAGACCTGTATAAGGTATTGGTAAATCAAAAATTGCTGAGTCA
CTTAATACTTTAACTAAAAGTTTGAGTGATTCTGCTAAGGAAATTGCTGAATAGGCTAAA
GGTTAATCTGTATAACCTAAAACATATAATATTGATGGCATTGGAGAGATTTCTTTATAA
GACTTAAAAAAAATATTAACCACTGAAGGAGAGCGTATGACTAATGAAGAATTTGATGGT
AATTTATAATATTTTAAATGA

>TTHERM_01262850(gene)
TCTTTTTACTATCAAAATAAATATCAATTATTCATTCAAGATAAACAAAAAATTTAAAAT
CAATTTGTAAAATATATTCAAATTATCTAAAGCTAATTGATTGAAATAAATAGTAAGGCG
AATAAATGTATTAGTAAGAAGAATACGAAGTTAACAATGAAGGCTAAGAAGATGTTAGCA
AGATAAATGCATTAAATTTGAAATGGACTTTAGGTTTTAATTTCTAGCTCACTGATGGCG
TTCACAATTTAACAAATGAAAAAAGAAAAGAAATTTTCTATCCTGTTGCGCACACTGGTG
TTATATACGATTATGAAAACAATACATAAAGATTATTATAGGGTCATTGTAATAGAATTA
CAGCAACAGCATATTGCAAATTCTCAGATATAATTGTTACTGCTGACTGCGGTCCAGATT
CTATGTTAGTAGTCTGGGATGCATCAACAGGTATTCCTAAAAAGACTATCTTTGAACCAC
ATCCTAATGGTTGTTAAGCTTTAGATATTTCTCAAGATGGACAATTCATCGTGACTCTTT
CAAAAGAAGCTAATACAGATACTGATGTATAATCTCTTTCTTTGTGGGAGTGGAATAAAG
ATGATGAACCATGTTTGATTACCAATGAATTCGATAGAAGAATTAAGGATTATTAATATT
TCGTTAGATTCAATTCAGATGATAACACTGAATTTGCAACAACTGGTAAGACAAGAATTG
TTTTTTGGAGAAGAGAAGGAGAATAAAAAGGTTTTAACTATTATTCCCCTGGTAACATTC
CATCTCTTAAGGTTCTCACTCAAACAGTATTTATACCTGATAATACATAGGTTGTTACAG
GAACAACTGATGGTCATATTATTGTATGGGATATTTCTCTTATCATAGAAAAAGTAGACA
CTCCAAAAGAAAGAAGAGCAATTAAATTGGTTGATCTTATGAATAAATCAAAAAAGCCTG
ATGGCAAAAAAGGATCAAATTCAATTAATATATTAAAAATTTAAGATAACTATTTAGTTA
TTGGTTCATCTAATGGATCTATCCGTTTTTATGACTTTCAATACAGAATTATAGCTTGGT
TTGAAGATGCAATTATAGGCTCTATCAGCAATATTTCTTTTGCAAATACTCCAATGATTG
AAGACAATGAAGATGAAGATGGCTTTGATGATGAAAGAAAAGATAAGGGTGAAAATGAAC
CTAAATTTATCTGCCCTGACTTTATTGTAGTAGATCTTGATGCAACTATCACTATGTTAA
ATTACAAACTTTTTGAAGAATTAGATGATGAAAAGAAAAAGGGAACTACTTTAATGAAAT
CTATAGTTTCACCAATTATTGCAATGAGTTGTAGACCAAACTCTAATGTTATTGGTATTT
GTTGTGAAAATGGTTATCTTTATGAATGGAATTTCTAAGAAAAATCTTCCGTTCTATCTA
TTTTAAGAGTATTTGATACAGATAAAGAAAATATTCCTAATTGCATTGATTACTCTCCAG
ATGGAAATTGGCTCTCTGTAGCCACTAAGTCTGGTAAAATCCATATATTCGATTGCAAAG
AAAAATAATGGCAAAACTCAGTTCTTGAAGTATCTGAAAATGAATAAGGAAAACCCAAAG
TTAATATGCAGGTATTTTCTTCAGACTCAAAAAATCTAGCTACTATGGATGCTGATTATG
CTGTTTCACTCTTTACTATTGATCATAGATAATTTGATGTGAATATTCCAGAAAAGGAAT
GGTAATTCGTTGGAAAGCATAGAATCCATCATAGTGAAATTAAATCTATAGCATTTGGCG
AGTCAAAAAATGAAAACGATAAAAAATATTATAGATTATTTAGTATTGGAGCAGATATGA
AAATGGTAGAATATGAAGTTCTTGAAATCGACTATAGCAAGCAAAAAGAAAAAGGATAAT
AAATAAATTATATTGACAGACTAAAGCTTAAATCCATATATCCAATTGAATAAGAAACAA
TACCTACTGCATGTATCTGGTACCCTATAAATATGTATAAAGAAGATGTCCTGCTTACAG
TCAATGAAGAATTCAAAATAAAATTGTGGCAATTTATGAAGGACAATTTCAAATTTTGTA
AAAAGACATGTCTTGGTCCAATTTATGGTGGCGCAATAAATAAATTACTAATTTTAAATT
AAAACGATGCTTAAAATGATTATTAAGATAAATACCTTGCTTATTCAACTAAAGAAAAAG
TAGTAGGAATTATTAAGCTTCCTTTAGAAGGTAATCCTAATTAAACTATGGGTTTAATTG
CTCACCCTGATAAAATTACTAGTATTAGTTGCTCTAATGATGGTAAACACTTCTTTTCAT
CAGGTTCAGATGATTATTGTGTTAATGTATGGTCTGTCAATGTGTAGGCTTTAGAATAAA
TATTTGCAACCAATCCAAATGAAGACCCATATCCAAAACTTCTTGAAGGTGGAGAAGATG
GATAAACACATTAAGACTTAAAGAATTTCTTCTATTATTCTTAGATTAGAAGTAAGGATG
AGCATACAACAAAAGCAAGAAAGCTAGATGGTAAAGTGCCATTAATTGCCATTCCAGATA
TGATGAGGTCTATGGGTTACTATCCTACTAATAAGGAAATAGAAAATATGTAAAACGAAA
TTAGATTCTCTAAATATCTTGATCCTGGCGAGTAGGTAGAAGAATTAGACTTAAACATGT
TCTTGAAATTATTCGTCAATCACAGACCTGTATAAGGTATTGGTAAATCAAAAATTGCTG
AGTCACTTAATACTTTAACTAAAAGTTTGAGTGATTCTGCTAAGGAAATTGCTGAATAGG
CTAAAGGTTAATCTGTATAACCTAAAACATATAATATTGATGGCATTGGAGAGATTTCTT
TATAAGACTTAAAAAAAATATTAACCACTGAAGGAGAGCGTATGACTAATGAAGAATTTG
ATGGTAATTTATAATATTTTAAATGAAATATTAAATAAAATTAAAAATAGAATGTCTCAA
AATATTATGTGGTGAAAATGAAGACTAAATTCCTCAATAAATTAATGTAAACAATTTATG
TGAAGATATTTTAGGTTTTGAAGATTTAGAAGGTGAAGAAAGAGATGATAACATTGAAGA
TTAGTATGAAGATGAAGAAAATGAAGAATATGATTAAGATTGAATTTATTTTACCAATTT
TTATATTACTAATTAAAATTAAGAAAATAATTTAGATTTGTAAATAATCTTTAAGTTTAT
TTTATAAGTAAGTTGCTTACTTGCTTGCATC

>TTHERM_01262850(protein)
MYQQEEYEVNNEGQEDVSKINALNLKWTLGFNFQLTDGVHNLTNEKRKEIFYPVAHTGVI
YDYENNTQRLLQGHCNRITATAYCKFSDIIVTADCGPDSMLVVWDASTGIPKKTIFEPHP
NGCQALDISQDGQFIVTLSKEANTDTDVQSLSLWEWNKDDEPCLITNEFDRRIKDYQYFV
RFNSDDNTEFATTGKTRIVFWRREGEQKGFNYYSPGNIPSLKVLTQTVFIPDNTQVVTGT
TDGHIIVWDISLIIEKVDTPKERRAIKLVDLMNKSKKPDGKKGSNSINILKIQDNYLVIG
SSNGSIRFYDFQYRIIAWFEDAIIGSISNISFANTPMIEDNEDEDGFDDERKDKGENEPK
FICPDFIVVDLDATITMLNYKLFEELDDEKKKGTTLMKSIVSPIIAMSCRPNSNVIGICC
ENGYLYEWNFQEKSSVLSILRVFDTDKENIPNCIDYSPDGNWLSVATKSGKIHIFDCKEK
QWQNSVLEVSENEQGKPKVNMQVFSSDSKNLATMDADYAVSLFTIDHRQFDVNIPEKEWQ
FVGKHRIHHSEIKSIAFGESKNENDKKYYRLFSIGADMKMVEYEVLEIDYSKQKEKGQQI
NYIDRLKLKSIYPIEQETIPTACIWYPINMYKEDVLLTVNEEFKIKLWQFMKDNFKFCKK
TCLGPIYGGAINKLLILNQNDAQNDYQDKYLAYSTKEKVVGIIKLPLEGNPNQTMGLIAH
PDKITSISCSNDGKHFFSSGSDDYCVNVWSVNVQALEQIFATNPNEDPYPKLLEGGEDGQ
THQDLKNFFYYSQIRSKDEHTTKARKLDGKVPLIAIPDMMRSMGYYPTNKEIENMQNEIR
FSKYLDPGEQVEELDLNMFLKLFVNHRPVQGIGKSKIAESLNTLTKSLSDSAKEIAEQAK
GQSVQPKTYNIDGIGEISLQDLKKILTTEGERMTNEEFDGNLQYFK