Identifiers and Description

Gene Model Identifier

TTHERM_01299650

Standard Name

TOP1 (Topoisomerase I)

Aliases

PreTt17571 | 315.m00022

Description

TOP1 DNA topoisomerase I; Eukaryotic DNA topoisomerase I, catalytic core family protein; DNA topoisomerase IB

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

No Data fetched for Gene Ontology Annotations

Domains

• ( PF01028 ) Eukaryotic DNA topoisomerase I, catalytic core
• ( PF02919 ) Eukaryotic DNA topoisomerase I, DNA binding fragment
• ( PF14370 ) C-terminal topoisomerase domain

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

No Data fetched for Homologs

General Information

No Data fetched for General Information

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_01299650(coding)
ATGAGTAGCAAGAAGAACACTAAGAAAGTCTCTGATAGCGAGGACGATGATTTTGAAGAG
GAAGAAGATGAATCAGAAGGTTCAGGAGAGGAGGATTCCGCTGAAAATAGTGTCAAAGAA
GAAGAAGATGAAGAAGAAGAAGAAAACGGTGATAATGAAATTAAAGAGGAAGATAACGCA
GATACAAAAATAGAAGTTAAGGATGAAAATGAAGATGATGAAGAAGAAGAAGAATTTAAA
CCTTCGATTAATGGCAATAAAAGAAAGAACGATACACCTGTTGAAAAGGCAGCAGGATTG
TCAAATGCTAAATAAGTGAAAACATCTGGCGGTGATGCAGTTAAGAAACCAGTGTAAAAG
TAACAAGACAGTGATGATGAAGACGATGAAAACAGTGATATTAAATGGAAATATTTAGAG
CATCACGGAGTGCTATTCCCCGATTATTGGTAAAAGCATAATGTAAGACCTAGGTATGAT
GGAAAACCTATTGATTTAAATCTCTTGTAAGAAGAAATGGCTACTTATTGGTCATAAACT
TTAGGAACAGATTGGGAACATAAACCTAAGTACAGAGAGAATTTTTCAAAACAATTCCTC
GATACCTTTGGTAAGGATAAAGGTAAATATGACTTTGATAAGTTCGACTTCACTCCTATA
AAAATACATCTTGAAGAGCAAAAAGAAATCCGTAAAAATCGCTCCAAAGAAGAAAAAAAT
CAAGAAAAGTAGAAAAAAGAAAGGCTTTCTGATTATTATGCTGGCGCAATTCTAGACGGA
TTTAGAGAAAAAGTAGGATAATTCATGATTGAACCTCCAACTCTCTTTAAAGGTAGAGGT
GAACATCCAAAAATGGGTATGATGAAAGGTCGTATTTAACCAGAAGCTGTTGTTATTAAT
ATCTCAAAAGATGCACCTGTCCCAAAATGTTCAGTTCCTGGTCATGGTTGGAGTGAAATA
GTCCACAAACAAGATGTTACTTGGTTAGCAAGCTACAAGGATGATTCTGTAAAGAAGCAA
CATAAATATATCTTCTTATCTGCTGAAAGTAAGCTTAAGGCAGAAAATGATAAAAAGAAA
TACGAAAAAGCAAGACGTCTTAAAAATTTAATTGGATAGATTCGTGAAAATTACGAGAGA
AAATTAAGAAGTAGTGATCCTGTTGATAGATAATTAGGTACTGCTACTTACTTGATTGAT
AAGTTAGCACTCAGAGTTGGTAATGAAAAATCAGAAGAAGAAGCAGATACTGTCGGTTGC
TGCTCTTTGAGAGTTGAGCATATTTAAGTTATAGAAGATACCTAGATTGGATTCGATTTC
TTAGGTAAGGATTCTATGAGATATCAAAATACTGTAAAAGTTACTGAGATTGTTTGGAAA
AATATGTAGTCTTTTATCAAGAATAAAAAACCTGGTGATGATTTATTCGATAGAATTGAT
GCAAGTAGCCTAAATGAATATTTAAAGAGTTAGATGGAAGGTTTGACAGCAAAAGTTTTT
AGAACTTATAATGCTTCTCACACTCTTTAAAAAGAATTAGACAAGGCTGATGAAGAAGGC
CTTGATAAGATGGATTTAAAAGATAAACTTAATTTTTATGATGAAGCTAACAGAAATGTT
GCCATTCTTTGTAACCATCAAAAAACAGTAGGCAAAAACTTTGATGTAATGGTTGGAAAA
ATGGAACAAAGAATTAATGTTTATAAAGATTATGAAAAGGAATTACATACTCATTTAAAC
AAATGCAAAAAGAATGGAGTCAATGCTTATGAAAAAGAAGTTATCTTAGAAGAAAAGGAT
GATGGAAAACATAAAATGTTTGTTAAAAAGTTCCCTGGAACAAAGGAAAAAATTTAAGAA
GCTATTGAAAAAATTAAAAAGAAGATAGACGAAGAATAAAATAAAAAATAATCTAAAGAG
AAGAACAAAGAAATTGCCTTAGGTACTTCTAAAACAAATTACAACGATCCTAGAATATCT
GTTGTTTGGTGTAAAAAGTGGGAAGTTCCTGTAGAAAAAGTTTTCCCTAAAACTCTCATT
GCTAAGTTCGTTTGGGCTATGGATACAGATTTAGAGTGGTCATTCTGA

>TTHERM_01299650(gene)
GTTCTTCAAAAAATTAAAAAATTTATTTAAAAAATAAAAATTATTAATTTTTTTTAAGTA
GAAATTTTTTTCAAATAAATAAATGAATGAATGAATCATGCTAATATTTTTATCAAATTA
ATTTAATATTGAAAATAGACTCTAAATAATAAAATTATATTTTAAATATATAAATGACTT
ATTTACATTTTTCAAAATTATTTTTATATTAGAAGTGTCTCTTTAATGCATGCAAGCAAA
GCTCACATTGCAATAAATCGAACAAACTATTCAATAAATAAATATAATGAGACGTAGAAG
AAATTATTTAATAATAACAATAGCATTATAAATATTTTAATATATTCTTATTTTTTTGTT
TGGGAGTAGCTGCTTTATATATTAGAGGGAAACAAAAAGACTTAGTAAAAAATTAAGAAT
TATTAAAAAAGACTTAGAAAAATTTCTTAAATCGCAACAAAAAAAGACTTAGGAAAAAAA
ACTAAAAATCCCTCACACTTTTAAAGGATAAAAAGATGAGTAGCAAGAAGAACACTAAGA
AAGTCTCTGATAGCGAGGACGATGATTTTGAAGAGGAAGAAGATGAATCAGAAGGTTCAG
GAGAGGAGGATTCCGCTGAAAATAGTGTCAAAGAAGAAGAAGATGAAGAAGAAGAAGAAA
ACGGTGATAATGAAATTAAAGAGGAAGATAACGCAGATACAAAAATAGAAGTTAAGGATG
AAAATGAAGATGATGAAGAAGAAGAAGAATTTAAACCTTCGATTAATGGCAATAAAAGAA
AGAACGATACACCTGTTGAAAAGGCAGCAGGATTGTCAAATGCTAAATAAGTGAAAACAT
CTGGCGGTGATGCAGTTAAGAAACCAGTGTAAAAGTAACAAGACAGTGATGATGAAGACG
ATGAAAACAGTGATATTAAATGGAAATATTTAGAGCATCACGGAGTGCTATTCCCCGATT
ATTGGTAAAAGCATAATGTAAGACCTAGGTATGATGGAAAACCTATTGATTTAAATCTCT
TGTAAGAAGAAATGGCTACTTATTGGTCATAAACTTTAGGAACAGATTGGGAACATAAAC
CTAAGTACAGAGAGAATTTTTCAAAACAATTCCTCGATACCTTTGGTAAGGATAAAGGTA
AATATGACTTTGATAAGTTCGACTTCACTCCTATAAAAATACATCTTGAAGAGCAAAAAG
AAATCCGTAAAAATCGCTCCAAAGAAGAAAAAAATCAAGAAAAGTAGAAAAAAGAAAGGC
TTTCTGATTATTATGCTGGCGCAATTCTAGACGGATTTAGAGAAAAAGTAGGATAATTCA
TGATTGAACCTCCAACTCTCTTTAAAGGTAGAGGTGAACATCCAAAAATGGGTATGATGA
AAGGTCGTATTTAACCAGAAGCTGTTGTTATTAATATCTCAAAAGATGCACCTGTCCCAA
AATGTTCAGTTCCTGGTCATGGTTGGAGTGAAATAGTCCACAAACAAGATGTTACTTGGT
TAGCAAGCTACAAGGATGATTCTGTAAAGAAGCAACATAAATATATCTTCTTATCTGCTG
AAAGTAAGCTTAAGGCAGAAAATGATAAAAAGAAATACGAAAAAGCAAGACGTCTTAAAA
ATTTAATTGGATAGATTCGTGAAAATTACGAGAGAAAATTAAGAAGTAGTGATCCTGTTG
ATAGATAATTAGGTACTGCTACTTACTTGATTGATAAGTTAGCACTCAGAGTTGGTAATG
AAAAATCAGAAGAAGAAGCAGATACTGTCGGTTGCTGCTCTTTGAGAGTTGAGCATATTT
AAGTTATAGAAGATACCTAGATTGGATTCGATTTCTTAGGTAAGGATTCTATGAGATATC
AAAATACTGTAAAAGTTACTGAGATTGTTTGGAAAAATATGTAGTCTTTTATCAAGAATA
AAAAACCTGGTGATGATTTATTCGATAGAATTGATGCAAGTAGCCTAAATGAATATTTAA
AGAGTTAGATGGAAGGTTTGACAGCAAAAGTTTTTAGAACTTATAATGCTTCTCACACTC
TTTAAAAAGAATTAGACAAGGCTGATGAAGAAGGCCTTGATAAGATGGATTTAAAAGATA
AACTTAATTTTTATGATGAAGCTAACAGAAATGTTGCCATTCTTTGTAACCATCAAAAAA
CAGTAGGCAAAAACTTTGATGTAATGGTTGGAAAAATGGAACAAAGAATTAATGTTTATA
AAGATTATGAAAAGGAATTACATACTCATTTAAACAAATGCAAAAAGAATGGAGTCAATG
CTTATGAAAAAGAAGTTATCTTAGAAGAAAAGGATGATGGAAAACATAAAATGTTTGTTA
AAAAGTTCCCTGGAACAAAGGAAAAAATTTAAGAAGCTATTGAAAAAATTAAAAAGAAGA
TAGACGAAGAATAAAATAAAAAATAATCTAAAGAGAAGAACAAAGAAATTGCCTTAGGTA
CTTCTAAAACAAATTACAACGATCCTAGAATATCTGTTGTTTGGTGTAAAAAGTGGGAAG
TTCCTGTAGAAAAAGTTTTCCCTAAAACTCTCATTGCTAAGTTCGTTTGGGCTATGGATA
CAGATTTAGAGTGGTCATTCTGAGATAAAGTAATTTATCATCATTTCTATAAAATATTTA
CATTTCTGGTTAAAATTGTTAAAATAAATAACTAATATAATTATTTATAGAATATTTTCT
GTGTGTTATTCTATTTATGCATTTTTTTATTATATATTCTAAACTAAGAAGAAAAAATTA
GT

>TTHERM_01299650(protein)
MSSKKNTKKVSDSEDDDFEEEEDESEGSGEEDSAENSVKEEEDEEEEENGDNEIKEEDNA
DTKIEVKDENEDDEEEEEFKPSINGNKRKNDTPVEKAAGLSNAKQVKTSGGDAVKKPVQK
QQDSDDEDDENSDIKWKYLEHHGVLFPDYWQKHNVRPRYDGKPIDLNLLQEEMATYWSQT
LGTDWEHKPKYRENFSKQFLDTFGKDKGKYDFDKFDFTPIKIHLEEQKEIRKNRSKEEKN
QEKQKKERLSDYYAGAILDGFREKVGQFMIEPPTLFKGRGEHPKMGMMKGRIQPEAVVIN
ISKDAPVPKCSVPGHGWSEIVHKQDVTWLASYKDDSVKKQHKYIFLSAESKLKAENDKKK
YEKARRLKNLIGQIRENYERKLRSSDPVDRQLGTATYLIDKLALRVGNEKSEEEADTVGC
CSLRVEHIQVIEDTQIGFDFLGKDSMRYQNTVKVTEIVWKNMQSFIKNKKPGDDLFDRID
ASSLNEYLKSQMEGLTAKVFRTYNASHTLQKELDKADEEGLDKMDLKDKLNFYDEANRNV
AILCNHQKTVGKNFDVMVGKMEQRINVYKDYEKELHTHLNKCKKNGVNAYEKEVILEEKD
DGKHKMFVKKFPGTKEKIQEAIEKIKKKIDEEQNKKQSKEKNKEIALGTSKTNYNDPRIS
VVWCKKWEVPVEKVFPKTLIAKFVWAMDTDLEWSF