Identifiers and Description

Gene Model Identifier

TTHERM_01443850

Standard Name

PLK2 (Polo-Like Kinase)

Aliases

PreTt18380 | 392.m00011

Description

PLK2 Serine/Threonine kinase domain protein; Polo-like kinase

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Molecular Function

• ATP binding (IEA) | GO:0005524
• protein kinase activity (IEA) | GO:0004672
• protein serine/threonine kinase activity (IEA) | GO:0004674
• protein tyrosine kinase activity (IEA) | GO:0004713

Biological Process

• cell cycle (IEA) | GO:0007049
• protein phosphorylation (IEA) | GO:0006468

Domains

• ( PF00069 ) Protein kinase domain
• ( PF00659 ) POLO box duplicated region
• ( PF07714 ) Protein tyrosine and serine/threonine kinase

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source	Identifier	Score
Stentor Coeruleus	SteCoe_34553	0
	Description: None
Tetrahymena borealis	EI9_10143.1	9.997093137033517e-262
	Description: protein kinase domain-containing protein (697 aa)
Oxytricha	Contig13304.0.g94	9.997093137033517e-262
	Description: Protein kinase domain
WormBase	WBGene00004043	2.000277046697593e-115
	Description: locus:plk-2 Serine/threonine-protein kinase plk-2 status:Confirmed UniProt:Q9N2L7 protein_id:CCD70415.1
SGD	YMR001C	8.002669202560376e-109
	Description: CDC5 Polo-like kinase with multiple functions in mitosis and cytokinesis through substrate phosphorylation, also functions in adaptation to DNA damage during meiosis; has similarity to Xenopus Plx1 and S. pombe Plo1p; possible Cdc28p substrate
DictyBase	DDB_G0274503	9.996050283847121e-108
	Description: plk on chromosome: 2 position 4379150 to 4382891

General Information

No Data fetched for General Information

Associated Literature

1. Ref:16933976: Eisen JA, Coyne RS, Wu M, Wu D, Thiagarajan M, Wortman JR, Badger JH, Ren Q, Amedeo P, Jones KM, Tallon LJ, Delcher AL, Salzberg SL, Silva JC, Haas BJ, Majoros WH, Farzad M, Carlton JM, Smith RK, Garg J, Pearlman RE, Karrer KM, Sun L, Manning G, Elde NC, Turkewitz AP, Asai DJ, Wilkes DE, Wang Y, Cai H, Collins K, Stewart BA, Lee SR, Wilamowska K, Weinberg Z, Ruzzo WL, Wloga D, Gaertig J, Frankel J, Tsao CC, Gorovsky MA, Keeling PJ, Waller RF, Patron NJ, Cherry JM, Stover NA,

Sequences

>TTHERM_01443850(coding)
ATGTCTTAATAAGCTGCTTAGTAGTAACCCCAGCAAAAATAATCCGAGTAAGGTTAGAAT
AATAACAATGATCAAGGTGTAGCCAACTACCCTACTGAATAAAAGATAATAGAAGAAAAG
ACGGAAAATAAAGTAACAGGTGAAAAGATTATTAAAAAGTATTCTAGAGGAAAGTTATTA
GGTAGTGGAGGTTTTGCAAAATGTTATGAAGTGATTGCTTTAGACACAGATCCGAAGGCA
ATATTTGCTGCCAAGATAATTCCAAAGTCAACTTTAACTAAAAGCAGATAAAGAGTGAAA
TTGATTTCAGAAATTAAAATTCATAAGAGCTTGCATCATAAGAATATTGTTTAGTTTGAG
CATGTTTTTGAGGATCATGATAATGTTTACATTCTTCTTGAATTGTGTCCTTATTAAACT
CTTAATGAGCTAATCAAGCGTAGAAAGCGTATTACAGAATACGAAACATAAATTTACGTA
ATGCAAATAGTGAATGCCCTGAAATATCTCCATTAAAATAAAATTATCCACCGTGATCTT
AAATTGGGCAATCTATTTTTAGGTGACAACATGACACTTAAAATTGGTGATTTTGGTTTA
GCTACTAAAATAGAATATGAAGGAGAGAAAAAGAAAACAGTATGCGGTACTCCTAACTAT
ATAGCACCAGAAATACTTGAAGGAAAAGATGGGCATTCCTATGAAGTTGATATGTGGTCA
TTGGGAGTCATCATTTATACTTTGCTTATTGGAAAGCCTCCATTTGAAACTAAGGACGTC
AGAACTACATATAAAAGAATCAAAATGAACAATTATTGTTTCCCAGAATAGATTTAAATA
TCTGACAATGCTAAGTCTATCATCACTAGCATTTTAAATTTGAATCCTTAAAAACGTCTA
ACATTAGATGAATTATTAGAGCACCCTTTCATGCAAGGAACAGCTTTGAATCCTGAAAAT
TTACCTATTTCTTCTTTAGTGGTGCCATTTTAGAAGCCTAAAAAGGAAGCATTAAAAGAA
AAGAGTAATAACTAAATAGTACAAGATTAAAAGATAGGTTCAGGAAGCTTAGCTTCTACT
TAAAGCTAAATGAATATGGCAGCAACTTAATCTGGGTTATAACTAAACGGAACAAAGGAT
TTAAATGGAAATATGAGGTCTTAAAGCAATAAAAATTTAGGTAGCAACTAAATGGATCAA
GCAAATTTGTTAAAAATGTAGTCTATGCAAACTTTAAAGCACGGATAGTTTAACAGCGAT
TTAAATTCAGAAAATATTTTGGTAAATACTCCTCCAGCTTCAGAAATATGGGTTACTCAA
TGGGTAGATTATTCAAATAAATACGGGTTAGGATATGCACTGAATAATGGAACTATTGGT
GTATTCTTTAATGATTTTACTAAAATTGTAATCGATCCAGAAGGTCAGTATATTGAATAT
TACGAAAAATAGCCTGAAGAGAAATACCAAAAAAGCATAACCTTCACACCTGATAATTAT
CCCTAAGAACTCAAGAAAAAAGTTACCCTTTTAGAGCATTTTAGAAGCTATTTACAAGGC
GATCATGGATCTAACAATTAAAATGCTAATAATAACTACGATGTTAATCCTCCAAGCACA
TTCTTAGATAATTAAACTGGTAAAAAAATGTTGTATTATGTCAAGAAGTGGGTAAAAACA
AAAAATGCTATTTTGTTTCGCTTGCAAAATAAGATTGTACAAGTCAGCTTCTCAGATAAG
ACTGAAATTATTTTAAACAGCATCATGAAAATAGTCACATTTAACAACAAGTAAGGCATT
AGATAAAACTATCCCTTAACTCCTGATCTAAAAATGTACTCACCTGAAATGGAAAAGAGG
TTAAAGTACACGAAGCAAATTCTCACAGATATCCTTAAATAAAGCTAACCTAGTTAAAAC
AATATTAATAACAACCCTTAAAACAACACATAAAGGCAACCAATGCAGCCTTCTTCATTA
TCGAATTAAAATAATTAAAATATAAATACAAATGGTGAATTATTAAACAATTCTTAAAAG
TAAAACTTTGTCCTAAAATGA

>TTHERM_01443850(gene)
ATGTCTTAATAAGCTGCTTAGTAGTAACCCCAGCAAAAATAATCCGAGTAAGGTTAGAAT
AATAACAATGATCAAGGTGTAGCCAACTACCCTACTGAATAAAAGATAATAGAAGAAAAG
ACGGAAAATAAAGTAACAGGTGAAAAGATTATTAAAAAGTATTCTAGAGGAAAGTTATTA
GGTAGTGGAGGTTTTGCAAAATGTTATGAAGTGATTGCTTTAGACACAGATCCGAAGGCA
ATATTTGCTGCCAAGATAATTCCAAAGTCAACTTTAACTAAAAGCAGATAAAGAGTGAAA
TTGATTTCAGAAATTAAAATTCATAAGAGCTTGCATCATAAGAATATTGTTTAGTTTGAG
CATGTTTTTGAGGATCATGATAATGTTTACATTCTTCTTGAATTGTGTCCTTATTAAACT
CTTAATGAGCTAATCAAGCGTAGAAAGCGTATTACAGAATACGAAACATAAATTTACGTA
ATGCAAATAGTGAATGCCCTGAAATATCTCCATTAAAATAAAATTATCCACCGTGATCTT
AAATTGGGCAATCTATTTTTAGGTGACAACATGACACTTAAAATTGGTGATTTTGGTTTA
GCTACTAAAATAGAATATGAAGGAGAGAAAAAGAAAACAGTATGCGGTACTCCTAACTAT
ATAGCACCAGAAATACTTGAAGGAAAAGATGGGCATTCCTATGAAGTTGATATGTGGTCA
TTGGGAGTCATCATTTATACTTTGCTTATTGGAAAGGTAAAAAAACTTTCACAAAATCTA
AATTATTATTTTGAAAGCAGCGATTTCAAAAAATTAATCAATCTCATCTCAAAAAGAAAC
AACTTGAATCAAAAAATTATTATTTTGTTTGAAGGCAATAAAAAATTATTATTTTATTTG
AAAGTAAAAGAAAATTATTATTTTGAAAGCATTAAAAAATTATTTCTTTAATGGTAAATC
AAATACTGAAAGGTCCTTTCAATTTATCATTCTTCTAAAAAATAAAAATATATTTTTGGA
AGAGTAAAATTTTGTTAAAAAATTAAAAATCTATTCCTAAATAAAATGAGTAAATAATTA
AAATTTTAACTAGAACAAAAATAAAAAAGTCAGTGGATTTTTTTTACTAATTGCTAAGAT
TTTGATTTTATAACAATTTAATGAATATTTAGTAACAATTTTTATATAAAAAAGCCTCCA
TTTGAAACTAAGGACGTCAGAACTACATATAAAAGAATCAAAATGAACAATTATTGTTTC
CCAGAATAGATTTAAATATCTGACAATGCTAAGTCTATCATCACTAGCATTTTAAATTTG
AATCCTTAAAAACGTCTAACATTAGATGAATTATTAGAGCACCCTTTCATGCAAGGAACA
GCTTTGAATCCTGAAAATTTACCTATTTCTTCTTTAGTGGTGCCATTTTAGAAGCCTAAA
AAGGAAGCATTAAAAGAAAAGAGTAATAACTAAATAGTACAAGATTAAAAGATAGGTTCA
GGAAGCTTAGCTTCTACTTAAAGCTAAATGAATATGGCAGCAACTTAATCTGGGTTATAA
CTAAACGGAACAAAGGATTTAAATGGAAATATGAGGTCTTAAAGCAATAAAAATTTAGGT
AGCAACTAAATGGATCAAGCAAATTTGTTAAAAATGTAGTCTATGCAAACTTTAAAGCAC
GGATAGTTTAACAGCGATTTAAATTCAGAAAATATTTTGGTAAATACTCCTCCAGCTTCA
GAAATATGGGTTACTCAATGGGTAGATTATTCAAATAAATACGGGTTAGGATATGCACTG
AATAATGGAACTATTGGTGTATTCTTTAATGATTTTACTAAAATTGTAATCGATCCAGAA
GGTCAGTATATTGAATATTACGAAAAATAGCCTGAAGAGAAATACCAAAAAAGCATAACC
TTCACACCTGATAATTATCCCTAAGAACTCAAGAAAAAAGTTACCCTTTTAGAGCATTTT
AGAAGCTATTTACAAGGCGATCATGGATCTAACAATTAAAATGCTAATAATAACTACGAT
GTTAATCCTCCAAGCACATTCTTAGATAATTAAACTGGTAAAAAAATGTTGTATTATGTC
AAGAAGTGGGTAAAAACAAAAAATGCTATTTTGTTTCGCTTGCAAAATAAGATTGTACAA
GTCAGCTTCTCAGATAAGACTGAAATTATTTTAAACAGCATCATGAAAATAGTCACATTT
AACAACAAGTAAGGCATTAGATAAAACTATCCCTTAACTCCTGATCTAAAAATGTACTCA
CCTGAAATGGAAAAGAGGTTAAAGTACACGAAGCAAATTCTCACAGATATCCTTAAATAA
AGCTAACCTAGTTAAAACAATATTAATAACAACCCTTAAAACAACACATAAAGGCAACCA
ATGCAGCCTTCTTCATTATCGAATTAAAATAATTAAAATATAAATACAAATGGTGAATTA
TTAAACAATTCTTAAAAGTAAAACTTTGTCCTAAAATGA

>TTHERM_01443850(protein)
MSQQAAQQQPQQKQSEQGQNNNNDQGVANYPTEQKIIEEKTENKVTGEKIIKKYSRGKLL
GSGGFAKCYEVIALDTDPKAIFAAKIIPKSTLTKSRQRVKLISEIKIHKSLHHKNIVQFE
HVFEDHDNVYILLELCPYQTLNELIKRRKRITEYETQIYVMQIVNALKYLHQNKIIHRDL
KLGNLFLGDNMTLKIGDFGLATKIEYEGEKKKTVCGTPNYIAPEILEGKDGHSYEVDMWS
LGVIIYTLLIGKPPFETKDVRTTYKRIKMNNYCFPEQIQISDNAKSIITSILNLNPQKRL
TLDELLEHPFMQGTALNPENLPISSLVVPFQKPKKEALKEKSNNQIVQDQKIGSGSLAST
QSQMNMAATQSGLQLNGTKDLNGNMRSQSNKNLGSNQMDQANLLKMQSMQTLKHGQFNSD
LNSENILVNTPPASEIWVTQWVDYSNKYGLGYALNNGTIGVFFNDFTKIVIDPEGQYIEY
YEKQPEEKYQKSITFTPDNYPQELKKKVTLLEHFRSYLQGDHGSNNQNANNNYDVNPPST
FLDNQTGKKMLYYVKKWVKTKNAILFRLQNKIVQVSFSDKTEIILNSIMKIVTFNNKQGI
RQNYPLTPDLKMYSPEMEKRLKYTKQILTDILKQSQPSQNNINNNPQNNTQRQPMQPSSL
SNQNNQNINTNGELLNNSQKQNFVLK