Identifiers and Description

Gene Model Identifier

TTHERM_00348580

Standard Name

COI7 (COnjugation-Induced 7)

Aliases

PreTt05270 | 36.m00234 | 3703.m00096

Description

COI7 Specifically expressed during conjugation; hypothetical protein

Genome Browser (Macronucleus)

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Genome Browser (Micronucleus)

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External Links

Gene Ontology Annotations

No Data fetched for Gene Ontology Annotations

Domains

No Data fetched for Domains

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

No Data fetched for Homologs

General Information

No. Gene Name(s) Paragraph Text
2321 COI7, COI6, JMJ1, LIA5 Coi6p, its interaction partners Coi7p and Lia5p, and the histone demethylase Jmj1p are crucial for confining the production of small RNAs and the formation of heterochromatin to the eliminated sequences. The loss of Coi6p, Coi7p or Jmj1p causes ectopic DNA elimination.
2320 COI7, COI6 Coi7p directly interacts with Coi6p and is required for the stable accumulation of Coi6p.

Associated Literature

  1. Ref:29021213: Noto T, Mochizuki K (2017) Whats, hows and whys of programmed DNA elimination in Tetrahymena. Open biology 7(10):
  2. Ref:28273462: Suhren JH, Noto T, Kataoka K, Gao S, Liu Y, Mochizuki K (2017) Negative Regulators of an RNAi-Heterochromatin Positive Feedback Loop Safeguard Somatic Genome Integrity in Tetrahymena. Cell reports 18(10):2494-2507
  3. Ref:25588944: Woehrer SL, Aronica L, Suhren JH, Busch CJ, Noto T, Mochizuki K (2015) A Tetrahymena Hsp90 co-chaperone promotes siRNA loading by ATP-dependent and ATP-independent mechanisms. The EMBO journal 34(4):559-77

Sequences 

>TTHERM_00348580(coding)
ATGGAATTACTAGATTCAGATATAGGCTCTCAAATAAATTAGTAGGTTGAAGGAAAAAAT
TTTAAAGAAGTGGAGGATATCTATTTACAAAATATACAATCTGCTAAATTCACCTCGGAA
TACAGAGAAAAAATTTAATCTTTCCCAAATTTAATATGCTTTAGCCTCACTAACATGAAT
TTCAGCAAAATATAAGATCTTCCTATTTTAAAGAGACTGCTAAGATTAGAGATATGTTAT
TGCACCTTCGATATCAGTAGTCTCAATTAAATTTACATTTAATTTCCAAGGCTTGTGAGT
TTAAGGCTAGTTGGATGTAATATTAGCTCATATTCATAAATTGAATGTTTAACAAGCTTG
CCAGACTTGGCCTAATTAGATCTATTTAATAATCCTATTTACAAATTTAATTACGAATAT
CAGAGCTTTCATTAAAAAATGTTCGAATTATTTCCTAAATTGATGTATTTGGACAATCTT
AAAAAAGATTTCTCAAGAGCTTGTACCATTCCTATAAATTAGATTGATCCAAAATAACTT
ATTCAAGAAGTTGAAATCCCTAAATTTGTAGATAAACTCAACAGATCAAACATAAACTCT
TAGAATAATAGTTTTAATTCTAATAAATTGACACGTAAAAATAATATTAACAATCCAAAC
AAAAGAAGGGCTGACAATTCAGACGAAGAGGATGATGACCTTGATGAAGATTACCAAGAA
GATAGTGATGAACCATCAAATCAAAGACATGGCTATCAAACTAGAAAATAATAGAAATTA
GCTGCATACAAATGA



>TTHERM_00348580(gene)
AAATTAAAAAATAAAAAATAAAATAGAATAAATAAATGGAATTACTAGATTCAGATATAG
GCTCTCAAATAAATTAGTAGGTTGAAGGAAAAAATTTTAAAGAAGTGGAGGATATCTATT
TACAAAATATACAATCTGCTAAATTCACCTCGGAATACAGAGAAAAAATTTAATCTTTCC
CAAATTTAATATGCTTTAGCCTCACTAACATGAATTTCAGCAAAATATAAGATCTTCCTA
TTTTAAAGAGACTGCTAAGATTAGAGATATGTTATTGCACCTTCGATATCAGTAGTCTCA
ATTAAATTTACATTTAATTTCCAAGGCTTGTGAGTTTAAGGCTAGTTGGATGTAATATTA
GCTCATATTCATAAATTGAATGTTTAACAAGCTTGCCAGACTTGGCCTAATTAGATCTAT
TTAATAATCCTATTTACAAATTTAATTACGAATATCAGAGCTTTCATTAAAAAATGTTCG
AATTATTTCCTAAATTGATGTATTTGGACAATCTTAAAAAAGATTTCTCAAGAGCTTGTA
CCATTCCTATAAATTAGATTGATCCAAAATAACTTATTCAAGAAGTTGAAATCCCTAAAT
TTGTAGATAAACTCAACAGATCAAACATAAACTCTTAGAATAATAGTTTTAATTCTAATA
AATTGACACGTAAAAATAATATTAACAATCCAAACAAAAGAAGGGCTGACAATTCAGACG
AAGAGGATGATGACCTTGATGAAGATTACCAAGAAGATAGTGATGAACCATCAAATCAAA
GACATGGCTATCAAACTAGAAAATAATAGAAATTAGCTGCATACAAATGACTGAATAAAA
TATAGTTGTTAAAGTTTCAGCAAATTATAATAAAACATATTTATCATTCATTAAAAATGT
TCTCAAAAATTAAACAGCATATAAAATCCATGTTTTATTTC



>TTHERM_00348580(protein)
MELLDSDIGSQINQQVEGKNFKEVEDIYLQNIQSAKFTSEYREKIQSFPNLICFSLTNMN
FSKIQDLPILKRLLRLEICYCTFDISSLNQIYIQFPRLVSLRLVGCNISSYSQIECLTSL
PDLAQLDLFNNPIYKFNYEYQSFHQKMFELFPKLMYLDNLKKDFSRACTIPINQIDPKQL
IQEVEIPKFVDKLNRSNINSQNNSFNSNKLTRKNNINNPNKRRADNSDEEDDDLDEDYQE
DSDEPSNQRHGYQTRKQQKLAAYK