Identifiers and Description

Gene Model Identifier

TTHERM_00497900

Standard Name

FLP1 (FLiPpase)

Aliases

PreTt06955 | 62.m00239 | 3715.m00100

Description

FLP1 phospholipid-translocating P-type ATPase flippase family protein

Genome Browser (Macronucleus)

Full Screen View


Genome Browser (Micronucleus)

Full Screen View

External Links

Gene Ontology Annotations

Molecular Function

Biological Process

Domains

  • ( PF00122 ) E1-E2 ATPase
  • ( PF00702 ) haloacid dehalogenase-like hydrolase
  • ( PF06637 ) PV-1 protein (PLVAP)
  • ( PF06686 ) Stage III sporulation protein AC/AD protein family
  • ( PF08282 ) haloacid dehalogenase-like hydrolase
  • ( TIGR00099 ) Cof-like hydrolase
  • ( TIGR00338 ) phosphoserine phosphatase SerB
  • ( TIGR01116 ) calcium-translocating P-type ATPase, SERCA-type
  • ( TIGR01482 ) Sucrose-phosphate phosphatase subfamily
  • ( TIGR01484 ) HAD-superfamily hydrolase, subfamily IIB
  • ( TIGR01488 ) HAD-superfamily hydrolase, subfamily IB (PSPase-like)
  • ( TIGR01494 ) ATPase, P-type (transporting), HAD superfamily,
  • ( TIGR01517 ) calcium-translocating P-type ATPase, PMCA-type
  • ( TIGR01522 ) calcium-transporting P-type ATPase, PMR1-type
  • ( TIGR01524 ) magnesium-translocating P-type ATPase
  • ( TIGR01525 ) heavy metal translocating P-type ATPase
  • ( TIGR01647 ) plasma-membrane proton-efflux P-type ATPase
  • ( TIGR01652 ) phospholipid-translocating P-type ATPase, flippase
  • ( TIGR02886 ) anti-sigma F factor antagonist

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

Source Identifier Score
Stentor Coeruleus SteCoe_29926 0
Description: None
WormBase WBGene00009498 9.997093137033517e-262
Description: locus:tat-5 status:Confirmed UniProt:G5EGE0 protein_id:CAD92377.1
Tetrahymena borealis EI9_12681.1 9.997093137033517e-262
Description: phospholipid-translocating P-type ATPase, flippase (1090 aa)
Oxytricha Contig899.1.g81 9.997093137033517e-262
Description: E1-E2 ATPase
SGD YIL048W 9.997093137033517e-262
Description: NEO1 Putative aminophospholipid translocase (flippase) involved in endocytosis and vacuolar biogenesis; localizes to endosomes and the Golgi aparatus
DictyBase DDB_G0270870 6.998081184481452e-172
Description: atp9b on chromosome: 1 position 2777615 to 2781943

General Information

No. Gene Name(s) Paragraph Text
19 FLP10, FLP19, FLP18, FLP17, FLP8, FLP16, FLP15, FLP14, FLP6, FLP13, FLP11, FLP2, FLP1, DNF1 , FLP9, FLP12, FLP4, FLP7, FLP5 The phospholipid flippase family of genes in Tetrahymena contains 20 members, FLP1-FLP20. Preliminary studies show that many of these genes are differentially regulated in response to temperature and/or the presence of a polycyclic aromatic hydrocarbon (pyrene).

Associated Literature

No Data fetched for Associated Literature

Sequences 

>TTHERM_00497900(coding)
ATGGCTGAGGACTCAGGTGATGAGATAGAACTTTAAATGAAGGATTAGAATGATGTTAGT
GATGGGAAAAATTATTTAGAGCCTAATGGGCAAGAAGAGGATCTTTTGTTTAAAAAGAAT
AAAAATAAAAAGAAATCAGTTAGTTTTTTTTCCAAGCTGTACAATTGCTTGAGTGGTAAT
TCTTAGCATGAAGGAGATAGAAAAATTTACTTAGATGGGCATTCAGTGCCTAAAATAAAT
GTGCAAAATGTTGTGAGAAATCAAAAATATAACATTTTTACTTTTATTCCTTGTGTGCTT
TACAATCAATTCAAGTTTTTCTTCAACTTTTTTTATTTATTAATATGCATTTCTCAGTTT
ATTCCAGCCTTAACTGTAGGGTTTCTCTTCACTTACATAGCTCCTTTAGCTTTTGTGCTA
ATTTTAACTATGATTAAAGATGCATACGACGATTACAAAAGATATAAAAGAGACAAAGAA
GCAAATAGTTCACTTTATGAAGTTATTGTCAACGGACAAATAAAATTAATTCCTAGTATG
AACTTAAAAGTAGGATAAATCGTAAAAGTAAATTTAAAATAAAGAATTCCTGCTGATTTA
ATTATACTCACTGCTTCTGAGCCAAATGGTACTGTTTTTATCCGTACAGACTAGCTTGAT
GGTGAAACAGACTGGAAAATTAGAAAATGTATCAGACATACACAAAACGAAGTCGACTTT
TAAAATGCTGTAAGTCTTTAAAAGCTGGGAGGTCACGTTGTCATTAACTAGCCTTAAGAA
AATATCTATGAGTTTTCAGGTTTATATAAATTTAATGATCACTAAGAACCACTTAATTTA
GAAAACACTCTCTGGTGCAACACAATTTTAGCATCTGGACATATATGGGGTTTGGTCATA
CACACAGGAAAGGAAACAAGAATGGCTATGAATTCAAGGCATCCTAGAAGCAAATTTGGG
CTCTTTGATGAAGAAGTCAACTAGCTATCAAAAATATTATTTTACTTTATGATTATCCTT
TCATTTGTAATGATACTTTTCCATGGATTCACATCTCTATGGGTAATTTAGTATTTCCGT
TACCTACTTTTGCTAAGTAGCATCATACCCATTTCCTTAAGAGTTAACAATGACTTTGCA
AAAGCAGTATTCTCCTATTAAATTCAAAACGATAAGTCTATTGAAGGTACAGTCGCAAGA
AACTCTAATATACCAGAAGAATTAGGAAGAATATAATACGTTTTGGCAGATAAAACAGGA
ACTCTCACACAAAACGATATGATATTTAAAAAGATTATTATCAGTGAGAAATAATATACA
GAAGAAGACTTCAATGAAATTAGATCCATTCTTTCCAAACATTGCCAAAAACACAAAGGT
CCACTTTCTGATGTAGAAGGTGATACAATTGCAGAAAATAAAAGGCATTTGCGCAGAAAA
AATGATTATTTACTTAGAGATGCAATCACAGCACTAGCAGTCTGCCACAACGTTACTCCA
GTTATTGAAGACGGAGAAACCGTTCTTTAAGCATCAAGTCCTGATGAGCATGCACTTGTG
AAATTCGCACAAAGCTTAAATATAACTCTGCTTTCAAGAGATGAGCAAAAAGTAGTTGTA
AGAAATGCTGCTAAAGAAGAAGAGCACTTTGAAATTCTTGCTTGCTTTCCCTTCAGCTCC
GAAACCAAAAGAATGGGTATACTTGTTAGACACTAAAAGACCAATAAAATTATATACTAC
TTGAAAGGTGCTGATGCTATCATGGTAACGAGAGTAAGAAAAGTTTACCATCCACTTATC
AATGATGACTGTGACAATCTAGCTAGAGAAGGTCTTCGTACTCTTGTTGTTGCACAAAAG
CTGATTTCAGAAGAGTTTTACAAGGATTGGAGAGCCAAGTACAATAAAGCATAAGAACAC
ATGCAAAATAGAAATGCAAAAATTAGAGAAGTTGCTGAGTTATTAGAAGTAGATATGGAG
CTTTTAGCTGTTACAGGTGTAGAAGATAAACTTCAAGATGAAGTCTGCTCTACAATTGAA
AGTATGAGGTAAGGTGGGATAAAAGTGTGGATGCTTACAGGAGATAAAGTAGAAACAGCT
AAATGTATAGCAATCAGTGCAGGTTTGTAATCAAGAAATTAAGAAATATTTGAAATCAAA
GATGAAACAGATGAAATGGCTATAAGAGAACTGATTAATAAATTTTCTCATAAATCTGAT
TGTGTTTTACTAATTGATGGTGTATCACTGACTAGAGTAATATAATCTTGCTCAAAAATT
TTCTTTGAAACTGCTTGCCAAGCTCCAGCTGTAATTTGTTGTAGATGTGCACCCAAATAA
AAGGCTGAAGTTACAGAGATGCTTAAAAAATACTCCAAAAAAAGAGTACTTTGTATTGGT
GATGGTGGTAATGATGTCGGTATGATATAATGTGCTCATGTAGGAGTAGGTATTGTAGGA
AAAGAAGGAAAACAAGCTGCTTTAGCCTCTGATTTTTCAATTTTAGAATTCAAACACATC
AAGTAGTTATTATTTTGGCATGGTAGAAACTCATATAAAAAAGCAACCACATTAAGTTTG
TTTGTCATCCATAGAGGTTTAATTATAAGTATTATCTAATTTGTTTTCAGTAGTGTCTTC
TATTTTGTAGCCATTCCTATTTACAATGGTATGCTGATGCTTGGTTATTCAACTTTTTAT
ACATCTTTACCTGTCTTCTGTTTGATTTTTGACTAAGATATTTCTTAAAAAATGGTTCAA
CAGTACCCTTAATTATATAAAACTCTATAAAGAAACAAAAGAATGAGCACAAAATCAATA
TTAGTATGGATCTGGATTAGCATTTACTAAGGAGCTTTAATCATGCTTATGACTTTAACT
ATGTTTAAAGAAGCCTTTTTAAATATTGTGACCATTACATTTACGTCATTAATTTTTATT
GAGCTTTTGAATGTATACTCATAGATTCATACATTCCATTTTGCAATGGTAGTAAGTCAG
GTATTCACGTTCCTTTTATATGTTCTAAGTATCATATTCTTAAATAATTATATTGATACT
GCTTAAATAAATATTCACTTCTTTGTTAAAGTTTCTTTGATTTGCTTATGCACATGGCTA
CCTGTTCATACATTTAAGATAATTTAATAAGCTTGTTATCCTAGTGAAGAAAAAAAAATA
ATGCGTCAAGTATTTACCTTAAAAGATTTCTTAGGAGTTTTAATAGGATTTGCTAGCTTA
TTGATATTTGTATTTTTATATGCAAATTGA


>TTHERM_00497900(gene)
ATGGCTGAGGACTCAGGTGATGAGATAGAACTTTAAATGAAGGATTAGAATGATGTTAGT
GATGGGAAAAATTATTTAGAGCCTAATGGGCAAGAAGAGGATCTTTTGTTTAAAAAGAAT
AAAAATGTAGAAATTAAATTCTTATATTTTAAAAGCGAATCCAATAGAATGAAAGTGATT
AAAGCATTTAAATTTAACAGTTTTTCTAAGTAGAAAAGCAAAAATAAAACATTTTTTTAT
TTGAAATTTGGAAACAAAGCCATATTTATTTATTTAGAACTAAAATATATTTGTAATATT
AGATTTATGAAAATATTTATCATTAATTTTAATAGAAAAAGAAATCAGTTAGTTTTTTTT
CCAAGCTGTACAATTGCTTGAGTGGTAATTCTTAGCATGAAGGAGATAGAAAAATTTACT
TAGATGGGCATTCAGTGCCTAAAATAAATGTGCAAAATGTTGTGAGAAATCAAAAATATA
ACATTTTTACTTTTATTCCTTGTGTGCTTTACAATCAATTCAAGTTTTTCTTCAACTTTT
TTTATTTATTAATATGCATTTCTCAGTTTATTCCAGCCTTAACTGTAGGTAAATAGAGTT
CATTTAATTATTTGAAATGTCTTTTGAGAAATAAATATTAGCCCTAATTGTATTTTGAGA
ATATAGATGGTAAAAACTATTTTTTTTAATTTATAGGGTTTCTCTTCACTTACATAGCTC
CTTTAGCTTTTGTGCTAATTTTAACTATGATTAAAGATGCATACGACGATTACAAAAGAT
ATAAAAGAGACAAAGAAGCAAATAGTTCACTTTATGAAGTTATTGTCAACGGACAAATAA
AATTAATTCCTAGTATGAACTTAAAAGTAGGATAAATCGTAAAAGTAAATTTAAAATAAA
GAATTCCTGCTGATTTAATTATACTCACTGCTTCTGAGCCAAATGGTACTGTTTTTATCC
GTACAGACTAGCTTGATGGTGAAACAGACTGGAAAATTAGAAAATGTATCAGACATACAC
AAAGTAAAAATAGTTTAAAATAAACTATTACGTTTATTATTACAATTTTTTGTTACTTTG
AATATTTTTGTGATTTACGAGAAATAAATAAATAAAAAAATAAATAGACTGGTTTCGTAA
TTTACTGATAAATTAAGGTTGTGTTGTAATTCAAAAATTTTAATGTTATTGAGTAACTAA
ATTTTCATAAATAATTTGTCTATTAGATATGCTTTTTATTTAAATTTAACAAGAACCAGC
TTTTATCAATAATTTTACTTTTTTATTCTTACTATAACTATTTTAAATTAATAGACGAAG
TCGACTTTTAAAATGCTGTAAGTCTTTAAAAGCTGGGAGGTCACGTTGTCATTAACTAGC
CTTAAGAAAATATCTATGAGTTTTCAGGTTTATATAAATTTAATGATCACTAAGAACCAC
TTAATTTAGAAAACACTCTCTGGTGCAACACAATTTTAGCATCTGGACATATATGGGGTT
TGGTCATACACACAGGAAAGGAAACAAGAATGGCTATGAATTCAAGGCATCCTAGAAGCA
AATTTGGGCTCTTTGATGAAGAAGTCAACTAGCTATCAAAAATATTATTTTACTTTATGA
TTATCCTTTCATTTGTAATGATACTTTTCCATGGATTCACATCTCTATGGGTAATTTAGT
ATTTCCGTTACCTACTTTTGCTAAGTAGCATCATACCCATTTCCTTAAGAGTTAACAATG
ACTTTGCAAAAGCAGTATTCTCCTATTAAATTCAAAACGATAAGTCTATTGAAGGTACAG
TCGCAAGAAACTCTAATATACCAGAAGAATTAGGAAGAATATAATACGTTTTGGCAGATA
AAACAGGAACTCTCACACAAAACGATATGATATTTAAAAAGATTATTATCAGTGAGAAAT
AATATACAGAAGAAGACTTCAATGAAATTAGATCCATTCTTTCCAAACATTGCCAAAAAC
ACAAAGGTCCACTTTCTGATGTAGAAGGTGATACAATTGCAGAAAATAAAAGGCATTTGC
GCAGAAAAAATGATTATTTACTTAGAGATGCAATCACAGCACTAGCAGTCTGCCACAACG
TTACTCCAGTTATTGAAGACGGAGAAACCGTTCTTTAAGTAAACATACTTTTTTTCTCAA
ATTTAATTATTTAGCAAATAATAAATAATAAAGGCATCAAGTCCTGATGAGCATGCACTT
GTGAAATTCGCACAAAGCTTAAATATAACTCTGCTTTCAAGAGATGAGCAAAAAGTAGTT
GTAAGAAATGCTGCTAAAGAAGAAGAGCACTTTGAAATTCTTGCTTGCTTTCCCTTCAGC
TCCGAAACCAAAAGAATGGGTATACTTGTTAGACACTAAAAGACCAATAAAATTATATAC
TACTTGAAAGGTGCTGATGCTATCATGGTAACGAGAGTAAGAAAAGTTTACCATCCACTT
ATCAATGATGACTGTGACAATCTAGCTAGAGAAGGTCTTCGTACTCTTGTTGTTGCACAA
AAGCTGATTTCAGAAGAGTTTTACAAGGATTGGAGAGCCAAGTACAATAAAGCATAAGAA
CACATGCAAAATAGAAATGCAAAAATTAGAGAAGTTGCTGAGTTATTAGAAGTAGATATG
GAGCTTTTAGGTAATTATTAATATCTATTTGTATATTAAGTAAATTAAAATAAATTAATA
ATTTTAATAGCTGTTACAGGTGTAGAAGATAAACTTCAAGATGAAGTCTGCTCTACAATT
GAAAGTATGAGGTAAGGTGGGATAAAAGTGTGGATGCTTACAGGAGATAAAGTAGAAACA
GCTAAATGTATAGCAATCAGTGCAGGTTTGTAATCAAGAAATTAAGAAATATTTGAAATC
AAAGATGAAACAGATGAAATGGCTATAAGAGAACTGATTAATAAATTTTCTCATAAATCT
GATTGTGTTTTACTAATTGATGGTGTATCACTGACTAGAGTAATATAATCTTGCTCAAAA
ATTTTCTTTGAAACTGCTTGCCAAGCTCCAGCTGTAATTTGTTGTAGATGTGCACCCAAA
TAAAAGGCTGAAGTTACAGAGATGCTTAAAAAATACTCCAAAAAAAGAGTACTTTGTATT
GGTGATGGTGGTAATGATGTCGGTATGATATAATGTGCTCATGTAGGAGTAGGTATTGTA
GGAAAAGAAGGAAAACAAGCTGCTTTAGCCTCTGATTTTTCAATTTTAGAATTCAAACAC
ATCAAGTAGTTATTATTTTGGCATGGTAGAAACTCATATAAAAAAGGTAAATAAACATTT
TTTTAATTACTATGATTTAAATCTACCTAAAAAATAATTAAGATAAATATTGATTCTAAA
AGAAAATTTAAATGTTAAATTTTAAAGAATAAAATTTTATTTCAGCATTTTAAGTTTGCT
GTTCAGCATCTTAAAATTTATTAATGATTTTGAAAAAAAATCTATTTATAAAATTACATT
TTTATAAGACAATTAACAAATTATTGAAATTAAGAATTAATTTTGAACAAAAATATAACA
AAGATTTTAAATTTAATTTTCTAAATTCTAAAATTTAAATAAATTTAATATTTTACTATA
AAGCAACCACATTAAGTTTGTTTGTCATCCATAGAGGTTTAATTATAAGTATTATCTAAT
TTGTTTTCAGTAGTGTCTTCTATTTTGTAGCCATTCCTATTTACAATGGTATGCTGATGC
TTGGTTATTCAACTTTTTATACATCTTTACCTGTCTTCTGTTTGATTTTTGACTAAGATA
TTTCTTAAAAAATGGTTCAACAGTACCCTTAATTATATAAAACTCTATAAAGAAACAAAA
GAATGAGCACAAAATCAATATTAGTATGGATCTGGATTAGCATTTACTAAGTAATTAAGT
TAATCAAATTATATTTATCTAATAATTTTTACTACTAACAGGGAGCTTTAATCATGCTTA
TGACTTTAACTATGTTTAAAGAAGCCTTTTTAAATATTGTGACCATTACATTTACGTCAT
TAATTTTTATTGAGCTTTTGAATGTATACTCATAGGTAAATTAACACTTTTAAAAATATT
CTATAATAAATACAAATTTTAATGTTAACAAACCAAAGTTTATTAGCTTTGAGATATAAT
ATAACAAAGAATTTAGAAATTATTTACTAAACTAAAATTGAAAAAAATTATTATTAAAAT
AGATTCATACATTCCATTTTGCAATGGTAGTAAGTCAGGTATTCACGTTCCTTTTATATG
TTCTAAGTATCATATTCTTAAATAATTATATTGATACTGCTTAAATAAATATTCACTTCT
TTGTTAAAGTTTCTTTGATTTGCTTATGCACATGGCTACCTGTTCATACATTTAAGATAA
TTTAATAAGCTTGTTATCCTAGTGAAGAAAAAAAAATAATGCGTCAAGTATTTACCTTAA
AAGATTTCTTAGGAGTTTTAATAGGATTTGCTAGCTTATTGATATTTGTATTTTTATATG
CAAATTGA


>TTHERM_00497900(protein)
MAEDSGDEIELQMKDQNDVSDGKNYLEPNGQEEDLLFKKNKNKKKSVSFFSKLYNCLSGN
SQHEGDRKIYLDGHSVPKINVQNVVRNQKYNIFTFIPCVLYNQFKFFFNFFYLLICISQF
IPALTVGFLFTYIAPLAFVLILTMIKDAYDDYKRYKRDKEANSSLYEVIVNGQIKLIPSM
NLKVGQIVKVNLKQRIPADLIILTASEPNGTVFIRTDQLDGETDWKIRKCIRHTQNEVDF
QNAVSLQKLGGHVVINQPQENIYEFSGLYKFNDHQEPLNLENTLWCNTILASGHIWGLVI
HTGKETRMAMNSRHPRSKFGLFDEEVNQLSKILFYFMIILSFVMILFHGFTSLWVIQYFR
YLLLLSSIIPISLRVNNDFAKAVFSYQIQNDKSIEGTVARNSNIPEELGRIQYVLADKTG
TLTQNDMIFKKIIISEKQYTEEDFNEIRSILSKHCQKHKGPLSDVEGDTIAENKRHLRRK
NDYLLRDAITALAVCHNVTPVIEDGETVLQASSPDEHALVKFAQSLNITLLSRDEQKVVV
RNAAKEEEHFEILACFPFSSETKRMGILVRHQKTNKIIYYLKGADAIMVTRVRKVYHPLI
NDDCDNLAREGLRTLVVAQKLISEEFYKDWRAKYNKAQEHMQNRNAKIREVAELLEVDME
LLAVTGVEDKLQDEVCSTIESMRQGGIKVWMLTGDKVETAKCIAISAGLQSRNQEIFEIK
DETDEMAIRELINKFSHKSDCVLLIDGVSLTRVIQSCSKIFFETACQAPAVICCRCAPKQ
KAEVTEMLKKYSKKRVLCIGDGGNDVGMIQCAHVGVGIVGKEGKQAALASDFSILEFKHI
KQLLFWHGRNSYKKATTLSLFVIHRGLIISIIQFVFSSVFYFVAIPIYNGMLMLGYSTFY
TSLPVFCLIFDQDISQKMVQQYPQLYKTLQRNKRMSTKSILVWIWISIYQGALIMLMTLT
MFKEAFLNIVTITFTSLIFIELLNVYSQIHTFHFAMVVSQVFTFLLYVLSIIFLNNYIDT
AQINIHFFVKVSLICLCTWLPVHTFKIIQQACYPSEEKKIMRQVFTLKDFLGVLIGFASL
LIFVFLYAN