Identifiers and Description

Gene Model Identifier

TTHERM_01359440

Standard Name

FLP16 (FLiPpase)

Aliases

PreTt21697 | 346.m00012

Description

FLP16 phospholipid-translocating P-type ATPase flippase family protein; P-type ATPase, C-terminal

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Cellular Component

• plastid large ribosomal subunit (IEA) | GO:0000311

Molecular Function

• C5L2 anaphylatoxin chemotactic receptor binding (IEA) | GO:0031715
• G protein-coupled serotonin receptor binding (IEA) | GO:0031821

Biological Process

• loss of chromatin silencing (IEA) | GO:0006345
• mannosyl-inositol phosphorylceramide metabolic process (IEA) | GO:0006675
• mitotic nuclear division (IEA) | GO:0007067
• negative regulation of interleukin-1 production (IEA) | GO:0032692
• obsolete activation of MAPK activity (IEA) | GO:0000187
• obsolete cellular response to tetrachloromethane (IEA) | GO:1904773

Domains

• ( PF13246 ) Cation transport ATPase (P-type)
• ( PF16209 ) Phospholipid-translocating ATPase N-terminal
• ( PF16212 ) Phospholipid-translocating P-type ATPase C-terminal

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

No Data fetched for Homologs

General Information

No.	Gene Name(s)	Paragraph Text
2226	FLP6, FLP16, FLP19, FLP2, FLP8, FLP15, FLP4, FLP9, FLP12, FLP11, FLP13, FLP5, FLP14, FLP1, FLP18, FLP10, FLP17, FLP7, DNF1	The phospholipid flippase family of genes in Tetrahymena contains 20 members, FLP1-FLP20. Preliminary studies show that many of these genes are differentially regulated in response to temperature and/or the presence of a polycyclic aromatic hydrocarbon (pyrene).

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_01359440(coding)
ATGTAGATTTATTAAGTCGATAAGGTAAATAAGATCCAAAATTCTTATGAGAATGCAATA
GAAAAGCCATATCTATACTGCTTTAAAAAGAAAGTAGCAAGAAAGTAGGAACTTAGGTCA
GTTTACGCAGGAATACCTGATAATTAGGTTTGCAATAATAGGATTTAGACATCAAAATAC
AATTATTTAACCTTCATTCCTAAGAATTTACTAGTTTAGTTTAGCAAACTCGCAAATATA
TACTTTATTATTATTGGTATTTGTCAAATCATACCTTAAATTACTACTACTGATGGAAAG
CCTCTCGTTTATACTCCTTTAGGCATAATTATTTTTATAAGTATGGTAAAGGATTTTATC
GAAGATAGAAAAAGGAGAAAACAAGATGAATATGAAAATAAATCTTTAACAAACAGGTTT
AATGCTTCGTCCGGGGAATTTGAAAAAGTAGCATGGGAAGAACTTACAATTGGCGATATT
ATTAAAGTTGACTTAAATGAGCGATTTCCTGCTGACATTTTGATTCTTTCTACTACTAAT
CAATATGGAAATTGTTATGTTGAGACCAAAAATTTAGATGGAGAAACAAATTTAAAGCTG
AGACAGAGTTGTGCATCTCTCATTTTTACTGATGAAAATGCTGTTAAGAATGTAAACAAT
ATTGGGAGATTTTAATTTTAATATGAAGACCCAAATTATCGCATACACAGTTTCAATGGA
ATAATGATGGATGAACAAGAGAAAGATCCTTCAAAAAGCAAATATCCTCTTTCTTTGTAA
AATATATGCTTGAGAGGATGCACTCTTAAACGTACTCACTCGATTACAGCTGTTGTTATA
TATTCTGGACACGATTGCAAGTCTTTGAAATATGCCTAAAGAGGACACTATAAATTTGGC
ACAGTTGAAAAGATGATGAACAAAATGGTTTTTTATATTTTCTTGATCCTTATATTAATA
AGCATATTCTGTGCTGCTTATTATGTGATTTGGTATAGCTACAAAAAAGACGAACTTACT
TACCTTCATATAGGAGAACATGACATTGAGTCTTACCCTGCAGGAGATTTCTTTCTCAGA
ATTCCAATGTGGGTTTTACTCCTAAGTAACTTTGTTCCCATATCGCTTCTAGTAACTCTT
GAAATTGTGAAGTATCTCCAAGGATAGCTGTTAACAAGAGACAAAAATTTTGTAAATAAA
TTAAGTGACGAACTAGTAGAAGTAAATAGTAGTAATTTGATAGATTAGCTTGGACAAGTC
AGGTACATCCTCACTGATAAAACAGGTACGTTGACTGGAAATGTTATGAAATTCAAAGCA
TTATCTGTCAATAGCAACTCTTACGAGCATACTGCATATGACGATAATGGAATTCTTAAT
AGTACAAAGTTGCTTGAGTAATTAAAGGATTCATCAGAAAATCAACTTGAATATGAAGCT
CTTCTATGCATGAATTTATGCCATGAATTGATGATCGAGTTCGTTGATGGTAAAAAACTC
TATCTAGGAACAAGCCCTGATGAAGAATGCATTATGGAATTTTGCTTAAATACAGGAATA
TATTTAGATAGTATTGATGAACATAAAGTTATGACTATTATAGATTCTATCAATGGAAGA
ACCATACAATTTAAGCTTATTGCTATTCATGAGTATCGCTCAGAGTTAAGGAAAATGTCA
GTTCTAGTGTAGAATCTATAGACAAAGCAATATAAAATATATTAAAAAGGAGCTATGAAT
ACAATTTTCGACATTTGTTCAGAAGATTAATCTTTTAAAAAGGTGAAAGTTGAGGAGCAT
CTTAATGATTACGCAAACAACATGCTCAGAACTCTTTGTCTTTCTTATAAAAACCTAACT
GAAAAAGAAGTTTCTGATTTTTTGCAAAAGAAAAATGAAGAACTAAGTAAAGGAAACCTA
AATATCTAAGATATAAATGATTAAGTTTTTTCTTTAATTGAAAAAAATCACATTTTGATT
GGTGGAACTGGTGTGAATGATGAATTCGCTGACCAAGTAGTTTCAACACTTGCTAATCTA
AAGAAAGCAGGAATAAAAATCTGGATGATCACTGGAGACAAAAAAGAAACAGCGCTTAGC
ATTGGAATAAAATCCAACATAGTAGAAAAAGATGGTGACTTACAAGTAATTGAAGAAGGA
GTTGAAAATGGGTAAAATGATAATTTTACTATTGAGTAGCTTAAAAAATATAAAAAATAA
TTGTAAGATTAAAAAAAACTCAGCATTGGTATTTCTGGATTAACTTATCATAATATCCAC
ATTTCATAGAATGCAGAGCTTATTGAAAACTTCAATTTTGTCATGAAAAATGCTGATTCA
GTGATAGCCTTCCATTTCACTCCTATTCAGAAAAAGCAATTAGTTGATTTAGTCCATTAA
ATAAGTCCAGGATAGTGCGTTCTATCGATTGGCGATGGTGCTAATGACATCAATATGATC
TAAGCAGCTAACGTAGGAATAGGAATTCGTGGTAAAGAGGGAAGAGAAGCAGCTAAGGCT
TCTGATTTCTCTCTCGCAGAATTCAAACATTTAAATAGATTATTGCTATACACTGGCTAA
GAAGCTTACAGAAAAAATAGTTACCTAATATTCTTTAACTTTTATAAAAATTAAGCTTGG
AATTTAGTTTACTTTTGGTTTAATTTTTATGCTGGTTAGAGTGCCCAATATGTTTATGAT
TAGTGGATGACATAATTTTTTAATTTGTTCTATGTCTCTCTTCCTATTATATTATATGCT
CTTTTCGATGAAATGCATCCTTCAAACGAGTTCTTTTAACCAATCTAAACAAGAAAGAAT
GTTTTAGAGTCAAGGCCCCAAGATTACAAACACCTTACTAACAACCTTATCTTTCAACAA
AAAAACTTTTGGAGTTGGTTTTTCTACGGTTCCTTGCATTCCCTCATAATTATGTTTCTA
TCATTTTTAAGTGTTGGTGAATTCTCTGATAAAAATGGTAAATAAACAAACTTATTTTAC
TAAGGTATGCTAGCTTATACTTGTTGTGTTATTTTAGGAAACCTAAAAGTTTAGTAATTA
CATAGAACACATCACTTTGTTACTTTGTTTTTTATTTATGGTAGCATTGGTTTTTATTTT
ATGAATCTCTACATAGCAAATAAAATAACTACCTTAGATTGTTATGGAGTTATAAATGGC
TTATTCCGTTAAGCAAATACATATTTTGCAATAATGATTATGATTATGATAACTTATGGA
ATTGATTCTGCGTATGAAATATTTAATAAATCAAGAAATAATGCAGATTAGCAATAAAAC
ACCTAATTTTCTCTACAGATGCAAGTCTATCAAGGTTAGAAAGAAAACAATATAATTGTT
TATGATAAATCATCATAATAAGGTTCAGATTAAAATTGCATAGAAGAAAAAGCTAAAAAA
GACTATGATAGCTCTTCTGCAGGAGATATTAACAAAAATCTTCTAATTTATCCATTAAAA
GTTTAAATAAAAGATAATATACTACATGATAATTTAGCTGGAAGTAATTATTAATTAGAA
GAAGACTAACCCTATGATAACGAAGTATCTAACAAAAATAAGAAAAAATAAGTATTATCT
TAGGCTCCCTTATAAAACAAGTAGGCTTCTCCATCTTTGTTAATTTAAAAAGCTGATAAA
AAATGA

>TTHERM_01359440(gene)
AGTTCTTTGAACTTAACTAAATTTAGTATACTTAAAAATATTCAGTCATATGTAGATTTA
TTAAGTCGATAAGGTAAATAAGATCCAAAATTCTTATGAGAATGCAATAGAAAAGCCATA
TCTATACTGCTTTAAAAAGAAAGTAGCAAGAAAGTAGGAACTTAGGTCAGTTTACGCAGG
AATACCTGATAATTAGGTTTGCAATAATAGGATTTAGACATCAAAATACAATTATTTAAC
CTTCATTCCTAAGAATTTACTAGTTTAGTTTAGCAAACTCGCAAATATATACTTTATTAT
TATTGGTATTTGTCAAATCATACCTTAAATTACTACTACTGATGGAAAGCCTCTCGTTTA
TACTCCTTTAGGCATAATTATTTTTATAAGTATGGTAAAGGATTTTATCGAAGATAGAAA
AAGGAGAAAACAAGATGAATATGAAAATAAATCTTTAACAAACAGGTTTAATGCTTCGTC
CGGGGAATTTGAAAAAGTAGCATGGGAAGAACTTACAATTGGCGATATTATTAAAGTTGA
CTTAAATGAGCGATTTCCTGCTGACATTTTGATTCTTTCTACTACTAATCAATATGGAAA
TTGTTATGTTGAGACCAAAAATTTAGATGGAGAAACAAATTTAAAGCTGAGACAGAGTTG
TGCATCTCTCATTTTTACTGATGAAAATGCTGTTAAGAATGTAAACAATATTGGGAGATT
TTAATTTTAATATGAAGACCCAAATTATCGCATACACAGTTTCAATGGAATAATGATGGA
TGAACAAGAGAAAGATCCTTCAAAAAGCAAATATCCTCTTTCTTTGTAAAATATATGCTT
GAGAGGATGCACTCTTAAACGTACTCACTCGATTACAGCTGTTGTTATATATTCTGGACA
CGATTGCAAGTCTTTGAAATATGCCTAAAGAGGACACTATAAATTTGGCACAGTTGAAAA
GATGATGAACAAAATGGTTTTTTATATTTTCTTGATCCTTATATTAATAAGCATATTCTG
TGCTGCTTATTATGTGATTTGGTATAGCTACAAAAAAGACGAACTTACTTACCTTCATAT
AGGAGAACATGACATTGAGTCTTACCCTGCAGGAGATTTCTTTCTCAGAATTCCAATGTG
GGTTTTACTCCTAAGTAACTTTGTTCCCATATCGCTTCTAGTAACTCTTGAAATTGTGAA
GTATCTCCAAGGATAGCTGTTAACAAGAGACAAAAATTTTGTAAATAAATTAAGTGACGA
ACTAGTAGAAGTAAATAGTAGTAATTTGATAGATTAGCTTGGACAAGTCAGGTACATCCT
CACTGATAAAACAGGTACGTTGACTGGAAATGTTATGAAATTCAAAGCATTATCTGTCAA
TAGCAACTCTTACGAGCATACTGCATATGACGATAATGGAATTCTTAATAGTACAAAGTT
GCTTGAGTAATTAAAGGATTCATCAGAAAATCAACTTGAATATGAAGCTCTTCTATGCAT
GAATTTATGCCATGAATTGATGATCGAGTTCGTTGATGGTAAAAAACTCTATCTAGGAAC
AAGCCCTGATGAAGAATGCATTATGGAATTTTGCTTAAATACAGGAATATATTTAGATAG
TATTGATGAACATAAAGTTATGACTATTATAGATTCTATCAATGGAAGAACCATACAATT
TAAGCTTATTGCTATTCATGAGTATCGCTCAGAGTTAAGGAAAATGTCAGTTCTAGTGTA
GAATCTATAGACAAAGCAATATAAAATATATTAAAAAGGAGCTATGAATACAATTTTCGA
CATTTGTTCAGAAGATTAATCTTTTAAAAAGGTGAAAGTTGAGGAGCATCTTAATGATTA
CGCAAACAACATGCTCAGAACTCTTTGTCTTTCTTATAAAAACCTAACTGAAAAAGAAGT
TTCTGATTTTTTGCAAAAGAAAAATGAAGAACTAAGTAAAGGAAACCTAAATATCTAAGA
TATAAATGATTAAGTTTTTTCTTTAATTGAAAAAAATCACATTTTGATTGGTGGAACTGG
TGTGAATGATGAATTCGCTGACCAAGTAGTTTCAACACTTGCTAATCTAAAGAAAGCAGG
AATAAAAATCTGGATGATCACTGGAGACAAAAAAGAAACAGCGCTTAGCATTGGAATAAA
ATCCAACATAGTAGAAAAAGATGGTGACTTACAAGTAATTGAAGAAGGAGTTGAAAATGG
GTAAAATGATAATTTTACTATTGAGTAGCTTAAAAAATATAAAAAATAATTGTAAGATTA
AAAAAAACTCAGCATTGGTATTTCTGGATTAACTTATCATAATATCCACATTTCATAGAA
TGCAGAGCTTATTGAAAACTTCAATTTTGTCATGAAAAATGCTGATTCAGTGATAGCCTT
CCATTTCACTCCTATTCAGAAAAAGCAATTAGTTGATTTAGTCCATTAAATAAGTCCAGG
ATAGTGCGTTCTATCGATTGGCGATGGTGCTAATGACATCAATATGATCTAAGCAGCTAA
CGTAGGAATAGGAATTCGTGGTAAAGAGGGAAGAGAAGCAGCTAAGGCTTCTGATTTCTC
TCTCGCAGAATTCAAACATTTAAATAGATTATTGCTATACACTGGCTAAGAAGCTTACAG
AAAAAATAGTTACCTAATATTCTTTAACTTTTATAAAAATTAAGCTTGGAATTTAGTTTA
CTTTTGGTTTAATTTTTATGCTGGTTAGAGTGCCCAATATGTTTATGATTAGTGGATGAC
ATAATTTTTTAATTTGTTCTATGTCTCTCTTCCTATTATATTATATGCTCTTTTCGATGA
AATGCATCCTTCAAACGAGTTCTTTTAACCAATCTAAACAAGAAAGAATGTTTTAGAGTC
AAGGCCCCAAGATTACAAACACCTTACTAACAACCTTATCTTTCAACAAAAAAACTTTTG
GAGTTGGTTTTTCTACGGTTCCTTGCATTCCCTCATAATTATGTTTCTATCATTTTTAAG
TGTTGGTGAATTCTCTGATAAAAATGGTAAATAAACAAACTTATTTTACTAAGGTATGCT
AGCTTATACTTGTTGTGTTATTTTAGGAAACCTAAAAGTTTAGTAATTACATAGAACACA
TCACTTTGTTACTTTGTTTTTTATTTATGGTAGCATTGGTTTTTATTTTATGAATCTCTA
CATAGCAAATAAAATAACTACCTTAGATTGTTATGGAGTTATAAATGGCTTATTCCGTTA
AGCAAATACATATTTTGCAATAATGATTATGATTATGATAACTTATGGAATTGATTCTGC
GTATGAAATATTTAATAAATCAAGAAATAATGCAGATTAGCAATAAAACACCTAATTTTC
TCTACAGATGCAAGTCTATCAAGGTTAGAAAGAAAACAATATAATTGTTTATGATAAATC
ATCATAATAAGGTTCAGATTAAAATTGCATAGAAGAAAAAGCTAAAAAAGACTATGATAG
CTCTTCTGCAGGAGATATTAACAAAAATCTTCTAATTTATCCATTAAAAGTTTAAATAAA
AGATAATATACTACATGATAATTTAGCTGGAAGTAATTATTAATTAGAAGAAGACTAACC
CTATGATAACGAAGTATCTAACAAAAATAAGAAAAAATAAGTATTATCTTAGGCTCCCTT
ATAAAACAAGTAGGCTTCTCCATCTTTGTTAATTTAAAAAGCTGATAAAAAATGAATTAA
TTTATTGAATTTTTTATAAAACATCCATATTATATTTGTTACTCATAAATATATTTTTTA
TTTTAATTTATAAATTTTA

>TTHERM_01359440(protein)
MQIYQVDKVNKIQNSYENAIEKPYLYCFKKKVARKQELRSVYAGIPDNQVCNNRIQTSKY
NYLTFIPKNLLVQFSKLANIYFIIIGICQIIPQITTTDGKPLVYTPLGIIIFISMVKDFI
EDRKRRKQDEYENKSLTNRFNASSGEFEKVAWEELTIGDIIKVDLNERFPADILILSTTN
QYGNCYVETKNLDGETNLKLRQSCASLIFTDENAVKNVNNIGRFQFQYEDPNYRIHSFNG
IMMDEQEKDPSKSKYPLSLQNICLRGCTLKRTHSITAVVIYSGHDCKSLKYAQRGHYKFG
TVEKMMNKMVFYIFLILILISIFCAAYYVIWYSYKKDELTYLHIGEHDIESYPAGDFFLR
IPMWVLLLSNFVPISLLVTLEIVKYLQGQLLTRDKNFVNKLSDELVEVNSSNLIDQLGQV
RYILTDKTGTLTGNVMKFKALSVNSNSYEHTAYDDNGILNSTKLLEQLKDSSENQLEYEA
LLCMNLCHELMIEFVDGKKLYLGTSPDEECIMEFCLNTGIYLDSIDEHKVMTIIDSINGR
TIQFKLIAIHEYRSELRKMSVLVQNLQTKQYKIYQKGAMNTIFDICSEDQSFKKVKVEEH
LNDYANNMLRTLCLSYKNLTEKEVSDFLQKKNEELSKGNLNIQDINDQVFSLIEKNHILI
GGTGVNDEFADQVVSTLANLKKAGIKIWMITGDKKETALSIGIKSNIVEKDGDLQVIEEG
VENGQNDNFTIEQLKKYKKQLQDQKKLSIGISGLTYHNIHISQNAELIENFNFVMKNADS
VIAFHFTPIQKKQLVDLVHQISPGQCVLSIGDGANDINMIQAANVGIGIRGKEGREAAKA
SDFSLAEFKHLNRLLLYTGQEAYRKNSYLIFFNFYKNQAWNLVYFWFNFYAGQSAQYVYD
QWMTQFFNLFYVSLPIILYALFDEMHPSNEFFQPIQTRKNVLESRPQDYKHLTNNLIFQQ
KNFWSWFFYGSLHSLIIMFLSFLSVGEFSDKNGKQTNLFYQGMLAYTCCVILGNLKVQQL
HRTHHFVTLFFIYGSIGFYFMNLYIANKITTLDCYGVINGLFRQANTYFAIMIMIMITYG
IDSAYEIFNKSRNNADQQQNTQFSLQMQVYQGQKENNIIVYDKSSQQGSDQNCIEEKAKK
DYDSSSAGDINKNLLIYPLKVQIKDNILHDNLAGSNYQLEEDQPYDNEVSNKNKKKQVLS
QAPLQNKQASPSLLIQKADKK