Identifiers and Description

Gene Model Identifier

TTHERM_00526270

Standard Name

COI3 (COnjugation-Induced 3)

Aliases

PreTt06365 | 66.m00164 | 3722.m00022 | ATG4.1

Description

COI3 peptidase family C54 protein; TTHERM_00526270 consists of two genes: COI3 and a gene encoding peptidase family C54 containing protein; hypothetical protein

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Biological Process

• autophagy (ISS) | GO:0006914

Domains

No Data fetched for Domains

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

No Data fetched for Homologs

General Information

No.	Gene Name(s)	Paragraph Text
2317	JUB1, JUB2, COI6, COI3, JUB4, HPL2	This protein co-localizes with Pdd1p in heterochromatin body in the new macronucleus.

Associated Literature

1. Ref:26688337: Kataoka K, Mochizuki K (2015) Phosphorylation of an HP1-like Protein Regulates Heterochromatin Body Assembly for DNA Elimination. Developmental cell 35(6):775-88
2. Ref:25588944: Woehrer SL, Aronica L, Suhren JH, Busch CJ, Noto T, Mochizuki K (2015) A Tetrahymena Hsp90 co-chaperone promotes siRNA loading by ATP-dependent and ATP-independent mechanisms. The EMBO journal 34(4):559-77
3. Ref:22366125: Liu ML, Yao MC (2012) Role of ATG8 and autophagy in programmed nuclear degradation in Tetrahymena thermophila. Eukaryotic cell 11(4):494-506

Sequences

>TTHERM_00526270(coding)
ATGGTCTTAATTGCAGTATCTTATTTGCTTTGCAGAAGTACTCAAATTTATAGATAGTTA
TTAGAATTTAGAGATATATATATACTTTGTAAAACTTGGATTATTTATAAAATCTAATTT
AATAAATCTACTAATTCAGTCGCATTAGCAAATATTTTAGAGATGTCTTAGTCTAAAGAA
ATTGATTATTTCAAATCCATAAAGCTATCAATGTCCAAAGCTTTTTCTGAAGATGGAAGA
CGTGTTTCTACTAATAATATTACTGAAGGTATTATGAGCTACGGGATGTAGCAGATATAC
AGATTTAATAAATGGGGAACTTCATGTAAAACAATAGATCTTAAGGTTGATATCCCATCT
TTCATATTAGGAAATGATTTAACACCGCAAAGAGTAAAGTTAGTTTAGGATAAAAGTAGA
GTTTTACAAGATGATGGCAATTAGAATAAATACAGAATGCTTATGTTGTCTAATTCAAGT
GATATTAGAGTAGACACAGAACCAAAATAAGAAGAAATAATATCTAAAGAAACATACTAA
ACATAAGAGACTTCTGGATAAGACTATGATGATGAAGATTATCAAGAAACAGAAAAATAA
ATGAAAGAAAAATCAAAATAAATACTTTAAATTTACTAAAACACAATCCTTTTTACATAT
AGAAAAAACTTCTATCCTTTACTAAAAGACAAAATAAATGACCCACAAAAGAATTAAACT
TCAGATGCGGGATGGGGCTGTATGATTCGAGCTGGATAAATGATTTTTGCTTAGACTATA
AAGAGACATTTAAAAAAAACAGACTATATAGAATAGCATTAGCTAATAAACATTATAATA
GGCTTTTTAGAAGAAGAGGAAGTACAAGAAGGAGGAAAAGGATATATTTTTAATTAATAA
AGTTATATATAAGATAGAATTCGTCCTTATAGCATACATCAAATTACTAATAGAGCATTT
TGTAAATATAAAATACAACCAGGGTAATGGTACACTCCAAATTAAATCGCCATCATATTA
AAGGAGCTCCATAAAAAAAATAAAATTAAAGGAACTGAAAATTTAAAAATAGATGTTCAT
AGTAGTGATAAACCAATTATATTTGAAAAAATCTTGTAAACACTTTTGGGGCGTTAAGGC
AAAATTAATTTAAACTGCAACCATGAAAATTAGTAATCAAGAAACTCAATAAATCAAGAT
TAAGATGATTCGTTTGAAAAAATCATGCCTCCTAACTAGCAAGAAATAGAAGAGTTTTCA
AGCTAGTATGAAGAAAGCAAGGAAGATTAGACAGATAATTTATGTTGTAAAGACTGCTTT
AAAACAGACAACAAGCTGTTTCTCCTTCTACCATGCAGACTAGGATTAGATGAAATCAGC
CCAATTCATATAGAAATCCTTAAAAAATTATTGTCTCTCAAACAATCTGTTGGAATGATA
GGAGGTAAACCAAACAAAGCTCACTACTTTTTAGGATTTGTAGGAGATGATTTATTATAT
TTAGATCCTCATTATATCAAAGAATGTGTTAGAAAAGAAGATCTAATGGAAAATATTTCT
TCTTATTTCGAAGAAGATGTTTTTAAAATGCCAATAAATAAAATTAGTACCTCATTGGTG
TTTGGATTTTATTTTAGTGGCGTTGATGAGCTAAATAAATTCTATAAATTTTTAAGATAA
CTAGAAAAAGAATATAAAGATGATTTTTTCCTTGTAATTGAAAAATAAACTCCTTCTTAT
GCAATGTCGAATATCTCTGAGATAAAAAAGTTGACTAAGTAAATAAAGATTACTTAAAAA
GATAATTAAAATCTTTTGGAATAATAATTTGAGAATTATGATGGATCAGTAGGTGATGAC
TTTGATGAAGATGATGATACAAGCTATGATGAATAAGAATGCTATGAAGACAAATTAGAT
GAATTCGATTAATATAATAACTTAGAAGAATCAGACTATTCTTAAAAGCTTAAACAATAA
ACTAATTTAAAAAACTACAGTGACCCATTTGGTACTGAAAGCCATTCCGAAAACCAATTA
AAATATGGAAAATTGGCTAATCATGAGCTACCAATAAGAAACCAGATCTAAAAAAAATAA
AGTGAAGAGGAATTAAAAAATCTTGTAAATTTAATTTAATTATAGTAACAAAATCAGCAG
ATAAGTAACTTATTATAAAATCAGAATTGTATTTGA

>TTHERM_00526270(gene)
ATGGTCTTAATTGCAGTATCTTATTTGCTTTGCAGAAGTACTCAAATTTATAGATAGTTA
TTAGAATTTAGAGATATATATATACTTTGTAAAACTTGGATTATTTATAAAATCTAATTT
AATAAATCTACTAATTCAGTCGCATTAGCAAATATTTTAGAGATGTCTTAGTCTAAAGAA
ATTGATTATTTCAAATCCATAAAGCTATCAATGTCCAAAGCTTTTTCTGAAGATGGAAGA
CGTGTTTCTACTAATAATATTACTGAAGGTATTATGAGCTACGGGATGTAGCAGATATAC
AGATTTAATAAATGGGGAACTTCATGTAAAACAATAGATCTTAAGGTTGATATCCCATCT
TTCATATTAGGAAATGATTTAACACCGCAAAGAGTAAAGTTAGTTTAGGATAAAAGTAGA
GTTTTACAAGATGATGGCAATTAGAATAAATACAGAATGCTTATGTTGTCTAATTCAAGT
GATATTAGAGTAGACACAGAACCAAAATAAGAAGAAATAATATCTAAAGAAACATACTAA
ACATAAGAGACTTCTGGATAAGACTATGATGATGAAGATTATCAAGAAACAGAAAAATAA
ATGAAAGAAAAATCAAAATAAATACTTTAAATTTACTAAAACACAATCCTTTTTACATAT
AGAAAAAACTTCTATCCTTTACTAAAAGACAAAATAAATGACCCACAAAAGAATTAAACT
TCAGATGCGGGATGGGGCTGTATGATTCGAGCTGGATAAATGATTTTTGCTTAGACTATA
AAGAGACATTTAAAAAAAACAGACTATATAGAATAGCATTAGCTAATAAACATTATAATA
GGCTTTTTAGAAGAAGAGGAAGTACAAGAAGGAGGAAAAGGATATATTTTTAATTAATAA
AGTTATATATAAGATAGAATTCGTCCTTATAGCATACATCAAATTACTAATAGAGCATTT
TGTAAATATAAAATACAACCAGGGTAATGGTACACTCCAAATTAAATCGCCATCATATTA
AAGGAGCTCCATAAAAAAAATAAAATTAAAGGAACTGAAAATTTAAAAATAGATGTTCAT
AGTAGTGATAAACCAATTATATTTGAAAAAATCTTGTAAACACTTTTGGGGCGTTAAGGC
AAAATTAATTTAAACTGCAACCATGAAAATTAGTAATCAAGAAACTCAATAAATCAAGAT
TAAGATGATTCGTTTGAAAAAATCATGCCTCCTAACTAGCAAGAAATAGAAGAGTTTTCA
AGCTAGTATGAAGAAAGCAAGGAAGATTAGACAGATAATTTATGTTGTAAAGACTGCTTT
AAAACAGACAACAAGCTGTTTCTCCTTCTACCATGCAGACTAGGATTAGATGAAATCAGC
CCAATTCATATAGAAATCCTTAAAAAATTATTGTCTCTCAAACAATCTGTTGGAATGATA
GGAGGTAAACCAAACAAAGCTCACTACTTTTTAGGATTTGTAGGAGATGATTTATTATAT
TTAGATCCTCATTATATCAAAGAATGTGTTAGAAAAGAAGATCTAATGGAAAATATTTCT
TCTTATTTCGAAGAAGATGTTTTTAAAATGCCAATAAATAAAATTAGTACCTCATTGGTG
TTTGGATTTTATTTTAGTGGCGTTGATGAGCTAAATAAATTCTATAAATTTTTAAGATAA
CTAGAAAAAGAATATAAAGATGATTTTTTCCTTGTAATTGAAAAATAAACTCCTTCTTAT
GCAATGTCGAATATCTCTGAGATAAAAAAGTTGACTAAGTAAATAAAGATTACTTAAAAA
GATAATTAAAATCTTTTGGAATAATAATTTGAGAATTATGATGGATCAGTAGGTGATGAC
TTTGATGAAGATGATGATACAAGCTATGATGAATAAGAATGCTATGAAGACAAATTAGAT
GAATTCGATTAATATAATAACTTAGAAGAATCAGACTATTCTTAAAAGCTTAAACAATAA
ACTAATTTAAAAAACTACAGTGACCCATTTGGTACTGAAAGCCATTCCGAAAACCAATTA
AAATATGGAAAATTGGCTAATCATGAGCTACCAATAAGAAACCAGATCTAAAAAAAATAA
AGTGAAGAGGAATTAAAAAATCTTGTAAATTTAATTTAATTATAGTAACAAAATCAGCAG
ATAAGTAACTTATTATAAAATCAGAATTGTATTTGAATAATTATCTAAAAGAAATACAAT
CAATCAACTTACCAAATAGATAAATATATTTCTAAGATCTACTTAAAAATTATTAATTAA
TTTATAATATTAAATCATATAAATAAATTATAAAAGTAATATAAAAGATAGTTATAAATA
TTGTGATTTGCTCAATAAATTGTCAGTGTAATTCTATTTATGATTATGCTGATTTTTCTC
GAAACTTTTAATGTTTCGTATATAAAGATAGAGTAGGTCAAATTAAAAACACAAAAAATA
AAAAAATAAATAAGCAGTTTTTAAATACAAAAGAAAGTATTTTAAATATGTTAATTAAAG
CTACTTACTTATTTTTTTTGTAATTTAATATTAAGCATTATATTTTATTGTTATATATAT
ACTTTTATTTTAATTTCATCTTTTTAAAAGATATTTTAATCA

>TTHERM_00526270(protein)
MVLIAVSYLLCRSTQIYRQLLEFRDIYILCKTWIIYKIQFNKSTNSVALANILEMSQSKE
IDYFKSIKLSMSKAFSEDGRRVSTNNITEGIMSYGMQQIYRFNKWGTSCKTIDLKVDIPS
FILGNDLTPQRVKLVQDKSRVLQDDGNQNKYRMLMLSNSSDIRVDTEPKQEEIISKETYQ
TQETSGQDYDDEDYQETEKQMKEKSKQILQIYQNTILFTYRKNFYPLLKDKINDPQKNQT
SDAGWGCMIRAGQMIFAQTIKRHLKKTDYIEQHQLINIIIGFLEEEEVQEGGKGYIFNQQ
SYIQDRIRPYSIHQITNRAFCKYKIQPGQWYTPNQIAIILKELHKKNKIKGTENLKIDVH
SSDKPIIFEKILQTLLGRQGKINLNCNHENQQSRNSINQDQDDSFEKIMPPNQQEIEEFS
SQYEESKEDQTDNLCCKDCFKTDNKLFLLLPCRLGLDEISPIHIEILKKLLSLKQSVGMI
GGKPNKAHYFLGFVGDDLLYLDPHYIKECVRKEDLMENISSYFEEDVFKMPINKISTSLV
FGFYFSGVDELNKFYKFLRQLEKEYKDDFFLVIEKQTPSYAMSNISEIKKLTKQIKITQK
DNQNLLEQQFENYDGSVGDDFDEDDDTSYDEQECYEDKLDEFDQYNNLEESDYSQKLKQQ
TNLKNYSDPFGTESHSENQLKYGKLANHELPIRNQIQKKQSEEELKNLVNLIQLQQQNQQ
ISNLLQNQNCI