Identifiers and Description

Gene Model Identifier

TTHERM_00194050

Standard Name

MYO4 (MYOsin )

Aliases

PreTt06689 | 16.m00345

Description

MYO4 myosin head protein; Myosin heavy chain; member of proposed myosin Class XX, distinct from previously defined myosin classes; contains predicted coiled-coil and myosin tail homology (MyTH4) domains; MyTH4 domain

Genome Browser (Macronucleus)

Full Screen View

No Genome Browser Data Present

Genome Browser (Micronucleus)

Full Screen View

No Genome Browser Data Present

External Links

• Uniprot
• Alphafold

Gene Ontology Annotations

Cellular Component

• chloroplast ribosome (IEA) | GO:0043253
• EGFR-Grb2-Sos complex (IEA) | GO:0070620
• heterochromatin domain (IEA) | GO:1990343
• M band (IEA) | GO:0031430
• obsolete integral component of mitochondrial membrane (IEA) | GO:0032592
• obsolete transforming growth factor beta1-type II receptor complex (IEA) | GO:0070020
• protein storage vacuole (IEA) | GO:0000326
• synaptobrevin 2-SNAP-25-syntaxin-3 complex (IEA) | GO:0070046

Molecular Function

• 11-deoxycorticosterone binding (IEA) | GO:1903878
• 17alpha-hydroxyprogesterone binding (IEA) | GO:1903880
• 2-octaprenyl-6-methoxyphenol hydroxylase activity (IEA) | GO:0008681
• alpha-humulene synthase activity (IEA) | GO:0080017
• arsenate reductase (glutaredoxin) activity (IEA) | GO:0008794
• cAMP-dependent protein kinase regulator activity (IEA) | GO:0008603
• corticotrophin-releasing factor receptor activity (IEA) | GO:0015056
• G protein-coupled serotonin receptor binding (IEA) | GO:0031821
• glucuronate-2-sulfatase activity (IEA) | GO:0015024
• GTP:coenzyme F420 guanyltransferase activity (IEA) | GO:0052754
• Janus kinase activity (IEA) | GO:0004718
• kappa-type opioid receptor binding (IEA) | GO:0031851
• lysine:proton symporter activity (IEA) | GO:0015493
• methane monooxygenase [NAD(P)H] activity (IEA) | GO:0015049
• microtubule severing ATPase activity (IEA) | GO:0008568
• minus-end directed microfilament motor activity (IEA) | GO:0060001
• mitochondrial heavy strand promoter sense binding (IEA) | GO:0070364
• obsolete cation:cation antiporter activity (IEA) | GO:0015491
• obsolete GPI-anchored membrane-bound receptor (IEA) | GO:0015025
• obsolete phosphatidylinositol 3-kinase, class I, catalyst activity (IEA) | GO:0015072
• obsolete protein tagging activity (IEA) | GO:0008638
• obsolete RNA polymerase I transcription regulator recruiting activity (IEA) | GO:0001186
• obsolete sodium-transporting two-sector ATPase activity (IEA) | GO:0015443
• obsolete tubulin GTPase activity (IEA) | GO:0008550
• obsolete type II protein secretor activity (IEA) | GO:0015447
• phosphatidylinositol-3-phosphate binding (IEA) | GO:0032266
• phosphatidylserine decarboxylase activity (IEA) | GO:0004609
• protein tyrosine kinase activity (IEA) | GO:0004713
• Pup ligase activity (IEA) | GO:0061664
• RNA 2',3'-cyclic 3'-phosphodiesterase activity (IEA) | GO:0008664
• silver ion transmembrane transporter activity (IEA) | GO:0015080
• sphingomyelin phosphodiesterase activity (IEA) | GO:0004767
• telomerase RNA binding (IEA) | GO:0070034
• type 4 neuropeptide Y receptor binding (IEA) | GO:0031844
• UFM1 ligase activity (IEA) | GO:0061666

Biological Process

• (R)-mevalonic acid biosynthetic process (IEA) | GO:1901737
• 3-keto-sphinganine metabolic process (IEA) | GO:0006666
• 5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate biosynthetic process (IEA) | GO:1901949
• activation of MAPKKK activity involved in osmosensory signaling pathway (IEA) | GO:0000167
• alkaloid biosynthetic process (IEA) | GO:0009821
• carotenoid metabolic process (IEA) | GO:0016116
• cellular response to dimethyl sulfoxide (IEA) | GO:1904620
• cellular response to dopamine (IEA) | GO:1903351
• cellular response to hydroxyurea (IEA) | GO:0072711
• copper ion homeostasis (IEA) | GO:0055070
• detection of stimulus involved in sensory perception of pain (IEA) | GO:0062149
• embryonic process involved in female pregnancy (IEA) | GO:0060136
• establishment of bipolar cell polarity (IEA) | GO:0061171
• evoked neurotransmitter secretion (IEA) | GO:0061670
• fat cell proliferation (IEA) | GO:0070341
• fatty acid transmembrane transport (IEA) | GO:1902001
• fibroblast growth factor receptor signaling pathway (IEA) | GO:0008543
• flower phyllotactic patterning (IEA) | GO:0060773
• gibberellic acid mediated signaling pathway (IEA) | GO:0009740
• glycolytic process from glycerol (IEA) | GO:0061613
• GMP salvage (IEA) | GO:0032263
• hair cycle process (IEA) | GO:0022405
• heme A biosynthetic process (IEA) | GO:0006784
• heme biosynthetic process (IEA) | GO:0006783
• high density lipoprotein particle mediated signaling (IEA) | GO:0055097
• high-affinity hexose transport (IEA) | GO:0008646
• IMP salvage (IEA) | GO:0032264
• induction of apoptosis by extracellular signals (IEA) | GO:0008624
• interleukin-19 production (IEA) | GO:0032622
• interleukin-2 production (IEA) | GO:0032623
• iodide transmembrane transport (IEA) | GO:1904200
• leaf phyllotactic patterning (IEA) | GO:0060772
• low-density lipoprotein particle mediated signaling (IEA) | GO:0055096
• lung growth (IEA) | GO:0060437
• Malpighian tubule tip cell differentiation (IEA) | GO:0061382
• mannosyl-inositol phosphorylceramide metabolic process (IEA) | GO:0006675
• mast cell differentiation (IEA) | GO:0060374
• maternal process involved in parturition (IEA) | GO:0060137
• mesonephric glomerular mesangial cell fate commitment (IEA) | GO:0061264
• mesonephric interstitial fibroblast differentiation (IEA) | GO:0061266
• mitochondrial membrane organization (IEA) | GO:0007006
• mitotic cytokinetic cell separation (IEA) | GO:1902409
• mitotic nuclear division (IEA) | GO:0007067
• modulation by organism of innate immune response in other organism involved in symbiotic interaction (IEA) | GO:0052306
• negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process (IEA) | GO:1902642
• negative regulation of axon guidance (IEA) | GO:1902668
• negative regulation of cellular glucuronidation (IEA) | GO:2001030
• negative regulation of chemokine-mediated signaling pathway (IEA) | GO:0070100
• negative regulation of filamentous growth (IEA) | GO:0060258
• negative regulation of interleukin-1 production (IEA) | GO:0032692
• negative regulation of interleukin-17-mediated signaling pathway (IEA) | GO:1903882
• negative regulation of interleukin-4-mediated signaling pathway (IEA) | GO:1902215
• negative regulation of L-glutamine biosynthetic process (IEA) | GO:0062133
• negative regulation of PERK-mediated unfolded protein response (IEA) | GO:1903898
• negative regulation of phospholipid translocation (IEA) | GO:0061093
• negative regulation of postsynaptic membrane organization (IEA) | GO:1901627
• neosartoricin metabolic process (IEA) | GO:1902048
• neutral lipid metabolic process (IEA) | GO:0006638
• nitrate transmembrane transport (IEA) | GO:0015706
• obsolete activation of MAPK activity (IEA) | GO:0000187
• obsolete di-, tri-valent inorganic cation homeostasis (IEA) | GO:0055066
• obsolete energy taxis in environment of other organism involved in symbiotic interaction (IEA) | GO:0052215
• obsolete histone succinylation (IEA) | GO:0106077
• obsolete loss of asymmetric budding (IEA) | GO:0007122
• obsolete metal ion homeostasis (IEA) | GO:0055065
• obsolete modulation of catalytic activity in other organism involved in symbiotic interaction (IEA) | GO:0052203
• obsolete modulation of molecular function in other organism involved in symbiotic interaction (IEA) | GO:0052205
• obsolete modulation of peptidase activity in other organism involved in symbiotic interaction (IEA) | GO:0052198
• obsolete mRNA endonucleolytic cleavage involved in unfolded protein response (IEA) | GO:0070055
• obsolete multi-organism cellular localization (IEA) | GO:1902581
• obsolete negative regulation by host of symbiont defense response (IEA) | GO:0052196
• obsolete negative regulation of histone H3-K18 acetylation (IEA) | GO:1902030
• obsolete negative regulation of L-leucine import (IEA) | GO:0060358
• obsolete positive regulation by host of symbiont defense response (IEA) | GO:0052197
• obsolete positive regulation of nucleic acid-templated transcription (IEA) | GO:1903508
• obsolete regulation of apurinic/apyrimidinic endodeoxyribonuclease activity (IEA) | GO:0052721
• obsolete regulation of nucleic acid-templated transcription (IEA) | GO:1903506
• obsolete response to lipoic acid (IEA) | GO:1990479
• obsolete response to long exposure to lithium ion (IEA) | GO:0043460
• obsolete telomere binding (IEA) | GO:0007003
• ommochrome biosynthetic process (IEA) | GO:0006727
• P granule disassembly (IEA) | GO:1903864
• peptidyl-lysine propionylation (IEA) | GO:0061921
• peripheral tolerance induction to nonself antigen (IEA) | GO:0002464
• phagocytosis (IEA) | GO:0006909
• photosynthesis, light harvesting in photosystem I (IEA) | GO:0009768
• photosynthetic NADP+ reduction (IEA) | GO:0009780
• phyllotactic patterning (IEA) | GO:0060771
• plant-type cell wall modification (IEA) | GO:0009827
• polyamine acetylation (IEA) | GO:0032917
• positive regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process (IEA) | GO:1902643
• positive regulation of actin binding (IEA) | GO:1904618
• positive regulation of ATF6-mediated unfolded protein response (IEA) | GO:1903893
• positive regulation of cell-cell adhesion (IEA) | GO:0022409
• positive regulation of double-strand break repair via nonhomologous end joining (IEA) | GO:2001034
• positive regulation of glutamate neurotransmitter secretion in response to membrane depolarization (IEA) | GO:0061646
• positive regulation of interleukin-4-mediated signaling pathway (IEA) | GO:1902216
• positive regulation of protein processing (IEA) | GO:0010954
• propan-2-ol biosynthetic process (IEA) | GO:1902640
• prostate induction (IEA) | GO:0060514
• protein K27-linked deubiquitination (IEA) | GO:1990167
• protein localization to nucleoplasm (IEA) | GO:1990173
• protein localization to old growing cell tip (IEA) | GO:1903858
• regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process (IEA) | GO:1902646
• regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process (IEA) | GO:1902641
• regulation of atrial cardiac muscle cell membrane repolarization (IEA) | GO:0060372
• regulation of cellular respiration (IEA) | GO:0043457
• regulation of chitin metabolic process (IEA) | GO:0032882
• regulation of cytokinin dehydrogenase activity (IEA) | GO:1903856
• regulation of dendrite extension (IEA) | GO:1903859
• regulation of flocculation (IEA) | GO:0060256
• regulation of frizzled signaling pathway (IEA) | GO:0008590
• regulation of interleukin-27-mediated signaling pathway (IEA) | GO:0070107
• regulation of pentose-phosphate shunt (IEA) | GO:0043456
• regulation of positive chemotaxis to cAMP by DIF-1 (IEA) | GO:0061120
• regulation of protein localization to cell cortex (IEA) | GO:1904776
• regulation of protein localization to cell division site (IEA) | GO:1901900
• regulation of Wnt signaling pathway, calcium modulating pathway (IEA) | GO:0008591
• response to high density lipoprotein particle (IEA) | GO:0055099
• response to iron(II) ion (IEA) | GO:0010040
• response to low-density lipoprotein particle stimulus (IEA) | GO:0055098
• response to methamphetamine hydrochloride (IEA) | GO:1904313
• response to oxygen radical (IEA) | GO:0000305
• response to reactive oxygen species (IEA) | GO:0000302
• semaphorin-plexin signaling pathway involved in outflow tract morphogenesis (IEA) | GO:0071527
• single-organism intracellular transport (IEA) | GO:1902582
• striated muscle myosin thick filament assembly (IEA) | GO:0071688
• T cell mediated immune response to tumor cell (IEA) | GO:0002424
• trabecula morphogenesis (IEA) | GO:0061383
• vacuolar acidification (IEA) | GO:0007035

Domains

• ( PF00063 ) Myosin head (motor domain)
• ( PF00784 ) MyTH4 domain

Gene Expression Profile

Vegetative Cell Cycle (Zhang et al., 2023)

GeneMania

No results were calculated for this gene in GeneMania.

Tetrahymena Stock Center

No Data fetched for Tetrahymena Stock Center

Homologs

No Data fetched for Homologs

General Information

No.	Gene Name(s)	Paragraph Text
2217	MYO10, MYO11, MYO1, MYO4, MYO9, MYO5, MYO12, MYO3, MYO13, MYO4a, MYO2	Proteins of the myosin superfamily are ATP-dependent molecular motors that travel unidirectionally along actin filaments. The myosin heavy chain proteins are comprised of three domains: a head (motor) domain responsible for ATP hydrolysis at the N-terminus, a neck (lever arm) region, and a C-terminal tail region. Thirteen predicted myosin heavy chain genes have been identified in the Tetrahymena genome and named MYO1-MYO13. A phylogenetic analysis comparing these predicted proteins with the 19 previously identified myosin classes suggests that Myo1p-Myo12p belong to a previously undescribed class of myosins. This new family, designated Class XX, does not include Myo13p, which did not branch with this class or any of the other classes in the analysis. The neck and tail regions of the Tetrahymena myosins include a variety of domains characterized in other myosin classes, with each protein containing one or more of the following domains: coiled-coil (which may support dimerization); IQ motif (binding sites for calmodulin or calmodulin-like proteins); FERM domain (Four-point-one protein, Ezrin, Radixin, Moesin homology); and MyTH4 domain (Myosin Tail Homology 4).

Associated Literature

1. Ref:16505385: Foth BJ, Goedecke MC, Soldati D (2006) New insights into myosin evolution and classification. Proceedings of the National Academy of Sciences of the United States of America 103(10):3681-6
2. Ref:15988740: Williams SA, Gavin RH (2005) Myosin genes in Tetrahymena. Cell motility and the cytoskeleton 61(4):237-43

Sequences

>TTHERM_00194050(coding)
ATGCTAGATATAAATACTACATGGATGATTCCGGACAGTGAGTGCTGGATTTAAGTAGGA
GAAGAAGATGCATAAACATAAACAATGTTTGTGAAAGCTAAAATAAAATAAAAACCCAGT
CTTTCAAACATTAATAAGAATAATGTTTAACAATGTTTTGCTGACATAAAAGATGTAGAA
GATAATCGATATGCTAATATAACAAAAGTTAAAATAAATTCAGTTTATTAAGTAAACTAA
GAAGTACCTTAAGGTTATAATGATATGGTAGAAATGGATCACTTGAATTAAGCAGAAATT
CTTATTAATTTATAAAGAAGATACGATTAAGATTTAATATTTACATTTATAGGTCCTACA
CTTGTAGTGATGAATCCTTACAAGTTAATTCCAAAGCATTTTTCAAATGAAACTCGTAAT
ATTTTTTCATAATAAGCAAAACACCAAGGCTACATCGATTATAAAAAAAATGATCCACAT
ACTTATGCTGTAGCTGCTTAATCATATTGTAAGCTTTTTGAGTAAAATAAAAATCAAGCC
ATAGTAATATCAGGTGAGTCAGGTGCAGGAAAGACTGAAAATGCCAAAATATGCATGTGT
TTTCTTACAGGATTAAGCGGATAAGATGCTGAAAGAAGACCTAGTATATAAAATAGTACT
TCTCCAGCTAATAAAAATAAAAATAATATTGAAGATAGAATTTTGGGATGCAACCCTATA
TTAGAGGCGTTTGGAAATGCAAAAACTGTTAGAAATGATAACAGCTCTCGTTTTGGAAAA
TTTGTATCGATTTAAGTAGGGAAAAAATCAAGAAAAATTAAAGGTGCTACAATTTAGAAC
TATTTACTAGAAAAGAGTCGTGTTACCACTCCTGGTCCTGGAGAGCGCGGTTACCACATA
TTTTATCACTTACTCTACTGCGGATAAAACTAACTTTTAGAAAATTTATAATTGGTAGGT
TAATATTCAAAACCACAAAATCTAAATTACTTAAAAGTTAGTAATTGTTATGAAGTATCA
ACTATAAATGACAATGCTCTGTTTAAAGAAGTTGTTGAGGCCTTTCATACTATGGGTATT
AATTAAGAAGAATAGGATACTATTTTTAGGATTATAAGTTCAATCCTATTGTTGGGTAAT
GTCTAATTTGACTAATCCACTTTAACTGACACACAACCATGTACTGTTAAGGATGAAAAG
CTTCTCAAAACAATTTCAGATCTGTTAAAGCTGGATTTTTCATCTCTCTTGAGAACAATT
AACACTGTTACAAGAAAAATAGGATCCTCTGTAATATATTCACCCAAAAAAATAGATGAA
GTAATTTCCTCAAGGGATTCTATTGCTCGTAATATGTATGATAGAATGTTTTCGTGGATA
GTTACTCGTTTGAATAATTCAATTAATATAAAAGGAGAAAATGGCAAAGAAAATGAAAAT
GAAGCTTAACTCTGCATAGGTTTACTTGATATTTTTGGCTTCGAGGTATTCGAAGAAAAC
TCTTTTGAGTAATTCTGTATTAATTATACCAACGAAAAACTATAATAATTGTACATACAA
TACGTATTTAAATCTGAAGAATAGGAATTTATTATTGAAGGACTAGAAAAATACATAAAT
TAACTAGGGTACAAAGATAATTAAAATATCATTGAAGTACTTGATAATCATCCTATTGGT
ATATTTTAGCTTATCGATGAGTCGTCAGCTCTCGCACAGTCTGATGATAAAAAGCTATAT
GAAAGCATCTATAGAATAAATAATGGAAAACCTGAAGTGAAGTTTGTAAATAAAGGAAAT
AAAAAAATTTTTTAGATTGTCCACACAGCAAAACCTGTAGATTATTCAATAGAAGGATTT
AGAGATAAAAATAAAGCTGAAATAAGCTAAGAGCTTTAGTTGACTATAGCTTAAAGTGAT
GATCCTATAGTTTCCTCAATATTTTTAGGAATTTAGGATATCAAAACTAGTAAGAATGAT
AAAATTGCAGCCATTAATTAGTAGTAGTATTAGACTAAAAGTACAAAGGAGAACAAATTT
TTAGGAAGTAAGTTTAGAGCCTAAATGAAGTAGCTCATGGATGAATTAATCTAATCAGAC
TGCCATTTTATAAGATGTATAAAACCAAATGAGACAAAAAGAGCAAATAATTTGATTCAA
GGATATGTATTGATTCAAATAAAATATTTAGGAGTTTTGTAAGCCATTTTAGCTAGAAAA
GAAGGATTTCCTTATAGAAAAGACTTCAAAGTACTATTTTAGCAATTTAGTGGCATGATT
GAAAAGTATAGAACTTTAAGCCTTTAAAAGATTGAGAGCCAGAATTTGGATTTAAAAAAT
ATATCCCAAGATATCCTCTAAGAGCTTTTCAAGAATAATAAAGATGTTTTAAAACATGTT
TTAGTTGGAAAAACAAAAATATTTGCAAAGGATGATTTTGGTAAAATCTTAGATGAGATG
CTGTTTAAATGGTATGAATAGAAGAAATCATTAATATTCAAAATAATTAAACAATTTTAA
GTTTACTAATTTAAAAAAAATCTAAAAGCTAATATGAAAATTCTAATGAAAGCTATCAAA
ACTTTTCAAAAAATTTCTGCTGTATTTAAAATGAAATGTCAAAGAAAGAGATTTTTACAA
GTTAAAAAATCAACAGCATTAATTTATAGCTTAATGTGTAAGAACTTTAAAAAACAATTT
ATAAAATAGTGGAATATTAAAACAAAATAAATTATAGTCGCATAAAAATAGAAAGAAAGA
GAATAAGCTGAATTATTAGCAAAATAAAAGCTGGAAGTAAAATAATAATAAAATGAGATG
AATAAAGATGAAATAGATCAATAAATTGATTAAAATTCTATTTTATGTAACACAATAGAT
AGAAAAGATAACTACAATACAAATTTATCATAAGAGTATGCTACTATAAGTAATTACAAT
ACATTTAATGCTGTCAACAATAACTAGAATAATATAGAAATGAAGCAAAACTATAAAGAT
TTGTAAGAAAATTACTTATCATCAAAAGGAGAAGCTGACATGAATGAGAAGATGAAATAA
GAATTTGAATAAATTTAGTAAAAGAACAAGGAAATTCTTTAAGATGCCCAATTAGAAGAT
GGACTGCCTTAAAAAATAAAGTTGAAATCAAAGGTCGAATCATTTTTAAATTTAGATAAT
CCTAATATGATCCGCCCAGGTCCTAATGAAAAGAGCAAAGATTGCTTAATTGATTTCAAT
GAATGCAATCAAGAAATGATCTAAAAAATTGAATAAAGTAATTATTTTGAAATAATTAGT
ACTATTGTGGTTATTAGAAAATATAATTCTACTGATCAAAATCCATTACAAAAAATGCTT
TCTTATTAAAAGAGGCAATTAAAAAAACCTCTCACAAGTATCGATAAGCATTATGAACCT
ATAGCAACGAAAGCTTTTTCTTATATGTTAAAATATGCTGGAGATAAACCTTGCGAAGAA
ATTCATCCCAGAATCATTGCTTGGAAGCTTGCTCAACTAATTCTTGATTAGGATGTACAA
GAAGTTACTGATGAAATATTCTTGTAGGTTATAAAATAGCTAACTAATAATTCAGAAGAA
AACATAGAGTAATATTTTAAAATTGCAGCTTTGATAGCTAGTTGCGTTGTTTTATCTTGT
CGCATAGTATTTCCATCAATGAATTTTTTCTTGGAATAAGCAAGGCATTATGAAAAAAGT
GGTAAAGAGAAATTGATGGAATGGTGCAAATTTATATTGTCCAGGATCGGAAATAGCTAT
AACTTTGATGAAAATATGTAATTTCCATGCTATATATTTAAAAGAGAAGAGATGCCATTA
AAAGAAGAGTTTATTGCCTTAGAGAATATGTTTTCTATTCAAATTCCAATTCACTTTTAT
GGAGACCGCTAAAAATACTTTAAGGTAGAATCATATACCAAAATTTGTAACATGGTGAGC
CAAATTGGCTTAGATTTAGAAATTCTTTATGATAAAAACAGTTATGGATTAGTCGAATAC
ATAACTGTTGATGCAGTTACTAAAGTTTAAATTTTAGATTTTGGAATGAGAATACTTGAT
TGGAAAGCCAAGAGGTATCGTGATAGATAACAATATTTACAAAAAAATCCAGGTAAGACT
TTTGAAATAAAACTATATTACCAATGTATCATTTTTCACAGCCCAAAATCTTAAAATATT
GACACTAATCTTATGACATATCTAACATATGTAAACGAGTATTTGCATGGATTGTATTTC
TTTGATTTTAACACAAACAAAGATTAAATATAAAATAAATTAATTGACTACCCAAAAGAA
ATTACAGAAATTGATTTTATTGTTGAGATGTCTGCAGCTAAGGTGCTAGCTGATTATAAA
ATCTATAAAAAGGAAAATATTATCTTACAAAATTGCATCCCAAATTCAAAAATTATTTTC
ATAAGACATGAAGTGTGGAAGGTCAAAATCGAAGATTAAATATGTAAGTTATAACAAATT
ATAAAAACTTAAAGACAAGCAAGGACTTATTTCTTGAATAGGATGAAAGAGTACTAAGGG
AAGTACTACTTTTCTTAAAAATTTTTCTGTAAATTTAGTTAGCACCCAAACTTTTTAGAA
TAAAAGGAAGCTATTTGCTTGACTAAATTAGGCTATGTGTACATTATTGAATAGCAAACA
TACAAGTAATTGTTAGAAATTTCTTATAGAGATATAAAAGATTTTAGCATTAATTTTTAT
TCCTAATCACTTGTTTTGTATACAGAATAAAATATTTATCAAATATTTTCTTAGTATGCT
TTGAATATATACTACAACATTAAATCGTATTGCTAAACTCTTGAAGAATTAGATAATGAT
AATATCTAAGAAGATAGAAATTGCTTTTAAACTAATGAAAATTTGCTAAATAATTCAAAT
GAAAAAACTGTTTATGATTCGAAAAATTCTAATCAAGATCAAAAATCAGATAATTCATAA
GTACCAATAAATATGATTGATAAAGTTAACGATGATACTATTGTAATCGAAATGCAATAA
TACTCATCTAATGATTGTAAAAAATAATAATCACAAAAGACTTAAAAAAATGTGAGAAAT
GGAAATTTAATCACTCCTGTTAAAAATTAAAGCACATACTAAAATGAACCTTAAATACCA
AATTATTCAGCTAATATTAATAGAGGAAGTGAAGAATATTTTGATAACTCTCCTAACTCA
TAATATTCAAGTGGCCAAAATAAATTAATTAATAACATTTAAAAGAATGATTAAAAATTA
TTTTAAGAATCAAAGATAAATCTAAATAAATAGTTACAAGAAGCTTAAAATGACACAAGT
AATATAGACCAAACTAACAGGTCATGCAATTTATATGAAAATCTGCTATGA

>TTHERM_00194050(gene)
CTAATCTCTTGTAATATCAGAATTAATTAAATAGTTGTTAAATAGTAAGTAAAAGTATTT
AAACCTAGAAGAGATACTTAAGTAGAAGGAGATGCTAGATATAAATACTACATGGATGAT
TCCGGACAGTGAGTGCTGGATTTAAGTAGGAGAAGAAGATGCATAAACATAAACAATGTT
TGTGAAAGCTAAAATAAAATAAAAACCCAGTCTTTCAAACATTAATAAGAATAATGTTTA
ACAATGTTTTGCTGACATAAAAGATGTAGAAGATAATCGATATGCTAATATAACAAAAGT
TAAAATAAATTCAGTTTATTAAGTAAACTAAGAAGTACCTTAAGGTTATAATGATATGGT
AGAAATGGATCACTTGAATTAAGCAGAAATTCTTATTAATTTATAAAGAAGATACGATTA
AGATTTAATATTTACATTTATAGGTCCTACACTTGTAGTGATGAATCCTTACAAGTTAAT
TCCAAAGCATTTTTCAAATGAAACTCGTAATATTTTTTCATAATAAGCAAAACACCAAGG
CTACATCGATTATAAAAAAAATGATCCACATACTTATGCTGTAGCTGCTTAATCATATTG
TAAGCTTTTTGAGTAAAATAAAAATCAAGCCATAGTAATATCAGGTGAGTCAGGTGCAGG
AAAGACTGAAAATGCCAAAATATGCATGTGTTTTCTTACAGGATTAAGCGGATAAGATGC
TGAAAGAAGACCTAGTATATAAAATAGTACTTCTCCAGCTAATAAAAATAAAAATAATAT
TGAAGATAGAATTTTGGGATGCAACCCTATATTAGAGGCGTTTGGAAATGCAAAAACTGT
TAGAAATGATAACAGCTCTCGTTTTGGAAAATTTGTATCGATTTAAGTAGGGAAAAAATC
AAGAAAAATTAAAGGTGCTACAATTTAGAACTATTTACTAGAAAAGAGTCGTGTTACCAC
TCCTGGTCCTGGAGAGCGCGGTTACCACATATTTTATCACTTACTCTACTGCGGATAAAA
CTAACTTTTAGAAAATTTATAATTGGTAGGTTAATATTCAAAACCACAAAATCTAAATTA
CTTAAAAGTTAGTAATTGTTATGAAGTATCAACTATAAATGACAATGCTCTGTTTAAAGA
AGTTGTTGAGGCCTTTCATACTATGGGTATTAATTAAGAAGAATAGGATACTATTTTTAG
GATTATAAGTTCAATCCTATTGTTGGGTAATGTCTAATTTGACTAATCCACTTTAACTGA
CACACAACCATGTACTGTTAAGGATGAAAAGCTTCTCAAAACAATTTCAGATCTGTTAAA
GCTGGATTTTTCATCTCTCTTGAGAACAATTAACACTGTTACAAGAAAAATAGGATCCTC
TGTAATATATTCACCCAAAAAAATAGATGAAGTAATTTCCTCAAGGGATTCTATTGCTCG
TAATATGTATGATAGAATGTTTTCGTGGATAGTTACTCGTTTGAATAATTCAATTAATAT
AAAAGGAGAAAATGGCAAAGAAAATGAAAATGAAGCTTAACTCTGCATAGGTTTACTTGA
TATTTTTGGCTTCGAGGTATTCGAAGAAAACTCTTTTGAGTAATTCTGTATTAATTATAC
CAACGAAAAACTATAATAATTGTACATACAATACGTATTTAAATCTGAAGAATAGGAATT
TATTATTGAAGGACTAGAAAAATACATAAATTAACTAGGGTACAAAGATAATTAAAATAT
CATTGAAGTACTTGATAATCATCCTATTGGTATATTTTAGCTTATCGATGAGTCGTCAGC
TCTCGCACAGTCTGATGATAAAAAGCTATATGAAAGCATCTATAGAATAAATAATGGAAA
ACCTGAAGTGAAGTTTGTAAATAAAGGAAATAAAAAAATTTTTTAGATTGTCCACACAGC
AAAACCTGTAGATTATTCAATAGAAGGATTTAGAGATAAAAATAAAGCTGAAATAAGCTA
AGAGCTTTAGTTGACTATAGCTTAAAGTGATGATCCTATAGTTTCCTCAATATTTTTAGG
AATTTAGGATATCAAAACTAGTAAGAATGATAAAATTGCAGCCATTAATTAGTAGTAGTA
TTAGACTAAAAGTACAAAGGAGAACAAATTTTTAGGAAGTAAGTTTAGAGCCTAAATGAA
GTAGCTCATGGATGAATTAATCTAATCAGACTGCCATTTTATAAGATGTATAAAACCAAA
TGAGACAAAAAGAGCAAATAATTTGATTCAAGGATATGTATTGATTCAAATAAAATATTT
AGGAGTTTTGTAAGCCATTTTAGCTAGAAAAGAAGGATTTCCTTATAGAAAAGACTTCAA
AGTACTATTTTAGCAATTTAGTGGCATGATTGAAAAGTATAGAACTTTAAGCCTTTAAAA
GATTGAGAGCCAGAATTTGGATTTAAAAAATATATCCCAAGATATCCTCTAAGAGCTTTT
CAAGAATAATAAAGATGTTTTAAAACATGTTTTAGTTGGAAAAACAAAAATATTTGCAAA
GGATGATTTTGGTAAAATCTTAGATGAGATGCTGTTTAAATGGTATGAATAGAAGAAATC
ATTAATATTCAAAATAATTAAACAATTTTAAGTTTACTAATTTAAAAAAAATCTAAAAGC
TAATATGAAAATTCTAATGAAAGCTATCAAAACTTTTCAAAAAATTTCTGCTGTATTTAA
AATGAAATGTCAAAGAAAGAGATTTTTACAAGTTAAAAAATCAACAGCATTAATTTATAG
CTTAATGTGTAAGAACTTTAAAAAACAATTTATAAAATAGTGGAATATTAAAACAAAATA
AATTATAGTCGCATAAAAATAGAAAGAAAGAGAATAAGCTGAATTATTAGCAAAATAAAA
GCTGGAAGTAAAATAATAATAAAATGAGATGAATAAAGATGAAATAGATCAATAAATTGA
TTAAAATTCTATTTTATGTAACACAATAGATAGAAAAGATAACTACAATACAAATTTATC
ATAAGAGTATGCTACTATAAGTAATTACAATACATTTAATGCTGTCAACAATAACTAGAA
TAATATAGAAATGAAGCAAAACTATAAAGATTTGTAAGAAAATTACTTATCATCAAAAGG
AGAAGCTGACATGAATGAGAAGATGAAATAAGAATTTGAATAAATTTAGTAAAAGAACAA
GGAAATTCTTTAAGATGCCCAATTAGAAGATGGACTGCCTTAAAAAATAAAGTTGAAATC
AAAGGTCGAATCATTTTTAAATTTAGATAATCCTAATATGATCCGCCCAGGTCCTAATGA
AAAGAGCAAAGATTGCTTAATTGATTTCAATGAATGCAATCAAGAAATGATCTAAAAAAT
TGAATAAAGTAATTATTTTGAAATAATTAGTACTATTGTGGTTATTAGAAAATATAATTC
TACTGATCAAAATCCATTACAAAAAATGCTTTCTTATTAAAAGAGGCAATTAAAAAAACC
TCTCACAAGTATCGATAAGCATTATGAACCTATAGCAACGAAAGCTTTTTCTTATATGTT
AAAATATGCTGGAGATAAACCTTGCGAAGAAATTCATCCCAGAATCATTGCTTGGAAGCT
TGCTCAACTAATTCTTGATTAGGATGTACAAGAAGTTACTGATGAAATATTCTTGTAGGT
TATAAAATAGCTAACTAATAATTCAGAAGAAAACATAGAGTAATATTTTAAAATTGCAGC
TTTGATAGCTAGTTGCGTTGTTTTATCTTGTCGCATAGTATTTCCATCAATGAATTTTTT
CTTGGAATAAGCAAGGCATTATGAAAAAAGTGGTAAAGAGAAATTGATGGAATGGTGCAA
ATTTATATTGTCCAGGATCGGAAATAGCTATAACTTTGATGAAAATATGTAATTTCCATG
CTATATATTTAAAAGAGAAGAGATGCCATTAAAAGAAGAGTTTATTGCCTTAGAGAATAT
GTTTTCTATTCAAATTCCAATTCACTTTTATGGAGACCGCTAAAAATACTTTAAGGTAGA
ATCATATACCAAAATTTGTAACATGGTGAGCCAAATTGGCTTAGATTTAGAAATTCTTTA
TGATAAAAACAGTTATGGATTAGTCGAATACATAACTGTTGATGCAGTTACTAAAGTTTA
AATTTTAGATTTTGGAATGAGAATACTTGATTGGAAAGCCAAGAGGTATCGTGATAGATA
ACAATATTTACAAAAAAATCCAGGTAAGACTTTTGAAATAAAACTATATTACCAATGTAT
CATTTTTCACAGCCCAAAATCTTAAAATATTGACACTAATCTTATGACATATCTAACATA
TGTAAACGAGTATTTGCATGGATTGTATTTCTTTGATTTTAACACAAACAAAGATTAAAT
ATAAAATAAATTAATTGACTACCCAAAAGAAATTACAGAAATTGATTTTATTGTTGAGAT
GTCTGCAGCTAAGGTGCTAGCTGATTATAAAATCTATAAAAAGGAAAATATTATCTTACA
AAATTGCATCCCAAATTCAAAAATTATTTTCATAAGACATGAAGTGTGGAAGGTCAAAAT
CGAAGATTAAATATGTAAGTTATAACAAATTATAAAAACTTAAAGACAAGCAAGGACTTA
TTTCTTGAATAGGATGAAAGAGTACTAAGGGAAGTACTACTTTTCTTAAAAATTTTTCTG
TAAATTTAGTTAGCACCCAAACTTTTTAGAATAAAAGGAAGCTATTTGCTTGACTAAATT
AGGCTATGTGTACATTATTGAATAGCAAACATACAAGTAATTGTTAGAAATTTCTTATAG
AGATATAAAAGATTTTAGCATTAATTTTTATTCCTAATCACTTGTTTTGTATACAGAATA
AAATATTTATCAAATATTTTCTTAGTATGCTTTGAATATATACTACAACATTAAATCGTA
TTGCTAAACTCTTGAAGAATTAGATAATGATAATATCTAAGAAGATAGAAATTGCTTTTA
AACTAATGAAAATTTGCTAAATAATTCAAATGAAAAAACTGTTTATGATTCGAAAAATTC
TAATCAAGATCAAAAATCAGATAATTCATAAGTACCAATAAATATGATTGATAAAGTTAA
CGATGATACTATTGTAATCGAAATGCAATAATACTCATCTAATGATTGTAAAAAATAATA
ATCACAAAAGACTTAAAAAAATGTGAGAAATGGAAATTTAATCACTCCTGTTAAAAATTA
AAGCACATACTAAAATGAACCTTAAATACCAAATTATTCAGCTAATATTAATAGAGGAAG
TGAAGAATATTTTGATAACTCTCCTAACTCATAATATTCAAGTGGCCAAAATAAATTAAT
TAATAACATTTAAAAGAATGATTAAAAATTATTTTAAGAATCAAAGATAAATCTAAATAA
ATAGTTACAAGAAGCTTAAAATGACACAAGTAATATAGACCAAACTAACAGGTCATGCAA
TTTATATGAAAATCTGCTATGAAATAATTAATTAAAATTTTAAATAAATGAATTAATTTA
ATTAAAAATTACTTTAATATCATTTGATTAGATTATTTTTCATAAATGAATGATGGATGG
ATCACTTTTTAATTAAATTATTAATTATATTTTATAAAAATTAATTCATTCATATTTATT
TACAAAAATAATTAATATATTATAATTCAAAT

>TTHERM_00194050(protein)
MLDINTTWMIPDSECWIQVGEEDAQTQTMFVKAKIKQKPSLSNINKNNVQQCFADIKDVE
DNRYANITKVKINSVYQVNQEVPQGYNDMVEMDHLNQAEILINLQRRYDQDLIFTFIGPT
LVVMNPYKLIPKHFSNETRNIFSQQAKHQGYIDYKKNDPHTYAVAAQSYCKLFEQNKNQA
IVISGESGAGKTENAKICMCFLTGLSGQDAERRPSIQNSTSPANKNKNNIEDRILGCNPI
LEAFGNAKTVRNDNSSRFGKFVSIQVGKKSRKIKGATIQNYLLEKSRVTTPGPGERGYHI
FYHLLYCGQNQLLENLQLVGQYSKPQNLNYLKVSNCYEVSTINDNALFKEVVEAFHTMGI
NQEEQDTIFRIISSILLLGNVQFDQSTLTDTQPCTVKDEKLLKTISDLLKLDFSSLLRTI
NTVTRKIGSSVIYSPKKIDEVISSRDSIARNMYDRMFSWIVTRLNNSINIKGENGKENEN
EAQLCIGLLDIFGFEVFEENSFEQFCINYTNEKLQQLYIQYVFKSEEQEFIIEGLEKYIN
QLGYKDNQNIIEVLDNHPIGIFQLIDESSALAQSDDKKLYESIYRINNGKPEVKFVNKGN
KKIFQIVHTAKPVDYSIEGFRDKNKAEISQELQLTIAQSDDPIVSSIFLGIQDIKTSKND
KIAAINQQQYQTKSTKENKFLGSKFRAQMKQLMDELIQSDCHFIRCIKPNETKRANNLIQ
GYVLIQIKYLGVLQAILARKEGFPYRKDFKVLFQQFSGMIEKYRTLSLQKIESQNLDLKN
ISQDILQELFKNNKDVLKHVLVGKTKIFAKDDFGKILDEMLFKWYEQKKSLIFKIIKQFQ
VYQFKKNLKANMKILMKAIKTFQKISAVFKMKCQRKRFLQVKKSTALIYSLMCKNFKKQF
IKQWNIKTKQIIVAQKQKEREQAELLAKQKLEVKQQQNEMNKDEIDQQIDQNSILCNTID
RKDNYNTNLSQEYATISNYNTFNAVNNNQNNIEMKQNYKDLQENYLSSKGEADMNEKMKQ
EFEQIQQKNKEILQDAQLEDGLPQKIKLKSKVESFLNLDNPNMIRPGPNEKSKDCLIDFN
ECNQEMIQKIEQSNYFEIISTIVVIRKYNSTDQNPLQKMLSYQKRQLKKPLTSIDKHYEP
IATKAFSYMLKYAGDKPCEEIHPRIIAWKLAQLILDQDVQEVTDEIFLQVIKQLTNNSEE
NIEQYFKIAALIASCVVLSCRIVFPSMNFFLEQARHYEKSGKEKLMEWCKFILSRIGNSY
NFDENMQFPCYIFKREEMPLKEEFIALENMFSIQIPIHFYGDRQKYFKVESYTKICNMVS
QIGLDLEILYDKNSYGLVEYITVDAVTKVQILDFGMRILDWKAKRYRDRQQYLQKNPGKT
FEIKLYYQCIIFHSPKSQNIDTNLMTYLTYVNEYLHGLYFFDFNTNKDQIQNKLIDYPKE
ITEIDFIVEMSAAKVLADYKIYKKENIILQNCIPNSKIIFIRHEVWKVKIEDQICKLQQI
IKTQRQARTYFLNRMKEYQGKYYFSQKFFCKFSQHPNFLEQKEAICLTKLGYVYIIEQQT
YKQLLEISYRDIKDFSINFYSQSLVLYTEQNIYQIFSQYALNIYYNIKSYCQTLEELDND
NIQEDRNCFQTNENLLNNSNEKTVYDSKNSNQDQKSDNSQVPINMIDKVNDDTIVIEMQQ
YSSNDCKKQQSQKTQKNVRNGNLITPVKNQSTYQNEPQIPNYSANINRGSEEYFDNSPNS
QYSSGQNKLINNIQKNDQKLFQESKINLNKQLQEAQNDTSNIDQTNRSCNLYENLL